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Items: 1 to 50 of 244

1.

Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis.

Ju N, Shimamura M, Hayashi H, Ikeda Y, Yoshida S, Nakamura A, Morishita R, Rakugi H, Nakagami H.

Sci Rep. 2019 Oct 28;9(1):15434. doi: 10.1038/s41598-019-51681-0.

2.

Pathophysiology of cardiovascular disease in diabetes mellitus.

Rodriguez-Araujo G, Nakagami H.

Cardiovasc Endocrinol Metab. 2018 Feb 14;7(1):4-9. doi: 10.1097/XCE.0000000000000141. eCollection 2018 Mar. Review.

3.

Isolation of natural fungal pathogens from Marchantia polymorpha reveals antagonism between salicylic acid and jasmonate during liverwort-fungus interactions.

Matsui H, Iwakawa H, Hyon GS, Yotsui I, Katou S, Monte I, Nishihama R, Franzen R, Solano R, Nakagami H.

Plant Cell Physiol. 2019 Sep 27. pii: pcz187. doi: 10.1093/pcp/pcz187. [Epub ahead of print]

PMID:
31560390
4.

The Arabidopsis Cdk1/Cdk2 homolog CDKA;1 controls chromosome axis assembly during plant meiosis.

Yang C, Sofroni K, Wijnker E, Hamamura Y, Carstens L, Harashima H, Stolze SC, Vezon D, Chelysheva L, Orban-Nemeth Z, Pochon G, Nakagami H, Schlögelhofer P, Grelon M, Schnittger A.

EMBO J. 2019 Sep 26:e101625. doi: 10.15252/embj.2019101625. [Epub ahead of print]

PMID:
31556459
5.

Comparative phosphoproteomic analysis reveals a decay of ABA signaling in barley embryos during after-ripening.

Ishikawa S, Barrero JM, Takahashi F, Nakagami H, Peck SC, Gubler F, Shinozaki K, Umezawa T.

Plant Cell Physiol. 2019 Aug 21. pii: pcz163. doi: 10.1093/pcp/pcz163. [Epub ahead of print]

PMID:
31435655
6.

Shotgun Proteomic Analysis Highlights the Roles of Long-Lived mRNAs and De Novo Transcribed mRNAs in Rice Seeds upon Imbibition.

Sano N, Takebayashi Y, To A, Mhiri C, Rajjou LC, Nakagami H, Kanekatsu M.

Plant Cell Physiol. 2019 Nov 1;60(11):2584-2596. doi: 10.1093/pcp/pcz152.

PMID:
31373371
7.

Direct evidence on the efficacy of GnRH agonist in recurrent steroid cell tumor-not otherwise specified.

Nakasone T, Nakamoto T, Matsuzaki A, Nakagami H, Aoki Y.

Gynecol Oncol Rep. 2019 Jul 16;29:73-75. doi: 10.1016/j.gore.2019.07.006. eCollection 2019 Aug.

8.

Conserved Biochemical Defenses Underpin Host Responses to Oomycete Infection in an Early-Divergent Land Plant Lineage.

Carella P, Gogleva A, Hoey DJ, Bridgen AJ, Stolze SC, Nakagami H, Schornack S.

Curr Biol. 2019 Jul 22;29(14):2282-2294.e5. doi: 10.1016/j.cub.2019.05.078. Epub 2019 Jul 11.

PMID:
31303485
9.

Gene modification by fast-track recombineering for cellular localization and isolation of components of plant protein complexes.

Hu Z, Ghosh A, Stolze SC, Horváth M, Bai B, Schaefer S, Zündorf S, Liu S, Harzen A, Hajheidari M, Sarnowski TJ, Nakagami H, Koncz Z, Koncz C.

Plant J. 2019 Oct;100(2):411-429. doi: 10.1111/tpj.14450. Epub 2019 Jul 26.

PMID:
31276249
10.

Temporal and spatial profile of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in ischemic stroke in mice.

Kawano T, Shimamura M, Nakagami H, Kanki H, Sasaki T, Mochizuki H.

PLoS One. 2019 May 2;14(5):e0215482. doi: 10.1371/journal.pone.0215482. eCollection 2019.

11.

SWITCH 1/DYAD is a WINGS APART-LIKE antagonist that maintains sister chromatid cohesion in meiosis.

Yang C, Hamamura Y, Sofroni K, Böwer F, Stolze SC, Nakagami H, Schnittger A.

