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Is There a Role for Liver Transplantation in the Treatment of Patients With Metastatic Colorectal Cancer?

Rosen CB, Nagorney DM, Alberts SR.

Ann Surg. 2019 Dec 5. doi: 10.1097/SLA.0000000000003713. [Epub ahead of print] No abstract available.


Survival benefit of neoadjuvant therapy in patients with non-metastatic pancreatic ductal adenocarcinoma: A propensity matching and intention-to-treat analysis.

Sugimoto M, Takahashi N, Farnell MB, Smyrk TC, Truty MJ, Nagorney DM, Smoot RL, Chari ST, Carter RE, Kendrick ML.

J Surg Oncol. 2019 Nov;120(6):976-984. doi: 10.1002/jso.25681. Epub 2019 Aug 26.


Early-onset gastric cancer is a distinct disease with worrisome trends and oncogenic features.

Bergquist JR, Leiting JL, Habermann EB, Cleary SP, Kendrick ML, Smoot RL, Nagorney DM, Truty MJ, Grotz TE.

Surgery. 2019 Oct;166(4):547-555. doi: 10.1016/j.surg.2019.04.036. Epub 2019 Jul 20.


Bacterial Cholangitis in Autosomal Dominant Polycystic Kidney and Liver Disease.

Martin WP, Vaughan LE, Yoshida K, Takahashi N, Edwards ME, Metzger A, Senum SR, Masyuk TV, LaRusso NF, Griffin MD, El-Zoghby Z, Harris PC, Kremers WK, Nagorney DM, Kamath PS, Torres VE, Hogan MC.

Mayo Clin Proc Innov Qual Outcomes. 2019 May 27;3(2):149-159. doi: 10.1016/j.mayocpiqo.2019.03.004. eCollection 2019 Jun.


Novel Prognostic Factors in Resected Small Bowel Adenocarcinoma.

Huffman BM, Jin Z, Yadav S, Patel S, Nagorney DM, Truty MJ, McWilliams RR, Halfdanarson TR, Mahipal A.

Clin Colorectal Cancer. 2019 Sep;18(3):218-225. doi: 10.1016/j.clcc.2019.05.002. Epub 2019 May 15.


Factors Predicting Response, Perioperative Outcomes, and Survival Following Total Neoadjuvant Therapy for Borderline/Locally Advanced Pancreatic Cancer.

Truty MJ, Kendrick ML, Nagorney DM, Smoot RL, Cleary SP, Graham RP, Goenka AH, Hallemeier CL, Haddock MG, Harmsen WS, Mahipal A, McWilliams RR, Halfdanarson TR, Grothey AF.

Ann Surg. 2019 Apr 5. doi: 10.1097/SLA.0000000000003284. [Epub ahead of print]


Patient-Derived Xenografts Can Be Reliably Generated from Patient Clinical Biopsy Specimens.

Hernandez MC, Bergquist JR, Leiting JL, Ivanics T, Yang L, Smoot RL, Nagorney DM, Truty MJ.

J Gastrointest Surg. 2019 Apr;23(4):818-824. doi: 10.1007/s11605-019-04109-z. Epub 2019 Feb 12.


Radiation Therapy for Retroperitoneal Sarcomas: Influences of Histology, Grade, and Size.

Leiting JL, Bergquist JR, Hernandez MC, Merrell KW, Folpe AL, Robinson SI, Nagorney DM, Truty MJ, Grotz TE.

Sarcoma. 2018 Dec 5;2018:7972389. doi: 10.1155/2018/7972389. eCollection 2018.


Transversus abdominis plane blocks with liposomal bupivacaine after open major hepatectomy is associated with reduced early patient-reported pain scores and opioid administration.

Hernandez MC, Panchamia J, Finnesgard EJ, Leiting JL, Franssen B, Saleem H, Kendrick ML, Nagorney DM, Truty MJ, Smoot RL.

Surgery. 2018 Dec;164(6):1251-1258. doi: 10.1016/j.surg.2018.07.023. Epub 2018 Sep 7.


Partial hepatic resections for metastatic neuroendocrine tumors: perioperative outcomes.

Kinney MAO, Nagorney DM, Clark DF, O'Brien TD, Turner JD, Marienau ME, Schroeder DR, Martin DP.

