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Items: 1 to 50 of 268

1.

Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.

Liu CL, Zhang X, Liu J, Wang Y, Sukhova GK, Wojtkiewicz GR, Liu T, Tang R, Achilefu S, Nahrendorf M, Libby P, Guo J, Zhang JY, Shi GP.

Nat Commun. 2019 Sep 4;10(1):3978. doi: 10.1038/s41467-019-11983-3.

2.

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.

Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM.

Sci Transl Med. 2019 Aug 21;11(506). pii: eaaw7736. doi: 10.1126/scitranslmed.aaw7736.

PMID:
31434756
3.

Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.

Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT.

Cell Stem Cell. 2019 Jun 26. pii: S1934-5909(19)30267-X. doi: 10.1016/j.stem.2019.06.003. [Epub ahead of print]

PMID:
31279774
4.

Stress-Associated Neurobiological Pathway Linking Socioeconomic Disparities to Cardiovascular Disease.

Tawakol A, Osborne MT, Wang Y, Hammed B, Tung B, Patrich T, Oberfeld B, Ishai A, Shin LM, Nahrendorf M, Warner ET, Wasfy J, Fayad ZA, Koenen K, Ridker PM, Pitman RK, Armstrong KA.

J Am Coll Cardiol. 2019 Jul 2;73(25):3243-3255. doi: 10.1016/j.jacc.2019.04.042.

PMID:
31248544
5.

Smad3 Cranks Up the Appetite of Infarct Macrophages.

Hulsmans M, Nahrendorf M.

Circ Res. 2019 Jun 21;125(1):71-73. doi: 10.1161/CIRCRESAHA.119.315306. Epub 2019 Jun 20. No abstract available.

PMID:
31219739
6.

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.

Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O.

J Am Coll Cardiol. 2019 Jun 18;73(23):2990-3002. doi: 10.1016/j.jacc.2019.03.503.

7.

Clonal and diverse: revisiting cardiac endothelial cells after myocardial infarction.

Rohde D, Nahrendorf M.

Eur Heart J. 2019 Aug 7;40(30):2521-2522. doi: 10.1093/eurheartj/ehz375. No abstract available.

PMID:
31162523
8.

Interferon-ɣ regulates cardiac myeloid cells in myocardial infarction.

Hoyer FF, Nahrendorf M.

Cardiovasc Res. 2019 Jun 4. pii: cvz143. doi: 10.1093/cvr/cvz143. [Epub ahead of print] No abstract available.

PMID:
31161218
9.

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo.

Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11966-11971. doi: 10.1073/pnas.1818434116. Epub 2019 May 23.

PMID:
31123149
10.

Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R.

Nat Biomed Eng. 2018 Aug;2(8):623. doi: 10.1038/s41551-018-0281-3.

PMID:
31015637
11.

Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction.

Leuschner F, Nahrendorf M.

Eur Heart J. 2019 Mar 3. pii: ehz159. doi: 10.1093/eurheartj/ehz159. [Epub ahead of print]

PMID:
30945736
12.

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R.

Nat Biomed Eng. 2018 May;2(5):279-292. doi: 10.1038/s41551-018-0221-2. Epub 2018 Apr 16. Erratum in: Nat Biomed Eng. 2018 Aug;2(8):623.

13.

Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke.

Courties G, Frodermann V, Honold L, Zheng Y, Herisson F, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden DT, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M.

Circ Res. 2019 Apr 26;124(9):1372-1385. doi: 10.1161/CIRCRESAHA.118.314518.

PMID:
30782088
14.

Sleep modulates haematopoiesis and protects against atherosclerosis.

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb 13.

15.

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.

He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK.

Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30.

16.

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.

Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Santos Masson G, Tesmenitsky Y, Folco E, Gram H, Nahrendorf M, Swirski FK, Sukhova GK, Libby P.

Eur Heart J. 2019 Aug 7;40(30):2482-2491. doi: 10.1093/eurheartj/ehz008.

PMID:
30698710
17.

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK.

J Exp Med. 2019 Feb 4;216(2):369-383. doi: 10.1084/jem.20180722. Epub 2019 Jan 22.

18.

A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart.

Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre AD, Nahrendorf M, Weissleder R.

Bioconjug Chem. 2019 Mar 20;30(3):733-740. doi: 10.1021/acs.bioconjchem.8b00882. Epub 2019 Jan 18.

19.

