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Items: 1 to 50 of 137

1.

Short-chain diamines are the physiological substrates of PACE family efflux pumps.

Hassan KA, Naidu V, Edgerton JR, Mettrick KA, Liu Q, Fahmy L, Li L, Jackson SM, Ahmad I, Sharples D, Henderson PJF, Paulsen IT.

Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):18015-18020. doi: 10.1073/pnas.1901591116. Epub 2019 Aug 15.

2.

Formulation and evaluation of cyclodextrin complexes for improved anticancer activity of repurposed drug: Niclosamide.

Lodagekar A, Borkar RM, Thatikonda S, Chavan RB, Naidu VGM, Shastri NR, Srinivas R, Chella N.

Carbohydr Polym. 2019 May 15;212:252-259. doi: 10.1016/j.carbpol.2019.02.041. Epub 2019 Feb 13.

PMID:
30832855
3.

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

Sohal SS, Eapen MS, Naidu VGM, Sharma P.

ERJ Open Res. 2019 Feb 11;5(1). pii: 00159-2018. doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

4.

Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies.

Jiang JH, Hassan KA, Begg SL, Rupasinghe TWT, Naidu V, Pederick VG, Khorvash M, Whittall JJ, Paton JC, Paulsen IT, McDevitt CA, Peleg AY, Eijkelkamp BA.

MBio. 2019 Feb 5;10(1). pii: e02056-18. doi: 10.1128/mBio.02056-18.

5.

AMPK activating and anti adipogenic potential of Hibiscus rosa sinensis flower in 3T3-L1 cells.

Lingesh A, Paul D, Naidu V, Satheeshkumar N.

J Ethnopharmacol. 2019 Apr 6;233:123-130. doi: 10.1016/j.jep.2018.12.039. Epub 2018 Dec 26.

PMID:
30593890
6.

Impact of Maternal Air Pollution Exposure on Children's Lung Health: An Indian Perspective.

Saha P, Johny E, Dangi A, Shinde S, Brake S, Eapen MS, Sohal SS, Naidu V, Sharma P.

Toxics. 2018 Nov 16;6(4). pii: E68. doi: 10.3390/toxics6040068. Review.

7.

Corrigendum to "Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice." [Behav. Brain Res. 344 (2018) 73-84].

Kv A, Madhana RM, Js IC, Lahkar M, Sinha S, Naidu VGM.

Behav Brain Res. 2019 Feb 1;359:973-974. doi: 10.1016/j.bbr.2018.06.018. Epub 2018 Oct 6. No abstract available.

PMID:
30297317
8.

Non-referral of potential organ donors in South Africa: insights, challenges and ethical dilemmas.

Naidoo P, Etheredge HR, Rambiritch V, Singh A, Mahoney S, Naidu V.

Pan Afr Med J. 2018 Apr 24;29:223. doi: 10.11604/pamj.2018.29.223.14756. eCollection 2018.

9.

Identification and characterization of stress degradation products of sumatriptan succinate by using LC/Q-TOF-ESI-MS/MS and NMR: Toxicity evaluation of degradation products.

Udutha S, Shankar G, Borkar RM, Kumar K, Srinivasulu G, Guntuku L, Naidu VGM, Srinivas R.

J Mass Spectrom. 2018 Oct;53(10):963-975. doi: 10.1002/jms.4266. Epub 2018 Aug 15.

PMID:
29987857
10.

Abietic acid attenuates RANKL induced osteoclastogenesis and inflammation associated osteolysis by inhibiting the NF-KB and MAPK signaling.

Thummuri D, Guntuku L, Challa VS, Ramavat RN, Naidu VGM.

J Cell Physiol. 2018 Jan;234(1):443-453. doi: 10.1002/jcp.26575. Epub 2018 Jun 22.

PMID:
29932225
11.

Corrigendum to "Preparation, characterization, and cytotoxicity studies of niclosamide loaded mesoporous drug delivery systems" [Int. J. Pharm. 528 (2017) 202-214].

