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Items: 1 to 50 of 3480

1.

Comprehensive analysis of indels in whole-genome microsatellite regions and microsatellite instability across 21 cancer types.

Fujimoto A, Fujita M, Hasegawa T, Wong JH, Maejima K, Oku-Sasaki A, Nakano K, Shiraishi Y, Miyano S, Yamamoto G, Akagi K, Imoto S, Nakagawa H.

Genome Res. 2020 Mar 24. doi: 10.1101/gr.255026.119. [Epub ahead of print]

2.

Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples.

Sakamoto S, Komatsu T, Watanabe R, Zhang Y, Inoue T, Kawaguchi M, Nakagawa H, Ueno T, Okusaka T, Honda K, Noji H, Urano Y.

Sci Adv. 2020 Mar 11;6(11):eaay0888. doi: 10.1126/sciadv.aay0888. eCollection 2020 Mar.

3.

Food Sources of Dietary Potassium in the Adult Japanese Population: The International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP).

Okuda N, Okayama A, Miura K, Yoshita K, Miyagawa N, Saitoh S, Nakagawa H, Sakata K, Chan Q, Elliott P, Ueshima H, Stamler J.

Nutrients. 2020 Mar 17;12(3). pii: E787. doi: 10.3390/nu12030787.

4.

Refractoriness to subcutaneous implantable cardioverter defibrillator after frequent therapies for ventricular fibrillation storms in a Brugada syndrome case.

Nakao Y, Suenari K, Yamashiro K, Nakagawa H, Shiode N.

BMC Cardiovasc Disord. 2020 Mar 13;20(1):134. doi: 10.1186/s12872-020-01405-4.

5.

L1CAM Is a Marker for Enriching Corticospinal Motor Neurons in the Developing Brain.

Samata B, Takaichi R, Ishii Y, Fukushima K, Nakagawa H, Ono Y, Takahashi J.

Front Cell Neurosci. 2020 Feb 19;14:31. doi: 10.3389/fncel.2020.00031. eCollection 2020.

6.

Identification of Potent In Vivo Autotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain.

Kawaguchi M, Okabe T, Okudaira S, Hama K, Kano K, Nishimasu H, Nakagawa H, Ishitani R, Kojima H, Nureki O, Aoki J, Nagano T.

J Med Chem. 2020 Mar 26;63(6):3188-3204. doi: 10.1021/acs.jmedchem.9b01967. Epub 2020 Mar 13.

PMID:
32134652
7.

Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations.

Fujita M, Yamaguchi R, Hasegawa T, Shimada S, Arihiro K, Hayashi S, Maejima K, Nakano K, Fujimoto A, Ono A, Aikata H, Ueno M, Hayami S, Tanaka H, Miyano S, Yamaue H, Chayama K, Kakimi K, Tanaka S, Imoto S, Nakagawa H.

EBioMedicine. 2020 Mar;53:102659. doi: 10.1016/j.ebiom.2020.102659. Epub 2020 Feb 26.

8.

Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids.

Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB.

Curr Protoc Stem Cell Biol. 2020 Mar;52(1):e106. doi: 10.1002/cpsc.106.

PMID:
32105412
9.

Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer.

Ha K, Fujita M, Karlić R, Yang S, Xue R, Zhang C, Bai F, Zhang N, Hoshida Y, Polak P, Nakagawa H, Kim HG, Lee H.

Heliyon. 2020 Feb 11;6(2):e03350. doi: 10.1016/j.heliyon.2020.e03350. eCollection 2020 Feb.

10.

Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma.

Hirata M, Asano N, Katayama K, Yoshida A, Tsuda Y, Sekimizu M, Mitani S, Kobayashi E, Komiyama M, Fujimoto H, Goto T, Iwamoto Y, Naka N, Iwata S, Nishida Y, Hiruma T, Hiraga H, Kawano H, Motoi T, Oda Y, Matsubara D, Fujita M, Shibata T, Nakagawa H, Nakayama R, Kondo T, Imoto S, Miyano S, Kawai A, Yamaguchi R, Ichikawa H, Matsuda K.

Nat Commun. 2020 Feb 19;11(1):1024. doi: 10.1038/s41467-020-14680-8.

11.

[Comparison of Detectability for the New Image Processing and Conventional Image Processing by ROC Analysis: A Phantom Study of Chest Radiography].

Kiriki M, Osaki T, Nakagawa H, Nakamura M, Fujikawa K, Nakamura K, Kikuchi K, Hama Y, Hagiwara Y, Kotoura N.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2020;76(2):203-209. doi: 10.6009/jjrt.2020_JSRT_76.2.203. Japanese.

