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Uncovering the mouse olfactory long non-coding transcriptome with a novel machine-learning model.

Camargo AP, Nakahara TS, Firmino LER, Netto PHM, do Nascimento JBP, Donnard ER, Galante PAF, Carazzolle MF, Malnic B, Papes F.

DNA Res. 2019 Jul 18. pii: dsz015. doi: 10.1093/dnares/dsz015. [Epub ahead of print]


Attenuation of Retinal Endothelial Vasodilator Function in a Rat Model of Retinopathy of Prematurity.

Nakano A, Mori A, Arima S, Asano D, Morita A, Sakamoto K, Nagamitsu T, Nakahara T.

Curr Eye Res. 2019 Jul 18:1-9. doi: 10.1080/02713683.2019.1641825. [Epub ahead of print]


Does mechanical scratching cause the recruitment of T-helper 17 cells in atopic dermatitis?

Furue K, Ito T, Tsuji G, Esaki H, Kido-Nakahara M, Nakahara T, Furue M.

J Dermatol. 2019 Jul 11. doi: 10.1111/1346-8138.15011. [Epub ahead of print] No abstract available.


Response to: Effects of breathing motion on PET acquisitions: step and shoot versus continuous bed motion.

Owaki Y, Nakahara T, Shimizu T, Smith AM, Luk WK, Inoue K, Fukushi M, Nakajima K.

Nucl Med Commun. 2019 Aug;40(8):873-874. doi: 10.1097/MNM.0000000000001045. No abstract available.


Three-dimensional radiologic-pathologic correlation of medication-related osteonecrosis of the jaw using 3D bone SPECT/CT imaging.

Miyashita H, Kameyama K, Morita M, Nakagawa T, Nakahara T.

Dentomaxillofac Radiol. 2019 Jul 11:20190208. doi: 10.1259/dmfr.20190208. [Epub ahead of print]


Scratching Counteracts IL-13 Signaling by Upregulating the Decoy Receptor IL-13Rα2 in Keratinocytes.

Ulzii D, Kido-Nakahara M, Nakahara T, Tsuji G, Furue K, Hashimoto-Hachiya A, Furue M.

Int J Mol Sci. 2019 Jul 6;20(13). pii: E3324. doi: 10.3390/ijms20133324.


An Ex-Vivo Culture System of Ovarian Cancer Faithfully Recapitulating the Pathological Features of Primary Tumors.

Ghani FI, Dendo K, Watanabe R, Yamada K, Yoshimatsu Y, Yugawa T, Nakahara T, Tanaka K, Yoshida H, Yoshida M, Ishikawa M, Goshima N, Kato T, Kiyono T.

Cells. 2019 Jun 26;8(7). pii: E644. doi: 10.3390/cells8070644.


Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib.

Kodama K, Kawaoka T, Namba M, Uchikawa S, Ohya K, Morio K, Nakahara T, Murakami E, Yamauchi M, Hiramatsu A, Imamura M, Chayama K, Aikata H.

Oncology. 2019 Jun 26:1-7. doi: 10.1159/000499715. [Epub ahead of print]


Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice.

Osawa M, Uchida T, Imamura M, Teraoka Y, Fujino H, Nakahara T, Ono A, Murakami E, Kawaoka T, Miki D, Tsuge M, Hiramatsu A, Abe-Chayama H, Hayes CN, Makokha GN, Aikata H, Ishida Y, Tateno C, Miyayama Y, Hijikata M, Chayama K.

J Gen Virol. 2019 Jul;100(7):1123-1131. doi: 10.1099/jgv.0.001268. Epub 2019 Jun 14.


Pathogenesis of Atopic Dermatitis: Current Paradigm.

Furue M, Ulzii D, Vu YH, Tsuji G, Kido-Nakahara M, Nakahara T.

Iran J Immunol. 2019 Jun;16(2):97-107. doi: 10.22034/IJI.2019.80253.


Binimetinib, a novel MEK1/2 inhibitor, exerts anti-leukemic effects under inactive status of PI3Kinase/Akt pathway.

