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Items: 1 to 50 of 280

1.

POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33.

Hitomi Y, Ueno K, Kawai Y, Nishida N, Kojima K, Kawashima M, Aiba Y, Nakamura H, Kouno H, Kouno H, Ohta H, Sugi K, Nikami T, Yamashita T, Katsushima S, Komeda T, Ario K, Naganuma A, Shimada M, Hirashima N, Yoshizawa K, Makita F, Furuta K, Kikuchi M, Naeshiro N, Takahashi H, Mano Y, Yamashita H, Matsushita K, Tsunematsu S, Yabuuchi I, Nishimura H, Shimada Y, Yamauchi K, Komatsu T, Sugimoto R, Sakai H, Mita E, Koda M, Nakamura Y, Kamitsukasa H, Sato T, Nakamuta M, Masaki N, Takikawa H, Tanaka A, Ohira H, Zeniya M, Abe M, Kaneko S, Honda M, Arai K, Arinaga-Hino T, Hashimoto E, Taniai M, Umemura T, Joshita S, Nakao K, Ichikawa T, Shibata H, Takaki A, Yamagiwa S, Seike M, Sakisaka S, Takeyama Y, Harada M, Senju M, Yokosuka O, Kanda T, Ueno Y, Ebinuma H, Himoto T, Murata K, Shimoda S, Nagaoka S, Abiru S, Komori A, Migita K, Ito M, Yatsuhashi H, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M.

Sci Rep. 2019 Jan 14;9(1):102. doi: 10.1038/s41598-018-36490-1.

2.

NFKB1 and MANBA Confer Disease-Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants.

Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.

Cell Mol Gastroenterol Hepatol. 2018 Dec 4. pii: S2352-345X(18)30169-3. doi: 10.1016/j.jcmgh.2018.11.006. [Epub ahead of print]

3.

A genome-wide association study identifying RAP1A as a novel susceptibility gene for Crohn's disease in Japanese individuals.

Kakuta Y, Kawai Y, Naito T, Hirano A, Umeno J, Fuyuno Y, Liu Z, Li D, Nakano T, Izumiyama Y, Ichikawa R, Okamoto D, Nagai H, Matsumoto S, Yamamoto K, Yokoyama N, Chiba H, Shimoyama Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Yasuda J, Esaki M, Tokunaga K, Nakamura M, Matsumoto T, McGovern DPB, Nagasaki M, Kinouchi Y, Shimosegawa T, Masamune A.

J Crohns Colitis. 2018 Nov 29. doi: 10.1093/ecco-jcc/jjy197. [Epub ahead of print]

PMID:
30500874
4.

Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare.

Yasuda J, Kinoshita K, Katsuoka F, Danjoh I, Sakurai-Yageta M, Motoike IN, Kuroki Y, Saito S, Kojima K, Shirota M, Saigusa D, Otsuki A, Kawashima J, Yamaguchi-Kabata Y, Tadaka S, Aoki Y, Mimori T, Kumada K, Inoue J, Makino S, Kuriki M, Fuse N, Koshiba S, Tanabe O, Nagasaki M, Tamiya G, Shimizu R, Takai-Igarashi T, Ogishima S, Hozawa A, Kuriyama S, Sugawara J, Tsuboi A, Kiyomoto H, Ishii T, Tomita H, Minegishi N, Suzuki Y, Suzuki K, Kawame H, Tanaka H, Taki Y, Yaegashi N, Kure S, Nagami F; Tohoku Medical Megabank Project Study Group, Kosaki K, Sutoh Y, Hachiya T, Shimizu A, Sasaki M, Yamamoto M.

J Biochem. 2019 Feb 1;165(2):139-158. doi: 10.1093/jb/mvy096.

PMID:
30452759
5.

Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy.

Latt KZ, Honda K, Thiri M, Hitomi Y, Omae Y, Sawai H, Kawai Y, Teraguchi S, Ueno K, Nagasaki M, Mabuchi A, Kaga H, Komatsuda A, Tokunaga K, Noiri E.

Sci Rep. 2018 Oct 22;8(1):15576. doi: 10.1038/s41598-018-33612-7.