Nat Commun. 2019 Apr 15;10(1):1755. doi: 10.1038/s41467-019-09759-w.

12.

A vaccine targeting blood clot formation: what is the potential?

Shimamura M, Nakagami H.

Expert Rev Vaccines. 2019 May;18(5):419-421. doi: 10.1080/14760584.2019.1588114. Epub 2019 Mar 20. No abstract available.

PMID:
30884991
13.

Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity.

Yoshida Y, Shimizu I, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Wakasugi T, Nakao M, Nakagami H, Morishita R, Minamino T.

Sci Rep. 2019 Mar 7;9(1):3858. doi: 10.1038/s41598-019-40325-y.

14.

Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein-treated endothelial progenitor cells: a novel index for the prediction of HDL functionality.

Shih CM, Lin FY, Yeh JS, Lin YW, Loh SH, Tsao NW, Nakagami H, Morishita R, Sawamura T, Li CY, Lin CY, Huang CY.

Transl Res. 2019 Mar;205:17-32. doi: 10.1016/j.trsl.2018.09.005. Epub 2018 Oct 9.

PMID:
30720435
15.

Algal Protein Kinase, Triacylglycerol Accumulation Regulator 1, Modulates Cell Viability and Gametogenesis in Carbon/Nitrogen-Imbalanced Conditions.

Shinkawa H, Kajikawa M, Nomura Y, Ogura M, Sawaragi Y, Yamano T, Nakagami H, Sugiyama N, Ishihama Y, Kanesaki Y, Yoshikawa H, Fukuzawa H.

Plant Cell Physiol. 2019 Apr 1;60(4):916-930. doi: 10.1093/pcp/pcz010.

PMID:
30668822
16.

Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice.

Kawano T, Shimamura M, Nakagami H, Iso T, Koriyama H, Takeda S, Baba K, Sasaki T, Sakaguchi M, Morishita R, Mochizuki H.

Hypertension. 2018 Dec;72(6):1355-1364. doi: 10.1161/HYPERTENSIONAHA.118.11316.

PMID:
30571223
17.

Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.

Imaizumi Y, Takami Y, Yamamoto K, Nagasawa M, Nozato Y, Nozato S, Takeshita H, Wang C, Yokoyama S, Hayashi H, Hongyo K, Akasaka H, Takeya Y, Sugimoto K, Nakagami H, Rakugi H.

Biochem Biophys Res Commun. 2019 Jan 22;508(4):1168-1174. doi: 10.1016/j.bbrc.2018.12.025. Epub 2018 Dec 13.

PMID:
30554661
18.

A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis.

Uemura T, Nakano RT, Takagi J, Wang Y, Kramer K, Finkemeier I, Nakagami H, Tsuda K, Ueda T, Schulze-Lefert P, Nakano A.

Plant Physiol. 2019 Feb;179(2):519-532. doi: 10.1104/pp.18.01228. Epub 2018 Dec 13.

19.

Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke.

Shimamura M, Nakagami H, Shimizu H, Mukai H, Watanabe R, Okuzono T, Kawano T, Ikeda Y, Hayashi H, Yoshida S, Ju N, Mochizuki H, Morishita R.

Sci Rep. 2018 Dec 11;8(1):17770. doi: 10.1038/s41598-018-35898-z.

20.

Recent Advances in Therapeutic Vaccines to Treat Hypertension.

Nakagami H, Morishita R.

Hypertension. 2018 Nov;72(5):1031-1036. doi: 10.1161/HYPERTENSIONAHA.118.11084. Review. No abstract available.

PMID:
30354822
21.

Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice.

Takeshita H, Yamamoto K, Nozato S, Takeda M, Fukada SI, Inagaki T, Tsuchimochi H, Shirai M, Nozato Y, Fujimoto T, Imaizumi Y, Yokoyama S, Nagasawa M, Hamano G, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Takeda S, Takahashi T, Akasaka H, Itoh N, Takami Y, Takeya Y, Sugimoto K, Nakagami H, Rakugi H.

J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):975-986. doi: 10.1002/jcsm.12334. Epub 2018 Sep 11.

22.

Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice.

Shimamura M, Nakagami H, Shimizu H, Wakayama K, Kawano T, Ikeda Y, Hayashi H, Yoshida S, Mochizuki H, Morishita R.

Biomed Res Int. 2018 Jul 30;2018:4637084. doi: 10.1155/2018/4637084. eCollection 2018.