12.

Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers.

Yuan Y, Ju YS, Kim Y, Li J, Wang Y, Yoon CJ, Yang Y, Martincorena I, Creighton CJ, Weinstein JN, Xu Y, Han L, Kim HL, Nakagawa H, Park K, Campbell PJ, Liang H; PCAWG Consortium.

Nat Genet. 2020 Feb 11. doi: 10.1038/s41588-020-0587-4. [Epub ahead of print]

PMID:
32047324
13.

GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.

Hata M, Kinoshita H, Hayakawa Y, Konishi M, Tsuboi M, Oya Y, Kurokawa K, Hayata Y, Nakagawa H, Tateishi K, Fujiwara H, Hirata Y, Worthley DL, Muranishi Y, Furukawa T, Kon S, Tomita H, Wang TC, Koike K.

Gastroenterology. 2020 Feb 4. pii: S0016-5085(20)30158-X. doi: 10.1053/j.gastro.2020.01.046. [Epub ahead of print]

PMID:
32032583
14.

Delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with moderate to severe atopic dermatitis: A phase 3, randomized, double-blind, vehicle-controlled study and an open-label, long-term extension study.

Nakagawa H, Nemoto O, Igarashi A, Saeki H, Kaino H, Nagata T.

J Am Acad Dermatol. 2020 Apr;82(4):823-831. doi: 10.1016/j.jaad.2019.12.015. Epub 2020 Feb 3.

15.

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, Shuai S, Lanzós A, Herrmann C, Maruvka YE, Shen C, Amin SB, Bandopadhayay P, Bertl J, Boroevich KA, Busanovich J, Carlevaro-Fita J, Chakravarty D, Chan CWY, Craft D, Dhingra P, Diamanti K, Fonseca NA, Gonzalez-Perez A, Guo Q, Hamilton MP, Haradhvala NJ, Hong C, Isaev K, Johnson TA, Juul M, Kahles A, Kahraman A, Kim Y, Komorowski J, Kumar K, Kumar S, Lee D, Lehmann KV, Li Y, Liu EM, Lochovsky L, Park K, Pich O, Roberts ND, Saksena G, Schumacher SE, Sidiropoulos N, Sieverling L, Sinnott-Armstrong N, Stewart C, Tamborero D, Tubio JMC, Umer HM, Uusküla-Reimand L, Wadelius C, Wadi L, Yao X, Zhang CZ, Zhang J, Haber JE, Hobolth A, Imielinski M, Kellis M, Lawrence MS, von Mering C, Nakagawa H, Raphael BJ, Rubin MA, Sander C, Stein LD, Stuart JM, Tsunoda T, Wheeler DA, Johnson R, Reimand J, Gerstein M, Khurana E, Campbell PJ, López-Bigas N; PCAWG Drivers and Functional Interpretation Working Group; PCAWG Structural Variation Working Group, Weischenfeldt J, Beroukhim R, Martincorena I, Pedersen JS, Getz G; PCAWG Consortium.

Nature. 2020 Feb;578(7793):102-111. doi: 10.1038/s41586-020-1965-x. Epub 2020 Feb 5.

16.

Comprehensive molecular characterization of mitochondrial genomes in human cancers.

Yuan Y, Ju YS, Kim Y, Li J, Wang Y, Yoon CJ, Yang Y, Martincorena I, Creighton CJ, Weinstein JN, Xu Y, Han L, Kim HL, Nakagawa H, Park K, Campbell PJ, Liang H; PCAWG Consortium.

Nat Genet. 2020 Mar;52(3):342-352. doi: 10.1038/s41588-019-0557-x. Epub 2020 Feb 5. Erratum in: Nat Genet. 2020 Feb 11;:.

17.

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.

Zhang Y, Chen F, Fonseca NA, He Y, Fujita M, Nakagawa H, Zhang Z, Brazma A; PCAWG Transcriptome Working Group; PCAWG Structural Variation Working Group, Creighton CJ; PCAWG Consortium.

Nat Commun. 2020 Feb 5;11(1):736. doi: 10.1038/s41467-019-13885-w.

18.

Effect of heat acclimation on anxiety-like behavior of rats in an open field.

Nakagawa H, Matsunaga D, Ishiwata T.

J Therm Biol. 2020 Jan;87:102458. doi: 10.1016/j.jtherbio.2019.102458. Epub 2019 Dec 9.

PMID:
31999599
19.

How can we derive hydration water dynamics with incoherent neutron scattering and molecular dynamics simulation?

Nakagawa H, Kataoka M.