Pardhi V, Chavan RB, Thipparaboina R, Thatikonda S, Naidu VGM, Shastri NR.

Int J Pharm. 2018 Jun 10;544(1):304-306. doi: 10.1016/j.ijpharm.2018.04.041. Epub 2018 May 1. No abstract available.

PMID:
29728271
12.

Synthesis of some novel orcinol based coumarin triazole hybrids with capabilities to inhibit RANKL-induced osteoclastogenesis through NF-κB signaling pathway.

Rama Krishna B, Thummuri D, Naidu VGM, Ramakrishna S, Venkata Mallavadhani U.

Bioorg Chem. 2018 Aug;78:94-102. doi: 10.1016/j.bioorg.2018.03.005. Epub 2018 Mar 7.

PMID:
29550534
13.

Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.

Kv A, Madhana RM, Js IC, Lahkar M, Sinha S, Naidu VGM.

Behav Brain Res. 2018 May 15;344:73-84. doi: 10.1016/j.bbr.2018.02.009. Epub 2018 Feb 13. Erratum in: Behav Brain Res. 2019 Feb 1;359:973-974.

PMID:
29452193
14.

Curcumin inspired 2-chloro/phenoxy quinoline analogues: Synthesis and biological evaluation as potential anticancer agents.

Sri Ramya PV, Guntuku L, Angapelly S, Karri S, Digwal CS, Babu BN, Naidu VGM, Kamal A.

Bioorg Med Chem Lett. 2018 Mar 1;28(5):892-898. doi: 10.1016/j.bmcl.2018.01.070. Epub 2018 Feb 2.

PMID:
29429834
15.

Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens.

Hassan KA, Liu Q, Elbourne LDH, Ahmad I, Sharples D, Naidu V, Chan CL, Li L, Harborne SPD, Pokhrel A, Postis VLG, Goldman A, Henderson PJF, Paulsen IT.

Res Microbiol. 2018 Sep - Oct;169(7-8):450-454. doi: 10.1016/j.resmic.2018.01.001. Epub 2018 Feb 2. Review.

16.

Synthesis, docking, in vitro and in vivo antidiabetic activity of pyrazole-based 2,4-thiazolidinedione derivatives as PPAR-γ modulators.

Naim MJ, Alam O, Alam MJ, Shaquiquzzaman M, Alam MM, Naidu VGM.

Arch Pharm (Weinheim). 2018 Apr;351(3-4):e1700223. doi: 10.1002/ardp.201700223. Epub 2018 Feb 5.

PMID:
29400412
17.

Amelioration of streptozotocin-induced type 2 diabetes mellitus in Wistar rats by arachidonic acid.

Gundala NKV, Naidu VGM, Das UN.

Biochem Biophys Res Commun. 2018 Jan 29;496(1):105-113. doi: 10.1016/j.bbrc.2018.01.007. Epub 2018 Jan 6.

PMID:
29309791
18.

4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.

Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.

Eur J Med Chem. 2018 Jan 20;144:595-611. doi: 10.1016/j.ejmech.2017.12.050. Epub 2017 Dec 14.

PMID:
29289884
19.

Aggressive prostate cancer incidence in New Zealand-"united we fall, divided we stand".

Vaidyanathan V, Karunasinghe N, Krishnamurthy V, Kao CH, Naidu V, Pallati R, Wang A, Tran K, Kallingappa P, Jabed A, Shahid SM, Masters J, Wall C, Narayanan A, Ferguson LR.

N Z Med J. 2017 Dec 1;130(1466):96-99.

PMID:
29197908
20.

Synthesis and biological evaluation of curcumin inspired imidazo[1,2-a]pyridine analogues as tubulin polymerization inhibitors.

Ramya PVS, Guntuku L, Angapelly S, Digwal CS, Lakshmi UJ, Sigalapalli DK, Babu BN, Naidu VGM, Kamal A.

Eur J Med Chem. 2018 Jan 1;143:216-231. doi: 10.1016/j.ejmech.2017.11.010. Epub 2017 Nov 5.

