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Items: 1 to 50 of 71

1.

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

Sohal SS, Eapen MS, Naidu VGM, Sharma P.

ERJ Open Res. 2019 Feb 11;5(1). pii: 00159-2018. doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

PMID:
30775377
2.

Corrigendum to "Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice." [Behav. Brain Res. 344 (2018) 73-84].

Kv A, Madhana RM, Js IC, Lahkar M, Sinha S, Naidu VGM.

Behav Brain Res. 2019 Feb 1;359:973-974. doi: 10.1016/j.bbr.2018.06.018. Epub 2018 Oct 6. No abstract available.

PMID:
30297317
3.

Identification and characterization of stress degradation products of sumatriptan succinate by using LC/Q-TOF-ESI-MS/MS and NMR: Toxicity evaluation of degradation products.

Udutha S, Shankar G, Borkar RM, Kumar K, Srinivasulu G, Guntuku L, Naidu VGM, Srinivas R.

J Mass Spectrom. 2018 Oct;53(10):963-975. doi: 10.1002/jms.4266. Epub 2018 Aug 15.

PMID:
29987857
4.

Abietic acid attenuates RANKL induced osteoclastogenesis and inflammation associated osteolysis by inhibiting the NF-KB and MAPK signaling.

Thummuri D, Guntuku L, Challa VS, Ramavat RN, Naidu VGM.

J Cell Physiol. 2018 Jan;234(1):443-453. doi: 10.1002/jcp.26575. Epub 2018 Jun 22.

PMID:
29932225
5.

Corrigendum to "Preparation, characterization, and cytotoxicity studies of niclosamide loaded mesoporous drug delivery systems" [Int. J. Pharm. 528 (2017) 202-214].

Pardhi V, Chavan RB, Thipparaboina R, Thatikonda S, Naidu VGM, Shastri NR.

Int J Pharm. 2018 Jun 10;544(1):304-306. doi: 10.1016/j.ijpharm.2018.04.041. Epub 2018 May 1. No abstract available.

PMID:
29728271
6.

Synthesis of some novel orcinol based coumarin triazole hybrids with capabilities to inhibit RANKL-induced osteoclastogenesis through NF-κB signaling pathway.

Rama Krishna B, Thummuri D, Naidu VGM, Ramakrishna S, Venkata Mallavadhani U.

Bioorg Chem. 2018 Aug;78:94-102. doi: 10.1016/j.bioorg.2018.03.005. Epub 2018 Mar 7.

PMID:
29550534
7.

Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.

Kv A, Madhana RM, Js IC, Lahkar M, Sinha S, Naidu VGM.

Behav Brain Res. 2018 May 15;344:73-84. doi: 10.1016/j.bbr.2018.02.009. Epub 2018 Feb 13. Erratum in: Behav Brain Res. 2019 Feb 1;359:973-974.

PMID:
29452193
8.

Curcumin inspired 2-chloro/phenoxy quinoline analogues: Synthesis and biological evaluation as potential anticancer agents.

Sri Ramya PV, Guntuku L, Angapelly S, Karri S, Digwal CS, Babu BN, Naidu VGM, Kamal A.

Bioorg Med Chem Lett. 2018 Mar 1;28(5):892-898. doi: 10.1016/j.bmcl.2018.01.070. Epub 2018 Feb 2.

PMID:
29429834
9.

Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 2,4-thiazolidinedione derivatives as PPAR-γ modulators.

Naim MJ, Alam O, Alam MJ, Shaquiquzzaman M, Alam MM, Naidu VGM.

Arch Pharm (Weinheim). 2018 Apr;351(3-4):e1700223. doi: 10.1002/ardp.201700223. Epub 2018 Feb 5.

PMID:
29400412
10.

Amelioration of streptozotocin-induced type 2 diabetes mellitus in Wistar rats by arachidonic acid.

Gundala NKV, Naidu VGM, Das UN.

Biochem Biophys Res Commun. 2018 Jan 29;496(1):105-113. doi: 10.1016/j.bbrc.2018.01.007. Epub 2018 Jan 6.

PMID:
29309791
11.

4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.

Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.

Eur J Med Chem. 2018 Jan 20;144:595-611. doi: 10.1016/j.ejmech.2017.12.050. Epub 2017 Dec 14.

PMID:
29289884
12.

Synthesis and biological evaluation of curcumin inspired imidazo[1,2-a]pyridine analogues as tubulin polymerization inhibitors.

Ramya PVS, Guntuku L, Angapelly S, Digwal CS, Lakshmi UJ, Sigalapalli DK, Babu BN, Naidu VGM, Kamal A.

Eur J Med Chem. 2018 Jan 1;143:216-231. doi: 10.1016/j.ejmech.2017.11.010. Epub 2017 Nov 5.