J Clin Anesth. 2018 Dec;51:93-96. doi: 10.1016/j.jclinane.2018.08.005. Epub 2018 Aug 8.


Survival and Prognostic Factors in Patients With Solid Pseudopapillary Neoplasms of the Pancreas.

Huffman BM, Westin G, Alsidawi S, Alberts SR, Nagorney DM, Halfdanarson TR, Mahipal A.

Pancreas. 2018 Sep;47(8):1003-1007. doi: 10.1097/MPA.0000000000001112.


Early thrombotic events and preemptive systemic anticoagulation following splenectomy for myelofibrosis.

Mudireddy M, Gangat N, Lasho TL, Finke C, Hanson CA, Ketterling RP, Ashrani AA, Pardanani A, Nagorney DM, Tefferi A.

Am J Hematol. 2018 Sep;93(9):E235-E238. doi: 10.1002/ajh.25203. Epub 2018 Aug 31. No abstract available.


Indications and Perioperative Outcomes for Pancreatectomy with Arterial Resection.

Tee MC, Krajewski AC, Groeschl RT, Farnell MB, Nagorney DM, Kendrick ML, Cleary SP, Smoot RL, Croome KP, Truty MJ.

J Am Coll Surg. 2018 Aug;227(2):255-269. doi: 10.1016/j.jamcollsurg.2018.05.001. Epub 2018 May 9.


Outcome of Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Mayo Clinic Experience.

Jin Z, Sanhueza CT, Johnson B, Nagorney DM, Larson DW, Mara KC, Harmsen WC, Smyrk TC, Grothey A, Hubbard JM.

Oncologist. 2018 Sep;23(9):1083-1091. doi: 10.1634/theoncologist.2017-0289. Epub 2018 Apr 19.


Prognostic factors and benefits of adjuvant therapy after pancreatoduodenectomy for ampullary adenocarcinoma: Mayo Clinic experience.

Jin Z, Hartgers ML, Sanhueza CT, Shubert CR, Alberts SR, Truty MJ, Muppa P, Nagorney DM, Smyrk TC, Hassan M, Mahipal A.

Eur J Surg Oncol. 2018 May;44(5):677-683. doi: 10.1016/j.ejso.2018.02.008. Epub 2018 Feb 16.


Adjuvant systemic therapy after resection of node positive gallbladder cancer: Time for a well-designed trial? (Results of a US-national retrospective cohort study).

Bergquist JR, Shah HN, Habermann EB, Hernandez MC, Ivanics T, Kendrick ML, Smoot RL, Nagorney DM, Borad MJ, McWilliams RR, Truty MJ.

Int J Surg. 2018 Apr;52:171-179. doi: 10.1016/j.ijsu.2018.02.052. Epub 2018 Feb 26.


A Curative-Intent Trimodality Approach for Isolated Abdominal Nodal Metastases in Metastatic Colorectal Cancer: Update of a Single-Institutional Experience.

Johnson B, Jin Z, Haddock MG, Hallemeier CL, Martenson JA, Smoot RL, Larson DW, Dozois EJ, Nagorney DM, Grothey A.

Oncologist. 2018 Jun;23(6):679-685. doi: 10.1634/theoncologist.2017-0456. Epub 2018 Feb 14.


Decreased Skeletal Muscle Volume Is a Predictive Factor for Poorer Survival in Patients Undergoing Surgical Resection for Pancreatic Ductal Adenocarcinoma.

Sugimoto M, Farnell MB, Nagorney DM, Kendrick ML, Truty MJ, Smoot RL, Chari ST, Moynagh MR, Petersen GM, Carter RE, Takahashi N.

J Gastrointest Surg. 2018 May;22(5):831-839. doi: 10.1007/s11605-018-3695-z. Epub 2018 Feb 1.


Implementation of prospective, surgeon-driven, risk-based pathway for pancreatoduodenectomy results in improved clinical outcomes and first year cost savings of $1 million.

Shubert CR, Kendrick ML, Habermann EB, Glasgow AE, Borah BJ, Moriarty JP, Cleary SP, Smoot RL, Farnell MB, Nagorney DM, Truty MJ, Que FG.