PMID:
29174816
21.

Design, synthesis and molecular docking of thiazolidinedione based benzene sulphonamide derivatives containing pyrazole core as potential anti-diabetic agents.

Naim MJ, Alam O, Alam MJ, Hassan MQ, Siddiqui N, Naidu VGM, Alam MI.

Bioorg Chem. 2018 Feb;76:98-112. doi: 10.1016/j.bioorg.2017.11.010. Epub 2017 Nov 16.

PMID:
29169079
22.

Two uses of the Smillie knife in foot and ankle surgery.

Holme TJ, Mahapatra P, Naidu V.

Ann R Coll Surg Engl. 2018 Apr;100(4):345-346. doi: 10.1308/rcsann.2017.0151. Epub 2017 Sep 13. No abstract available.

23.

Effect of ageing and single nucleotide polymorphisms associated with the risk of aggressive prostate cancer in a New Zealand population.

Vaidyanathan V, Naidu V, Karunasinghe N, Kao CH, Pallati R, Jabed A, Marlow G, Kallingappa P, Ferguson LR.

Mol Biosyst. 2017 Sep 26;13(10):1967-1980. doi: 10.1039/c7mb00203c.

PMID:
28783191
24.

Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-κB and MAPK signalling.

Thummuri D, Naidu VGM, Chaudhari P.

J Mol Med (Berl). 2017 Oct;95(10):1065-1076. doi: 10.1007/s00109-017-1553-1. Epub 2017 Jul 4.

PMID:
28674855
25.

Synthesis of thiazole linked indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors.

Guggilapu SD, Guntuku L, Reddy TS, Nagarsenkar A, Sigalapalli DK, Naidu VGM, Bhargava SK, Bathini NB.

Eur J Med Chem. 2017 Sep 29;138:83-95. doi: 10.1016/j.ejmech.2017.06.025. Epub 2017 Jun 15.

PMID:
28648953
26.

Uridine Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice.

Jeengar MK, Thummuri D, Magnusson M, Naidu VGM, Uppugunduri S.

Sci Rep. 2017 Jun 20;7(1):3924. doi: 10.1038/s41598-017-04041-9.

27.

Preparation, characterization, and cytotoxicity studies of niclosamide loaded mesoporous drug delivery systems.

Pardhi V, Chavan RB, Thipparaboina R, Thatikonda S, Naidu V, Shastri NR.

Int J Pharm. 2017 Aug 7;528(1-2):202-214. doi: 10.1016/j.ijpharm.2017.06.007. Epub 2017 Jun 5. Erratum in: Int J Pharm. 2018 May 1;:.

PMID:
28596138
28.

Synthesis, molecular docking and anti-diabetic evaluation of 2,4-thiazolidinedione based amide derivatives.

Naim MJ, Alam MJ, Nawaz F, Naidu VGM, Aaghaz S, Sahu M, Siddiqui N, Alam O.

Bioorg Chem. 2017 Aug;73:24-36. doi: 10.1016/j.bioorg.2017.05.007. Epub 2017 May 6.

PMID:
28582649
29.

SNP-SNP interactions as risk factors for aggressive prostate cancer.

Vaidyanathan V, Naidu V, Karunasinghe N, Jabed A, Pallati R, Marlow G, R Ferguson L.

F1000Res. 2017 May 3;6:621. doi: 10.12688/f1000research.11027.1. eCollection 2017.

30.

Forced degradation studies of lansoprazole using LC-ESI HRMS and 1 H-NMR experiments: in vitro toxicity evaluation of major degradation products.

Shankar G, Borkar RM, Suresh U, Guntuku L, Naidu VGM, Nagesh N, Srinivas R.

J Mass Spectrom. 2017 Jul;52(7):459-471. doi: 10.1002/jms.3949.

PMID:
28544042
31.

Fast dissolving drug-drug eutectics with improved compressibility and synergistic effects.

Thipparaboina R, Thumuri D, Chavan R, Naidu VGM, Shastri NR.