6.

Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS).

Kumondai M, Ito A, Hishinuma E, Kikuchi A, Saito T, Takahashi M, Tsukada C, Saito S, Yasuda J, Nagasaki M, Minegishi N, Yamamoto M, Kaneko A, Teramoto I, Kimura M, Hirasawa N, Hiratsuka M.

Drug Metab Pharmacokinet. 2018 Dec;33(6):258-263. doi: 10.1016/j.dmpk.2018.08.003. Epub 2018 Aug 22.

PMID:
30269962
7.

A large-scale study of treatment methods for foreign bodies in the maxillary sinus.

Hara Y, Shiratsuchi H, Tamagawa T, Koshi R, Miya C, Nagasaki M, Ohyama T, Oka S, Sakashita H, Kaneko T.

J Oral Sci. 2018;60(3):321-328. doi: 10.2334/josnusd.18-0109.

8.

Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation.

Watanabe T, Saito T, Rico EMG, Hishinuma E, Kumondai M, Maekawa M, Oda A, Saigusa D, Saito S, Yasuda J, Nagasaki M, Minegishi N, Yamamoto M, Yamaguchi H, Mano N, Hirasawa N, Hiratsuka M.

Biochem Pharmacol. 2018 Oct;156:420-430. doi: 10.1016/j.bcp.2018.09.010. Epub 2018 Sep 8.

PMID:
30201214
9.

Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells.

Kabeya T, Qiu S, Hibino M, Nagasaki M, Kodama N, Iwao T, Matsunaga T.

Drug Metab Dispos. 2018 Oct;46(10):1411-1419. doi: 10.1124/dmd.118.082123. Epub 2018 Aug 1.

PMID:
30068521
10.

Real-world safety and efficacy of omalizumab in patients with severe allergic asthma: A long-term post-marketing study in Japan.

Adachi M, Kozawa M, Yoshisue H, Lee Milligan K, Nagasaki M, Sasajima T, Miyamoto T, Ohta K.

Respir Med. 2018 Aug;141:56-63. doi: 10.1016/j.rmed.2018.06.021. Epub 2018 Jun 28.

PMID:
30053973
11.

Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project.

Yasuda J, Katsuoka F, Danjoh I, Kawai Y, Kojima K, Nagasaki M, Saito S, Yamaguchi-Kabata Y, Tadaka S, Motoike IN, Kumada K, Sakurai-Yageta M, Tanabe O, Fuse N, Tamiya G, Higasa K, Matsuda F, Yasuda N, Iwasaki M, Sasaki M, Shimizu A, Kinoshita K, Yamamoto M.

BMC Genomics. 2018 Jul 24;19(1):551. doi: 10.1186/s12864-018-4942-0.

12.

Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population.

Jia X, Horinouchi T, Hitomi Y, Shono A, Khor SS, Omae Y, Kojima K, Kawai Y, Nagasaki M, Kaku Y, Okamoto T, Ohwada Y, Ohta K, Okuda Y, Fujimaru R, Hatae K, Kumagai N, Sawanobori E, Nakazato H, Ohtsuka Y, Nakanishi K, Shima Y, Tanaka R, Ashida A, Kamei K, Ishikura K, Nozu K, Tokunaga K, Iijima K; Research Consortium on Genetics of Childhood Idiopathic Nephrotic Syndrome in Japan.

J Am Soc Nephrol. 2018 Aug;29(8):2189-2199. doi: 10.1681/ASN.2017080859. Epub 2018 Jul 16.

PMID:
30012571
13.

NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.

Kakuta Y, Kawai Y, Okamoto D, Takagawa T, Ikeya K, Sakuraba H, Nishida A, Nakagawa S, Miura M, Toyonaga T, Onodera K, Shinozaki M, Ishiguro Y, Mizuno S, Takahara M, Yanai S, Hokari R, Nakagawa T, Araki H, Motoya S, Naito T, Moroi R, Shiga H, Endo K, Kobayashi T, Naganuma M, Hiraoka S, Matsumoto T, Nakamura S, Nakase H, Hisamatsu T, Sasaki M, Hanai H, Andoh A, Nagasaki M, Kinouchi Y, Shimosegawa T, Masamune A, Suzuki Y; MENDEL study group.