Sakakibara K, Tsujioka T, Kida JI, Kurozumi N, Nakahara T, Suemori SI, Kitanaka A, Arao Y, Tohyama K.

Int J Hematol. 2019 Aug;110(2):213-227. doi: 10.1007/s12185-019-02667-1. Epub 2019 May 25.


Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance.

Murakami I, Egawa N, Griffin H, Yin W, Kranjec C, Nakahara T, Kiyono T, Doorbar J.

PLoS Pathog. 2019 May 13;15(5):e1007755. doi: 10.1371/journal.ppat.1007755. eCollection 2019 May.


Role of Neuron⁻Glia Signaling in Regulation of Retinal Vascular Tone in Rats.

Someya E, Akagawa M, Mori A, Morita A, Yui N, Asano D, Sakamoto K, Nakahara T.

Int J Mol Sci. 2019 Apr 20;20(8). pii: E1952. doi: 10.3390/ijms20081952.


Simple patient-specific instrument for intraoral vertical ramus osteotomy.

Ohtani T, Habu M, Nakahara T, Tominaga K, Yoshioka I.

Br J Oral Maxillofac Surg. 2019 May;57(4):381-382. doi: 10.1016/j.bjoms.2019.03.010. Epub 2019 Apr 6. No abstract available.


Clinical value of 3D SPECT/CT imaging for assessing jaw bone invasion in oral cancer patients.

Miyashita H, Nakahara T, Asoda S, Kameyama K, Kawaida M, Enomoto R, Shiba H, Jinzaki M, Kawana H, Nakagawa T.

J Craniomaxillofac Surg. 2019 Jul;47(7):1139-1146. doi: 10.1016/j.jcms.2019.03.013. Epub 2019 Mar 18.


IgG4-related periarteritis of the carotid artery.

Matsusaka Y, Kikuchi T, Nakahara T, Iwabuchi Y, Jinzaki M.

QJM. 2019 Mar 21. pii: hcz068. doi: 10.1093/qjmed/hcz068. [Epub ahead of print] No abstract available.


Bone SPECT-based segmented attenuation correction for quantitative analysis of bone metastasis (B-SAC): comparison with CT-based attenuation correction.

Nakahara T, Owaki Y, Shindou T, Nakajima K, Jinzaki M.

EJNMMI Res. 2019 Mar 19;9(1):27. doi: 10.1186/s13550-019-0501-1.


Involvement of matrix metalloproteinases in capillary degeneration following NMDA-induced neurotoxicity in the neonatal rat retina.

Asano D, Morita A, Mori A, Sakamoto K, Ishii K, Nakahara T.

Exp Eye Res. 2019 May;182:101-108. doi: 10.1016/j.exer.2019.03.005. Epub 2019 Mar 16.


Most Important Prognostic Values to Predict Major Adverse Cardiovascular, Cerebrovascular, and Renal Events in Patients with Chronic Kidney Disease Including Hemodialysis for 2 Years.

Toyama T, Kasama S, Sato M, Sano H, Ueda T, Sasaki T, Nakahara T, Higuchi T, Tsushima Y, Kurabayashi M.

Cardiology. 2019;142(1):14-23. doi: 10.1159/000496330. Epub 2019 Mar 13.


Levocarnitine Use Is Associated With Improvement in Sarcopenia in Patients With Liver Cirrhosis.

Hiramatsu A, Aikata H, Uchikawa S, Ohya K, Kodama K, Nishida Y, Daijo K, Osawa M, Teraoka Y, Honda F, Inagaki Y, Morio K, Morio R, Fujino H, Nakahara T, Murakami E, Yamauchi M, Kawaoka T, Miki D, Tsuge M, Imamura M, Tanaka J, Chayama K.

Hepatol Commun. 2019 Jan 22;3(3):348-355. doi: 10.1002/hep4.1309. eCollection 2019 Mar.


18F-Fluoride Positron Emission Tomographic Imaging of Penile Arteries and Erectile Dysfunction.

Nakahara T, Narula J, Tijssen JGP, Agarwal S, Chowdhury MM, Coughlin PA, Dweck MR, Rudd JHF, Jinzaki M, Mulhall J, Strauss HW.

