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Items: 1 to 50 of 279

1.

Temporary hypertension and white coat hypertension in the first trimester as risk factors for preeclampsia.

Ohkuchi A, Hirashima C, Arai R, Takahashi K, Suzuki H, Ogoyama M, Nagayama S, Takahashi H, Baba Y, Usui R, Shirasuna K, Matsubara S.

Hypertens Res. 2019 Aug 9. doi: 10.1038/s41440-019-0307-6. [Epub ahead of print]

PMID:
31399709
2.

Preeclamptic patient-derived circulating cell-free DNA activates the production of inflammatory cytokines via toll-like receptor 9 signalling in the human placenta.

Ozeki A, Tani K, Takahashi H, Suzuki H, Nagayama S, Hirashima C, Iwata H, Kuwayama T, Ohkuchi A, Shirasuna K.

J Hypertens. 2019 Dec;37(12):2452-2460. doi: 10.1097/HJH.0000000000002208.

PMID:
31385869
3.

Needlescopic surgery for very low rectal cancer with no abdominal skin incision.

Fukuoka H, Fukunaga Y, Minami H, Miyanari S, Suzuki S, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Ueno M.

Asian J Endosc Surg. 2019 Jul 7. doi: 10.1111/ases.12730. [Epub ahead of print]

PMID:
31282070
4.

The short-term outcomes of laparoscopic-endoscopic cooperative surgery for colorectal tumors (LECS-CR) in cases involving endoscopically unresectable colorectal tumors.

Suzuki S, Fukunaga Y, Tamegai Y, Akiyoshi T, Konishi T, Nagayama S, Saito S, Ueno M.

Surg Today. 2019 Jun 27. doi: 10.1007/s00595-019-01840-7. [Epub ahead of print]

PMID:
31250113
5.

Conservative management of retained products of conception in the normal placental position: A retrospective observational study.

Takahashi H, Ohhashi M, Baba Y, Nagayama S, Ogoyama M, Horie K, Suzuki H, Usui R, Ohkuchi A, Matsubara S.

Eur J Obstet Gynecol Reprod Biol. 2019 Sep;240:87-92. doi: 10.1016/j.ejogrb.2019.06.016. Epub 2019 Jun 19.

PMID:
31238204
6.

Protons Differentially Activate TDAG8 Homologs from Various Species.

Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H.

Zoolog Sci. 2019 Apr 1;36(2):105-111. doi: 10.2108/zs180128.

PMID:
31120644
7.

Feasibility of needlescopic surgery for colorectal cancer: safety and learning curve for Japanese Endoscopic Surgical Skill Qualification System-unqualified young surgeons.

Miki H, Fukunaga Y, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Ueno M.

Surg Endosc. 2019 May 13. doi: 10.1007/s00464-019-06824-9. [Epub ahead of print]

PMID:
31087171
8.

TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients.

Matsuda T, Miyauchi E, Hsu YW, Nagayama S, Kiyotani K, Zewde M, Park JH, Kato T, Harada M, Matsui S, Ueno M, Fukuda K, Suzuki N, Hazama S, Nagano H, Takeuchi H, Vigneswaran WT, Kitagawa Y, Nakamura Y.

Oncoimmunology. 2019 Mar 22;8(6):e1588085. doi: 10.1080/2162402X.2019.1588085. eCollection 2019.

PMID:
31069156
9.

Laparoscopic-endoscopic cooperative surgery for ileal lipoma: A case report.

Nakanishi R, Fukunaga Y, Nagasaki T, Emoto S, Hirayama K, Yoshioka S, Kitagawa Y, Honma S, Nagaoka T, Matsui S, Tominaga T, Minami H, Miyanari S, Yamaguchi T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Saito S, Ueno M.

Asian J Endosc Surg. 2019 Apr 11. doi: 10.1111/ases.12706. [Epub ahead of print]

PMID:
30977295
10.

Phase II Trial of Neoadjuvant Chemotherapy, Chemoradiotherapy, and Laparoscopic Surgery with Selective Lateral Node Dissection for Poor-Risk Low Rectal Cancer.

Konishi T, Shinozaki E, Murofushi K, Taguchi S, Fukunaga Y, Nagayama S, Fujimoto Y, Akiyoshi T, Nagasaki T, Suenaga M, Chino A, Kawachi H, Yamamoto N, Ishikawa Y, Oguchi M, Ishizuka N, Ueno M, Yamaguchi K.

