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Cellular and Molecular Adaptation of Arabian Camel to Heat Stress.

Hoter A, Rizk S, Naim HY.

Front Genet. 2019 Jun 19;10:588. doi: 10.3389/fgene.2019.00588. eCollection 2019. Review.


Phylogenetic analysis reveals key residues in substrate hydrolysis in the isomaltase domain of sucrase-isomaltase and its role in starch digestion.

Chaudet MM, Amiri M, Marth N, Naim HY, Rose DR.

Biochim Biophys Acta Gen Subj. 2019 Sep;1863(9):1410-1416. doi: 10.1016/j.bbagen.2019.06.011. Epub 2019 Jun 27.


Recent Trend in Specialty Choices of Medical Students and House Officers from Public Sector Medical Universities, Karachi.

Ali A, Rasheed A, Hussaiin Zaidi SM, Ashraf Jahangeer Alsaani SM, Naim H, Hamid H, Farrukh S.

J Pak Med Assoc. 2019 Apr;69(4):489-494.


Different Niemann-Pick C1 Genotypes Generate Protein Phenotypes that Vary in their Intracellular Processing, Trafficking and Localization.

Shammas H, Kuech EM, Rizk S, Das AM, Naim HY.

Sci Rep. 2019 Mar 28;9(1):5292. doi: 10.1038/s41598-019-41707-y.


Congenital Lactase Deficiency: Mutations, Functional and Biochemical Implications, and Future Perspectives.

Wanes D, Husein DM, Naim HY.

Nutrients. 2019 Feb 22;11(2). pii: E461. doi: 10.3390/nu11020461. Review.


Drug-induced Thrombotic Microangiopathy Caused by Gemcitabine.

Hasan A, Jain AG, Naim H, Munaf A, Everett G.

Cureus. 2018 Aug 2;10(8):e3088. doi: 10.7759/cureus.3088.


Mechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils.

Noack A, Gericke B, von Köckritz-Blickwede M, Menze A, Noack S, Gerhauser I, Osten F, Naim HY, Löscher W.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9590-E9599. doi: 10.1073/pnas.1719642115. Epub 2018 Sep 25.


Vital signs changes during different dental procedures: A prospective longitudinal cross-over clinical trial.

Salma RG, Abu-Naim H, Ahmad O, Akelah D, Salem Y, Midoun E.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jan;127(1):30-39. doi: 10.1016/j.oooo.2018.08.002. Epub 2018 Aug 18.


Drug Resistance and Molecular Epidemiology of Carbapenem Resistant Gram-negative Bacilli Isolates.

Naim H, Rizvi M, Gupta R, Azam M, Taneja N, Shukla I, Khan HM.

J Glob Infect Dis. 2018 Jul-Sep;10(3):133-139. doi: 10.4103/jgid.jgid_74_17.


The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease.

Hoter A, El-Sabban ME, Naim HY.

Int J Mol Sci. 2018 Aug 29;19(9). pii: E2560. doi: 10.3390/ijms19092560. Review.


Molecular cloning, cellular expression and characterization of Arabian camel (Camelus dromedarius) endoplasmin.

Hoter A, Amiri M, Warda M, Naim HY.

Int J Biol Macromol. 2018 Oct 1;117:574-585. doi: 10.1016/j.ijbiomac.2018.05.196. Epub 2018 May 27.


Starch Tolerance and the Short Bowel.

de Laffolie J, Naim HY, Rudloff S, Zimmer KP.

J Pediatr Gastroenterol Nutr. 2018 Jun;66 Suppl 3:S68-S71. doi: 10.1097/MPG.0000000000001962. Review.


Posttranslational Processing and Function of Mucosal Maltases.

Amiri M, Naim HY.

J Pediatr Gastroenterol Nutr. 2018 Jun;66 Suppl 3:S18-S23. doi: 10.1097/MPG.0000000000001826. Review.


Dietary starch breakdown product sensing mobilizes and apically activates α-glucosidases in small intestinal enterocytes.

Chegeni M, Amiri M, Nichols BL, Naim HY, Hamaker BR.

FASEB J. 2018 Jul;32(7):3903-3911. doi: 10.1096/fj.201701029R. Epub 2018 Feb 20.