J Am Coll Cardiol. 2019 Apr 2;73(12):1386-1394. doi: 10.1016/j.jacc.2018.10.076. Epub 2019 Mar 4.


Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.

Tsushima K, Tsuge M, Hiraga N, Uchida T, Murakami E, Makokha GN, Kurihara M, Nomura M, Hiyama Y, Fujino H, Ono A, Nakahara T, Yamauchi M, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Aikata H, Hayes CN, Chayama K.

J Gastroenterol. 2019 Jul;54(7):650-659. doi: 10.1007/s00535-019-01558-w. Epub 2019 Feb 21.


Activator of G-protein signaling 8 is involved in VEGF-induced choroidal neovascularization.

Hayashi H, Mamun AA, Takeyama M, Yamamura A, Zako M, Yagasaki R, Nakahara T, Kamei M, Sato M.

Sci Rep. 2019 Feb 7;9(1):1560. doi: 10.1038/s41598-018-38067-4.


Probucol Slows the Progression of Cataracts in Streptozotocin-Induced Hyperglycemic Rats.

Higashi K, Mori A, Sakamoto K, Ishii K, Nakahara T.

Pharmacology. 2019;103(3-4):212-219. doi: 10.1159/000496055. Epub 2019 Feb 5.


Percutaneous transvenous shunt occlusion for portosystemic encephalopathy due to lenvatinib administration to a patient with hepatocellular carcinoma and portosystemic shunt.

Namba M, Kawaoka T, Aikata H, Kodama K, Uchikawa S, Ohya K, Morio K, Fujino H, Nakahara T, Murakami E, Yamauchi M, Tsuge M, Hiramatsu A, Imamura M, Baba Y, Awai K, Chayama K.

Clin J Gastroenterol. 2019 Jan 31. doi: 10.1007/s12328-019-00938-2. [Epub ahead of print]


Impact of a combination of quantitative indices representing uptake intensity, shape, and asymmetry in DAT SPECT using machine learning: comparison of different volume of interest settings.

Iwabuchi Y, Nakahara T, Kameyama M, Yamada Y, Hashimoto M, Matsusaka Y, Osada T, Ito D, Tabuchi H, Jinzaki M.

EJNMMI Res. 2019 Jan 28;9(1):7. doi: 10.1186/s13550-019-0477-x.


Can we predict amyloid deposition by objective cognition and regional cerebral blood flow in patients with subjective cognitive decline?

Funaki K, Nakajima S, Noda Y, Wake T, Ito D, Yamagata B, Yoshizaki T, Kameyama M, Nakahara T, Murakami K, Jinzaki M, Mimura M, Tabuchi H.

Psychogeriatrics. 2019 Jul;19(4):325-332. doi: 10.1111/psyg.12397. Epub 2019 Jan 27.


Focal 123I-MIBG Uptake in the Medial Segment of the Normal Liver.

Matsusaka Y, Nakahara T, Iwabuchi Y, Minami Y, Jinzaki M.

Clin Nucl Med. 2019 Mar;44(3):e170-e171. doi: 10.1097/RLU.0000000000002449.


Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression.

Kodama Y, Harinath D, Mihara-Tomiyama N, Tominaga N, Ide Y, Nakahara T, Maeda M, Igarashi M, D'Armiento J, Chada K, Imai K.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):1008-1014. doi: 10.1016/j.bbrc.2019.01.017. Epub 2019 Jan 14.


Correction: Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study.

Tatsukawa Y, Tsuge M, Kawakami Y, Hiyama Y, Murakami E, Kurihara M, Nomura M, Tsushima K, Uchida T, Nakahara T, Miki D, Kawaoka T, Abe-Chayama H, Imamura M, Aikata H, Ochi H, Hayes CN, Kawakami H, Chayama K.

Antivir Ther. 2019;23(8):709. doi: 10.3851/IMP3289. No abstract available.


Cross-sectional multicenter observational study of psoriatic arthritis in Japanese patients: Relationship between skin and joint symptoms and results of treatment with tumor necrosis factor-α inhibitors.

