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Items: 28

1.

Galactose to tagatose isomerization at moderate temperatures with high conversion and productivity.

Bober JR, Nair NU.

Nat Commun. 2019 Oct 7;10(1):4548. doi: 10.1038/s41467-019-12497-8.

2.

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival.

Nair NU, Das A, Rogkoti VM, Fokkelman M, Marcotte R, de Jong CG, Koedoot E, Lee JS, Meilijson I, Hannenhalli S, Neel BG, de Water BV, Le Dévédec SE, Ruppin E.

Sci Rep. 2019 Jul 29;9(1):10989. doi: 10.1038/s41598-019-47440-w.

3.

Towards creating an extended metabolic model (EMM) for E. coli using enzyme promiscuity prediction and metabolomics data.

Amin SA, Chavez E, Porokhin V, Nair NU, Hassoun S.

Microb Cell Fact. 2019 Jun 13;18(1):109. doi: 10.1186/s12934-019-1156-3.

4.

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy.

Sahu AD, S Lee J, Wang Z, Zhang G, Iglesias-Bartolome R, Tian T, Wei Z, Miao B, Nair NU, Ponomarova O, Friedman AA, Amzallag A, Moll T, Kasumova G, Greninger P, Egan RK, Damon LJ, Frederick DT, Jerby-Arnon L, Wagner A, Cheng K, Park SG, Robinson W, Gardner K, Boland G, Hannenhalli S, Herlyn M, Benes C, Flaherty K, Luo J, Gutkind JS, Ruppin E.

Mol Syst Biol. 2019 Mar 11;15(3):e8323. doi: 10.15252/msb.20188323.

5.

Establishing synthesis pathway-host compatibility via enzyme solubility.

Amin SA, Endalur Gopinarayanan V, Nair NU, Hassoun S.

Biotechnol Bioeng. 2019 Jun;116(6):1405-1416. doi: 10.1002/bit.26959. Epub 2019 Mar 29.

6.

PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein.

Kedan A, Verma N, Saroha A, Shreberk-Shaked M, Müller AK, Nair NU, Lev S.

Cell Death Dis. 2018 Sep 24;9(10):985. doi: 10.1038/s41419-018-1005-z.

7.

Pentose Metabolism in Saccharomyces cerevisiae: The Need to Engineer Global Regulatory Systems.

Endalur Gopinarayanan V, Nair NU.

Biotechnol J. 2019 Jan;14(1):e1800364. doi: 10.1002/biot.201800364. Epub 2018 Sep 19. Review.

8.

A semi-synthetic regulon enables rapid growth of yeast on xylose.

Endalur Gopinarayanan V, Nair NU.

Nat Commun. 2018 Mar 26;9(1):1233. doi: 10.1038/s41467-018-03645-7.

9.

Synthetic biology in probiotic lactic acid bacteria: At the frontier of living therapeutics.

Mays ZJ, Nair NU.

Curr Opin Biotechnol. 2018 Oct;53:224-231. doi: 10.1016/j.copbio.2018.01.028. Epub 2018 Mar 15. Review.

10.

Synthetic Biology Approaches to Engineer Probiotics and Members of the Human Microbiota for Biomedical Applications.

Bober JR, Beisel CL, Nair NU.

Annu Rev Biomed Eng. 2018 Jun 4;20:277-300. doi: 10.1146/annurev-bioeng-062117-121019. Epub 2018 Mar 12. Review.

11.

Selection Finder (SelFi): A computational metabolic engineering tool to enable directed evolution of enzymes.

Hassanpour N, Ullah E, Yousofshahi M, Nair NU, Hassoun S.

Metab Eng Commun. 2017 Mar 1;4:37-47. doi: 10.1016/j.meteno.2017.02.003. eCollection 2017 Jun.

12.

Putative functional genes in idiopathic dilated cardiomyopathy.

Nair NU, Das A, Amit U, Robinson W, Park SG, Basu M, Lugo A, Leor J, Ruppin E, Hannenhalli S.

Sci Rep. 2018 Jan 8;8(1):66. doi: 10.1038/s41598-017-18524-2.

13.

Prediction and Subtyping of Hypertension from Pan-Tissue Transcriptomic and Genetic Analyses.

Basu M, Sharmin M, Das A, Nair NU, Wang K, Lee JS, Chang YC, Ruppin E, Hannenhalli S.

Genetics. 2017 Nov;207(3):1121-1134. doi: 10.1534/genetics.117.300280. Epub 2017 Sep 12.