Ann Surg Oncol. 2019 Aug;26(8):2507-2513. doi: 10.1245/s10434-019-07342-7. Epub 2019 Apr 8.

PMID:
30963400
11.

Feasibility of neoadjuvant therapy for elderly patients with locally advanced rectal cancer.

Tominaga T, Nagasaki T, Akiyoshi T, Fukunaga Y, Fujimoto Y, Yamaguchi T, Konishi T, Nagayama S, Ueno M.

Surg Today. 2019 Aug;49(8):694-703. doi: 10.1007/s00595-019-01801-0. Epub 2019 Apr 1.

PMID:
30937632
12.

Narrowly Confined and Glomerulus-Specific Onset Latencies of Odor-Evoked Calcium Transients in the Juxtaglomerular Cells of the Mouse Main Olfactory Bulb.

Homma R, Lv X, Sato T, Imamura F, Zeng S, Nagayama S.

eNeuro. 2019 Feb 28;6(1). pii: ENEURO.0387-18.2019. doi: 10.1523/ENEURO.0387-18.2019. eCollection 2019 Jan-Feb.

13.

Corrigendum to "Increased serum levels of sFlt-1/PlGF ratio in preeclamptic women with onset at <32 weeks compared with ≥32 weeks" [Pregnancy Hypertens. 12 (2018) 96-103].

Suzuki H, Hirashima C, Nagayama S, Takahashi K, Yamamoto T, Matsubara S, Ohkuchi A.

Pregnancy Hypertens. 2019 Jan;15:181. doi: 10.1016/j.preghy.2019.01.006. Epub 2019 Feb 1. No abstract available.

PMID:
30825919
14.

Difficulty of predicting lymph node metastasis on CT in patients with rectal neuroendocrine tumors.

Ushigome H, Fukunaga Y, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Ueno M.

PLoS One. 2019 Feb 11;14(2):e0211675. doi: 10.1371/journal.pone.0211675. eCollection 2019.

15.

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens.

Kohsaka S, Tatsuno K, Ueno T, Nagano M, Shinozaki-Ushiku A, Ushiku T, Takai D, Ikegami M, Kobayashi H, Kage H, Ando M, Hata K, Ueda H, Yamamoto S, Kojima S, Oseto K, Akaike K, Suehara Y, Hayashi T, Saito T, Takahashi F, Takahashi K, Takamochi K, Suzuki K, Nagayama S, Oda Y, Mimori K, Ishihara S, Yatomi Y, Nagase T, Nakajima J, Tanaka S, Fukayama M, Oda K, Nangaku M, Miyazono K, Miyagawa K, Aburatani H, Mano H.

Cancer Sci. 2019 Apr;110(4):1464-1479. doi: 10.1111/cas.13968. Epub 2019 Mar 5.

16.

IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer.

Sakahara M, Okamoto T, Oyanagi J, Takano H, Natsume Y, Yamanaka H, Kusama D, Fusejima M, Tanaka N, Mori S, Kawachi H, Ueno M, Sakai Y, Noda T, Nagayama S, Yao R.

Cancer Sci. 2019 Apr;110(4):1293-1305. doi: 10.1111/cas.13964. Epub 2019 Mar 22.

17.

The Short- and Long-Term Feasibility of Laparoscopic Surgery in Colon Cancer Patients with Bulky Tumors.

Nagasaki T, Akiyoshi T, Fukunaga Y, Tominaga T, Yamaguchi T, Konishi T, Fujimoto Y, Nagayama S, Ueno M.

J Gastrointest Surg. 2019 Sep;23(9):1893-1899. doi: 10.1007/s11605-019-04114-2. Epub 2019 Jan 31.

PMID:
30706379
18.

Serum soluble LIGHT in the early third trimester as a novel biomarker for predicting late-onset preeclampsia.

Hirashima C, Ohmaru-Nakanishi T, Nagayama S, Takahashi K, Suzuki H, Takahashi H, Usui R, Shirasuna K, Matsubara S, Ohkuchi A.

Pregnancy Hypertens. 2018 Oct;14:174-176. doi: 10.1016/j.preghy.2018.10.004. Epub 2018 Oct 13.

PMID:
30527108
19.

Evaluation of repeated progression of native coronary artery stenosis by optical frequency domain imaging in a patient with essential thrombocytosis.

Tamaru H, Fujii K, Otsuji S, Takiuchi S, Hasegawa K, Ishibuchi K, Ishii R, Yamamoto W, Nakabayashi S, Kakishita M, Ibuki M, Nagayama S, Higashino Y.