J Gastroenterol. 2018 Jun 19. doi: 10.1007/s00535-018-1486-7. [Epub ahead of print]

14.

Author Correction: Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse.

Ueno K, Iwagawa T, Ochiai G, Koso H, Nakauchi H, Nagasaki M, Suzuki Y, Watanabe S.

Sci Rep. 2018 Jun 7;8(1):8946. doi: 10.1038/s41598-018-27041-9.

15.

Population-scale whole genome sequencing identifies 271 highly polymorphic short tandem repeats from Japanese population.

Hirata S, Kojima K, Misawa K, Gervais O, Kawai Y, Nagasaki M.

Heliyon. 2018 May 22;4(5):e00625. doi: 10.1016/j.heliyon.2018.e00625. eCollection 2018 May.

16.

NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.

Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M.

Sci Rep. 2018 May 23;8(1):8071. doi: 10.1038/s41598-018-26369-6.

17.

Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals.

Hishinuma E, Narita Y, Saito S, Maekawa M, Akai F, Nakanishi Y, Yasuda J, Nagasaki M, Yamamoto M, Yamaguchi H, Mano N, Hirasawa N, Hiratsuka M.

Drug Metab Dispos. 2018 Aug;46(8):1083-1090. doi: 10.1124/dmd.118.081737. Epub 2018 May 16.

PMID:
29769267
18.

Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project.

Koshiba S, Motoike I, Saigusa D, Inoue J, Shirota M, Katoh Y, Katsuoka F, Danjoh I, Hozawa A, Kuriyama S, Minegishi N, Nagasaki M, Takai-Igarashi T, Ogishima S, Fuse N, Kure S, Tamiya G, Tanabe O, Yasuda J, Kinoshita K, Yamamoto M.

Genes Cells. 2018 Jun;23(6):406-417. doi: 10.1111/gtc.12588. Epub 2018 Apr 27. Review.

19.

Convergent Synthesis of a Bisecting N-Acetylglucosamine (GlcNAc)-Containing N-Glycan.

Manabe Y, Shomura H, Minamoto N, Nagasaki M, Takakura Y, Tanaka K, Silipo A, Molinaro A, Fukase K.

Chem Asian J. 2018 Jun 18;13(12):1544-1551. doi: 10.1002/asia.201800367. Epub 2018 May 25.

PMID:
29665315
20.

Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.

Naito T, Yokoyama N, Kakuta Y, Ueno K, Kawai Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Nagasaki M, Masamune A, Kinouchi Y, Shimosegawa T.

J Gastroenterol Hepatol. 2018 Nov;33(11):1873-1881. doi: 10.1111/jgh.14149. Epub 2018 May 8.

PMID:
29603369
21.

Continuous application of compressive force induces fusion of osteoclast-like RAW264.7 cells via upregulation of RANK and downregulation of LGR4.

Matsuike R, Tanaka H, Nakai K, Kanda M, Nagasaki M, Murakami F, Shibata C, Mayahara K, Nakajima A, Tanabe N, Kawato T, Maeno M, Shimizu N.

Life Sci. 2018 May 15;201:30-36. doi: 10.1016/j.lfs.2018.03.038. Epub 2018 Mar 20.

PMID:
29572179
22.

Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease.

Chiba H, Kakuta Y, Kinouchi Y, Kawai Y, Watanabe K, Nagao M, Naito T, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Nagasaki M, Unno M, Shimosegawa T.

PLoS One. 2018 Mar 16;13(3):e0194036. doi: 10.1371/journal.pone.0194036. eCollection 2018.

23.

Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing.

Mimori T, Yasuda J, Kuroki Y, Shibata TF, Katsuoka F, Saito S, Nariai N, Ono A, Nakai-Inagaki N, Misawa K, Tateno K, Kawai Y, Fuse N, Hozawa A, Kuriyama S, Sugawara J, Minegishi N, Suzuki K, Kinoshita K, Nagasaki M, Yamamoto M.