Differential Glycosylation and Modulation of Camel and Human HSP Isoforms in Response to Thermal and Hypoxic Stresses.

Hoter A, Amiri M, Prince A, Amer H, Warda M, Naim HY.

Int J Mol Sci. 2018 Jan 30;19(2). pii: E402. doi: 10.3390/ijms19020402.


Efficacy of grape seed extract gel in the treatment of chronic periodontitis: A randomized clinical study.

Rayyan M, Terkawi T, Abdo H, Abdel Azim D, Khalaf A, AlKhouli Z, Meziad M, Alshamma'a M, Abu Naim H.

J Investig Clin Dent. 2018 May;9(2):e12318. doi: 10.1111/jicd.12318. Epub 2018 Jan 18.


Clinical Cholecystitis in the Absence of the Gallbladder.

Naim H, Hasan SA, Khalid S, Abbass A, DSouza J.

Cureus. 2017 Nov 10;9(11):e1834. doi: 10.7759/cureus.1834.


Inflammation induced ER stress affects absorptive intestinal epithelial cells function and integrity.

Chotikatum S, Naim HY, El-Najjar N.

Int Immunopharmacol. 2018 Feb;55:336-344. doi: 10.1016/j.intimp.2017.12.016. Epub 2018 Jan 8.


Differentiation and Functionality of Bone Marrow-Derived Mast Cells Depend on Varying Physiologic Oxygen Conditions.

Möllerherm H, Meier K, Schmies K, Fuhrmann H, Naim HY, von Köckritz-Blickwede M, Branitzki-Heinemann K.

Front Immunol. 2017 Nov 30;8:1665. doi: 10.3389/fimmu.2017.01665. eCollection 2017.


Characterization of Mucosal Disaccharidases from Human Intestine.

Amiri M, Naim HY.

Nutrients. 2017 Oct 10;9(10). pii: E1106. doi: 10.3390/nu9101106.


Impact of Virtual Patients as Optional Learning Material in Veterinary Biochemistry Education.

Kleinsorgen C, von Köckritz-Blickwede M, Naim HY, Branitzki-Heinemann K, Kankofer M, Mándoki M, Adler M, Tipold A, Ehlers JP.

J Vet Med Educ. Summer 2018;45(2):177-187. doi: 10.3138/jvme.1016-155r1. Epub 2017 Sep 8.


Total knee Arthroplasty: risk factors for allogeneic blood transfusions in the South Asian population.

Mufarrih SH, Qureshi NQ, Ali A, Malik AT, Naim H, Noordin S.

BMC Musculoskelet Disord. 2017 Aug 23;18(1):359. doi: 10.1186/s12891-017-1728-5.


Alarming emergence, molecular characterization, and outcome of blaNDM-1 in patients infected with multidrug-resistant Gram-negative bacilli in a tertiary care hospital.

Naim H, Rizvi M, Azam M, Gupta R, Taneja N, Shukla I, Khan HM.

J Lab Physicians. 2017 Jul-Sep;9(3):170-176. doi: 10.4103/0974-2727.208264.


In Vitro Testing of Crude Natural Plant Extracts from Costa Rica for Their Ability to Boost Innate Immune Cells against Staphylococcus aureus.

Yaseen R, Branitzki-Heinemann K, Moubasher H, Setzer WN, Naim HY, von Köckritz-Blickwede M.

Biomedicines. 2017 Jul 5;5(3). pii: E40. doi: 10.3390/biomedicines5030040.


Utilization and acceptance of virtual patients in veterinary basic sciences - the vetVIP-project.

Kleinsorgen C, Kankofer M, Gradzki Z, Mandoki M, Bartha T, von Köckritz-Blickwede M, Naim HY, Beyerbach M, Tipold A, Ehlers JP.

GMS J Med Educ. 2017 May 15;34(2):Doc19. doi: 10.3205/zma001096. eCollection 2017.


Hypoxia Modulates the Response of Mast Cells to Staphylococcus aureus Infection.

Möllerherm H, Branitzki-Heinemann K, Brogden G, Elamin AA, Oehlmann W, Fuhrmann H, Singh M, Naim HY, von Köckritz-Blickwede M.