23.

SELENOPROTEIN O is a chloroplast protein involved in ROS scavenging and its absence increases dehydration tolerance in Arabidopsis thaliana.

Fichman Y, Koncz Z, Reznik N, Miller G, Szabados L, Kramer K, Nakagami H, Fromm H, Koncz C, Zilberstein A.

Plant Sci. 2018 May;270:278-291. doi: 10.1016/j.plantsci.2018.02.023. Epub 2018 Mar 3.

PMID:
29576081
24.

Therapeutic Vaccines for Hypertension: a New Option for Clinical Practice.

Nakagami H, Morishita R.

Curr Hypertens Rep. 2018 Mar 19;20(3):22. doi: 10.1007/s11906-018-0820-z. Review.

PMID:
29556794
25.

Physician-initiated clinical study of limb ulcers treated with a functional peptide, SR-0379: from discovery to a randomized, double-blind, placebo-controlled trial.

Nakagami H, Sugimoto K, Ishikawa T, Fujimoto T, Yamaoka T, Hayashi M, Kiyohara E, Ando H, Terabe Y, Takami Y, Yamamoto K, Takeya Y, Takemoto M, Koshizaka M, Ebihara T, Nakamura A, Nishikawa M, Yao XJ, Hanaoka H, Katayama I, Yokote K, Rakugi H.

NPJ Aging Mech Dis. 2018 Feb 13;4:2. doi: 10.1038/s41514-018-0021-7. eCollection 2018.

26.

Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice.

Kawakami R, Nozato Y, Nakagami H, Ikeda Y, Shimamura M, Yoshida S, Sun J, Kawano T, Takami Y, Noma T, Rakugi H, Minamino T, Morishita R.

PLoS One. 2018 Feb 13;13(2):e0191895. doi: 10.1371/journal.pone.0191895. eCollection 2018.

27.

Stable Accumulation of Photosystem II Requires ONE-HELIX PROTEIN1 (OHP1) of the Light Harvesting-Like Family.

Myouga F, Takahashi K, Tanaka R, Nagata N, Kiss AZ, Funk C, Nomura Y, Nakagami H, Jansson S, Shinozaki K.

Plant Physiol. 2018 Mar;176(3):2277-2291. doi: 10.1104/pp.17.01782. Epub 2018 Feb 1.

28.

Comparative analysis of plant isochorismate synthases reveals structural mechanisms underlying their distinct biochemical properties.

Yokoo S, Inoue S, Suzuki N, Amakawa N, Matsui H, Nakagami H, Takahashi A, Arai R, Katou S.

Biosci Rep. 2018 Mar 9;38(2). pii: BSR20171457. doi: 10.1042/BSR20171457. Print 2018 Apr 27.

29.

Blue light-excited LOV1 and LOV2 domains cooperatively regulate the kinase activity of full-length phototropin2 from Arabidopsis.

Oide M, Okajima K, Nakagami H, Kato T, Sekiguchi Y, Oroguchi T, Hikima T, Yamamoto M, Nakasako M.

J Biol Chem. 2018 Jan 19;293(3):963-972. doi: 10.1074/jbc.RA117.000324. Epub 2017 Dec 1.

30.

Association between renin-angiotensin-aldosterone system blockade and future osteoporotic fracture risk in hypertensive population: A population-based cohort study in Taiwan.

Chen CI, Yeh JS, Tsao NW, Lin FY, Shih CM, Chiang KH, Kao YT, Fang YA, Tsai LW, Liu WC, Nakagami H, Morishita R, Kuo YJ, Huang CY.

Medicine (Baltimore). 2017 Nov;96(46):e8331. doi: 10.1097/MD.0000000000008331.

31.

The GYF domain protein PSIG1 dampens the induction of cell death during plant-pathogen interactions.

Matsui H, Nomura Y, Egusa M, Hamada T, Hyon GS, Kaminaka H, Watanabe Y, Ueda T, Trujillo M, Shirasu K, Nakagami H.

PLoS Genet. 2017 Oct 26;13(10):e1007037. doi: 10.1371/journal.pgen.1007037. eCollection 2017 Oct.

32.

Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome.

