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Items: 6

1.

Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.

Prukova D, Andera L, Nahacka Z, Karolova J, Svaton M, Klanova M, Havranek O, Soukup J, Svobodova K, Zemanova Z, Tuskova D, Pokorna E, Helman K, Forsterova K, Pacheco-Blanco M, Vockova P, Berkova A, Fronkova E, Trneny M, Klener P.

Clin Cancer Res. 2019 Jul 15;25(14):4455-4465. doi: 10.1158/1078-0432.CCR-18-3275. Epub 2019 Apr 19.

PMID:
31004002
2.

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.

Bajzikova M, Kovarova J, Coelho AR, Boukalova S, Oh S, Rohlenova K, Svec D, Hubackova S, Endaya B, Judasova K, Bezawork-Geleta A, Kluckova K, Chatre L, Zobalova R, Novakova A, Vanova K, Ezrova Z, Maghzal GJ, Magalhaes Novais S, Olsinova M, Krobova L, An YJ, Davidova E, Nahacka Z, Sobol M, Cunha-Oliveira T, Sandoval-Acuña C, Strnad H, Zhang T, Huynh T, Serafim TL, Hozak P, Sardao VA, Koopman WJH, Ricchetti M, Oliveira PJ, Kolar F, Kubista M, Truksa J, Dvorakova-Hortova K, Pacak K, Gurlich R, Stocker R, Zhou Y, Berridge MV, Park S, Dong L, Rohlena J, Neuzil J.

Cell Metab. 2019 Feb 5;29(2):399-416.e10. doi: 10.1016/j.cmet.2018.10.014. Epub 2018 Nov 15.

PMID:
30449682
3.

Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence.

Mrazkova B, Dzijak R, Imrichova T, Kyjacova L, Barath P, Dzubak P, Holub D, Hajduch M, Nahacka Z, Andera L, Holicek P, Vasicova P, Sapega O, Bartek J, Hodny Z.

Aging (Albany NY). 2018 Mar 28;10(3):434-462. doi: 10.18632/aging.101404.

4.

TRAIL induces apoptosis but not necroptosis in colorectal and pancreatic cancer cells preferentially via the TRAIL-R2/DR5 receptor.

Nahacka Z, Svadlenka J, Peterka M, Ksandrova M, Benesova S, Neuzil J, Andera L.

Biochim Biophys Acta Mol Cell Res. 2018 Mar;1865(3):522-531. doi: 10.1016/j.bbamcr.2017.12.006. Epub 2017 Dec 24.

5.

Manipulating Wnt signaling at different subcellular levels affects the fate of neonatal neural stem/progenitor cells.

Kriska J, Honsa P, Dzamba D, Butenko O, Kolenicova D, Janeckova L, Nahacka Z, Andera L, Kozmik Z, Taketo MM, Korinek V, Anderova M.

Brain Res. 2016 Nov 15;1651:73-87. doi: 10.1016/j.brainres.2016.09.026. Epub 2016 Sep 19.

PMID:
27659965
6.

Human embryonic and induced pluripotent stem cells express TRAIL receptors and can be sensitized to TRAIL-induced apoptosis.

Vinarsky V, Krivanek J, Rankel L, Nahacka Z, Barta T, Jaros J, Andera L, Hampl A.

Stem Cells Dev. 2013 Nov 15;22(22):2964-74. doi: 10.1089/scd.2013.0057. Epub 2013 Aug 2.

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