Surgery. 2018 Mar;163(3):495-502. doi: 10.1016/j.surg.2017.10.022. Epub 2017 Dec 21.


Surgical Treatment of Hepatocellular Carcinoma.

Zamora-Valdes D, Taner T, Nagorney DM.

Cancer Control. 2017 Jul-Sep;24(3):1073274817729258. doi: 10.1177/1073274817729258. Review.


Impact of Metastasectomy in the Multimodality Approach for BRAF V600E Metastatic Colorectal Cancer: The Mayo Clinic Experience.

Johnson B, Jin Z, Truty MJ, Smoot RL, Nagorney DM, Kendrick ML, Kipp BR, Grothey A.

Oncologist. 2018 Jan;23(1):128-134. doi: 10.1634/theoncologist.2017-0230. Epub 2017 Sep 13.


Challenges in patient selection for liver resection or transplantation in patients with hepatocellular carcinoma beyond Milan criteria.

Zaydfudim VM, Chapman WC, Nagorney DM.

Hepatobiliary Surg Nutr. 2017 Aug;6(4):287-289. doi: 10.21037/hbsn.2017.07.04. No abstract available.


Risk factors and a prognostic model for postsplenectomy survival in myelofibrosis.

Tefferi A, Mudireddy M, Gangat N, Hanson CA, Ketterling RP, Pardanani A, Nagorney DM.

Am J Hematol. 2017 Nov;92(11):1187-1192. doi: 10.1002/ajh.24881. Epub 2017 Aug 24.


Type of Resection (Whipple vs. Distal) Does Not Affect the National Failure to Provide Post-resection Adjuvant Chemotherapy in Localized Pancreatic Cancer.

Bergquist JR, Ivanics T, Shubert CR, Habermann EB, Smoot RL, Kendrick ML, Nagorney DM, Farnell MB, Truty MJ.

Ann Surg Oncol. 2017 Jun;24(6):1731-1738. doi: 10.1245/s10434-016-5762-6. Epub 2017 Jan 9.


Surgical Treatment of Malignant Pheochromocytoma and Paraganglioma: Retrospective Case Series.

Strajina V, Dy BM, Farley DR, Richards ML, McKenzie TJ, Bible KC, Que FG, Nagorney DM, Young WF, Thompson GB.

Ann Surg Oncol. 2017 Jun;24(6):1546-1550. doi: 10.1245/s10434-016-5739-5. Epub 2017 Jan 5.


Mixed hepatocellular and cholangiocarcinoma: a rare tumor with a mix of parent phenotypic characteristics.

Bergquist JR, Groeschl RT, Ivanics T, Shubert CR, Habermann EB, Kendrick ML, Farnell MB, Nagorney DM, Truty MJ, Smoot RL.

HPB (Oxford). 2016 Nov;18(11):886-892. doi: 10.1016/j.hpb.2016.07.006. Epub 2016 Aug 18.


Overall survival is increased among stage III pancreatic adenocarcinoma patients receiving neoadjuvant chemotherapy compared to surgery first and adjuvant chemotherapy: An intention to treat analysis of the National Cancer Database.

Shubert CR, Bergquist JR, Groeschl RT, Habermann EB, Wilson PM, Truty MJ, Smoot RL, Kendrick ML, Nagorney DM, Farnell MB.

Surgery. 2016 Oct;160(4):1080-1096. doi: 10.1016/j.surg.2016.06.010. Epub 2016 Aug 10.


Implications of CA19-9 elevation for survival, staging, and treatment sequencing in intrahepatic cholangiocarcinoma: A national cohort analysis.

Bergquist JR, Ivanics T, Storlie CB, Groeschl RT, Tee MC, Habermann EB, Smoot RL, Kendrick ML, Farnell MB, Roberts LR, Gores GJ, Nagorney DM, Truty MJ.

J Surg Oncol. 2016 Sep;114(4):475-82. doi: 10.1002/jso.24381. Epub 2016 Jul 20.


Liver Resection and Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria.

Zaydfudim VM, Vachharajani N, Klintmalm GB, Jarnagin WR, Hemming AW, Doyle MB, Cavaness KM, Chapman WC, Nagorney DM.

