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Items: 1 to 50 of 232

1.

The Synthesis of Sulfated CCR5 Peptide Surrogates and their Use to Study Receptor-Ligand Interactions.

Naider F, Anglister J.

Protein Pept Lett. 2018;25(12):1124-1136. doi: 10.2174/0929866525666181101103834. Review.

PMID:
30381052
2.

Defining specific residue-to-residue interactions between the gp120 bridging sheet and the N-terminal segment of CCR5: applications of transferred NOE NMR.

Srivastava G, Moseri A, Kessler N, Arshava B, Naider F, Anglister J.

FEBS J. 2018 Nov;285(22):4296-4310. doi: 10.1111/febs.14673. Epub 2018 Oct 20.

PMID:
30288935
3.

Effects of chelator lipids, paramagnetic metal ions and trehalose on liposomes by solid-state NMR.

Lam D, Zhuang J, Cohen LS, Arshava B, Naider FR, Tang M.

Solid State Nucl Magn Reson. 2018 Oct;94:1-6. doi: 10.1016/j.ssnmr.2018.07.002. Epub 2018 Jul 27.

PMID:
30096558
4.

The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5.

Abayev M, Rodrigues JPGLM, Srivastava G, Arshava B, Jaremko Ł, Jaremko M, Naider F, Levitt M, Anglister J.

FEBS J. 2018 Jun;285(11):1988-2003. doi: 10.1111/febs.14460. Epub 2018 Apr 20.

5.

Uptake Assay for Radiolabeled Peptides in Yeast.

Hauser M, Cai H, Naider F, Becker JM.

Bio Protoc. 2016 Nov 20;6(22). pii: e2026. doi: 10.21769/BioProtoc.2026.

6.

Identification of peptide-binding sites within BSA using rapid, laser-induced covalent cross-linking combined with high-performance mass spectrometry.

Hauser M, Qian C, King ST, Kauffman S, Naider F, Hettich RL, Becker JM.

J Mol Recognit. 2018 Feb;31(2). doi: 10.1002/jmr.2680. Epub 2017 Oct 10.

7.

Dynamic roles for the N-terminus of the yeast G protein-coupled receptor Ste2p.

Uddin MS, Naider F, Becker JM.

Biochim Biophys Acta Biomembr. 2017 Oct;1859(10):2058-2067. doi: 10.1016/j.bbamem.2017.07.014. Epub 2017 Jul 25.

8.

Halo Assay for Toxic Peptides and Other Compounds in Microorganisms.

Cai H, Hauser M, Naider F, Becker JM.

Bio Protoc. 2016 Nov 20;6(22). pii: e2025. doi: 10.21769/BioProtoc.2025.

9.

Detection of intermolecular transferred-NOE interactions in small and medium size protein complexes: RANTES complexed with a CCR5 N-terminal peptide.

Abayev M, Srivastava G, Arshava B, Naider F, Anglister J.

FEBS J. 2017 Feb;284(4):586-601. doi: 10.1111/febs.14000. Epub 2017 Jan 24.

10.

Immunofocusing using conformationally constrained V3 peptide immunogens improves HIV-1 neutralization.

Moseri A, Sinha E, Zommer H, Arshava B, Naider F, Anglister J.

Vaccine. 2017 Jan 5;35(2):222-230. doi: 10.1016/j.vaccine.2016.11.088. Epub 2016 Dec 7.

PMID:
27939012
11.

Detection of intermolecular NOE interactions in large protein complexes.

Anglister J, Srivastava G, Naider F.

Prog Nucl Magn Reson Spectrosc. 2016 Nov;97:40-56. doi: 10.1016/j.pnmrs.2016.08.002. Epub 2016 Aug 18. Review.

PMID:
27888839
12.

NMR Investigation of Structures of G-protein Coupled Receptor Folding Intermediates.

Poms M, Ansorge P, Martinez-Gil L, Jurt S, Gottstein D, Fracchiolla KE, Cohen LS, Güntert P, Mingarro I, Naider F, Zerbe O.