Pharmacogenomics J. 2018 Jan 19. doi: 10.1038/s41397-017-0010-4. [Epub ahead of print]

PMID:
29352165
24.

Identification of somatic mutations in postmortem human brains by whole genome sequencing and their implications for psychiatric disorders.

Nishioka M, Bundo M, Ueda J, Katsuoka F, Sato Y, Kuroki Y, Ishii T, Ukai W, Murayama S, Hashimoto E, Nagasaki M, Yasuda J, Kasai K, Kato T, Iwamoto K.

Psychiatry Clin Neurosci. 2018 Apr;72(4):280-294. doi: 10.1111/pcn.12632. Epub 2018 Feb 10.

PMID:
29283202
25.

Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies.

Hachiya T, Furukawa R, Shiwa Y, Ohmomo H, Ono K, Katsuoka F, Nagasaki M, Yasuda J, Fuse N, Kinoshita K, Yamamoto M, Tanno K, Satoh M, Endo R, Sasaki M, Sakata K, Kobayashi S, Ogasawara K, Hitomi J, Sobue K, Shimizu A.

NPJ Genom Med. 2017 Apr 13;2:11. doi: 10.1038/s41525-017-0016-5. eCollection 2017.

26.

Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7.

Shiga Y, Nishiguchi KM, Kawai Y, Kojima K, Sato K, Fujita K, Takahashi M, Omodaka K, Araie M, Kashiwagi K, Aihara M, Iwata T, Mabuchi F, Takamoto M, Ozaki M, Kawase K, Fuse N, Yamamoto M, Yasuda J, Nagasaki M, Nakazawa T; Japan Glaucoma Society Omics Group (JGS-OG).

PLoS One. 2017 Dec 20;12(12):e0186678. doi: 10.1371/journal.pone.0186678. eCollection 2017.

27.

Evaluation of reported pathogenic variants and their frequencies in a Japanese population based on a whole-genome reference panel of 2049 individuals.

Yamaguchi-Kabata Y, Yasuda J, Tanabe O, Suzuki Y, Kawame H, Fuse N, Nagasaki M, Kawai Y, Kojima K, Katsuoka F, Saito S, Danjoh I, Motoike IN, Yamashita R, Koshiba S, Saigusa D, Tamiya G, Kure S, Yaegashi N, Kawaguchi Y, Nagami F, Kuriyama S, Sugawara J, Minegishi N, Hozawa A, Ogishima S, Kiyomoto H, Takai-Igarashi T; ToMMo Study Group, Kinoshita K, Yamamoto M.

J Hum Genet. 2018 Feb;63(2):213-230. doi: 10.1038/s10038-017-0347-1. Epub 2017 Dec 1.

PMID:
29192238
28.

Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing.

Shibuya Y, Tokunaga H, Saito S, Shimokawa K, Katsuoka F, Bin L, Kojima K, Nagasaki M, Yamamoto M, Yaegashi N, Yasuda J.

Genes Chromosomes Cancer. 2018 Feb;57(2):51-60. doi: 10.1002/gcc.22507. Epub 2017 Oct 30.

PMID:
29044863
29.

Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design.

Takai-Igarashi T, Kinoshita K, Nagasaki M, Ogishima S, Nakamura N, Nagase S, Nagaie S, Saito T, Nagami F, Minegishi N, Suzuki Y, Suzuki K, Hashizume H, Kuriyama S, Hozawa A, Yaegashi N, Kure S, Tamiya G, Kawaguchi Y, Tanaka H, Yamamoto M.

BMC Med Inform Decis Mak. 2017 Jul 6;17(1):100. doi: 10.1186/s12911-017-0494-5.

30.

Hypomorphic A20 expression confers susceptibility to psoriasis.

Aki A, Nagasaki M, Malynn BA, Ma A, Kagari T.

PLoS One. 2017 Jun 28;12(6):e0180481. doi: 10.1371/journal.pone.0180481. eCollection 2017.

31.

Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse.

Ueno K, Iwagawa T, Ochiai G, Koso H, Nakauchi H, Nagasaki M, Suzuki Y, Watanabe S.

