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Items: 49

1.

CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage.

Abe H, Jitsuki S, Nakajima W, Murata Y, Jitsuki-Takahashi A, Katsuno Y, Tada H, Sano A, Suyama K, Mochizuki N, Komori T, Masuyama H, Okuda T, Goshima Y, Higo N, Takahashi T.

Science. 2018 Apr 6;360(6384):50-57. doi: 10.1126/science.aao2300.

PMID:
29622647
2.

p53-independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells.

Sharma K, Vu TT, Cook W, Naseri M, Zhan K, Nakajima W, Harada H.

Mol Oncol. 2018 Jun;12(6):788-798. doi: 10.1002/1878-0261.12172. Epub 2018 Apr 17.

3.

Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex.

Tada H, Miyazaki T, Takemoto K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Taguchi A, Kawai H, Komiya K, Suyama K, Abe H, Sano A, Takahashi T.

Sci Rep. 2017 Aug 16;7(1):8471. doi: 10.1038/s41598-017-08849-3.

4.

Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1.

Suzuki J, Nakajima W, Suzuki H, Asano Y, Tanaka N.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):1334-1340. doi: 10.1016/j.bbrc.2016.12.037. Epub 2016 Dec 7.

PMID:
27939888
5.

Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex.

Tada H, Miyazaki T, Takemoto K, Takase K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Komiya K, Suyama K, Sano A, Taguchi A, Takahashi T.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E7097-E7105. doi: 10.1073/pnas.1606351113. Epub 2016 Oct 25.

6.

DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex.

Nakajima W, Sharma K, Lee JY, Maxim NT, Hicks MA, Vu TT, Luu A, Yeudall WA, Tanaka N, Harada H.

Oncotarget. 2016 Jun 14;7(24):36353-36365. doi: 10.18632/oncotarget.9217.

7.

Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.

Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N.

Biochem Biophys Res Commun. 2016 Apr 29;473(2):490-6. doi: 10.1016/j.bbrc.2016.03.053. Epub 2016 Mar 18.

PMID:
26996126
8.

Sustained Enhancement of Lateral Inhibitory Circuit Maintains Cross Modal Cortical Reorganization.

Nakajima W, Jitsuki S, Sano A, Takahashi T.

PLoS One. 2016 Feb 10;11(2):e0149068. doi: 10.1371/journal.pone.0149068. eCollection 2016.

9.

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination.

Ham J, Costa C, Sano R, Lochmann TL, Sennott EM, Patel NU, Dastur A, Gomez-Caraballo M, Krytska K, Hata AN, Floros KV, Hughes MT, Jakubik CT, Heisey DA, Ferrell JT, Bristol ML, March RJ, Yates C, Hicks MA, Nakajima W, Gowda M, Windle BE, Dozmorov MG, Garnett MJ, McDermott U, Harada H, Taylor SM, Morgan IM, Benes CH, Engelman JA, Mossé YP, Faber AC.

Cancer Cell. 2016 Feb 8;29(2):159-72. doi: 10.1016/j.ccell.2016.01.002.

10.

Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer.

Nakajima W, Sharma K, Hicks MA, Le N, Brown R, Krystal GW, Harada H.

Cancer Biol Ther. 2016;17(1):27-35. doi: 10.1080/15384047.2015.1108485.

11.

Nogo Receptor Signaling Restricts Adult Neural Plasticity by Limiting Synaptic AMPA Receptor Delivery.

Jitsuki S, Nakajima W, Takemoto K, Sano A, Tada H, Takahashi-Jitsuki A, Takahashi T.

Cereb Cortex. 2016 Jan;26(1):427-439. doi: 10.1093/cercor/bhv232. Epub 2015 Oct 15.

12.

Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy.

Chakradeo S, Sharma K, Alhaddad A, Bakhshwin D, Le N, Harada H, Nakajima W, Yeudall WA, Torti SV, Torti FM, Gewirtz DA.

Mol Pharmacol. 2015 May;87(5):803-14. doi: 10.1124/mol.114.095273. Epub 2015 Feb 9.

13.

p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.

Yamauchi S, Hou YY, Guo AK, Hirata H, Nakajima W, Yip AK, Yu CH, Harada I, Chiam KH, Sawada Y, Tanaka N, Kawauchi K.

J Cell Biol. 2014 Mar 31;204(7):1191-207. doi: 10.1083/jcb.201309107. Epub 2014 Mar 24.

14.

Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer.

Nakajima W, Hicks MA, Tanaka N, Krystal GW, Harada H.

Cell Death Dis. 2014 Feb 13;5:e1052. doi: 10.1038/cddis.2014.6.

15.

Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.

Miller AV, Hicks MA, Nakajima W, Richardson AC, Windle JJ, Harada H.

PLoS One. 2013;8(4):e60685. doi: 10.1371/journal.pone.0060685. Epub 2013 Apr 5.

16.

Disrupted cortical function underlies behavior dysfunction due to social isolation.

Miyazaki T, Takase K, Nakajima W, Tada H, Ohya D, Sano A, Goto T, Hirase H, Malinow R, Takahashi T.

J Clin Invest. 2012 Jul;122(7):2690-701. doi: 10.1172/JCI63060. Epub 2012 Jun 18. Erratum in: J Clin Invest. 2014 Jun 2;124(6):2807.

17.

[A case of endotracheal intubation in prone position utilizing PENTAX-Airwayscope for morbidly obese patient].

Suzuki H, Nakajima W, Aoyagi M, Takahashi M, Kuzuta T, Osaki M.

Masui. 2012 Apr;61(4):384-6. Japanese.

PMID:
22590940
18.

Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between Puma and Mcl-1.

Nakajima W, Tanaka N.

Biochem Biophys Res Commun. 2011 Oct 7;413(4):643-8. doi: 10.1016/j.bbrc.2011.09.036. Epub 2011 Sep 14.

PMID:
21945433
19.

Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3.

Ando M, Uehara I, Kogure K, Asano Y, Nakajima W, Abe Y, Kawauchi K, Tanaka N.

J Nippon Med Sch. 2010 Apr;77(2):97-105.

20.

[Anesthetic management using esmolol for arthroscopic synovectomy in a patient with thyroid storm].

Torigoe K, Suzuki H, Nakajima W, Takahashi M, Aoyagi M.

Masui. 2010 Feb;59(2):257-9. Japanese.

PMID:
20169973
21.

5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis.

Yagi S, Oda-Sato E, Uehara I, Asano Y, Nakajima W, Takeshita T, Tanaka N.

Cancer Invest. 2008 Aug;26(7):680-8. doi: 10.1080/07357900701840212.

PMID:
18608210
22.

Aseptic meningitis associated with cephalosporins in an infant with trisomy 21.

Nakajima W, Ishida A, Takahashi M, Sato Y, Ito T, Takada G.

J Child Neurol. 2007 Jun;22(6):780-2.

PMID:
17641271
23.
24.

Intraventricular ascorbic acid administration decreases hypoxic-ischemic brain injury in newborn rats.

Miura S, Ishida A, Nakajima W, Ohmura A, Kawamura M, Takada G.

Brain Res. 2006 Jun 20;1095(1):159-66. Epub 2006 May 24.

PMID:
16725128
25.

Prolonged hypothermia protects neonatal rat brain against hypoxic-ischemia by reducing both apoptosis and necrosis.

Ohmura A, Nakajima W, Ishida A, Yasuoka N, Kawamura M, Miura S, Takada G.

Brain Dev. 2005 Oct;27(7):517-26.

PMID:
15899566
26.

Calpain inhibitor MDL 28170 protects hypoxic-ischemic brain injury in neonatal rats by inhibition of both apoptosis and necrosis.

Kawamura M, Nakajima W, Ishida A, Ohmura A, Miura S, Takada G.

Brain Res. 2005 Mar 10;1037(1-2):59-69.

PMID:
15777753
27.

Neuroprotection of edaravone on hypoxic-ischemic brain injury in neonatal rats.

Yasuoka N, Nakajima W, Ishida A, Takada G.

Brain Res Dev Brain Res. 2004 Jul 19;151(1-2):129-39.

PMID:
15246699
28.

Good outcome for infant of mother treated with chemotherapy for ewing sarcoma at 25 to 30 weeks' gestation.

Nakajima W, Ishida A, Takahashi M, Hirayama M, Washino N, Ogawa M, Takahashi S, Okada K.

J Pediatr Hematol Oncol. 2004 May;26(5):308-11. Review.

PMID:
15111784
29.

Mechanisms of hypoxic neurodegeneration in the developing brain.

Johnston MV, Nakajima W, Hagberg H.

Neuroscientist. 2002 Jun;8(3):212-20. Review.

PMID:
12061501
30.

Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice.