Front Immunol. 2017 May 11;8:541. doi: 10.3389/fimmu.2017.00541. eCollection 2017.


Structure-function analysis of human sucrase-isomaltase identifies key residues required for catalytic activity.

Gericke B, Schecker N, Amiri M, Naim HY.

J Biol Chem. 2017 Jun 30;292(26):11070-11078. doi: 10.1074/jbc.M117.791939. Epub 2017 May 18.


Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps.

Brogden G, Neumann A, Husein DM, Reuner F, Naim HY, von Köckritz-Blickwede M.

J Vis Exp. 2017 Mar 29;(121). doi: 10.3791/54667.


Case study on the pathophysiology of Fabry disease: abnormalities of cellular membranes can be reversed by substrate reduction in vitro.

Brogden G, Shammas H, Maalouf K, Naim SL, Wetzel G, Amiri M, von Köckritz-Blickwede M, Das AM, Naim HY.

Biosci Rep. 2017 Apr 28;37(2). pii: BSR20160402. doi: 10.1042/BSR20160402. Print 2017 Apr 30.


Antimicrobial activity of HL-60 cells compared to primary blood-derived neutrophils against Staphylococcus aureus.

Yaseen R, Blodkamp S, Lüthje P, Reuner F, Völlger L, Naim HY, von Köckritz-Blickwede M.

J Negat Results Biomed. 2017 Feb 19;16(1):2. doi: 10.1186/s12952-017-0067-2.


Molecular pathogenicity of novel sucrase-isomaltase mutations found in congenital sucrase-isomaltase deficiency patients.

Gericke B, Amiri M, Scott CR, Naim HY.

Biochim Biophys Acta Mol Basis Dis. 2017 Mar;1863(3):817-826. doi: 10.1016/j.bbadis.2016.12.017. Epub 2017 Jan 3.


Formation of Neutrophil Extracellular Traps under Low Oxygen Level.

Branitzki-Heinemann K, Möllerherm H, Völlger L, Husein DM, de Buhr N, Blodkamp S, Reuner F, Brogden G, Naim HY, von Köckritz-Blickwede M.

Front Immunol. 2016 Nov 25;7:518. eCollection 2016.


Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome.

Henström M, Diekmann L, Bonfiglio F, Hadizadeh F, Kuech EM, von Köckritz-Blickwede M, Thingholm LB, Zheng T, Assadi G, Dierks C, Heine M, Philipp U, Distl O, Money ME, Belheouane M, Heinsen FA, Rafter J, Nardone G, Cuomo R, Usai-Satta P, Galeazzi F, Neri M, Walter S, Simrén M, Karling P, Ohlsson B, Schmidt PT, Lindberg G, Dlugosz A, Agreus L, Andreasson A, Mayer E, Baines JF, Engstrand L, Portincasa P, Bellini M, Stanghellini V, Barbara G, Chang L, Camilleri M, Franke A, Naim HY, D'Amato M.

Gut. 2018 Feb;67(2):263-270. doi: 10.1136/gutjnl-2016-312456. Epub 2016 Nov 21.


Alterations in membrane trafficking and pathophysiological implications in lysosomal storage disorders.

Kuech EM, Brogden G, Naim HY.

Biochimie. 2016 Nov;130:152-162. doi: 10.1016/j.biochi.2016.09.011. Epub 2016 Sep 21. Review.


Measuring oxygen levels in Caco-2 cultures.

Zeitouni NE, Fandrey J, Naim HY, von Köckritz-Blickwede M.

Hypoxia (Auckl). 2015 Oct 9;3:53-66. eCollection 2015.


Structural determinants for transport of lactase phlorizin-hydrolase in the early secretory pathway as a multi-domain membrane glycoprotein.

Diekmann L, Behrendt M, Amiri M, Naim HY.

Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3119-3128. doi: 10.1016/j.bbagen.2016.10.016. Epub 2016 Oct 21.


Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells "in vitro" and correlating with progression "in vivo".

Perico ME, Grasso S, Brunelli M, Martignoni G, Munari E, Moiso E, Fracasso G, Cestari T, Naim HY, Bronte V, Colombatti M, Ramarli D.