Uremic Toxins Activate Macrophages.

Hoyer FF, Nahrendorf M.

Circulation. 2019 Jan 2;139(1):97-100. doi: 10.1161/CIRCULATIONAHA.118.037308. No abstract available.

PMID:
30592654
20.

Myeloid cells in cardiovascular organs.

Nahrendorf M.

J Intern Med. 2019 May;285(5):491-502. doi: 10.1111/joim.12844. Epub 2018 Dec 25.

PMID:
30585362
21.

A Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse.

Hulsmans M, Aguirre AD, Bonner MD, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M.

Circ Res. 2018 Nov 9;123(11):1208-1219. doi: 10.1161/CIRCRESAHA.118.313429.

PMID:
30571465
22.

Reply to 'Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies'.

Swirski FK, Nahrendorf M.

Nat Rev Immunol. 2019 Jan;19(1):65. doi: 10.1038/s41577-018-0099-y. No abstract available.

PMID:
30552386
23.

Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin.

Kim HY, Li R, Ng TSC, Courties G, Rodell CB, Prytyskach M, Kohler RH, Pittet MJ, Nahrendorf M, Weissleder R, Miller MA.

ACS Nano. 2018 Dec 26;12(12):12015-12029. doi: 10.1021/acsnano.8b04338. Epub 2018 Dec 11.

24.

IL-1β Inhibition Reduces Atherosclerotic Inflammation in HIV Infection.

Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A.

J Am Coll Cardiol. 2018 Dec 4;72(22):2809-2811. doi: 10.1016/j.jacc.2018.09.038. No abstract available.

PMID:
30497570
25.

Multiorgan Imaging of Comorbidity and Cardiovascular Risk.

Nahrendorf M.

JACC Cardiovasc Imaging. 2018 Nov 8. pii: S1936-878X(18)30919-7. doi: 10.1016/j.jcmg.2018.09.017. [Epub ahead of print] No abstract available.

PMID:
30448129
26.

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.

Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J.

Immunity. 2018 Nov 20;49(5):819-828.e6. doi: 10.1016/j.immuni.2018.09.008. Epub 2018 Nov 6.

PMID:
30413362
27.

Cardioimmunology: the immune system in cardiac homeostasis and disease.

Swirski FK, Nahrendorf M.

Nat Rev Immunol. 2018 Dec;18(12):733-744. doi: 10.1038/s41577-018-0065-8. Review.

PMID:
30228378
28.

Nanoimmunotherapy to treat ischaemic heart disease.

Duivenvoorden R, Senders ML, van Leent MMT, Pérez-Medina C, Nahrendorf M, Fayad ZA, Mulder WJM.

Nat Rev Cardiol. 2019 Jan;16(1):21-32. doi: 10.1038/s41569-018-0073-1. Review.

PMID:
30209355
29.

Macrophages and Cardiovascular Health.

Frodermann V, Nahrendorf M.

Physiol Rev. 2018 Oct 1;98(4):2523-2569. doi: 10.1152/physrev.00068.2017. Review.

PMID:
30156496
30.

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration.

Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Masson GS, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M.

Nat Neurosci. 2018 Sep;21(9):1209-1217. doi: 10.1038/s41593-018-0213-2. Epub 2018 Aug 27.

31.

Some Macrophages Are Softies.

Schloss MJ, Nahrendorf M.

Immunity. 2018 Aug 21;49(2):199-201. doi: 10.1016/j.immuni.2018.08.007.

32.

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress.

Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz G, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson F, Jung Y, Désogère PA, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M.

Circ Res. 2018 Aug 3;123(4):415-427. doi: 10.1161/CIRCRESAHA.118.313302.

33.

The human heart contains distinct macrophage subsets with divergent origins and functions.

Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ.

Nat Med. 2018 Aug;24(8):1234-1245. doi: 10.1038/s41591-018-0059-x. Epub 2018 Jun 11.

34.

Myeloid cell contributions to cardiovascular health and disease.

Nahrendorf M.

Nat Med. 2018 Jun;24(6):711-720. doi: 10.1038/s41591-018-0064-0. Epub 2018 Jun 4. Review.

PMID:
29867229
35.

Myeloid Cells Remodel the Mitral Valve.

Cremer S, Nahrendorf M.

Circulation. 2018 Jun 5;137(23):2494-2496. doi: 10.1161/CIRCULATIONAHA.118.033622. No abstract available. Erratum in: Circulation. 2018 Aug 7;138(6):e125.

