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Items: 1 to 50 of 58

1.
2.

Chronic intracerebroventricular administration of relaxin-3 increases body weight in rats.

Hida T, Takahashi E, Shikata K, Hirohashi T, Sawai T, Seiki T, Tanaka H, Kawai T, Ito O, Arai T, Yokoi A, Hirakawa T, Ogura H, Nagasu T, Miyamoto N, Kuromitsu J.

J Recept Signal Transduct Res. 2006;26(3):147-58.

PMID:
16777712
4.

Altered nociceptive response in ADAM11-deficient mice.

Takahashi E, Sagane K, Nagasu T, Kuromitsu J.

Brain Res. 2006 Jun 30;1097(1):39-42. Epub 2006 May 26.

PMID:
16729981
5.

Deficits in spatial learning and motor coordination in ADAM11-deficient mice.

Takahashi E, Sagane K, Oki T, Yamazaki K, Nagasu T, Kuromitsu J.

BMC Neurosci. 2006 Feb 26;7:19.

7.

Specificity of immobilized metal affinity-based IMAC/C18 tip enrichment of phosphopeptides for protein phosphorylation analysis.

Kokubu M, Ishihama Y, Sato T, Nagasu T, Oda Y.

Anal Chem. 2005 Aug 15;77(16):5144-54.

PMID:
16097752
8.

Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein.

Ishihama Y, Oda Y, Tabata T, Sato T, Nagasu T, Rappsilber J, Mann M.

Mol Cell Proteomics. 2005 Sep;4(9):1265-72. Epub 2005 Jun 14.

10.

Ataxia and peripheral nerve hypomyelination in ADAM22-deficient mice.

Sagane K, Hayakawa K, Kai J, Hirohashi T, Takahashi E, Miyamoto N, Ino M, Oki T, Yamazaki K, Nagasu T.

BMC Neurosci. 2005 May 6;6:33.

11.

Increased glucose tolerance in N-type Ca2+ channel alpha(1B)-subunit gene-deficient mice.

Takahashi E, Ito M, Miyamoto N, Nagasu T, Ino M, Tanaka I.

Int J Mol Med. 2005 Jun;15(6):937-44.

PMID:
15870896
12.

Quantitative mouse brain proteomics using culture-derived isotope tags as internal standards.

Ishihama Y, Sato T, Tabata T, Miyamoto N, Sagane K, Nagasu T, Oda Y.

Nat Biotechnol. 2005 May;23(5):617-21. Epub 2005 Apr 17.

PMID:
15834404
15.

Efficient in-gel digestion procedure using 5-cyclohexyl-1-pentyl-beta-D-maltoside as an additive for gel-based membrane proteomics.

Katayama H, Tabata T, Ishihama Y, Sato T, Oda Y, Nagasu T.

Rapid Commun Mass Spectrom. 2004;18(20):2388-94.

PMID:
15386632
16.

Synthesis and evaluation of novel pyrimido-acridone, -phenoxadine, and -carbazole as topoisomerase II inhibitors.

Kamata J, Okada T, Kotake Y, Niijima J, Nakamura K, Uenaka T, Yamaguchi A, Tsukahara K, Nagasu T, Koyanagi N, Kitoh K, Yoshimatsu K, Yoshino H, Sugumi H.

Chem Pharm Bull (Tokyo). 2004 Sep;52(9):1071-81.

17.

Expression of a human SOCS protein, HSOCP-1, in peripheral blood eosinophils from patients with atopic dermatitis.

Ogawa K, Itoh M, Miyagawa M, Nagasu T, Sugita Y, Katsunuma T, Akasawa A, Matsumoto K, Tsujimoto G, Saito H, Hashida R.

Int Arch Allergy Immunol. 2004 Jun;134 Suppl 1:2-6.

PMID:
15166476
18.

Increased expression of P/Q-type Ca2+ channel alpha1A subunit mRNA in cerebellum of N-type Ca2+ channel alpha1B subunit gene-deficient mice.

Takahashi E, Ino M, Miyamoto N, Nagasu T.

Brain Res Mol Brain Res. 2004 Apr 29;124(1):79-87.

PMID:
15093688
19.
20.

Reduced neuropeptide Y mRNA levels in the frontal cortex of people with schizophrenia and bipolar disorder.