Biophys Physicobiol. 2019 Nov 29;16:213-219. doi: 10.2142/biophysico.16.0_213. eCollection 2019.

20.

The utility of serial procalcitonin measurements in addition to pneumonia severity scores in hospitalised community-acquired pneumonia: A multicentre, prospective study.

Ito A, Ito I, Inoue D, Marumo S, Ueda T, Nakagawa H, Taki M, Nakagawa A, Tatsumi S, Nishimura T, Shiota T, Ishida T.

Int J Infect Dis. 2020 Mar;92:228-233. doi: 10.1016/j.ijid.2020.01.018. Epub 2020 Jan 22.

21.

Efficient synthesis of tert-butyl 3-cyano-3-cyclopropyl-2-oxopyrrolidine-4-carboxylates: Highly functionalized 2-pyrrolidinone enabling access to novel macrocyclic Tyk2 inhibitors.

Sasaki Y, Tokuhara H, Ohba Y, Okabe A, Nakayama M, Nakagawa H, Skene R, Hoffman I, Zou H, Yoshida M.

Bioorg Med Chem Lett. 2020 Mar 1;30(5):126963. doi: 10.1016/j.bmcl.2020.126963. Epub 2020 Jan 13.

PMID:
31980341
22.

Rigidity of protein structure revealed by incoherent neutron scattering.

Nakagawa H, Kataoka M.

Biochim Biophys Acta Gen Subj. 2020 Apr;1864(4):129536. doi: 10.1016/j.bbagen.2020.129536. Epub 2020 Jan 17.

PMID:
31958544
23.

Outcomes of patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study.

Otaki F, Ma GK, Krigel A, Dierkhising RA, Lewis JT, Blevins CH, Gopalakrishnan NP, Ravindran A, Johnson ML, Leggett CL, Wigle D, Wang KK, Falk GW, Abrams JA, Nakagawa H, Rustgi AK, Wang TC, Lightdale CJ, Ginsberg GG, Iyer PG.

Gastrointest Endosc. 2020 Jan 14. pii: S0016-5107(20)30035-3. doi: 10.1016/j.gie.2020.01.013. [Epub ahead of print]

PMID:
31953189
24.

Japanese guidance for use of biologics for psoriasis (the 2019 version).

Saeki H, Terui T, Morita A, Sano S, Imafuku S, Asahina A, Komine M, Etoh T, Igarashi A, Torii H, Abe M, Nakagawa H, Watanabe A, Yotsuyanagi H, Ohtsuki M; Biologics Review Committee of the Japanese Dermatological Association for Psoriasis: Chair: Mamitaro Ohtsuki.

J Dermatol. 2020 Mar;47(3):201-222. doi: 10.1111/1346-8138.15196. Epub 2020 Jan 8.

PMID:
31916326
25.

Incidence and Clinical Significance of 30-Day and 90-Day Rehospitalization for Heart Failure Among Patients With Acute Decompensated Heart Failure in Japan - From the NARA-HF Study.

Ishihara S, Kawakami R, Nogi M, Hirai K, Hashimoto Y, Nakada Y, Nakagawa H, Ueda T, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Saito Y.

Circ J. 2020 Jan 24;84(2):194-202. doi: 10.1253/circj.CJ-19-0620. Epub 2019 Dec 26.

26.

Lack of association of TNFA, TNFRSF1B and TNFAIP3 gene polymorphisms with response to anti-tumor necrosis factor therapy in Japanese patients with psoriasis.

Ito M, Hirota T, Momose M, Ito T, Umezawa Y, Fukuchi O, Asahina A, Nakagawa H, Tamari M, Saeki H.

J Dermatol. 2020 Apr;47(4):e110-e111. doi: 10.1111/1346-8138.15200. Epub 2019 Dec 23. No abstract available.

PMID:
31872456
27.

Risk Factors for Major Bleeding and Clinically Relevant Non-major Bleeding in Japanese Patients Treated with Edoxaban.

Takase T, Ikesue H, Nakagawa H, Kinoshita M, Muroi N, Kitai T, Furukawa Y, Hashida T.

Biol Pharm Bull. 2020 Mar 1;43(3):458-462. doi: 10.1248/bpb.b19-00799. Epub 2019 Dec 18.

28.

In Vitro Differentiation of Chicken Astrocytes: Growth, Morphology, and Protein Expression of Astrocytes in Primary Cultures.

Tsukuda S, Tamura A, Matsumoto K, Fujita Y, Nakata S, Kaneko T, Nakayama A, Nakagawa H, Terasaki AG.

Zoolog Sci. 2019 Dec 9;36(6):458-467. doi: 10.2108/zs180102.