Bowman JL, Kohchi T, Yamato KT, Jenkins J, Shu S, Ishizaki K, Yamaoka S, Nishihama R, Nakamura Y, Berger F, Adam C, Aki SS, Althoff F, Araki T, Arteaga-Vazquez MA, Balasubrmanian S, Barry K, Bauer D, Boehm CR, Briginshaw L, Caballero-Perez J, Catarino B, Chen F, Chiyoda S, Chovatia M, Davies KM, Delmans M, Demura T, Dierschke T, Dolan L, Dorantes-Acosta AE, Eklund DM, Florent SN, Flores-Sandoval E, Fujiyama A, Fukuzawa H, Galik B, Grimanelli D, Grimwood J, Grossniklaus U, Hamada T, Haseloff J, Hetherington AJ, Higo A, Hirakawa Y, Hundley HN, Ikeda Y, Inoue K, Inoue SI, Ishida S, Jia Q, Kakita M, Kanazawa T, Kawai Y, Kawashima T, Kennedy M, Kinose K, Kinoshita T, Kohara Y, Koide E, Komatsu K, Kopischke S, Kubo M, Kyozuka J, Lagercrantz U, Lin SS, Lindquist E, Lipzen AM, Lu CW, De Luna E, Martienssen RA, Minamino N, Mizutani M, Mizutani M, Mochizuki N, Monte I, Mosher R, Nagasaki H, Nakagami H, Naramoto S, Nishitani K, Ohtani M, Okamoto T, Okumura M, Phillips J, Pollak B, Reinders A, Rövekamp M, Sano R, Sawa S, Schmid MW, Shirakawa M, Solano R, Spunde A, Suetsugu N, Sugano S, Sugiyama A, Sun R, Suzuki Y, Takenaka M, Takezawa D, Tomogane H, Tsuzuki M, Ueda T, Umeda M, Ward JM, Watanabe Y, Yazaki K, Yokoyama R, Yoshitake Y, Yotsui I, Zachgo S, Schmutz J.

Cell. 2017 Oct 5;171(2):287-304.e15. doi: 10.1016/j.cell.2017.09.030.

33.

Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes.

Pang Z, Kushiyama A, Sun J, Kikuchi T, Yamazaki H, Iwamoto Y, Koriyama H, Yoshida S, Shimamura M, Higuchi M, Kawano T, Takami Y, Rakugi H, Morishita R, Nakagami H.

FASEB J. 2017 Sep;31(9):4053-4063. doi: 10.1096/fj.201700110R. Epub 2017 May 25.

PMID:
28546444
34.

Physician-initiated first-in-human clinical study using a novel angiogenic peptide, AG30/5C, for patients with severe limb ulcers.

Nakagami H, Yamaoka T, Hayashi M, Tanemura A, Takeya Y, Kurinami H, Sugimoto K, Nakamura A, Tomono K, Tamai K, Katayama I, Rakugi H, Kaneda Y.

Geriatr Gerontol Int. 2017 Nov;17(11):2150-2156. doi: 10.1111/ggi.13051. Epub 2017 May 10.

PMID:
28488306
35.

Design of therapeutic vaccines as a novel antibody therapy for cardiovascular diseases.

Nakagami H.

J Cardiol. 2017 Sep;70(3):201-205. doi: 10.1016/j.jjcc.2017.01.010. Epub 2017 Apr 9. Review.

36.

A novel lipoprotein (a) lowering drug, D-47, decreases neointima thickening after vascular injury.

Nakaya Y, Fukuda D, Oyamada T, Ogawa K, Harada N, Nakagami H, Morishita R, Sata M, Sakaue H.

J Med Invest. 2017;64(1.2):64-67. doi: 10.2152/jmi.64.64.

37.

Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress.

Wakayama K, Shimamura M, Suzuki JI, Watanabe R, Koriyama H, Akazawa H, Nakagami H, Mochizuki H, Isobe M, Morishita R.

Stroke. 2017 May;48(5):1362-1368. doi: 10.1161/STROKEAHA.116.016269. Epub 2017 Mar 31.

PMID:
28364024
38.

Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response.

Furlan G, Nakagami H, Eschen-Lippold L, Jiang X, Majovsky P, Kowarschik K, Hoehenwarter W, Lee J, Trujillo M.

Plant Cell. 2017 Apr;29(4):726-745. doi: 10.1105/tpc.16.00654. Epub 2017 Mar 9.

39.

A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction.

Watanabe R, Suzuki JI, Wakayama K, Maejima Y, Shimamura M, Koriyama H, Nakagami H, Kumagai H, Ikeda Y, Akazawa H, Morishita R, Komuro I, Isobe M.