Kuromitsu J, Yokoi A, Kawai T, Nagasu T, Aizawa T, Haga S, Ikeda K.

Brain Res Gene Expr Patterns. 2001 Aug;1(1):17-21.

PMID:
15018814
21.

Analysis of gene expression in peripheral blood eosinophils from patients with atopic dermatitis by differential display.

Hashida R, Ogawa K, Miyagawa M, Sugita Y, Takahashi E, Nagasu T, Katsunuma T, Akasawa A, Tsujimoto G, Matsumoto K, Saito H.

Int Arch Allergy Immunol. 2003 Jun;131 Suppl 1:26-33.

PMID:
12771546
22.

Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly.

Tsukahara K, Hata K, Nakamoto K, Sagane K, Watanabe NA, Kuromitsu J, Kai J, Tsuchiya M, Ohba F, Jigami Y, Yoshimatsu K, Nagasu T.

Mol Microbiol. 2003 May;48(4):1029-42.

23.

Quantitative chemical proteomics for identifying candidate drug targets.

Oda Y, Owa T, Sato T, Boucher B, Daniels S, Yamanaka H, Shinohara Y, Yokoi A, Kuromitsu J, Nagasu T.

Anal Chem. 2003 May 1;75(9):2159-65.

PMID:
12720356
24.

Optimization of in-gel protein digestion system in combination with thin-gel separation and negative staining in 96-well plate format.

Katayama H, Satoh K, Takeuchi M, Deguchi-Tawarada M, Oda Y, Nagasu T.

Rapid Commun Mass Spectrom. 2003;17(10):1071-8.

PMID:
12720288
25.

A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.

Nakamura K, Uenaka T, Nagasu T, Sugumi H, Yamaguchi A, Kotake Y, Okada T, Kamata J, Niijima J, Taniguchi T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.

Cancer Sci. 2003 Jan;94(1):119-24.

26.

Identification of highly expressed genes in peripheral blood T cells from patients with atopic dermatitis.

Matsumoto Y, Oshida T, Obayashi I, Imai Y, Matsui K, Yoshida NL, Nagata N, Ogawa K, Obayashi M, Kashiwabara T, Gunji S, Nagasu T, Sugita Y, Tanaka T, Tsujimoto G, Katsunuma T, Akasawa A, Saito H.

Int Arch Allergy Immunol. 2002 Dec;129(4):327-40.

PMID:
12483038
27.

Profiling novel sulfonamide antitumor agents with cell-based phenotypic screens and array-based gene expression analysis.

Yokoi A, Kuromitsu J, Kawai T, Nagasu T, Sugi NH, Yoshimatsu K, Yoshino H, Owa T.

Mol Cancer Ther. 2002 Feb;1(4):275-86.

28.

Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.

Nakamura K, Sugumi H, Yamaguchi A, Uenaka T, Kotake Y, Okada T, Kamata J, Niijima J, Nagasu T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.

Mol Cancer Ther. 2002 Jan;1(3):169-75.

30.

Pepsin-resistant 16-kD buckwheat protein is associated with immediate hypersensitivity reaction in patients with buckwheat allergy.

Tanaka K, Matsumoto K, Akasawa A, Nakajima T, Nagasu T, Iikura Y, Saito H.

Int Arch Allergy Immunol. 2002 Sep;129(1):49-56.

PMID:
12372998
31.

Synthesis and biological evaluation of N-(7-indolyl)-3-pyridinesulfonamide derivatives as potent antitumor agents.

Owa T, Yoshino H, Okauchi T, Okabe T, Ozawa Y, Hata Sugi N, Yoshimatsu K, Nagasu T, Koyanagi N, Kitoh K.

Bioorg Med Chem Lett. 2002 Aug 19;12(16):2097-100.

PMID:
12127512
32.

Antitumor activity of ER-51785, a new peptidomimetic inhibitor of farnesyl transferase: synergistic effect in combination with paclitaxel.

Nakamura K, Yamaguchi A, Namiki M, Ishihara H, Nagasu T, Kowalczyk JJ, Garcia AM, Lewis MD, Yoshimatsu K.

Oncol Res. 2001;12(11-12):477-84.

PMID:
11939411
33.