J Cardiol Cases. 2018 May 30;18(2):74-77. doi: 10.1016/j.jccase.2018.04.009. eCollection 2018 Aug.

20.

Markedly higher sFlt-1/PlGF ratio in a woman with acute fatty liver of pregnancy compared with HELLP syndrome.

Suzuki H, Nagayama S, Hirashima C, Takahashi K, Takahashi H, Ogoyama M, Nagayama M, Shirasuna K, Matsubara S, Ohkuchi A.

J Obstet Gynaecol Res. 2019 Jan;45(1):96-103. doi: 10.1111/jog.13786. Epub 2018 Aug 23.

PMID:
30141235
21.

Improved phosphoproteomic analysis for phosphosignaling and active-kinome profiling in Matrigel-embedded spheroids and patient-derived organoids.

Abe Y, Tada A, Isoyama J, Nagayama S, Yao R, Adachi J, Tomonaga T.

Sci Rep. 2018 Jul 30;8(1):11401. doi: 10.1038/s41598-018-29837-1.

22.

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer.

Saito T, Niida A, Uchi R, Hirata H, Komatsu H, Sakimura S, Hayashi S, Nambara S, Kuroda Y, Ito S, Eguchi H, Masuda T, Sugimachi K, Tobo T, Nishida H, Daa T, Chiba K, Shiraishi Y, Yoshizato T, Kodama M, Okimoto T, Mizukami K, Ogawa R, Okamoto K, Shuto M, Fukuda K, Matsui Y, Shimamura T, Hasegawa T, Doki Y, Nagayama S, Yamada K, Kato M, Shibata T, Mori M, Aburatani H, Murakami K, Suzuki Y, Ogawa S, Miyano S, Mimori K.

Nat Commun. 2018 Jul 23;9(1):2884. doi: 10.1038/s41467-018-05226-0.

23.

α-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.

Li HK, Sugyo A, Tsuji AB, Morokoshi Y, Minegishi K, Nagatsu K, Kanda H, Harada Y, Nagayama S, Katagiri T, Nakamura Y, Higashi T, Hasegawa S.

Cancer Sci. 2018 Jul;109(7):2302-2309. doi: 10.1111/cas.13636. Epub 2018 Jun 27.

24.

Predicting the ecological impacts of large-dam removals on a river network based on habitat-network structure and flow regimes.

Ishiyama N, Ryo M, Kataoka T, Nagayama S, Sueyoshi M, Terui A, Mori T, Akasaka T, Nakamura F.

Conserv Biol. 2018 Dec;32(6):1403-1413. doi: 10.1111/cobi.13137. Epub 2018 Aug 24.

PMID:
29785835
25.

Rheumatoid meningitis developed in patient with stable rheumatoid arthritis and myasthenia gravis-detailed analysis of intracranial inflammation using flow cytometry.

Oono M, Fujita Y, Uchida N, Kawai U, Fujita-Nakata M, Nakanishi M, Sanada M, Nagayama S, Matsui M.

J Neuroinflammation. 2018 May 18;15(1):151. doi: 10.1186/s12974-018-1196-3.

26.

Increased serum levels of sFlt-1/PlGF ratio in preeclamptic women with onset at <32 weeks compared with ≥32 weeks.

Suzuki H, Hirashima C, Nagayama S, Takahashi K, Yamamoto T, Matsubara S, Ohkuchi A.

Pregnancy Hypertens. 2018 Apr;12:96-103. doi: 10.1016/j.preghy.2018.03.008. Epub 2018 Mar 19. Erratum in: Pregnancy Hypertens. 2019 Jan;15:181.

PMID:
29674208
27.

Laparoscopic right hemicolectomy for a colon cancer patient with an ileal conduit.

Suzuki S, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Fukunaga Y, Fukuoka H, Ushigome H, Murahashi S, Miyanari S, Minami H, Ueno M.

Asian J Endosc Surg. 2019 Jan;12(1):114-117. doi: 10.1111/ases.12486. Epub 2018 Apr 6.

PMID:
29624907
28.

A Feasibility Study of Capecitabine and Oxaliplatin for Patients with Stage II/III Colon Cancer -ACTOR Study.

Suenaga M, Akiyoshi T, Shinozaki E, Fujimoto Y, Matsusaka S, Konishi T, Nagayama S, Fukunaga Y, Kawakami K, Yokokawa T, Sugisaki T, Ueno M, Yamaguchi T.