Gabrielson KL, Hogue BA, Bohr VA, Cardounel AJ, Nakajima W, Kofler J, Zweier JL, Rodriguez ER, Martin LJ, de Souza-Pinto NC, Bressler J.

Am J Pathol. 2001 Oct;159(4):1507-20.

31.

Neurobiology of hypoxic-ischemic injury in the developing brain.

Johnston MV, Trescher WH, Ishida A, Nakajima W.

Pediatr Res. 2001 Jun;49(6):735-41. Review.

PMID:
11385130
32.

Delayed increase in neuronal nitric oxide synthase immunoreactivity in thalamus and other brain regions after hypoxic-ischemic injury in neonatal rats.

Ishida A, Ishiwa S, Trescher WH, Nakajima W, Lange MS, Blue ME, Johnston MV.

Exp Neurol. 2001 Apr;168(2):323-33.

PMID:
11259120
33.

Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat.

Nakajima W, Ishida A, Lange MS, Gabrielson KL, Wilson MA, Martin LJ, Blue ME, Johnston MV.

J Neurosci. 2000 Nov 1;20(21):7994-8004.

34.

Novel treatments after experimental brain injury.

Johnston MV, Trescher WH, Ishida A, Nakajima W.

Semin Neonatol. 2000 Feb;5(1):75-86. Review.

PMID:
10802752
35.
36.

Immunohistochemical study on transforming growth factor-beta1 expression in liver fibrosis of Down's syndrome with transient abnormal myelopoiesis.

Arai H, Ishida A, Nakajima W, Nishinomiya F, Yamazoe A, Takada G.

Hum Pathol. 1999 Apr;30(4):474-6.

PMID:
10208471
37.

Anoxic and hypoxic immature rat model for measurement of monoamine using in vivo microdialysis.

Nakajima W, Ishida A, Takada G.

Brain Res Brain Res Protoc. 1999 Jan;3(3):252-6.

PMID:
9974139
38.

Effect of N-methyl-D-aspartate and potassium on striatal monoamine metabolism in immature rat: an in vivo microdialysis study.

Nakajima W, Ishida A, Ogasawara M, Takada G.

Neurochem Res. 1998 Sep;23(9):1159-65.

PMID:
9712185
39.

Short-term fasting alters neonatal rat striatal dopamine levels and serotonin metabolism: an in vivo microdialysis study.

Ishida A, Nakajima W, Takada G.

Brain Res Dev Brain Res. 1997 Dec 19;104(1-2):131-6.

PMID:
9466715
40.

Methaemoglobinaemia after inhalation of nitric oxide in infant with pulmonary hypertension.

Nakajima W, Ishida A, Arai H, Takada G.

Lancet. 1997 Oct 4;350(9083):1002-3. No abstract available.

PMID:
9329519
41.
42.

Cranial computed tomography scans of premature babies predict their eventual learning disabilities.

Ishida A, Nakajima W, Arai H, Takahashi Y, Iijima R, Sawaishi Y, Goto R, Takada G.

Pediatr Neurol. 1997 May;16(4):319-22.

PMID:
9258966
43.

A case of neonatal choriocarcinoma.

Kishkurno S, Ishida A, Takahashi Y, Arai H, Nakajima W, Abe T, Takada G.

Am J Perinatol. 1997 Feb;14(2):79-82.

PMID:
9259903
44.
45.

Partial 6p trisomy with abnormal ABR and hypogenesis of the corpus callosum.

Nakajima W, Sakemi K, Komatsu K, Okamura T.

Tohoku J Exp Med. 1995 Apr;175(4):279-84.

46.

A preterm infant with secondary carnitine deficiency due to MCT formula--effective treatment of L-carnitine.

Ishida A, Goto A, Takahashi Y, Nakajima W, Arai H, Tazawa Y, Takada G.

Tohoku J Exp Med. 1994 Jan;172(1):59-64.

47.

Two siblings with partial trisomy 15 and monosomy 21 associated with central nervous system anomalies.

Ishida A, Sawaishi Y, Goto A, Takahashi Y, Arai H, Nakajima W, Onozaki M, Takada G.

Tohoku J Exp Med. 1993 Dec;171(4):277-83.

48.

[Trial in improvement of the work environment].

Asami M, Tanbano M, Nakajima W, Aoki E, Kudo Y, Itoman H.

Sogo Kango. 1971 Spring;6(2):54-66. Japanese. No abstract available.

PMID:
5209735

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