J Biol Chem. 2016 Dec 30;291(53):27170-27186. doi: 10.1074/jbc.M116.740985. Epub 2016 Nov 18.

13.

Detection of intermolecular transferred NOEs in large protein complexes using asymmetric deuteration: HIV-1 gp120 in complex with a CCR5 peptide.

Srivastava G, Moseri A, Kessler N, Akabayov SR, Arshava B, Naider F, Anglister J.

FEBS J. 2016 Nov;283(22):4084-4096. doi: 10.1111/febs.13916. Epub 2016 Oct 23.

14.

Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein-coupled Receptor in Yeast.

Sridharan R, Connelly SM, Naider F, Dumont ME.

J Biol Chem. 2016 Nov 11;291(46):24261-24279. Epub 2016 Sep 19.

15.

The N-terminus of the yeast G protein-coupled receptor Ste2p plays critical roles in surface expression, signaling, and negative regulation.

Uddin MS, Hauser M, Naider F, Becker JM.

Biochim Biophys Acta. 2016 Apr;1858(4):715-24. doi: 10.1016/j.bbamem.2015.12.017. Epub 2015 Dec 17.

16.

The C4 region as a target for HIV entry inhibitors--NMR mapping of the interacting segments of T20 and gp120.

Moseri A, Biron Z, Arshava B, Scherf T, Naider F, Anglister J.

FEBS J. 2015 Dec;282(24):4643-57. doi: 10.1111/febs.13541. Epub 2015 Oct 22.

17.

Cross-linking strategies to study peptide ligand-receptor interactions.

Becker JM, Naider F.

Methods Enzymol. 2015;556:527-47. doi: 10.1016/bs.mie.2014.12.001. Epub 2015 Mar 20.

PMID:
25857798
18.

An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions.

Abayev M, Moseri A, Tchaicheeyan O, Kessler N, Arshava B, Naider F, Scherf T, Anglister J.

FEBS J. 2015 May;282(10):1906-1921. doi: 10.1111/febs.13243. Epub 2015 Mar 18.

19.

Identification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae.

Zuber J, Danial SA, Connelly SM, Naider F, Dumont ME.

Biochemistry. 2015 Mar 10;54(9):1787-806. doi: 10.1021/bi501314t. Epub 2015 Feb 24.

20.

Structural characterization of triple transmembrane domain containing fragments of a yeast G protein-coupled receptor in an organic : aqueous environment by solution-state NMR spectroscopy.

Fracchiolla KE, Cohen LS, Arshava B, Poms M, Zerbe O, Becker JM, Naider F.

J Pept Sci. 2015 Mar;21(3):212-22. doi: 10.1002/psc.2750. Epub 2015 Feb 2.

21.

Novobiocin and peptide analogs of α-factor are positive allosteric modulators of the yeast G protein-coupled receptor Ste2p.

Rymer JK, Hauser M, Bourdon AK, Campagna SR, Naider F, Becker JM.

Biochim Biophys Acta. 2015 Apr;1848(4):916-24. doi: 10.1016/j.bbamem.2014.12.024. Epub 2015 Jan 7.

22.

NMR observation of HIV-1 gp120 conformational flexibility resulting from V3 truncation.

Moseri A, Schnur E, Noah E, Zherdev Y, Kessler N, Singhal Sinha E, Abayev M, Naider F, Scherf T, Anglister J.

FEBS J. 2014 Jul;281(13):3019-31. doi: 10.1111/febs.12839. Epub 2014 Jun 3.

23.

Invited review: GPCR structural characterization: Using fragments as building blocks to determine a complete structure.

Cohen LS, Fracchiolla KE, Becker J, Naider F.

Biopolymers. 2014 May;102(3):223-43. doi: 10.1002/bip.22490. Review.

PMID:
24687329
24.

Guided reconstitution of membrane protein fragments.

Cohen LS, Arshava B, Kauffman S, Mathew E, Fracchiolla KE, Ding FX, Dumont ME, Becker JM, Naider F.