Tsuruta N, Narisawa Y, Imafuku S, Ito K, Yamaguchi K, Miyagi T, Takahashi K, Fukamatsu H, Morizane S, Koketsu H, Yamaguchi M, Hino R, Nakamura M, Ohyama B, Ohata C, Kuwashiro M, Sato T, Saito K, Kaneko S, Yonekura K, Hayashi H, Yanase T, Morimoto K, Sugita K, Yanagihara S, Kikuchi S, Mitoma C, Nakahara T, Furue M, Okazaki F.

J Dermatol. 2019 Mar;46(3):193-198. doi: 10.1111/1346-8138.14745. Epub 2019 Jan 10.


Variability in Treatment for Carbon Monoxide Poisoning in Japan: A Multicenter Retrospective Survey.

Fujita M, Oda Y, Kaneda K, Kawamura Y, Nakahara T, Todani M, Yagi T, Koga Y, Tsuruta R.

Emerg Med Int. 2018 Dec 4;2018:2159147. doi: 10.1155/2018/2159147. eCollection 2018.


Periostin Links Skin Inflammation to Melanoma Progression in Humans and Mice.

Ohno F, Nakahara T, Kido-Nakahara M, Ito T, Nunomura S, Izuhara K, Furue M.

Int J Mol Sci. 2019 Jan 4;20(1). pii: E169. doi: 10.3390/ijms20010169.


Measurement of trihydroxy-linoleic acids in stratum corneum by tape-stripping: Possible biomarker of barrier function in atopic dermatitis.

Chiba T, Nakahara T, Kohda F, Ichiki T, Manabe M, Furue M.

PLoS One. 2019 Jan 4;14(1):e0210013. doi: 10.1371/journal.pone.0210013. eCollection 2019.


HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease.

Fujii H, Imajo K, Yoneda M, Nakahara T, Hyogo H, Takahashi H, Hara T, Tanaka S, Sumida Y, Eguchi Y, Chayama K, Nakajima A, Nishimoto N, Kawada N; Japan Study Group of Nonalcoholic Fatty Liver Disease.

J Gastroenterol Hepatol. 2019 Jan 1. doi: 10.1111/jgh.14595. [Epub ahead of print]


Treatment satisfaction in atopic dermatitis relates to patient-reported severity: A cross-sectional study.

Nakahara T, Fujita H, Arima K, Taguchi Y, Motoyama S, Furue M.

Allergy. 2019 Jun;74(6):1179-1181. doi: 10.1111/all.13712. Epub 2019 Jan 17. No abstract available.


Early experience of seven hepatocellular carcinoma cases treated with regorafenib.

Uchikawa S, Kawaoka T, Aikata H, Kodama K, Inagaki Y, Hatooka M, Morio K, Nakahara T, Murakami E, Hiramatsu A, Tsuge M, Imamura M, Kawakami Y, Chayama K.

Clin Case Rep. 2018 Oct 11;6(11):2217-2223. doi: 10.1002/ccr3.1791. eCollection 2018 Nov.


Role of P2X3 receptors in scratching behavior in mouse models.

Shiratori-Hayashi M, Hasegawa A, Toyonaga H, Andoh T, Nakahara T, Kido-Nakahara M, Furue M, Kuraishi Y, Inoue K, Dong X, Tsuda M.

J Allergy Clin Immunol. 2019 Mar;143(3):1252-1254.e8. doi: 10.1016/j.jaci.2018.10.053. Epub 2018 Nov 17. No abstract available.


Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy.

Iizuka N, Morita A, Kawano C, Mori A, Sakamoto K, Kuroyama M, Ishii K, Nakahara T.

J Pharmacol Sci. 2018 Nov;138(3):203-208. doi: 10.1016/j.jphs.2018.10.004. Epub 2018 Oct 14.


Reply to the letter to the editor.

Koga Y, Fujita M, Yagi T, Todani M, Nakahara T, Kawamura Y, Kaneda K, Oda Y, Tsuruta R.

J Crit Care. 2019 Feb;49:193-194. doi: 10.1016/j.jcrc.2018.10.020. Epub 2018 Oct 29. No abstract available.


Dental pulp cell bank as a possible future source of individual hepatocytes.