PMID:
31833316
29.

Integrated exome and RNA sequencing of dedifferentiated liposarcoma.

Hirata M, Asano N, Katayama K, Yoshida A, Tsuda Y, Sekimizu M, Mitani S, Kobayashi E, Komiyama M, Fujimoto H, Goto T, Iwamoto Y, Naka N, Iwata S, Nishida Y, Hiruma T, Hiraga H, Kawano H, Motoi T, Oda Y, Matsubara D, Fujita M, Shibata T, Nakagawa H, Nakayama R, Kondo T, Imoto S, Miyano S, Kawai A, Yamaguchi R, Ichikawa H, Matsuda K.

Nat Commun. 2019 Dec 12;10(1):5683. doi: 10.1038/s41467-019-13286-z. Erratum in: Nat Commun. 2020 Feb 19;11(1):1024.

30.

Effects of sorbitol and lactate on erythropoietin production in HepG2 cells.

Nishimura K, Katsuyama H, Ohishi M, Hirabayashi A, Matsuda K, Nakagawa H.

Biochem Biophys Res Commun. 2020 Feb 26;523(1):54-59. doi: 10.1016/j.bbrc.2019.12.001. Epub 2019 Dec 9.

PMID:
31831169
31.

Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation.

Fujiwara H, Tateishi K, Misumi K, Hayashi A, Igarashi K, Kato H, Nakatsuka T, Suzuki N, Yamamoto K, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Ijichi H, Kogure H, Nakai Y, Isayama H, Hasegawa K, Fukayama M, Soga T, Koike K.

Sci Rep. 2019 Dec 11;9(1):18859. doi: 10.1038/s41598-019-55211-w.

32.

Long-term safety and efficacy of delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with atopic dermatitis.

Nakagawa H, Nemoto O, Igarashi A, Saeki H, Murata R, Kaino H, Nagata T.

J Dermatol. 2020 Feb;47(2):114-120. doi: 10.1111/1346-8138.15173. Epub 2019 Dec 9.

33.

Correction: Quantitative CT analysis of honeycombing area predicts mortality in idiopathic pulmonary fibrosis with definite usual interstitial pneumonia pattern: A retrospective cohort study.

Nakagawa H, Ogawa E, Fukunaga K, Kinose D, Yamaguchi M, Nagao T, Tanaka-Mizuno S, Nakano Y.

PLoS One. 2019 Dec 2;14(12):e0226214. doi: 10.1371/journal.pone.0226214. eCollection 2019.

34.

Plasma quercetin metabolites are affected by intestinal microbiota of human microbiota-associated mice fed with a quercetin-containing diet.

Tamura M, Nakagawa H, Hori S, Suzuki T, Hirayama K.

J Clin Biochem Nutr. 2019 Nov;65(3):232-239. doi: 10.3164/jcbn.19-45. Epub 2019 Oct 10.

35.
36.

Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus.

Bailey DD, Zhang Y, van Soldt BJ, Jiang M, Suresh S, Nakagawa H, Rustgi AK, Aceves SS, Cardoso WV, Que J.

Development. 2019 Dec 4;146(23). pii: dev178855. doi: 10.1242/dev.178855.

PMID:
31748205
37.

Lymphoid Papillary Hyperplasia Arising from the Upper Portion of the Left Palatine Tonsil: A Case Report and Literature Review.

Yorita K, Nakagawa H, Miyazaki K, Ishitani Y, Arisawa Y.

Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):835-838. doi: 10.1007/s12070-019-01668-0. Epub 2019 May 4.

PMID:
31742076
38.

Molecular Basis of Water Activity in Glycerol-Water Mixtures.

Nakagawa H, Oyama T.

Front Chem. 2019 Nov 1;7:731. doi: 10.3389/fchem.2019.00731. eCollection 2019.

39.

Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor.

Wang L, Shen E, Luo L, Rabe H, Wang Q, Yin J, Yang X, Liu W, Sido JM, Nakagawa H, Ao L, Kim HJ, Cantor H, Leavenworth JW.

Cell Rep. 2019 Nov 12;29(7):1848-1861.e6. doi: 10.1016/j.celrep.2019.10.012.

40.

Utility of hepatic vein waveform and transient elastography in patients with Budd-Chiari syndrome who require angioplasty: Two case reports.

Nakatsuka T, Soroida Y, Nakagawa H, Okura N, Sato J, Akahane M, Sato M, Yatomi Y, Abe O, Tateishi R, Koike K.

Medicine (Baltimore). 2019 Nov;98(45):e17877. doi: 10.1097/MD.0000000000017877.