Biopolymers. 2014 Jan;102(1):16-29. doi: 10.1002/bip.22349.

25.

NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains.

Schnur E, Kessler N, Zherdev Y, Noah E, Scherf T, Ding FX, Rabinovich S, Arshava B, Kurbatska V, Leonciks A, Tsimanis A, Rosen O, Naider F, Anglister J.

FEBS J. 2013 May;280(9):2068-84. doi: 10.1111/febs.12230. Epub 2013 Apr 2.

26.

Large multiple transmembrane domain fragments of a G protein-coupled receptor: biosynthesis, purification, and biophysical studies.

Potetinova Z, Tantry S, Cohen LS, Caroccia KE, Arshava B, Becker JM, Naider F.

Biopolymers. 2012;98(5):485-500. doi: 10.1002/bip.22122.

27.

Synergism between a CD4-mimic peptide and antibodies elicited by a constrained V3 peptide.

Moseri A, Tantry S, Ding FX, Naider F, Anglister J.

AIDS Res Hum Retroviruses. 2013 Apr;29(4):718-24. doi: 10.1089/AID.2012.0189. Epub 2012 Dec 26.

28.

Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.

Mathew E, Ding FX, Naider F, Dumont ME.

Protein Eng Des Sel. 2013 Jan;26(1):59-71. doi: 10.1093/protein/gzs070. Epub 2012 Oct 16.

29.

Comparison of fragments comprising the first two helices of the human Y4 and the yeast Ste2p G-protein-coupled receptors.

Shao X, Zou C, Naider F, Zerbe O.

Biophys J. 2012 Aug 22;103(4):817-26. doi: 10.1016/j.bpj.2012.07.012.

30.

Identification of residues involved in homodimer formation located within a β-strand region of the N-terminus of a Yeast G protein-coupled receptor.

Uddin MS, Kim H, Deyo A, Naider F, Becker JM.

J Recept Signal Transduct Res. 2012 Apr;32(2):65-75. doi: 10.3109/10799893.2011.647352. Epub 2012 Jan 24.

PMID:
22268895
31.

Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR.

Kim KM, Lee YH, Akal-Strader A, Uddin MS, Hauser M, Naider F, Becker JM.

Pharmacol Res. 2012 Jan;65(1):31-40. doi: 10.1016/j.phrs.2011.11.002. Epub 2011 Nov 10.

32.

A solution NMR view of protein dynamics in the biological membrane.

Chill JH, Naider F.

Curr Opin Struct Biol. 2011 Oct;21(5):627-33. doi: 10.1016/j.sbi.2011.07.003. Epub 2011 Jul 30. Review.

PMID:
21807499
33.

Comparative NMR analysis of an 80-residue G protein-coupled receptor fragment in two membrane mimetic environments.

Cohen LS, Arshava B, Neumoin A, Becker JM, Güntert P, Zerbe O, Naider F.

Biochim Biophys Acta. 2011 Nov;1808(11):2674-84. doi: 10.1016/j.bbamem.2011.07.011. Epub 2011 Jul 23.

34.

The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide.

Schnur E, Noah E, Ayzenshtat I, Sargsyan H, Inui T, Ding FX, Arshava B, Sagi Y, Kessler N, Levy R, Scherf T, Naider F, Anglister J.

J Mol Biol. 2011 Jul 29;410(5):778-97. doi: 10.1016/j.jmb.2011.04.023. Erratum in: J Mol Biol. 2012 Apr 20;418(1-2):127.

35.

Changes in conformation at the cytoplasmic ends of the fifth and sixth transmembrane helices of a yeast G protein-coupled receptor in response to ligand binding.

Umanah GK, Huang LY, Maccarone JM, Naider F, Becker JM.

Biochemistry. 2011 Aug 16;50(32):6841-54. doi: 10.1021/bi200254h. Epub 2011 Jul 12.

36.

Expression and biophysical analysis of a triple-transmembrane domain-containing fragment from a yeast G protein-coupled receptor.