Ann Surg. 2016 Oct;264(4):650-8. doi: 10.1097/SLA.0000000000001866.


How matching may impact interpretation: Comments on "A matched-cohort analysis of 192 pancreatic anaplastic carcinomas and 960 pancreatic adenocarcinomas: A 13-year North American experience using the National Cancer Data Base (NCDB)".

Bergquist JR, Thiels CA, Storlie CB, Nagorney DM, Truty MJ.

Surgery. 2016 Dec;160(6):1714-1715. doi: 10.1016/j.surg.2016.05.011. Epub 2016 Jun 28. No abstract available.


Hepatic Resection for Metastatic Neuroendocrine Cancer in Patients with Bone Metastases.

Croome KP, Burns JM, G Que F, Nagorney DM.

Ann Surg Oncol. 2016 Oct;23(11):3693-3698. doi: 10.1245/s10434-016-5274-4. Epub 2016 May 17.


Portal vein reconstruction during surgery for cholangiocarcinoma.

Groeschl RT, Nagorney DM.

Curr Opin Gastroenterol. 2016 May;32(3):216-24. doi: 10.1097/MOG.0000000000000259. Review.


Carbohydrate Antigen 19-9 Elevation in Anatomically Resectable, Early Stage Pancreatic Cancer Is Independently Associated with Decreased Overall Survival and an Indication for Neoadjuvant Therapy: A National Cancer Database Study.

Bergquist JR, Puig CA, Shubert CR, Groeschl RT, Habermann EB, Kendrick ML, Nagorney DM, Smoot RL, Farnell MB, Truty MJ.

J Am Coll Surg. 2016 Jul;223(1):52-65. doi: 10.1016/j.jamcollsurg.2016.02.009. Epub 2016 Feb 23.


Outcomes and Durability of Hepatic Reduction after Combined Partial Hepatectomy and Cyst Fenestration for Massive Polycystic Liver Disease.

Chebib FT, Harmon A, Irazabal Mira MV, Jung YS, Edwards ME, Hogan MC, Kamath PS, Torres VE, Nagorney DM.

J Am Coll Surg. 2016 Jul;223(1):118-126.e1. doi: 10.1016/j.jamcollsurg.2015.12.051. Epub 2016 Jan 14.


Safety of an Enhanced Recovery Pathway for Patients Undergoing Open Hepatic Resection.

Clark CJ, Ali SM, Zaydfudim V, Jacob AK, Nagorney DM.

PLoS One. 2016 Mar 7;11(3):e0150782. doi: 10.1371/journal.pone.0150782. eCollection 2016.


Outcomes of Pancreaticoduodenectomy for Pancreatic Neuroendocrine Tumors: Are Combined Procedures Justified?

Thiels CA, Bergquist JR, Laan DV, Croome KP, Smoot RL, Nagorney DM, Thompson GB, Kendrick ML, Farnell MB, Truty MJ.

J Gastrointest Surg. 2016 May;20(5):891-8. doi: 10.1007/s11605-016-3102-6. Epub 2016 Feb 29.


Metabolic Syndrome is Associated with Increased Postoperative Morbidity and Hospital Resource Utilization in Patients Undergoing Elective Pancreatectomy.

Tee MC, Ubl DS, Habermann EB, Nagorney DM, Kendrick ML, Sarr MG, Truty MJ, Que FG, Reid-Lombardo K, Smoot RL, Farnell MB.

J Gastrointest Surg. 2016 Jan;20(1):189-98; discussion 198. doi: 10.1007/s11605-015-3007-9. Epub 2015 Nov 9.


Pancreatoduodenectomy for Chronic Pancreatitis-Results of a Pain Relief and Quality of Life Survey 15 Years Following Operation.

Croome KP, Tee M, Nagorney DM, Truty MJ, Reid-Lombardo KM, Que FG, Kendrick ML, Farnell MB.

J Gastrointest Surg. 2015 Dec;19(12):2146-53. doi: 10.1007/s11605-015-2928-7. Epub 2015 Sep 2.


Clinical Risk Score to Predict Pancreatic Fistula after Pancreatoduodenectomy: Independent External Validation for Open and Laparoscopic Approaches.

Shubert CR, Wagie AE, Farnell MB, Nagorney DM, Que FG, Reid Lombardo KM, Truty MJ, Smoot RL, Kendrick ML.