Oncotarget. 2016 Nov 8;7(45):74189-74202. doi: 10.18632/oncotarget.12404.


Guarea kunthiana Bark Extract Enhances the Antimicrobial Activities of Human and Bovine Neutrophils.

Jerjomiceva N, Seri H, Yaseen R, de Buhr N, Setzer WN, Naim HY, von Köckritz-Blickwede M.

Nat Prod Commun. 2016 Jun;11(6):767-70.


Molecular biology of the gut.

Naim HY, Zimmer KP, Nichols B.

Mol Cell Pediatr. 2016 Dec;3(1):32. doi: 10.1186/s40348-016-0059-1. Epub 2016 Aug 12. No abstract available.


Cross-talk between intestinal epithelial cells and immune cells in inflammatory bowel disease.

Al-Ghadban S, Kaissi S, Homaidan FR, Naim HY, El-Sabban ME.

Sci Rep. 2016 Jul 15;6:29783. doi: 10.1038/srep29783.


Intercellular transfer of P-glycoprotein in human blood-brain barrier endothelial cells is increased by histone deacetylase inhibitors.

Noack A, Noack S, Buettner M, Naim HY, Löscher W.

Sci Rep. 2016 Jul 4;6:29253. doi: 10.1038/srep29253.


Iron-chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils.

Völlger L, Akong-Moore K, Cox L, Goldmann O, Wang Y, Schäfer ST, Naim HY, Nizet V, von Köckritz-Blickwede M.

Biosci Rep. 2016 May 20;36(3). pii: e00333. doi: 10.1042/BSR20160031. Print 2016 Jul.


Propensity scoring - A novel research methodology.

Naim H, Zaidi AA, Hasan SA.

J Pak Med Assoc. 2016 Apr;66(4):495. No abstract available.


Effects of SecDF on the antimicrobial functions of cathelicidins against Staphylococcus aureus.

Blodkamp S, Kadlec K, Gutsmann T, Quiblier C, Naim HY, Schwarz S, von Köckritz-Blickwede M.

Vet Microbiol. 2017 Feb;200:52-58. doi: 10.1016/j.vetmic.2016.03.021. Epub 2016 Mar 31.


The impact of hypoxia on intestinal epithelial cell functions: consequences for invasion by bacterial pathogens.

Zeitouni NE, Chotikatum S, von Köckritz-Blickwede M, Naim HY.

Mol Cell Pediatr. 2016 Dec;3(1):14. doi: 10.1186/s40348-016-0041-y. Epub 2016 Mar 22. Review.


Endocytosis in enterocytes.

Zimmer KP, de Laffolie J, Barone MV, Naim HY.

Wien Med Wochenschr. 2016 May;166(7-8):205-10. doi: 10.1007/s10354-016-0448-z. Epub 2016 Mar 18. Review.


The multiple roles of sucrase-isomaltase in the intestinal physiology.

Gericke B, Amiri M, Naim HY.

Mol Cell Pediatr. 2016 Dec;3(1):2. doi: 10.1186/s40348-016-0033-y. Epub 2016 Jan 26.


What to do with high autofluorescence background in pancreatic tissues - an efficient Sudan black B quenching method for specific immunofluorescence labelling.

Erben T, Ossig R, Naim HY, Schnekenburger J.

Histopathology. 2016 Sep;69(3):406-22. doi: 10.1111/his.12935. Epub 2016 May 5.


Hypoxia Decreases Invasin-Mediated Yersinia enterocolitica Internalization into Caco-2 Cells.

Zeitouni NE, Dersch P, Naim HY, von Köckritz-Blickwede M.

PLoS One. 2016 Jan 5;11(1):e0146103. doi: 10.1371/journal.pone.0146103. eCollection 2016.


A Novel SLC27A4 Splice Acceptor Site Mutation in Great Danes with Ichthyosis.

Metzger J, Wöhlke A, Mischke R, Hoffmann A, Hewicker-Trautwein M, Küch EM, Naim HY, Distl O.

PLoS One. 2015 Oct 27;10(10):e0141514. doi: 10.1371/journal.pone.0141514. eCollection 2015.

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