PMID:
29174816
13.

Design, synthesis and molecular docking of thiazolidinedione based benzene sulphonamide derivatives containing pyrazole core as potential anti-diabetic agents.

Naim MJ, Alam O, Alam MJ, Hassan MQ, Siddiqui N, Naidu VGM, Alam MI.

Bioorg Chem. 2018 Feb;76:98-112. doi: 10.1016/j.bioorg.2017.11.010. Epub 2017 Nov 16.

PMID:
29169079
14.

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-κB and MAPK signalling.

Thummuri D, Naidu VGM, Chaudhari P.

J Mol Med (Berl). 2017 Oct;95(10):1065-1076. doi: 10.1007/s00109-017-1553-1. Epub 2017 Jul 4.

PMID:
28674855
15.

Synthesis of thiazole linked indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors.

Guggilapu SD, Guntuku L, Reddy TS, Nagarsenkar A, Sigalapalli DK, Naidu VGM, Bhargava SK, Bathini NB.

Eur J Med Chem. 2017 Sep 29;138:83-95. doi: 10.1016/j.ejmech.2017.06.025. Epub 2017 Jun 15.

PMID:
28648953
16.

Uridine Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice.

Jeengar MK, Thummuri D, Magnusson M, Naidu VGM, Uppugunduri S.

Sci Rep. 2017 Jun 20;7(1):3924. doi: 10.1038/s41598-017-04041-9.

17.

Synthesis, molecular docking and anti-diabetic evaluation of 2,4-thiazolidinedione based amide derivatives.

Naim MJ, Alam MJ, Nawaz F, Naidu VGM, Aaghaz S, Sahu M, Siddiqui N, Alam O.

Bioorg Chem. 2017 Aug;73:24-36. doi: 10.1016/j.bioorg.2017.05.007. Epub 2017 May 6.

PMID:
28582649
18.

Forced degradation studies of lansoprazole using LC-ESI HRMS and 1 H-NMR experiments: in vitro toxicity evaluation of major degradation products.

Shankar G, Borkar RM, Suresh U, Guntuku L, Naidu VGM, Nagesh N, Srinivas R.

J Mass Spectrom. 2017 Jul;52(7):459-471. doi: 10.1002/jms.3949.

PMID:
28544042
19.

Fast dissolving drug-drug eutectics with improved compressibility and synergistic effects.

Thipparaboina R, Thumuri D, Chavan R, Naidu VGM, Shastri NR.

Eur J Pharm Sci. 2017 Jun 15;104:82-89. doi: 10.1016/j.ejps.2017.03.042. Epub 2017 Mar 31.

PMID:
28366649
20.

Arachidonic acid and lipoxinA4 attenuate streptozotocin-induced cytotoxicity to RIN5 F cells in vitro and type 1 and type 2 diabetes mellitus in vivo.

Gundala NKV, Naidu VGM, Das UN.

Nutrition. 2017 Mar;35:61-80. doi: 10.1016/j.nut.2016.10.004. Epub 2016 Oct 15.

PMID:
28241993
21.

Synthesis of 2,3,6,7-tetramethoxyphenanthren-9-amine: An efficient precursor to access new 4-aza-2,3-dihydropyridophenanthrenes as apoptosis inducing agents.

Kumar NP, Sharma P, Reddy TS, Nekkanti S, Shankaraiah N, Lalita G, Sujanakumari S, Bhargava SK, Naidu VGM, Kamal A.

Eur J Med Chem. 2017 Feb 15;127:305-317. doi: 10.1016/j.ejmech.2017.01.001. Epub 2017 Jan 3.

PMID:
28068602
22.

Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors.

Sri Ramya PV, Angapelly S, Guntuku L, Singh Digwal C, Nagendra Babu B, Naidu VGM, Kamal A.

Eur J Med Chem. 2017 Feb 15;127:100-114. doi: 10.1016/j.ejmech.2016.12.043. Epub 2016 Dec 23.

PMID:
28038323
23.

Arachidonic acid and lipoxin A4 attenuate alloxan-induced cytotoxicity to RIN5F cells in vitro and type 1 diabetes mellitus in vivo.

Gundala NKV, Naidu VGM, Das UN.

Biofactors. 2017 Mar;43(2):251-271. doi: 10.1002/biof.1336. Epub 2016 Nov 15.

PMID:
27862450
24.

Synthesis and apoptosis inducing studies of triazole linked 3-benzylidene isatin derivatives.

Nagarsenkar A, Guntuku L, Guggilapu SD, K DB, Gannoju S, Naidu VGM, Bathini NB.

Eur J Med Chem. 2016 Nov 29;124:782-793. doi: 10.1016/j.ejmech.2016.09.009. Epub 2016 Sep 4.