Anticancer Res. 2018 Mar;38(3):1741-1747.

PMID:
29491111
29.

GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y, Nakamura Y, Kubo M, Matsuda K.

Carcinogenesis. 2018 May 3;39(5):652-660. doi: 10.1093/carcin/bgy026.

PMID:
29471430
30.

[A Case of Lymph Node Metastasis of Rectal Laterally Spreading Tumor with Mucosal Cancer after Endoscopic Submucosal Dissection].

Ushigome H, Fujimoto Y, Suzuki S, Minami H, Miyanari S, Murahashi S, Fukuoka H, Nagasaki T, Akiyoshi T, Konishi T, Nagayama S, Fukunaga Y, Ueno M, Chino A, Igarashi M.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1562-1564. Japanese.

PMID:
29394702
31.

[A Case with Metastatic Huge Ovarian Tumor from Transverse Colon Cancer, Who Underwent Systemic Chemotherapy after Bilateral Oophorectomy and Right Hemi Colectomy].

Miyanari S, Nagasaki T, Minami H, Fukuoka H, Murahashi S, Suzuki S, Ushigome H, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1526-1528. Japanese.

PMID:
29394690
32.

[Safety of Laparoscopic Surgery after Preoperative Short Course Radiotherapy for Lower Rectal Cancer].

Minami H, Konishi T, Fukuoka H, Miyanari S, Murahashi S, Fukudome I, Suzuki S, Ushigome H, Nagasaki T, Akiyoshi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1506-1508. Japanese.

PMID:
29394683
33.

Understanding intratumor heterogeneity by combining genome analysis and mathematical modeling.

Niida A, Nagayama S, Miyano S, Mimori K.

Cancer Sci. 2018 Apr;109(4):884-892. doi: 10.1111/cas.13510. Epub 2018 Feb 28. Review.

34.

Laparoscopic repair of bowel herniation into the space between the obturator nerve and the umbilical artery after pelvic lymphadenectomy for cervical cancer.

Minami H, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Fukunaga Y, Fukuoka H, Ueno M.

Asian J Endosc Surg. 2018 Nov;11(4):409-412. doi: 10.1111/ases.12458. Epub 2018 Jan 4.

PMID:
29314767
35.

Unique Configurations of Compression and Truncation of Neuronal Activity Underlie l-DOPA-Induced Selection of Motor Patterns in Aplysia.

Neveu CL, Costa RM, Homma R, Nagayama S, Baxter DA, Byrne JH.

eNeuro. 2017 Oct 24;4(5). pii: ENEURO.0206-17.2017. doi: 10.1523/ENEURO.0206-17.2017. eCollection 2017 Sep-Oct.

36.

Galectin-1 as a novel risk factor for both gestational hypertension and preeclampsia, specifially its expression at a low level in the second trimester and a high level after onset.

Hirashima C, Ohkuchi A, Nagayama S, Suzuki H, Takahashi K, Ogoyama M, Takahashi H, Shirasuna K, Matsubara S.

Hypertens Res. 2018 Jan;41(1):45-52. doi: 10.1038/hr.2017.85. Epub 2017 Oct 5.

PMID:
28978981
37.

Pretreatment Serum Carbohydrate Antigen 19-9 Concentration Is a Predictor of Survival of Patients Who Have Undergone Curative Resection of Stage IV Rectal Cancer.

Miki H, Akiyoshi T, Ogura A, Nagasaki T, Konishi T, Fujimoto Y, Nagayama S, Noma H, Saiura A, Fukunaga Y, Ueno M.

Dig Surg. 2018;35(5):389-396. doi: 10.1159/000480247. Epub 2017 Sep 1.

PMID:
28858867
38.

Laparoscopic dissection of Merkel cell carcinoma recurrence at the pelvic lymph node.

Watanabe G, Fukunaga Y, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Ueno M.

Asian J Endosc Surg. 2017 Nov;10(4):427-429. doi: 10.1111/ases.12389. Epub 2017 Jul 6.

PMID:
28682014
39.

Accuracy of J-CTO Score Derived From Computed Tomography Versus Angiography to Predict Successful Percutaneous Coronary Intervention.

Fujino A, Otsuji S, Hasegawa K, Arita T, Takiuchi S, Fujii K, Yabuki M, Ibuki M, Nagayama S, Ishibuchi K, Kashiyama T, Ishii R, Tamaru H, Yamamoto W, Hara M, Higashino Y.

JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 1):209-217. doi: 10.1016/j.jcmg.2017.01.028. Epub 2017 Jun 14.

40.

Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis.

Zhou H, Mori S, Ishizaki T, Takahashi A, Matsuda K, Koretsune Y, Minami S, Higashiyama M, Imai S, Yoshimori K, Doita M, Yamada A, Nagayama S, Kaneko K, Asai S, Shiono M, Kubo M, Ito H.

Bone Rep. 2016 Jul 12;5:168-172. doi: 10.1016/j.bonr.2016.07.001. eCollection 2016 Dec.

41.

Change in clinical outcomes during the transition of adjuvant chemotherapy for stage III colorectal cancer.

Osumi H, Shinozaki E, Suenaga M, Wakatsuki T, Nakayama I, Matsushima T, Ogura M, Ichimura T, Takahari D, Chin K, Nagasaki T, Konishi T, Akiyoshi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M, Yamaguchi K.

PLoS One. 2017 May 31;12(5):e0176745. doi: 10.1371/journal.pone.0176745. eCollection 2017.

42.

Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.

Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K.

PLoS Genet. 2017 May 19;13(5):e1006798. doi: 10.1371/journal.pgen.1006798. eCollection 2017 May.

43.

Hysterectomy for cesarean scar pregnancy: no or minimal bladder separation technique.

Matsubara S, Nagayama S, Narumi R, Usui R, Suzuki T.

Acta Obstet Gynecol Scand. 2017 Jul;96(7):898-899. doi: 10.1111/aogs.13129. Epub 2017 Mar 29. No abstract available.

PMID:
28295157
44.

Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4.

Negishi J, Omori Y, Shindo M, Takanashi H, Musha S, Nagayama S, Hirayama J, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Mochimaru Y, Tomura H.

J Recept Signal Transduct Res. 2017 Aug;37(4):401-408. doi: 10.1080/10799893.2017.1298130. Epub 2017 Mar 7.

PMID:
28270026
45.

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.

Tanaka N, Mashima T, Mizutani A, Sato A, Aoyama A, Gong B, Yoshida H, Muramatsu Y, Nakata K, Matsuura M, Katayama R, Nagayama S, Fujita N, Sugimoto Y, Seimiya H.

Mol Cancer Ther. 2017 Apr;16(4):752-762. doi: 10.1158/1535-7163.MCT-16-0578. Epub 2017 Feb 8.

46.

Short- and Long-term Outcomes of Laparoscopic Total Mesenteric Excision for Neuroendocrine Tumors of the Rectum.

Takatsu Y, Fukunaga Y, Nagasaki T, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Ueno M.

Dis Colon Rectum. 2017 Mar;60(3):284-289. doi: 10.1097/DCR.0000000000000745.

PMID:
28177990
47.

Deep imaging in scattering media with selective plane illumination microscopy.

Pediredla AK, Zhang S, Avants B, Ye F, Nagayama S, Chen Z, Kemere C, Robinson JT, Veeraraghavan A.

J Biomed Opt. 2016 Dec 1;21(12):126009. doi: 10.1117/1.JBO.21.12.126009.

48.

Simultaneous occurrence of spontaneous coronary artery dissections of the left anterior descending and right coronary arteries in acute myocardial infarction.

Yamamoto W, Fujii K, Otsuji S, Takiuchi S, Hasegawa K, Ishibuchi K, Kashiyama T, Tamaru H, Ishii R, Yabuki M, Ibuki M, Nagayama S, Higashino Y.

J Cardiol Cases. 2016 Dec 7;15(3):84-87. doi: 10.1016/j.jccase.2016.10.012. eCollection 2017 Mar.

49.

Randomized clinical trial of oral and intravenous versus intravenous antibiotic prophylaxis for laparoscopic colorectal resection.

Ikeda A, Konishi T, Ueno M, Fukunaga Y, Nagayama S, Fujimoto Y, Akiyoshi T, Yamaguchi T.

Br J Surg. 2016 Nov;103(12):1608-1615. doi: 10.1002/bjs.10281. Epub 2016 Aug 23.

PMID:
27550722
50.

Patient-centered outcomes to decide treatment strategy for patients with low rectal cancer.

Honda M, Akiyoshi T, Noma H, Ogura A, Nagasaki T, Konishi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M.

J Surg Oncol. 2016 Oct;114(5):630-636. doi: 10.1002/jso.24376. Epub 2016 Oct 20.

PMID:
27761895

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