41.

Broad-Spectrum Disease Resistance Conferred by the Overexpression of Rice RLCK BSR1 Results from an Enhanced Immune Response to Multiple MAMPs.

Kanda Y, Nakagawa H, Nishizawa Y, Kamakura T, Mori M.

Int J Mol Sci. 2019 Nov 6;20(22). pii: E5523. doi: 10.3390/ijms20225523.

42.

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition.

Guha M, Srinivasan S, Sheehan MM, Kijima T, Ruthel G, Whelan K, Tanaka K, Klein-Szanto A, Chandramouleeswaran PM, Nakagawa H, Avadhani NG.

Oncotarget. 2019 Oct 22;10(58):6245-6259. doi: 10.18632/oncotarget.27264. eCollection 2019 Oct 22.

43.

Whole genome sequencing data of Oryza sativa L. cv. Takanari.

Kajiya-Kanegae H, Yabe S, Yoshida H, Ebana K, Yamasaki M, Nakagawa H, Iwata H.

Data Brief. 2019 Sep 20;27:104546. doi: 10.1016/j.dib.2019.104546. eCollection 2019 Dec.

44.

AST-120, an Oral Carbon Absorbent, Protects against the Progression of Atherosclerosis in a Mouse Chronic Renal Failure Model by Preserving sFlt-1 Expression Levels.

Nakada Y, Onoue K, Nakano T, Ishihara S, Kumazawa T, Nakagawa H, Ueda T, Nishida T, Soeda T, Okayama S, Watanabe M, Kawakami R, Saito Y.

Sci Rep. 2019 Oct 30;9(1):15571. doi: 10.1038/s41598-019-51292-9.

45.

Design and Synthesis of Conformationally Constrained RORγt Inverse Agonists.

Sato A, Fukase Y, Kono M, Ochida A, Oda T, Sasaki Y, Ishii N, Tomata Y, Fukumoto S, Imai YN, Uga K, Shibata A, Yamasaki M, Nakagawa H, Shirasaki M, Skene R, Hoffman I, Sang BC, Snell G, Shirai J, Yamamoto S.

ChemMedChem. 2019 Nov 20;14(22):1917-1932. doi: 10.1002/cmdc.201900416. Epub 2019 Nov 5.

PMID:
31659845
46.

eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA.

Mizuno K, Akamatsu S, Sumiyoshi T, Wong JH, Fujita M, Maejima K, Nakano K, Ono A, Aikata H, Ueno M, Hayami S, Yamaue H, Chayama K, Inoue T, Ogawa O, Nakagawa H, Fujimoto A.

Sci Rep. 2019 Oct 22;9(1):15017. doi: 10.1038/s41598-019-51459-4.

47.

Relationship between cancer mortality and environmental cadmium exposure in the general Japanese population in cadmium non-polluted areas.

Watanabe Y, Nogawa K, Nishijo M, Sakurai M, Ishizaki M, Morikawa Y, Kido T, Nakagawa H, Suwazono Y.

Int J Hyg Environ Health. 2020 Jan;223(1):65-70. doi: 10.1016/j.ijheh.2019.10.005. Epub 2019 Oct 18.

PMID:
31635989
48.

Ratiometric assay of CARM1 activity using a FRET-based fluorescent probe.

Ohta Y, Wakita H, Kawaguchi M, Ieda N, Osada S, Nakagawa H.

Bioorg Med Chem Lett. 2019 Nov 15;29(22):126728. doi: 10.1016/j.bmcl.2019.126728. Epub 2019 Oct 4.

PMID:
31607607
49.

Effect of the number of dose adjustment factors on bleeding risk in patients receiving 30 mg/day edoxaban.

Takase T, Ikesue H, Nakagawa H, Kinoshita M, Muroi N, Kitai T, Furukawa Y, Hashida T.

J Clin Pharm Ther. 2020 Apr;45(2):298-302. doi: 10.1111/jcpt.13065. Epub 2019 Oct 11.

50.

Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients.

Enooku K, Tsutsumi T, Kondo M, Fujiwara N, Sasako T, Shibahara J, Kado A, Okushin K, Fujinaga H, Nakagomi R, Minami T, Sato M, Uchino K, Nakagawa H, Kondo Y, Asaoka Y, Tateishi R, Ueki K, Ikeda H, Yoshida H, Moriya K, Yotsuyanagi H, Kadowaki T, Koike K.

J Gastroenterol. 2020 Feb;55(2):227-243. doi: 10.1007/s00535-019-01633-2. Epub 2019 Oct 10.

PMID:
31602526

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