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Items: 28

1.

Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling.

Singhal H, Greene ME, Zarnke AL, Laine M, Al Abosy R, Chang YF, Dembo AG, Schoenfelt K, Vadhi R, Qiu X, Rao P, Santhamma B, Nair HB, Nickisch KJ, Long HW, Becker L, Brown M, Greene GL.

Oncotarget. 2017 Sep 28;9(4):4282-4300. doi: 10.18632/oncotarget.21378. eCollection 2018 Jan 12.

2.

A prodrug design for improved oral absorption and reduced hepatic interaction.

Ahmed G, Elger W, Meece F, Nair HB, Schneider B, Wyrwa R, Nickisch K.

Bioorg Med Chem. 2017 Oct 15;25(20):5569-5575. doi: 10.1016/j.bmc.2017.08.027. Epub 2017 Aug 24.

PMID:
28886996
3.

Estradiol prodrugs (EP) for efficient oral estrogen treatment and abolished effects on estrogen modulated liver functions.

Elger W, Wyrwa R, Ahmed G, Meece F, Nair HB, Santhamma B, Killeen Z, Schneider B, Meister R, Schubert H, Nickisch K.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):305-311. doi: 10.1016/j.jsbmb.2016.07.008. Epub 2016 Jul 20.

PMID:
27449818
4.

Effects of Combination of Estradiol with Selective Progesterone Receptor Modulators (SPRMs) on Human Breast Cancer Cells In Vitro and In Vivo.

Nair HB, Santhamma B, Krishnegowda NK, Dileep KV, Nickisch KJ.

PLoS One. 2016 Mar 24;11(3):e0151182. doi: 10.1371/journal.pone.0151182. eCollection 2016.

5.

An efficient model of human endometriosis by induced unopposed estrogenicity in baboons.

Nair HB, Baker R, Owston MA, Escalona R, Dick EJ, VandeBerg JL, Nickisch KJ.

Oncotarget. 2016 Mar 8;7(10):10857-69. doi: 10.18632/oncotarget.7516.

6.

Retraction notice to "Thymoquinone poly(lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential" [Biochem. Pharmacol. 79 (2010) 1640-1647].

Ravindran J, Nair HB, Sung B, Prasad S, Tekmal RR, Aggarwal BB.

Biochem Pharmacol. 2016 Feb 15;102:146. doi: 10.1016/j.bcp.2015.11.011. Epub 2016 Feb 20. No abstract available.

PMID:
29065992
7.

Retraction notice to "Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo" [Biochem. Pharmacol. 79 (2010) 330-338].

Anand P, Nair HB, Sung B, Kunnumakkara AB, Yadav VR, Tekmal RR, Aggarwal BB.

Biochem Pharmacol. 2016 Feb 15;102:143. doi: 10.1016/j.bcp.2015.11.008. Epub 2016 Feb 20. No abstract available.

PMID:
29065989
8.

Modeling sunscreen-mediated melanoma prevention in the laboratory opossum (Monodelphis domestica).

Nair HB, Ford A, Dick EJ Jr, Hill RH Jr, VandeBerg JL.

Pigment Cell Melanoma Res. 2014 Sep;27(5):843-5. doi: 10.1111/pcmr.12283. Epub 2014 Jul 10. No abstract available.

PMID:
24931873
9.

Synthesis and antiprogestational properties of novel 17-fluorinated steroids.

Nickisch K, Nair HB, Kesavaram N, Das B, Garfield R, Shi SQ, Bhaskaran SS, Grimm SL, Edwards DP.

Steroids. 2013 Sep;78(9):909-19. doi: 10.1016/j.steroids.2013.04.003. Epub 2013 Apr 20.

PMID:
23607964
10.

Gossypin as a novel selective dual inhibitor of V-RAF murine sarcoma viral oncogene homolog B1 and cyclin-dependent kinase 4 for melanoma.

Bhaskaran S, Dileep KV, Deepa SS, Sadasivan C, Klausner M, Krishnegowda NK, Tekmal RR, VandeBerg JL, Nair HB.

Mol Cancer Ther. 2013 Apr;12(4):361-72. doi: 10.1158/1535-7163.MCT-12-0965. Epub 2013 Mar 29.

11.

Increased expression of macrophage colony-stimulating factor and its receptor in patients with endometriosis.

Budrys NM, Nair HB, Liu YG, Kirma NB, Binkley PA, Kumar S, Schenken RS, Tekmal RR.

Fertil Steril. 2012 May;97(5):1129-35.e1. doi: 10.1016/j.fertnstert.2012.02.007. Epub 2012 Feb 24.

12.

Estrogen receptor-beta mediates the protective effects of aromatase induction in the MMTV-Her-2/neu x aromatase double transgenic mice.

Nair HB, Perla RP, Kirma NB, Krishnegowda NK, Ganapathy M, Rajhans R, Nair SS, Saikumar P, Vadlamudi RK, Tekmal RR.