J Am Coll Surg. 2015 Sep;221(3):689-98. doi: 10.1016/j.jamcollsurg.2015.05.011. Epub 2015 May 21.


Laparoscopic pancreatoduodenectomy does not completely mitigate increased perioperative risks in elderly patients.

Tee MC, Croome KP, Shubert CR, Farnell MB, Truty MJ, Que FG, Reid-Lombardo KM, Smoot RL, Nagorney DM, Kendrick ML.

HPB (Oxford). 2015 Oct;17(10):909-18. doi: 10.1111/hpb.12456. Epub 2015 Aug 20.


A NSQIP Review of Major Morbidity and Mortality of Synchronous Liver Resection for Colorectal Metastasis Stratified by Extent of Liver Resection and Type of Colorectal Resection.

Shubert CR, Habermann EB, Bergquist JR, Thiels CA, Thomsen KM, Kremers WK, Kendrick ML, Cima RR, Nagorney DM.

J Gastrointest Surg. 2015 Nov;19(11):1982-94. doi: 10.1007/s11605-015-2895-z. Epub 2015 Aug 4.


Characterization of a porcine model for associating liver partition and portal vein ligation for a staged hepatectomy.

Croome KP, Mao SA, Glorioso JM, Krishna M, Nyberg SL, Nagorney DM.

HPB (Oxford). 2015 Dec;17(12):1130-6. doi: 10.1111/hpb.12465. Epub 2015 Aug 2.


Preoperative anemia is associated with increased use of hospital resources in patients undergoing elective hepatectomy.

Tee MC, Shubert CR, Ubl DS, Habermann EB, Nagorney DM, Que FG.

Surgery. 2015 Oct;158(4):1027-36; discussion 1036-8. doi: 10.1016/j.surg.2015.06.004. Epub 2015 Jul 7.


The American Society of Surgical Oncology travel grant.

Nagorney DM.

Eur J Surg Oncol. 2015 Apr;41(4):441. No abstract available.


Is Liver Transplantation Appropriate for Patients with Potentially Resectable De Novo Hilar Cholangiocarcinoma?

Croome KP, Rosen CB, Heimbach JK, Nagorney DM.

J Am Coll Surg. 2015 Jul;221(1):130-9. doi: 10.1016/j.jamcollsurg.2015.01.064. Epub 2015 Mar 11.


Operative interventions for extrahepatic portomesenteric venous aneurysms and long-term outcomes.

Fleming MD, Lall P, Nagorney DM, Gloviczki P, Kalra M, Duncan A, Oderich G, Toomey B, Bower TC.

Ann Vasc Surg. 2015;29(4):654-60. doi: 10.1016/j.avsg.2015.01.029. Epub 2015 Mar 11.


Is the liver kinetic growth rate in ALPPS unprecedented when compared with PVE and living donor liver transplant? A multicentre analysis.

Croome KP, Hernandez-Alejandro R, Parker M, Heimbach J, Rosen C, Nagorney DM.

HPB (Oxford). 2015 Jun;17(6):477-84. doi: 10.1111/hpb.12386. Epub 2015 Feb 28.


Unique genomic profile of fibrolamellar hepatocellular carcinoma.

Cornella H, Alsinet C, Sayols S, Zhang Z, Hao K, Cabellos L, Hoshida Y, Villanueva A, Thung S, Ward SC, Rodriguez-Carunchio L, Vila-Casadesús M, Imbeaud S, Lachenmayer A, Quaglia A, Nagorney DM, Minguez B, Carrilho F, Roberts LR, Waxman S, Mazzaferro V, Schwartz M, Esteller M, Heaton ND, Zucman-Rossi J, Llovet JM.

Gastroenterology. 2015 Apr;148(4):806-18.e10. doi: 10.1053/j.gastro.2014.12.028. Epub 2014 Dec 31.


Necrotic ulcerations after splenectomy.

Tolkachjov SN, Wetter DA, Fahy AS, Nagorney DM, Camilleri MJ.

Int J Dermatol. 2015 Mar;54(3):251-4. doi: 10.1111/ijd.12697. Epub 2014 Dec 19. No abstract available.


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