Ohkoshi S, Hirono H, Nakahara T, Ishikawa H.

World J Hepatol. 2018 Oct 27;10(10):702-707. doi: 10.4254/wjh.v10.i10.702. Review.


The impact of interferon-free direct-acting antivirals on clinical outcome after curative treatment for hepatitis C virus-associated hepatocellular carcinoma: Comparison with interferon-based therapy.

Nagaoki Y, Imamura M, Nishida Y, Daijo K, Teraoka Y, Honda F, Nakamura Y, Morio K, Fujino H, Nakahara T, Kawaoka T, Tsuge M, Hiramatsu A, Kawakami Y, Miki D, Hiyama Y, Ochi H, Chayama K, Aikata H.

J Med Virol. 2019 Apr;91(4):650-658. doi: 10.1002/jmv.25352. Epub 2018 Nov 19.


Thrombocytopenia in a psoriatic patient sequentially treated with adalimumab, secukinumab and ustekinumab.

Nakahara T, Konishi S, Yasukochi Y, Esaki H, Tsuji G, Kido-Nakahara M, Furue M.

J Dermatol. 2019 May;46(5):e157-e158. doi: 10.1111/1346-8138.14681. Epub 2018 Oct 24. No abstract available.


Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures.

Osawa M, Imamura M, Teraoka Y, Uchida T, Morio K, Fujino H, Nakahara T, Ono A, Murakami E, Kawaoka T, Miki D, Tsuge M, Hiramatsu A, Aikata H, Hayes CN, Chayama K; Hiroshima Liver Study Group.

J Gastroenterol. 2019 Mar;54(3):291-296. doi: 10.1007/s00535-018-1520-9. Epub 2018 Oct 17.


Pruritus in Chronic Liver Disease: A Questionnaire Survey on 216 Patients.

Kido-Nakahara M, Nakahara T, Furusyo N, Shimoda S, Kotoh K, Kato M, Hayashi J, Koyanagi T, Furue M.

Acta Derm Venereol. 2019 Feb 1;99(2):220-221. doi: 10.2340/00015555-3064. No abstract available.


NaF uptake in unstable plaque: what does fluoride uptake mean?

Nakahara T, Narula J, Strauss HW.

Eur J Nucl Med Mol Imaging. 2018 Dec;45(13):2250-2252. doi: 10.1007/s00259-018-4177-y. No abstract available.


Anti-cataract Effect of Resveratrol in High-Glucose-Treated Streptozotocin-Induced Diabetic Rats.

Higashi Y, Higashi K, Mori A, Sakamoto K, Ishii K, Nakahara T.

Biol Pharm Bull. 2018;41(10):1586-1592. doi: 10.1248/bpb.b18-00328.


Optimization and validation of an SBSE-HPLC-FD method using laboratory-made stir bars for fluoxetine determination in human plasma.

Marques LA, Nakahara TT, Bervelieri Madeira T, Bortholazzi Almeida M, Maffei Monteiro A, de Almeida Silva M, Carrilho E, Piccoli de Melo LG, Nixdorf SL.

Biomed Chromatogr. 2019 Jan;33(1):e4398. doi: 10.1002/bmc.4398. Epub 2018 Oct 23.


Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes.

Tsuge M, Hiraga N, Zhang Y, Yamashita M, Sato O, Oka N, Shiraishi K, Izaki Y, Makokha GN, Uchida T, Kurihara M, Nomura M, Tsushima K, Nakahara T, Murakami E, Abe-Chayama H, Kawaoka T, Miki D, Imamura M, Kawakami Y, Aikata H, Ochi H, Hayes CN, Fujita T, Chayama K.

Virology. 2018 Dec;525:48-61. doi: 10.1016/j.virol.2018.08.020. Epub 2018 Sep 18.


Crystallization granuloma by nifekalant hydrochloride infusion.

Ichiki T, Wada M, Yasukouchi Y, Nakahara T, Mitoma C, Uchi H, Nishizaki A, Mukai Y, Furue M.

Geriatr Gerontol Int. 2018 Jul;18(7):1133-1134. doi: 10.1111/ggi.13329. No abstract available.


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