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Items: 22


A report of third case of Susac syndrome from India.

Harsha KJ, Nair JS.

Neurol India. 2017 Sep-Oct;65(5):1194-1195. doi: 10.4103/neuroindia.NI_543_16. No abstract available.


Chiari I Malformation Associated with Turner Syndrome.

Harsha KJ, Nair JS.

J Neurosci Rural Pract. 2017 Apr-Jun;8(2):277-280. doi: 10.4103/0976-3147.203840.


Selinexor (KPT-330) Induces Tumor Suppression through Nuclear Sequestration of IκB and Downregulation of Survivin.

Nair JS, Musi E, Schwartz GK.

Clin Cancer Res. 2017 Aug 1;23(15):4301-4311. doi: 10.1158/1078-0432.CCR-16-2632. Epub 2017 Mar 17.


A report on the first case of Tourette syndrome associated with segmental agenesis of corpus callosum.

Harsha KJ, Nair JS.

Neurol India. 2016 Sep-Oct;64(5):1057-8. doi: 10.4103/0028-3886.190302. No abstract available.


Phase II study of MLN8237 (Alisertib) in advanced/metastatic sarcoma.

Dickson MA, Mahoney MR, Tap WD, D'Angelo SP, Keohan ML, Van Tine BA, Agulnik M, Horvath LE, Nair JS, Schwartz GK.

Ann Oncol. 2016 Oct;27(10):1855-60. doi: 10.1093/annonc/mdw281. Epub 2016 Aug 8.


MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas.

Nair JS, Schwartz GK.

Oncotarget. 2016 Mar 15;7(11):12893-903. doi: 10.18632/oncotarget.7335.


Inhibition of polo like kinase 1 in sarcomas induces apoptosis that is dependent on Mcl-1 suppression.

Nair JS, Schwartz GK.

Cell Cycle. 2015;14(19):3101-11. doi: 10.1080/15384101.2015.1078033.


Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.

Miller ML, Molinelli EJ, Nair JS, Sheikh T, Samy R, Jing X, He Q, Korkut A, Crago AM, Singer S, Schwartz GK, Sander C.

Sci Signal. 2013 Sep 24;6(294):ra85. doi: 10.1126/scisignal.2004014.


PTEN regulates sensitivity of melanoma cells to RO4929097, the γ-secretase inhibitor.

Nair JS, Sheikh T, Ho AL, Schwartz GK.

Anticancer Res. 2013 Apr;33(4):1307-16.


Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype.

Ho AL, Musi E, Ambrosini G, Nair JS, Deraje Vasudeva S, de Stanchina E, Schwartz GK.

PLoS One. 2012;7(7):e40439. doi: 10.1371/journal.pone.0040439. Epub 2012 Jul 10.


The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells.

Landau HJ, McNeely SC, Nair JS, Comenzo RL, Asai T, Friedman H, Jhanwar SC, Nimer SD, Schwartz GK.

Mol Cancer Ther. 2012 Aug;11(8):1781-8. doi: 10.1158/1535-7163.MCT-11-0949. Epub 2012 May 31.


An approach for building a personal health information system using conceptual domain knowledge.

Gurupur VP, Suh SC, Selvaggi RR, Karla PR, Nair JS, Ajit S.

J Med Syst. 2012 Dec;36(6):3685-93. doi: 10.1007/s10916-012-9842-2. Epub 2012 Mar 23.


The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent.

Nair JS, Ho AL, Schwartz GK.

Cell Cycle. 2012 Feb 15;11(4):807-17. doi: 10.4161/cc.11.4.19323. Epub 2012 Feb 15.


Validation of the Intensive Care Delirium Screening Checklist in nonintubated intensive care unit patients in a resource-poor medical intensive care setting in South India.

George C, Nair JS, Ebenezer JA, Gangadharan A, Christudas A, Gnanaseelan LK, Jacob KS.

J Crit Care. 2011 Apr;26(2):138-43. doi: 10.1016/j.jcrc.2010.11.002. Epub 2011 Jan 26.


The topoisomerase I poison CPT-11 enhances the effect of the aurora B kinase inhibitor AZD1152 both in vitro and in vivo.

Nair JS, de Stanchina E, Schwartz GK.

Clin Cancer Res. 2009 Mar 15;15(6):2022-30. doi: 10.1158/1078-0432.CCR-08-1826. Epub 2009 Mar 10.


Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780.

Nair JS, Ho AL, Tse AN, Coward J, Cheema H, Ambrosini G, Keen N, Schwartz GK.

Mol Biol Cell. 2009 Apr;20(8):2218-28. doi: 10.1091/mbc.E08-08-0885. Epub 2009 Feb 18.


UV-B exposure enhances senescence of wheat leaves: Modulation by photosynthetically active radiation.

Pradhan MK, Joshi PN, Nair JS, Ramaswamy NK, Iyer RK, Biswal B, Biswal UC.

Radiat Environ Biophys. 2006 Sep;45(3):221-9. Epub 2006 Jul 19.


Ultraviolet-A induced changes in photosystem II of thylakoids: effects of senescence and high growth temperature.

Nayak L, Biswal B, Ramaswamy NK, Iyer RK, Nair JS, Biswal UC.

J Photochem Photobiol B. 2003 May-Jun;70(2):59-65.


Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.

Nair JS, DaFonseca CJ, Tjernberg A, Sun W, Darnell JE Jr, Chait BT, Zhang JJ.

Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5971-6. Epub 2002 Apr 23.


Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.

Nair JS, Kancherla R, Seiter K, Traganos F, Tse-Dinh YC.

Ann N Y Acad Sci. 2000;922:326-9. No abstract available.


Evaluation of topotecan and etoposide for non-Hodgkin lymphoma: correlation of topoisomerase-DNA complex formation with clinical response.

Kancherla RR, Nair JS, Ahmed T, Durrani H, Seiter K, Mannancheril A, Tse-Dinh YC.

Cancer. 2001 Feb 1;91(3):463-71.


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