Caroccia KE, Estephan R, Cohen LS, Arshava B, Hauser M, Zerbe O, Becker JM, Naider F.

Biopolymers. 2011;96(6):757-71. doi: 10.1002/bip.21614.

PMID:
21695690
37.

Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p.

Mathew E, Bajaj A, Connelly SM, Sargsyan H, Ding FX, Hajduczok AG, Naider F, Dumont ME.

J Mol Biol. 2011 Jun 17;409(4):513-28. doi: 10.1016/j.jmb.2011.03.059. Epub 2011 Apr 6.

38.

Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology.

Mullen DG, Kyro K, Hauser M, Gustavsson M, Veglia G, Becker JM, Naider F, Distefano MD.

Bioorg Med Chem. 2011 Jan 1;19(1):490-7. doi: 10.1016/j.bmc.2010.11.006. Epub 2010 Nov 12.

39.

Identification of residue-to-residue contact between a peptide ligand and its G protein-coupled receptor using periodate-mediated dihydroxyphenylalanine cross-linking and mass spectrometry.

Umanah GK, Huang L, Ding FX, Arshava B, Farley AR, Link AJ, Naider F, Becker JM.

J Biol Chem. 2010 Dec 10;285(50):39425-36. doi: 10.1074/jbc.M110.149500. Epub 2010 Oct 4.

40.
41.

Biosynthesis of peptide fragments of eukaryotic GPCRs in Escherichia coli by directing expression into inclusion bodies.

Cohen LS, Becker JM, Naider F.

J Pept Sci. 2010 May;16(5):213-8. doi: 10.1002/psc.1222.

PMID:
20401922
42.

An optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120.

Moseri A, Tantry S, Sagi Y, Arshava B, Naider F, Anglister J.

Virology. 2010 Jun 5;401(2):293-304. doi: 10.1016/j.virol.2010.03.007. Epub 2010 Mar 26.

43.
44.

Peptides in the treatment of AIDS.

Naider F, Anglister J.

Curr Opin Struct Biol. 2009 Aug;19(4):473-82. doi: 10.1016/j.sbi.2009.07.003. Epub 2009 Jul 23. Review.

45.

HIV-1 peptide vaccine candidates: selecting constrained V3 peptides with highest affinity to antibody 447-52D.

Mester B, Manor R, Mor A, Arshava B, Rosen O, Ding FX, Naider F, Anglister J.

Biochemistry. 2009 Aug 25;48(33):7867-77. doi: 10.1021/bi900146g.

PMID:
19552398
46.

Incorporation of the unnatural amino acid p-benzoyl-L-phenylalanine (Bpa) into a G protein-coupled receptor in its native context.

Umanah G, Huang LY, Schultz PG, Naider F, Becker JM.

Adv Exp Med Biol. 2009;611:333-5. No abstract available.

PMID:
19400216
47.

Structural studies on large fragments of G protein coupled receptors.

Naider F, Neumoin A, Arshava B, Cohen LS, Becker JM, Zerbe O.

Adv Exp Med Biol. 2009;611:309-10. No abstract available.

PMID:
19400205
48.

Expression of double transmembrane domain GPCR fragments for biophysical analysis.

Cohen LS, Arshava B, Estephan R, Englander J, Hauser M, Becker JM, Naider F.

Adv Exp Med Biol. 2009;611:303-4. No abstract available.

PMID:
19400203
49.

Structure of a double transmembrane fragment of a G-protein-coupled receptor in micelles.

Neumoin A, Cohen LS, Arshava B, Tantry S, Becker JM, Zerbe O, Naider F.

Biophys J. 2009 Apr 22;96(8):3187-96. doi: 10.1016/j.bpj.2009.01.012.

50.

Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies.

Mor A, Segal E, Mester B, Arshava B, Rosen O, Ding FX, Russo J, Dafni A, Schvartzman F, Scherf T, Naider F, Anglister J.

Biochemistry. 2009 Apr 21;48(15):3288-303. doi: 10.1021/bi802308n.

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