Eur J Pharm Sci. 2017 Jun 15;104:82-89. doi: 10.1016/j.ejps.2017.03.042. Epub 2017 Mar 31.

PMID:
28366649
32.

Environmental factors and risk of aggressive prostate cancer among a population of New Zealand men - a genotypic approach.

Vaidyanathan V, Naidu V, Kao CH, Karunasinghe N, Bishop KS, Wang A, Pallati R, Shepherd P, Masters J, Zhu S, Goudie M, Krishnan M, Jabed A, Marlow G, Narayanan A, Ferguson LR.

Mol Biosyst. 2017 Mar 28;13(4):681-698. doi: 10.1039/c6mb00873a.

PMID:
28252132
33.

Arachidonic acid and lipoxinA4 attenuate streptozotocin-induced cytotoxicity to RIN5 F cells in vitro and type 1 and type 2 diabetes mellitus in vivo.

Gundala NKV, Naidu VGM, Das UN.

Nutrition. 2017 Mar;35:61-80. doi: 10.1016/j.nut.2016.10.004. Epub 2016 Oct 15.

PMID:
28241993
34.

Real-time imaging as an emerging process analytical technology tool for monitoring of fluid bed coating process.

Naidu VR, Deshpande RS, Syed MR, Wakte PS.

Pharm Dev Technol. 2018 Jul;23(6):596-601. doi: 10.1080/10837450.2017.1287730. Epub 2017 Feb 22.

PMID:
28121263
35.

Gene masking - a technique to improve accuracy for cancer classification with high dimensionality in microarray data.

Saini H, Lal SP, Naidu VV, Pickering VW, Singh G, Tsunoda T, Sharma A.

BMC Med Genomics. 2016 Dec 5;9(Suppl 3):74. doi: 10.1186/s12920-016-0233-2.

36.

Synthesis of 2,3,6,7-tetramethoxyphenanthren-9-amine: An efficient precursor to access new 4-aza-2,3-dihydropyridophenanthrenes as apoptosis inducing agents.

Kumar NP, Sharma P, Reddy TS, Nekkanti S, Shankaraiah N, Lalita G, Sujanakumari S, Bhargava SK, Naidu VGM, Kamal A.

Eur J Med Chem. 2017 Feb 15;127:305-317. doi: 10.1016/j.ejmech.2017.01.001. Epub 2017 Jan 3.

PMID:
28068602
37.

Selective Cascade Reaction of Bisallenes via Palladium-Catalyzed Aerobic Oxidative Carbocyclization-Borylation and Aldehyde Trapping.

Naidu VR, Posevins D, Volla CM, Bäckvall JE.

Angew Chem Int Ed Engl. 2017 Feb 1;56(6):1590-1594. doi: 10.1002/anie.201610524. Epub 2017 Jan 9.

PMID:
28067015
38.

Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors.

Sri Ramya PV, Angapelly S, Guntuku L, Singh Digwal C, Nagendra Babu B, Naidu VGM, Kamal A.

Eur J Med Chem. 2017 Feb 15;127:100-114. doi: 10.1016/j.ejmech.2016.12.043. Epub 2016 Dec 23.

PMID:
28038323
39.

PAT-Based Control of Fluid Bed Coating Process Using NIR Spectroscopy to Monitor the Cellulose Coating on Pharmaceutical Pellets.

Naidu VR, Deshpande RS, Syed MR, Deoghare P, Singh D, Wakte PS.

AAPS PharmSciTech. 2017 Aug;18(6):2045-2054. doi: 10.1208/s12249-016-0680-2. Epub 2016 Dec 19.

PMID:
27995464
40.

Arachidonic acid and lipoxin A4 attenuate alloxan-induced cytotoxicity to RIN5F cells in vitro and type 1 diabetes mellitus in vivo.

Gundala NKV, Naidu VGM, Das UN.

Biofactors. 2017 Mar;43(2):251-271. doi: 10.1002/biof.1336. Epub 2016 Nov 15.