PMID:
27639369
25.

Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents.

Sharma P, Srinivasa Reddy T, Thummuri D, Senwar KR, Praveen Kumar N, Naidu VGM, Bhargava SK, Shankaraiah N.

Eur J Med Chem. 2016 Nov 29;124:608-621. doi: 10.1016/j.ejmech.2016.08.029. Epub 2016 Aug 18.

PMID:
27614408
26.

Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.

Shrivastava S, Jeengar MK, Thummuri D, Koval A, Katanaev VL, Marepally S, Naidu VGM.

Biofactors. 2017 Mar;43(2):152-169. doi: 10.1002/biof.1315. Epub 2016 Sep 1.

PMID:
27580587
27.

New (E)-1-alkyl-1H-benzo[d]imidazol-2-yl)methylene)indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies.

Sharma P, Thummuri D, Reddy TS, Senwar KR, Naidu VGM, Srinivasulu G, Bharghava SK, Shankaraiah N.

Eur J Med Chem. 2016 Oct 21;122:584-600. doi: 10.1016/j.ejmech.2016.07.019. Epub 2016 Jul 11.

PMID:
27448916
28.

DABCO-catalyzed one-pot three component synthesis of dihydropyrano[3,2-c]chromene substituted quinazolines and their evaluation towards anticancer activity.

Vodnala S, Bhavani AK, Kamutam R, Naidu VG, Promila, Prabhakar Ch.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):3973-7. doi: 10.1016/j.bmcl.2016.07.003. Epub 2016 Jul 7.

PMID:
27432765
29.

Design and synthesis of 4'-O-alkylamino-tethered-benzylideneindolin-2-ones as potent cytotoxic and apoptosis inducing agents.

Senwar KR, Reddy TS, Thummuri D, Sharma P, Bharghava SK, Naidu VG, Shankaraiah N.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):4061-9. doi: 10.1016/j.bmcl.2016.06.077. Epub 2016 Jun 28.

PMID:
27397498
30.

Synthesis and biological evaluation of oxindole linked indolyl-pyrimidine derivatives as potential cytotoxic agents.

Prajapti SK, Nagarsenkar A, Guggilapu SD, Gupta KK, Allakonda L, Jeengar MK, Naidu VGM, Babu BN.

Bioorg Med Chem Lett. 2016 Jul 1;26(13):3024-3028. doi: 10.1016/j.bmcl.2016.05.019. Epub 2016 May 7.

PMID:
27210438
31.

Amelioration of FCA induced arthritis on topical application of curcumin in combination with emu oil.

Jeengar MK, Shrivastava S, Mouli Veeravalli SC, Naidu VG, Sistla R.

Nutrition. 2016 Sep;32(9):955-64. doi: 10.1016/j.nut.2016.02.009. Epub 2016 Mar 8.

PMID:
27178879
32.

Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents.

Senwar KR, Reddy TS, Thummuri D, Sharma P, Naidu VG, Srinivasulu G, Shankaraiah N.

Eur J Med Chem. 2016 Aug 8;118:34-46. doi: 10.1016/j.ejmech.2016.04.025. Epub 2016 Apr 11.

PMID:
27128173
33.

Emu oil based nano-emulgel for topical delivery of curcumin.

Jeengar MK, Rompicharla SV, Shrivastava S, Chella N, Shastri NR, Naidu VG, Sistla R.

Int J Pharm. 2016 Jun 15;506(1-2):222-36. doi: 10.1016/j.ijpharm.2016.04.052. Epub 2016 Apr 22.

PMID:
27109049
34.

Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer.

Kulhari H, Pooja D, Shrivastava S, Kuncha M, Naidu VG, Bansal V, Sistla R, Adams DJ.

Sci Rep. 2016 Apr 7;6:23179. doi: 10.1038/srep23179.

35.

Mitochondrial Dysfunction in Gliomas: Pharmacotherapeutic Potential of Natural Compounds.

Guntuku L, Naidu VG, Yerra VG.

Curr Neuropharmacol. 2016;14(6):567-83. Review.

36.

Design and synthesis of C3-tethered 1,2,3-triazolo-β-carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies.

Shankaraiah N, Jadala C, Nekkanti S, Senwar KR, Nagesh N, Shrivastava S, Naidu VG, Sathish M, Kamal A.

Bioorg Chem. 2016 Feb;64:42-50. doi: 10.1016/j.bioorg.2015.11.005. Epub 2015 Nov 23.

PMID:
26657602
37.

H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation.

Sharma P, Senwar KR, Jeengar MK, Reddy TS, Naidu VG, Kamal A, Shankaraiah N.

Eur J Med Chem. 2015 Nov 2;104:11-24. doi: 10.1016/j.ejmech.2015.09.025. Epub 2015 Sep 16.

