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Items: 22

1.

PLIF: A rapid, accurate method to detect and quantitatively assess protein-lipid interactions.

Ceccato L, Chicanne G, Nahoum V, Pons V, Payrastre B, Gaits-Iacovoni F, Viaud J.

Sci Signal. 2016 Mar 29;9(421):rs2. doi: 10.1126/scisignal.aad4337.

PMID:
27025878
2.

Probing the Functions of Carbohydrate Binding Modules in the CBEL Protein from the Oomycete Phytophthora parasitica.

Martinez T, Texier H, Nahoum V, Lafitte C, Cioci G, Heux L, Dumas B, O'Donohue M, Gaulin E, Dumon C.

PLoS One. 2015 Sep 21;10(9):e0137481. doi: 10.1371/journal.pone.0137481. eCollection 2015.

3.

New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.

Gros C, Fleury L, Nahoum V, Faux C, Valente S, Labella D, Cantagrel F, Rilova E, Bouhlel MA, David-Cordonnier MH, Dufau I, Ausseil F, Mai A, Mourey L, Lacroix L, Arimondo PB.

J Biol Chem. 2015 Mar 6;290(10):6293-302. doi: 10.1074/jbc.M114.594671. Epub 2014 Dec 18.

4.

The high resolution structure of tyrocidine A reveals an amphipathic dimer.

Loll PJ, Upton EC, Nahoum V, Economou NJ, Cocklin S.

Biochim Biophys Acta. 2014 May;1838(5):1199-207. doi: 10.1016/j.bbamem.2014.01.033. Epub 2014 Feb 11.

5.

First structural insights into α-L-arabinofuranosidases from the two GH62 glycoside hydrolase subfamilies.

Siguier B, Haon M, Nahoum V, Marcellin M, Burlet-Schiltz O, Coutinho PM, Henrissat B, Mourey L, O'Donohue MJ, Berrin JG, Tranier S, Dumon C.

J Biol Chem. 2014 Feb 21;289(8):5261-73. doi: 10.1074/jbc.M113.528133. Epub 2014 Jan 6.

6.

A carrier protein strategy yields the structure of dalbavancin.

Economou NJ, Nahoum V, Weeks SD, Grasty KC, Zentner IJ, Townsend TM, Bhuiya MW, Cocklin S, Loll PJ.

J Am Chem Soc. 2012 Mar 14;134(10):4637-45. doi: 10.1021/ja208755j. Epub 2012 Mar 1.

7.

Structure of ristocetin A in complex with a bacterial cell-wall mimetic.

Nahoum V, Spector S, Loll PJ.

Acta Crystallogr D Biol Crystallogr. 2009 Aug;65(Pt 8):832-8. doi: 10.1107/S0907444909018344. Epub 2009 Jul 17. Erratum in: Acta Crystallogr D Biol Crystallogr. 2011 Jun;67(Pt 6):592.

8.

Nuclear receptor ligand-binding domains: reduction of helix H12 dynamics to favour crystallization.

Nahoum V, Lipski A, Quillard F, Guichou JF, Boublik Y, Pérez E, Germain P, de Lera AR, Bourguet W.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jul 1;64(Pt 7):614-6. doi: 10.1107/S1744309108015492. Epub 2008 Jun 11.

9.

N-1H-benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonists.

Benod C, Subra G, Nahoum V, Mallavialle A, Guichou JF, Milhau J, Roblés S, Bourguet W, Pascussi JM, Balaguer P, Chavanieu A.

Bioorg Med Chem. 2008 Apr 1;16(7):3537-49. doi: 10.1016/j.bmc.2008.02.020. Epub 2008 Feb 13.

PMID:
18304819
10.

Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function.

Nahoum V, Pérez E, Germain P, Rodríguez-Barrios F, Manzo F, Kammerer S, Lemaire G, Hirsch O, Royer CA, Gronemeyer H, de Lera AR, Bourguet W.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8. Epub 2007 Oct 18.

11.

Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity.

Lemaire G, Benod C, Nahoum V, Pillon A, Boussioux AM, Guichou JF, Subra G, Pascussi JM, Bourguet W, Chavanieu A, Balaguer P.

Mol Pharmacol. 2007 Sep;72(3):572-81. Epub 2007 Jun 15.

PMID:
17573484
12.

Androgen and estrogen receptors: potential of crystallography in the fight against cancer.

Nahoum V, Bourguet W.

Int J Biochem Cell Biol. 2007;39(7-8):1280-7. Epub 2007 Jan 20. Review.

PMID:
17300979
13.

Molecular basis of the effects of chloride ion on the acid-base catalyst in the mechanism of pancreatic alpha-amylase.

Qian M, Ajandouz el H, Payan F, Nahoum V.

Biochemistry. 2005 Mar 8;44(9):3194-201.

PMID:
15736930
14.

Protein crystal growth on board Shenzhou 3: a concerted effort improves crystal diffraction quality and facilitates structure determination.

Han Y, Cang HX, Zhou JX, Wang YP, Bi RC, Colelesage J, Delbaere LT, Nahoum V, Shi R, Zhou M, Zhu DW, Lin SX.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):1081-6.

PMID:
15485665
15.

How estrogen-specific proteins discriminate estrogens from androgens: a common steroid binding site architecture.

Nahoum V, Gangloff A, Shi R, Lin SX.

FASEB J. 2003 Jul;17(10):1334-6. Epub 2003 May 20.

PMID:
12759331
16.
17.

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

Nahoum V, Gangloff A, Legrand P, Zhu DW, Cantin L, Zhorov BS, Luu-The V, Labrie F, Breton R, Lin SX.

J Biol Chem. 2001 Nov 9;276(45):42091-8. Epub 2001 Aug 20.

18.

Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High-resolution structural analysis of an enzyme-inhibitor complex.

Qian M, Nahoum V, Bonicel J, Bischoff H, Henrissat B, Payan F.

Biochemistry. 2001 Jun 26;40(25):7700-9.

PMID:
11412124
19.

Crystallization and preliminary X-ray crystallographic analysis of the human type 3 3 alpha-hydroxysteroid dehydrogenase at 1.8 A resolution.

Zhu DW, Cantin L, Nahoum V, Rehse P, Luu-The V, Labrie F, Breton R, Lin SX.

Acta Crystallogr D Biol Crystallogr. 2001 Apr;57(Pt 4):589-91.

PMID:
11264591
20.

Crystallization and preliminary X-ray diffraction analysis of the chloramphenicol acetyltransferase from Tn2424.

Zhou M, Lu ML, Qiu W, Campbell RL, Nahoum V, Lapointe J, Roy PH, Lin SX.

Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):281-3.

PMID:
11173480
21.

Crystal structures of human pancreatic alpha-amylase in complex with carbohydrate and proteinaceous inhibitors.

Nahoum V, Roux G, Anton V, Rougé P, Puigserver A, Bischoff H, Henrissat B, Payan F.

Biochem J. 2000 Feb 15;346 Pt 1:201-8.

22.

A plant-seed inhibitor of two classes of alpha-amylases: X-ray analysis of Tenebrio molitor larvae alpha-amylase in complex with the bean Phaseolus vulgaris inhibitor.

Nahoum V, Farisei F, Le-Berre-Anton V, Egloff MP, Rougé P, Poerio E, Payan F.

Acta Crystallogr D Biol Crystallogr. 1999 Jan;55(Pt 1):360-2. Epub 1999 Jan 1.

PMID:
10089450

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