PMID:
27862450
41.

Synthesis and apoptosis inducing studies of triazole linked 3-benzylidene isatin derivatives.

Nagarsenkar A, Guntuku L, Guggilapu SD, K DB, Gannoju S, Naidu VGM, Bathini NB.

Eur J Med Chem. 2016 Nov 29;124:782-793. doi: 10.1016/j.ejmech.2016.09.009. Epub 2016 Sep 4.

PMID:
27639369
42.

Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents.

Sharma P, Srinivasa Reddy T, Thummuri D, Senwar KR, Praveen Kumar N, Naidu VGM, Bhargava SK, Shankaraiah N.

Eur J Med Chem. 2016 Nov 29;124:608-621. doi: 10.1016/j.ejmech.2016.08.029. Epub 2016 Aug 18.

PMID:
27614408
43.

Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.

Shrivastava S, Jeengar MK, Thummuri D, Koval A, Katanaev VL, Marepally S, Naidu VGM.

Biofactors. 2017 Mar;43(2):152-169. doi: 10.1002/biof.1315. Epub 2016 Sep 1.

PMID:
27580587
44.

Polychaete Community of a Marine Protected Area along the West Coast of India-Prior and Post the Tropical Cyclone, Phyan.

Sukumaran S, Vijapure T, Kubal P, Mulik J, Rokade MA, Salvi S, Thomas J, Naidu VS.

PLoS One. 2016 Aug 24;11(8):e0159368. doi: 10.1371/journal.pone.0159368. eCollection 2016.

45.

New (E)-1-alkyl-1H-benzo[d]imidazol-2-yl)methylene)indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies.

Sharma P, Thummuri D, Reddy TS, Senwar KR, Naidu VGM, Srinivasulu G, Bharghava SK, Shankaraiah N.

Eur J Med Chem. 2016 Oct 21;122:584-600. doi: 10.1016/j.ejmech.2016.07.019. Epub 2016 Jul 11.

PMID:
27448916
46.

DABCO-catalyzed one-pot three component synthesis of dihydropyrano[3,2-c]chromene substituted quinazolines and their evaluation towards anticancer activity.

Vodnala S, Bhavani AK, Kamutam R, Naidu VG, Promila, Prabhakar Ch.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):3973-7. doi: 10.1016/j.bmcl.2016.07.003. Epub 2016 Jul 7.

PMID:
27432765
47.

Design and synthesis of 4'-O-alkylamino-tethered-benzylideneindolin-2-ones as potent cytotoxic and apoptosis inducing agents.

Senwar KR, Reddy TS, Thummuri D, Sharma P, Bharghava SK, Naidu VG, Shankaraiah N.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):4061-9. doi: 10.1016/j.bmcl.2016.06.077. Epub 2016 Jun 28.

PMID:
27397498
48.

Synthesis and biological evaluation of oxindole linked indolyl-pyrimidine derivatives as potential cytotoxic agents.

Prajapti SK, Nagarsenkar A, Guggilapu SD, Gupta KK, Allakonda L, Jeengar MK, Naidu VGM, Babu BN.

Bioorg Med Chem Lett. 2016 Jul 1;26(13):3024-3028. doi: 10.1016/j.bmcl.2016.05.019. Epub 2016 May 7.

PMID:
27210438
49.

Amelioration of FCA induced arthritis on topical application of curcumin in combination with emu oil.

Jeengar MK, Shrivastava S, Mouli Veeravalli SC, Naidu VG, Sistla R.

Nutrition. 2016 Sep;32(9):955-64. doi: 10.1016/j.nut.2016.02.009. Epub 2016 Mar 8.

PMID:
27178879
50.

Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents.

Senwar KR, Reddy TS, Thummuri D, Sharma P, Naidu VG, Srinivasulu G, Shankaraiah N.

Eur J Med Chem. 2016 Aug 8;118:34-46. doi: 10.1016/j.ejmech.2016.04.025. Epub 2016 Apr 11.

PMID:
27128173

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