14.

Toward a genetic tool development pipeline for host-associated bacteria.

Waller MC, Bober JR, Nair NU, Beisel CL.

Curr Opin Microbiol. 2017 Aug;38:156-164. doi: 10.1016/j.mib.2017.05.006. Epub 2017 Jun 15. Review.

15.

Co-utilization of hexoses by a microconsortium of sugar-specific E. coli strains.

Chappell TC, Nair NU.

Biotechnol Bioeng. 2017 Oct;114(10):2309-2318. doi: 10.1002/bit.26351. Epub 2017 Jul 3.

PMID:
28600864
16.

Computational prediction of functional abortive RNA in E. coli.

Marcus JI, Hassoun S, Nair NU.

Genomics. 2017 Jul;109(3-4):196-203. doi: 10.1016/j.ygeno.2017.03.003. Epub 2017 Mar 24.

17.

A maximum-likelihood approach for building cell-type trees by lifting.

Nair NU, Hunter L, Shao M, Grnarova P, Lin Y, Bucher P, E Moret BM.

BMC Genomics. 2016 Jan 11;17 Suppl 1:14. doi: 10.1186/s12864-015-2297-3.

18.

The primary σ factor in Escherichia coli can access the transcription elongation complex from solution in vivo.

Goldman SR, Nair NU, Wells CD, Nickels BE, Hochschild A.

Elife. 2015 Sep 15;4. doi: 10.7554/eLife.10514.

19.

Study of cell differentiation by phylogenetic analysis using histone modification data.

Nair NU, Lin Y, Manasovska A, Antic J, Grnarova P, Sahu AD, Bucher P, Moret BM.

BMC Bioinformatics. 2014 Aug 8;15:269. doi: 10.1186/1471-2105-15-269.

20.

Design and construction of acetyl-CoA overproducing Saccharomyces cerevisiae strains.

Lian J, Si T, Nair NU, Zhao H.

Metab Eng. 2014 Jul;24:139-49. doi: 10.1016/j.ymben.2014.05.010. Epub 2014 May 20.

PMID:
24853351
21.

Probabilistic partitioning methods to find significant patterns in ChIP-Seq data.

Nair NU, Kumar S, Moret BM, Bucher P.

Bioinformatics. 2014 Sep 1;30(17):2406-13. doi: 10.1093/bioinformatics/btu318. Epub 2014 May 7.

PMID:
24812341
22.

ChIPnorm: a statistical method for normalizing and identifying differential regions in histone modification ChIP-seq libraries.

Nair NU, Sahu AD, Bucher P, Moret BM.

PLoS One. 2012;7(8):e39573. doi: 10.1371/journal.pone.0039573. Epub 2012 Aug 3.

23.

Genome-wide evaluation of histone methylation changes associated with leaf senescence in Arabidopsis.

Brusslan JA, Rus Alvarez-Canterbury AM, Nair NU, Rice JC, Hitchler MJ, Pellegrini M.

PLoS One. 2012;7(3):e33151. doi: 10.1371/journal.pone.0033151. Epub 2012 Mar 12.

24.

Mutagenic Inverted Repeats Assisted Genome Engineering (MIRAGE) in Saccharomyces cerevisiae: deletion of gal7.

Nair NU, Zhao H.

Methods Mol Biol. 2012;834:63-73. doi: 10.1007/978-1-61779-483-4_5.

PMID:
22144353
25.

Selective reduction of xylose to xylitol from a mixture of hemicellulosic sugars.

Nair NU, Zhao H.

Metab Eng. 2010 Sep;12(5):462-8. doi: 10.1016/j.ymben.2010.04.005. Epub 2010 May 4.

PMID:
20447465
26.

Protein engineering in designing tailored enzymes and microorganisms for biofuels production.

Wen F, Nair NU, Zhao H.

Curr Opin Biotechnol. 2009 Aug;20(4):412-9. doi: 10.1016/j.copbio.2009.07.001. Epub 2009 Aug 5. Review.

27.

Mutagenic inverted repeat assisted genome engineering (MIRAGE).

Nair NU, Zhao H.

Nucleic Acids Res. 2009 Jan;37(1):e9. doi: 10.1093/nar/gkn943. Epub 2008 Dec 2.

28.

Evolution in reverse: engineering a D-xylose-specific xylose reductase.

Nair NU, Zhao H.

Chembiochem. 2008 May 23;9(8):1213-5. doi: 10.1002/cbic.200700765. No abstract available.

PMID:
18383056

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