Horm Cancer. 2012 Apr;3(1-2):26-36. doi: 10.1007/s12672-011-0083-5.

PMID:
22006184
13.

Hyaluronic acid-bound letrozole nanoparticles restore sensitivity to letrozole-resistant xenograft tumors in mice.

Nair HB, Huffman S, Veerapaneni P, Kirma NB, Binkley P, Perla RP, Evans DB, Tekmal RR.

J Nanosci Nanotechnol. 2011 May;11(5):3789-99.

PMID:
21780370
14.

Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling.

Pradeep CR, Köstler WJ, Lauriola M, Granit RZ, Zhang F, Jacob-Hirsch J, Rechavi G, Nair HB, Hennessy BT, Gonzalez-Angulo AM, Tekmal RR, Ben-Porath I, Mills GB, Domany E, Yarden Y.

Oncogene. 2012 Feb 16;31(7):907-17. doi: 10.1038/onc.2011.279. Epub 2011 Jul 11.

15.

Estrogen receptor-β activation in combination with letrozole blocks the growth of breast cancer tumors resistant to letrozole therapy.

Nair HB, Kirma NB, Ganapathy M, Vadlamudi RK, Tekmal RR.

Steroids. 2011 Jul;76(8):792-6. doi: 10.1016/j.steroids.2011.02.038. Epub 2011 Apr 6.

PMID:
21477609
16.

Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer.

Nair HB, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB.

Biochem Pharmacol. 2010 Dec 15;80(12):1833-43. doi: 10.1016/j.bcp.2010.07.021. Epub 2010 Jul 21. Review.

17.

Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential.

Ravindran J, Nair HB, Sung B, Prasad S, Tekmal RR, Aggarwal BB.

Biochem Pharmacol. 2010 Jun 1;79(11):1640-7. doi: 10.1016/j.bcp.2010.01.023. Epub 2010 Jan 25. Retraction in: Biochem Pharmacol. 2016 Feb 15;102:146.

18.

BU-32: a novel proteasome inhibitor for breast cancer.

Agyin JK, Santhamma B, Nair HB, Roy SS, Tekmal RR.

Breast Cancer Res. 2009;11(5):R74. doi: 10.1186/bcr2411.

19.

Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo.

Anand P, Nair HB, Sung B, Kunnumakkara AB, Yadav VR, Tekmal RR, Aggarwal BB.

Biochem Pharmacol. 2010 Feb 1;79(3):330-8. doi: 10.1016/j.bcp.2009.09.003. Epub 2009 Sep 6. Retraction in: Biochem Pharmacol. 2016 Feb 15;102:143.

20.

Elevated aromatase expression correlates with cervical carcinoma progression.

Veerapaneni P, Kirma N, Nair HB, Hammes LS, Hall KL, Tekmal RR.

Gynecol Oncol. 2009 Sep;114(3):496-500. doi: 10.1016/j.ygyno.2009.05.041. Epub 2009 Jun 24.

PMID:
19555998
21.

Induction of endometrial epithelial cell invasion and c-fms expression by transforming growth factor beta.

Liu YG, Tekmal RR, Binkley PA, Nair HB, Schenken RS, Kirma NB.

Mol Hum Reprod. 2009 Oct;15(10):665-73. doi: 10.1093/molehr/gap043. Epub 2009 Jun 8.

22.

Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription.

Nair AS, Nair HB, Lucidi RS, Kirchner AJ, Schenken RS, Tekmal RR, Witz CA.

Fertil Steril. 2008 Oct;90(4 Suppl):1487-95. doi: 10.1016/j.fertnstert.2007.09.047. Epub 2007 Dec 27.

PMID:
18163995
23.

Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells.

Rajhans R, Nair HB, Nair SS, Cortez V, Ikuko K, Kirma NB, Zhou D, Holden AE, Brann DW, Chen S, Tekmal RR, Vadlamudi RK.

Mol Endocrinol. 2008 Mar;22(3):649-64. Epub 2007 Dec 13. Erratum in: Mol Endocrinol. 2013 Jan;27(1):189.

24.

HER-2/neu x aromatase double transgenic mice model: the effects of aromatase overexpression on mammary tumorigenesis.

Tekmal RR, Nair HB, Perla RP, Kirma N.

J Steroid Biochem Mol Biol. 2007 Aug-Sep;106(1-5):111-8. Epub 2007 May 24.

25.
26.

Induction of aromatase expression in cervical carcinomas: effects of endogenous estrogen on cervical cancer cell proliferation.

Nair HB, Luthra R, Kirma N, Liu YG, Flowers L, Evans D, Tekmal RR.

Cancer Res. 2005 Dec 1;65(23):11164-73.

27.

Estrogen receptor alpha is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in the aromatase transgenic mice.

Tekmal RR, Liu YG, Nair HB, Jones J, Perla RP, Lubahn DB, Korach KS, Kirma N.

J Steroid Biochem Mol Biol. 2005 May;95(1-5):9-15.

PMID:
15955696
28.

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