36.

Clonal Hematopoiesis Wages War on the Myocardium.

Swirski FK, Nahrendorf M.

J Am Coll Cardiol. 2018 Feb 27;71(8):887-889. doi: 10.1016/j.jacc.2017.12.038. No abstract available.

37.

Correlation of 360-degree Surface Mapping In Vivo Bioluminescence with Multi-Spectral Optoacoustic Tomography in Human Xenograft Tumor Models.

Brannen A, Eggert M, Nahrendorf M, Arnold R, Panizzi P.

Sci Rep. 2018 Feb 20;8(1):3321. doi: 10.1038/s41598-018-21668-4.

38.

Albumin-Binding MR Probe Detects High-Risk Coronary Plaques in Patients.

Nahrendorf M, Vandoorne K.

JACC Cardiovasc Imaging. 2019 Feb;12(2):307-309. doi: 10.1016/j.jcmg.2017.11.026. Epub 2018 Jan 17. No abstract available.

PMID:
29361477
39.

Cardiac macrophages promote diastolic dysfunction.

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.

J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16.

40.

Increased Left Ventricular Filling Pressure and Arterial Occlusion in Stroke Related to Atrial Fibrillation.

Ryu WS, Bae EK, Park SH, Jeong SW, Schellingerhout D, Nahrendorf M, Kim DE.

J Stroke Cerebrovasc Dis. 2018 May;27(5):1275-1282. doi: 10.1016/j.jstrokecerebrovasdis.2017.12.009. Epub 2018 Jan 5.

PMID:
29310958
41.

Resident and Monocyte-Derived Macrophages in Cardiovascular Disease.

Honold L, Nahrendorf M.

Circ Res. 2018 Jan 5;122(1):113-127. doi: 10.1161/CIRCRESAHA.117.311071. Review.

42.

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils.

Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ.

Science. 2017 Dec 1;358(6367). pii: eaal5081. doi: 10.1126/science.aal5081.

43.

CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease.

Verweij SL, Duivenvoorden R, Stiekema LCA, Nurmohamed NS, van der Valk FM, Versloot M, Verberne HJ, Stroes ESG, Nahrendorf M, Bekkering S, Bernelot Moens SJ.

Cardiovasc Res. 2018 Mar 1;114(3):468-475. doi: 10.1093/cvr/cvx224.

PMID:
29186373
44.

IRF3 and type I interferons fuel a fatal response to myocardial infarction.

King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP Jr, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R.

Nat Med. 2017 Dec;23(12):1481-1487. doi: 10.1038/nm.4428. Epub 2017 Nov 6.

45.

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard BG, Neidhart M, Stroes ESG, Catapano AL, Bekkering S.

Eur Heart J. 2018 Oct 7;39(38):3521-3527. doi: 10.1093/eurheartj/ehx581. Erratum in: Eur Heart J. 2018 Jun 14;39(23):2182.

46.

Integrating nanomedicine and imaging.

Pérez-Medina C, Hak S, Reiner T, Fayad ZA, Nahrendorf M, Mulder WJM.

Philos Trans A Math Phys Eng Sci. 2017 Nov 28;375(2107). pii: 20170110. doi: 10.1098/rsta.2017.0110. Review.

47.

The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.

Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK.

J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4.

48.

Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice.

Shon SM, Jang HJ, Schellingerhout D, Kim JY, Ryu WS, Lee SK, Kim J, Park JY, Oh JH, Kang JW, Je KH, Park JE, Kim K, Kwon IC, Lee J, Nahrendorf M, Park JH, Kim DE.

Circ J. 2017 Sep 25;81(10):1528-1536. doi: 10.1253/circj.CJ-16-1196. Epub 2017 Sep 5.

49.

Unraveling Vascular Inflammation: From Immunology to Imaging.

Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN.

J Am Coll Cardiol. 2017 Sep 12;70(11):1403-1412. doi: 10.1016/j.jacc.2017.07.750. Review.

50.

The maturation of a 'neural-hematopoietic' inflammatory axis in cardiovascular disease.

Stiekema LCA, Schnitzler JG, Nahrendorf M, Stroes ESG.

Curr Opin Lipidol. 2017 Dec;28(6):507-512. doi: 10.1097/MOL.0000000000000457. Review.

PMID:
28877089

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