PMID:
26413726
38.

Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies.

Senwar KR, Sharma P, Reddy TS, Jeengar MK, Nayak VL, Naidu VG, Kamal A, Shankaraiah N.

Eur J Med Chem. 2015 Sep 18;102:413-24. doi: 10.1016/j.ejmech.2015.08.017. Epub 2015 Aug 12.

PMID:
26301558
39.

One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.

Shankaraiah N, Kumar NP, Amula SB, Nekkanti S, Jeengar MK, Naidu VG, Reddy TS, Kamal A.

Bioorg Med Chem Lett. 2015 Oct 1;25(19):4239-44. doi: 10.1016/j.bmcl.2015.07.100. Epub 2015 Aug 6.

PMID:
26292628
40.

Preclinical drug metabolism and pharmacokinetics of salinomycin, a potential candidate for targeting human cancer stem cells.

Resham K, Patel PN, Thummuri D, Guntuku L, Shah V, Bambal RB, Naidu VG.

Chem Biol Interact. 2015 Oct 5;240:146-52. doi: 10.1016/j.cbi.2015.08.007. Epub 2015 Aug 14.

PMID:
26282489
41.

Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK Signalling.

Thummuri D, Jeengar MK, Shrivastava S, Nemani H, Ramavat RN, Chaudhari P, Naidu VG.

Pharmacol Res. 2015 Sep;99:63-73. doi: 10.1016/j.phrs.2015.05.006. Epub 2015 May 28.

PMID:
26022736
42.

Albumin anchored docetaxel lipid nanoemulsion for improved targeting efficiency - preparation, characterization, cytotoxic, antitumor and in vivo imaging studies.

Muzammil Afzal S, Naidu VG, Harishankar N, Kishan V.

Drug Deliv. 2016 May;23(4):1355-63. doi: 10.3109/10717544.2015.1030715. Epub 2015 May 19.

PMID:
25987186
43.

Adenosine conjugated lipidic nanoparticles for enhanced tumor targeting.

Swami R, Singh I, Jeengar MK, Naidu VG, Khan W, Sistla R.

Int J Pharm. 2015;486(1-2):287-96. doi: 10.1016/j.ijpharm.2015.03.065. Epub 2015 Mar 31.

PMID:
25839415
44.

Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways.

Shrivastava S, Jeengar MK, Reddy VS, Reddy GB, Naidu VG.

Exp Mol Pathol. 2015 Jun;98(3):313-27. doi: 10.1016/j.yexmp.2015.03.031. Epub 2015 Mar 26.

PMID:
25818165
45.

Author's response re. "Review on emu products for use as complementary and alternative medicine".

Jeengar MK, Shrivastava S, Naidu VG.

Nutrition. 2015 Feb;31(2):415-6. doi: 10.1016/j.nut.2014.10.003. Epub 2014 Oct 31. No abstract available.

46.

Re. "Sucrose, fructose, glucose and their link to metabolic syndrome and cancer".

Kumar A, Jeengar MK, Naidu VG.

Nutrition. 2015 Jan;31(1):258-9. doi: 10.1016/j.nut.2014.09.001. Epub 2014 Oct 8. No abstract available.

PMID:
25466674
47.

Design, synthesis and anticancer evaluation of tetrahydro-β-carboline-hydantoin hybrids.

Shankaraiah N, Nekkanti S, Chudasama KJ, Senwar KR, Sharma P, Jeengar MK, Naidu VG, Srinivasulu V, Srinivasulu G, Kamal A.

Bioorg Med Chem Lett. 2014 Dec 1;24(23):5413-7.

PMID:
25453799
48.

Review on emu products for use as complementary and alternative medicine.

Jeengar MK, Kumar PS, Thummuri D, Shrivastava S, Guntuku L, Sistla R, Naidu VG.

Nutrition. 2015 Jan;31(1):21-7. doi: 10.1016/j.nut.2014.04.004. Epub 2014 Apr 19. Review.

PMID:
25441585
49.

Curcumin: a pleiotropic phytonutrient in diabetic complications.

Jeenger MK, Shrivastava S, Yerra VG, Naidu VG, Ramakrishna S, Kumar A.

Nutrition. 2015 Feb;31(2):276-82. doi: 10.1016/j.nut.2014.06.015. Epub 2014 Jul 19. Review.

PMID:
25441584
50.

Antioxidant and hepatoprotective effects of Boswellia ovalifoliolata bark extracts.

Mahesh BU, Shrivastava S, Pragada RR, Naidu VG, Sistla R.

Chin J Nat Med. 2014 Sep;12(9):663-71. doi: 10.1016/S1875-5364(14)60101-1.

PMID:
25263977

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