Sci Rep. 2017 Jun 15;7(1):3578. doi: 10.1038/s41598-017-03874-8. Erratum in: Sci Rep. 2018 Jun 7;8(1):8946.

32.

Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis.

Hitomi Y, Kojima K, Kawashima M, Kawai Y, Nishida N, Aiba Y, Yasunami M, Nagasaki M, Nakamura M, Tokunaga K.

Sci Rep. 2017 Jun 6;7(1):2904. doi: 10.1038/s41598-017-03067-3.

33.

A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients.

Hamanaka T, Kimura M, Sakurai T, Ishida N, Yasuda J, Nagasaki M, Nariai N, Endo A, Homma K, Katsuoka F, Matsubara Y, Yamamoto M, Fuse N.

Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2818-2831. doi: 10.1167/iovs.16-20646.

PMID:
28564705
34.

Alpine Skiing as Winter-Time High-Intensity Training.

Stöggl TL, Schwarzl C, Müller EE, Nagasaki M, Stöggl J, Schönfelder M, Niebauer J.

Med Sci Sports Exerc. 2017 Sep;49(9):1859-1867. doi: 10.1249/MSS.0000000000001289.

PMID:
28398944
35.

LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients.

Liu TC, Naito T, Liu Z, VanDussen KL, Haritunians T, Li D, Endo K, Kawai Y, Nagasaki M, Kinouchi Y, McGovern DP, Shimosegawa T, Kakuta Y, Stappenbeck TS.

JCI Insight. 2017 Mar 23;2(6):e91917. doi: 10.1172/jci.insight.91917.

36.

Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.

Matsuura K, Sawai H, Ikeo K, Ogawa S, Iio E, Isogawa M, Shimada N, Komori A, Toyoda H, Kumada T, Namisaki T, Yoshiji H, Sakamoto N, Nakagawa M, Asahina Y, Kurosaki M, Izumi N, Enomoto N, Kusakabe A, Kajiwara E, Itoh Y, Ide T, Tamori A, Matsubara M, Kawada N, Shirabe K, Tomita E, Honda M, Kaneko S, Nishina S, Suetsugu A, Hiasa Y, Watanabe H, Genda T, Sakaida I, Nishiguchi S, Takaguchi K, Tanaka E, Sugihara J, Shimada M, Kondo Y, Kawai Y, Kojima K, Nagasaki M, Tokunaga K, Tanaka Y; Japanese Genome-Wide Association Study Group for Viral Hepatitis.

Gastroenterology. 2017 May;152(6):1383-1394. doi: 10.1053/j.gastro.2017.01.041. Epub 2017 Feb 3.

37.

Genome-wide association study using the ethnicity-specific Japonica array: identification of new susceptibility loci for cold medicine-related Stevens-Johnson syndrome with severe ocular complications.

Ueta M, Sawai H, Shingaki R, Kawai Y, Sotozono C, Kojima K, Yoon KC, Kim MK, Seo KY, Joo CK, Nagasaki M, Kinoshita S, Tokunaga K.

J Hum Genet. 2017 Apr;62(4):485-489. doi: 10.1038/jhg.2016.160. Epub 2017 Jan 19.

PMID:
28100913
38.

Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.

Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Nakamura H, Tanaka A, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Abe M, Nakao K, Yamagiwa S, Kaneko S, Honda M, Umemura T, Ichida T, Seike M, Sakisaka S, Harada M, Yokosuka O, Ueno Y, Senju M, Kanda T, Shibata H, Himoto T, Murata K, Miyake Y, Ebinuma H, Taniai M, Joshita S, Nikami T, Ota H, Kouno H, Kouno H, Nakamuta M, Fukushima N, Kohjima M, Komatsu T, Komeda T, Ohara Y, Muro T, Yamashita T, Yoshizawa K, Nakamura Y, Shimada M, Hirashima N, Sugi K, Ario K, Takesaki E, Naganuma A, Mano H, Yamashita H, Matsushita K, Yamauchi K, Makita F, Nishimura H, Furuta K, Takahashi N, Kikuchi M, Masaki N, Tanaka T, Tamura S, Mori A, Yagi S, Shirabe K, Komori A, Migita K, Ito M, Nagaoka S, Abiru S, Yatsuhashi H, Yasunami M, Shimoda S, Harada K, Egawa H, Maehara Y, Uemoto S, Kokudo N, Takikawa H, Ishibashi H, Chayama K, Mizokami M, Nagasaki M, Tokunaga K, Nakamura M.