Sci Rep. 2017 Mar 7;7:43920. doi: 10.1038/srep43920.

40.

Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice.

Pang Z, Higuchi M, Koriyama H, Yoshida S, Kurinami H, Shimamura M, Takami Y, Rakugi H, Morishita R, Nakagami H.

FEBS Lett. 2017 Jan;591(1):129-136. doi: 10.1002/1873-3468.12511. Epub 2016 Dec 20.

41.

A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke.

Kurinami H, Shimamura M, Nakagami H, Shimizu H, Koriyama H, Kawano T, Wakayama K, Mochizuki H, Rakugi H, Morishita R.

Sci Rep. 2016 Nov 29;6:38062. doi: 10.1038/srep38062.

42.

Regulation of sugar transporter activity for antibacterial defense in Arabidopsis.

Yamada K, Saijo Y, Nakagami H, Takano Y.

Science. 2016 Dec 16;354(6318):1427-1430. Epub 2016 Nov 24.

PMID:
27884939
43.

The Arabidopsis CERK1-associated kinase PBL27 connects chitin perception to MAPK activation.

Yamada K, Yamaguchi K, Shirakawa T, Nakagami H, Mine A, Ishikawa K, Fujiwara M, Narusaka M, Narusaka Y, Ichimura K, Kobayashi Y, Matsui H, Nomura Y, Nomoto M, Tada Y, Fukao Y, Fukamizo T, Tsuda K, Shirasu K, Shibuya N, Kawasaki T.

EMBO J. 2016 Nov 15;35(22):2468-2483. Epub 2016 Sep 27.

44.

Modulation of plant growth in vivo and identification of kinase substrates using an analog-sensitive variant of CYCLIN-DEPENDENT KINASE A;1.

Harashima H, Dissmeyer N, Hammann P, Nomura Y, Kramer K, Nakagami H, Schnittger A.

BMC Plant Biol. 2016 Sep 26;16(1):209.

45.

RANKL system in vascular and valve calcification with aging.

Kawakami R, Nakagami H, Noma T, Ohmori K, Kohno M, Morishita R.

Inflamm Regen. 2016 Aug 1;36:10. doi: 10.1186/s41232-016-0016-3. eCollection 2016. Review.

46.

Circadian Profiling of the Arabidopsis Proteome Using 2D-DIGE.

Choudhary MK, Nomura Y, Shi H, Nakagami H, Somers DE.

Front Plant Sci. 2016 Jul 12;7:1007. doi: 10.3389/fpls.2016.01007. eCollection 2016.

47.

TDM1 Regulation Determines the Number of Meiotic Divisions.

Cifuentes M, Jolivet S, Cromer L, Harashima H, Bulankova P, Renne C, Crismani W, Nomura Y, Nakagami H, Sugimoto K, Schnittger A, Riha K, Mercier R.

PLoS Genet. 2016 Feb 12;12(2):e1005856. doi: 10.1371/journal.pgen.1005856. eCollection 2016 Feb.

48.

Chitin Nanofiber Elucidates the Elicitor Activity of Polymeric Chitin in Plants.

Egusa M, Matsui H, Urakami T, Okuda S, Ifuku S, Nakagami H, Kaminaka H.

Front Plant Sci. 2015 Dec 9;6:1098. doi: 10.3389/fpls.2015.01098. eCollection 2015.

49.

The Naming of Names: Guidelines for Gene Nomenclature in Marchantia.

Bowman JL, Araki T, Arteaga-Vazquez MA, Berger F, Dolan L, Haseloff J, Ishizaki K, Kyozuka J, Lin SS, Nagasaki H, Nakagami H, Nakajima K, Nakamura Y, Ohashi-Ito K, Sawa S, Shimamura M, Solano R, Tsukaya H, Ueda T, Watanabe Y, Yamato KT, Zachgo S, Kohchi T.

Plant Cell Physiol. 2016 Feb;57(2):257-61. doi: 10.1093/pcp/pcv193. Epub 2015 Dec 7. Review.

50.

Low alpha-synuclein levels in the blood are associated with insulin resistance.

Rodriguez-Araujo G, Nakagami H, Takami Y, Katsuya T, Akasaka H, Saitoh S, Shimamoto K, Morishita R, Rakugi H, Kaneda Y.

Sci Rep. 2015 Jul 10;5:12081. doi: 10.1038/srep12081.

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