Seizure-mediated accumulation of the beta subunit of Ca2+/calmodulin-dependent protein kinase II in nuclei of mouse brain cells.

Matsu-ura T, Nakadai T, Oda Y, Nagasu T, Mikoshiba K, Tamura TA.

Neurosci Lett. 2002 Apr 12;322(3):149-52.

PMID:
11897160
34.

Identification of activity-regulated proteins in the postsynaptic density fraction.

Satoh K, Takeuchi M, Oda Y, Deguchi-Tawarada M, Sakamoto Y, Matsubara K, Nagasu T, Takai Y.

Genes Cells. 2002 Feb;7(2):187-97.

35.

Anticancer agent E7070 inhibits amino acid and uracil transport in fission yeast.

Tsukahara K, Watanabe T, Hata-Sugi N, Yoshimatsu K, Okayama H, Nagasu T.

Mol Pharmacol. 2001 Dec;60(6):1254-9.

PMID:
11723232
36.

E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo.

Ozawa Y, Sugi NH, Nagasu T, Owa T, Watanabe T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.

Eur J Cancer. 2001 Nov;37(17):2275-82. Erratum in: Eur J Cancer 2002 Mar;38(5):736.

PMID:
11677118
37.

Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents.

Owa T, Yoshino H, Yoshimatsu K, Nagasu T.

Curr Med Chem. 2001 Oct;8(12):1487-503. Review.

PMID:
11562278
38.
39.

Rescue of a transgenic mouse line by transplantation of a frozen-thawed ovary obtained postmortem.

Takahashi E, Miyoshi I, Nagasu T.

Contemp Top Lab Anim Sci. 2001 Jul;40(4):28-31.

PMID:
11451392
40.

Restoration of fertility by transplantation of mouse ovary obtained postmortem.

Takahashi E, Nagasu T.

Contemp Top Lab Anim Sci. 2001 Jan;40(1):36-7.

PMID:
11300675
41.

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

Ino M, Yoshinaga T, Wakamori M, Miyamoto N, Takahashi E, Sonoda J, Kagaya T, Oki T, Nagasu T, Nishizawa Y, Tanaka I, Imoto K, Aizawa S, Koch S, Schwartz A, Niidome T, Sawada K, Mori Y.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5323-8. Epub 2001 Apr 10.

42.

Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome.

Oda Y, Nagasu T, Chait BT.

Nat Biotechnol. 2001 Apr;19(4):379-82.

PMID:
11283599
43.

Schizosaccharomyces pombe och1(+) encodes alpha-1,6-mannosyltransferase that is involved in outer chain elongation of N-linked oligosaccharides.

Yoko-o T, Tsukahara K, Watanabe T, Hata-Sugi N, Yoshimatsu K, Nagasu T, Jigami Y.

FEBS Lett. 2001 Jan 26;489(1):75-80.

44.

A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors.

Owa T, Okauchi T, Yoshimatsu K, Sugi NH, Ozawa Y, Nagasu T, Koyanagi N, Okabe T, Kitoh K, Yoshino H.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1223-6.

PMID:
10866386
46.

Discovery of novel antitumor sulfonamides targeting G1 phase of the cell cycle.

Owa T, Yoshino H, Okauchi T, Yoshimatsu K, Ozawa Y, Sugi NH, Nagasu T, Koyanagi N, Kitoh K.

J Med Chem. 1999 Sep 23;42(19):3789-99.

PMID:
10508428
47.

[Anti tumor activity of farnesyl transferase inhibitor].

Yoshimatsu K, Nagasu T.

Gan To Kagaku Ryoho. 1997 Jan;24(2):145-55. Japanese.

PMID:
9030225
48.

Inhibition of human tumor xenograft growth by treatment with the farnesyl transferase inhibitor B956.

Nagasu T, Yoshimatsu K, Rowell C, Lewis MD, Garcia AM.

Cancer Res. 1995 Nov 15;55(22):5310-4.

49.

In vivo tumor growth inhibition produced by a novel sulfonamide, E7010, against rodent and human tumors.

Koyanagi N, Nagasu T, Fujita F, Watanabe T, Tsukahara K, Funahashi Y, Fujita M, Taguchi T, Yoshino H, Kitoh K.

Cancer Res. 1994 Apr 1;54(7):1702-6.

50.

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