Hum Mol Genet. 2017 Feb 1;26(3):650-659. doi: 10.1093/hmg/ddw406.

PMID:
28062665
39.

STR-realigner: a realignment method for short tandem repeat regions.

Kojima K, Kawai Y, Misawa K, Mimori T, Nagasaki M.

BMC Genomics. 2016 Dec 3;17(1):991.

40.

Discovery and pharmacological effects of a novel GPR142 antagonist.

Murakoshi M, Kuwabara H, Nagasaki M, Xiong YM, Reagan JD, Maeda H, Nara F.

J Recept Signal Transduct Res. 2017 Jun;37(3):290-296. doi: 10.1080/10799893.2016.1247861. Epub 2016 Nov 3.

PMID:
27807998
41.

Chemical Synthesis of a Complex-Type N-Glycan Containing a Core Fucose.

Nagasaki M, Manabe Y, Minamoto N, Tanaka K, Silipo A, Molinaro A, Fukase K.

J Org Chem. 2016 Nov 18;81(22):10600-10616. Epub 2016 Oct 27.

PMID:
27775350
42.

AP-SKAT: highly-efficient genome-wide rare variant association test.

Hasegawa T, Kojima K, Kawai Y, Misawa K, Mimori T, Nagasaki M.

BMC Genomics. 2016 Sep 21;17(1):745.

43.

Short tandem repeat number estimation from paired-end reads for multiple individuals by considering coalescent tree.

Kojima K, Kawai Y, Nariai N, Mimori T, Hasegawa T, Nagasaki M.

BMC Genomics. 2016 Aug 31;17 Suppl 5:494. doi: 10.1186/s12864-016-2821-0.

44.

The structural origin of metabolic quantitative diversity.

Koshiba S, Motoike I, Kojima K, Hasegawa T, Shirota M, Saito T, Saigusa D, Danjoh I, Katsuoka F, Ogishima S, Kawai Y, Yamaguchi-Kabata Y, Sakurai M, Hirano S, Nakata J, Motohashi H, Hozawa A, Kuriyama S, Minegishi N, Nagasaki M, Takai-Igarashi T, Fuse N, Kiyomoto H, Sugawara J, Suzuki Y, Kure S, Yaegashi N, Tanabe O, Kinoshita K, Yasuda J, Yamamoto M.

Sci Rep. 2016 Aug 16;6:31463. doi: 10.1038/srep31463.

45.

Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.

Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J.

Sci Rep. 2016 Aug 10;6:31429. doi: 10.1038/srep31429.

46.

Conditional rod photoreceptor ablation reveals Sall1 as a microglial marker and regulator of microglial morphology in the retina.

Koso H, Tsuhako A, Lai CY, Baba Y, Otsu M, Ueno K, Nagasaki M, Suzuki Y, Watanabe S.

Glia. 2016 Nov;64(11):2005-24. doi: 10.1002/glia.23038. Epub 2016 Jul 26.

PMID:
27459098
47.

Variants in the UBR1 gene are not associated with chronic pancreatitis in Japan.

Masamune A, Nakano E, Niihori T, Hamada S, Nagasaki M, Aoki Y, Shimosegawa T.

Pancreatology. 2016 Sep-Oct;16(5):814-8. doi: 10.1016/j.pan.2016.06.662. Epub 2016 Jul 2.

PMID:
27397733
48.

Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation.

Ueno K, Iwagawa T, Kuribayashi H, Baba Y, Nakauchi H, Murakami A, Nagasaki M, Suzuki Y, Watanabe S.

Sci Rep. 2016 Jul 5;6:29264. doi: 10.1038/srep29264.

49.

The Tohoku Medical Megabank Project: Design and Mission.

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