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Items: 27

1.

S100A8/A9 in Myocardial Infarction.

Sreejit G, Nooti SK, Athmanathan B, Nagareddy PR.

Methods Mol Biol. 2019;1929:739-754. doi: 10.1007/978-1-4939-9030-6_46.

PMID:
30710308
2.

Chronic sympathetic driven hypertension promotes atherosclerosis by enhancing hematopoiesis.

Al-Sharea A, Lee MKS, Whillas A, Michell DL, Shihata WA, Nicholls AJ, Cooney OD, Kraakman MJ, Veiga CB, Jefferis AM, Jackson K, Nagareddy PR, Lambert G, Wong CHY, Andrews KL, Head GA, Chin-Dusting J, Murphy AJ.

Haematologica. 2019 Mar;104(3):456-467. doi: 10.3324/haematol.2018.192898. Epub 2018 Oct 25.

3.

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.

Dragoljevic D, Kraakman MJ, Nagareddy PR, Ngo D, Shihata W, Kammoun HL, Whillas A, Lee MKS, Al-Sharea A, Pernes G, Flynn MC, Lancaster GI, Febbraio MA, Chin-Dusting J, Hanaoka BY, Wicks IP, Murphy AJ.

Eur Heart J. 2018 Jun 14;39(23):2158-2167. doi: 10.1093/eurheartj/ehy119.

PMID:
29905812
4.

Rad GTPase deletion attenuates post-ischemic cardiac dysfunction and remodeling.

Manning JR, Chelvarajan L, Levitan BM, Withers CN, Nagareddy PR, Haggerty CM, Fornwalt BK, Gao E, Tripathi H, Abdel-Latif A, Andres DA, Satin J.

JACC Basic Transl Sci. 2018 Feb;3(1):83-96. doi: 10.1016/j.jacbts.2017.09.004.

5.

It's reticulated: the liver at the heart of atherosclerosis.

Nagareddy PR, Noothi SK, Flynn MC, Murphy AJ.

J Endocrinol. 2018 Jul;238(1):R1-R11. doi: 10.1530/JOE-18-0082. Epub 2018 May 2. Review.

PMID:
29720539
6.

SGLT2 inhibition reduces atherosclerosis by enhancing lipoprotein clearance in Ldlr-/- type 1 diabetic mice.

Al-Sharea A, Murphy AJ, Huggins LA, Hu Y, Goldberg IJ, Nagareddy PR.

Atherosclerosis. 2018 Apr;271:166-176. doi: 10.1016/j.atherosclerosis.2018.02.028. Epub 2018 Mar 2.

PMID:
29518749
7.

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.

Kraakman MJ, Lee MK, Al-Sharea A, Dragoljevic D, Barrett TJ, Montenont E, Basu D, Heywood S, Kammoun HL, Flynn M, Whillas A, Hanssen NM, Febbraio MA, Westein E, Fisher EA, Chin-Dusting J, Cooper ME, Berger JS, Goldberg IJ, Nagareddy PR, Murphy AJ.

J Clin Invest. 2017 Jun 1;127(6):2133-2147. doi: 10.1172/JCI92450. Epub 2017 May 15.

8.

Pharmacological Elevation of Circulating Bioactive Phosphosphingolipids Enhances Myocardial Recovery After Acute Infarction.

Klyachkin YM, Nagareddy PR, Ye S, Wysoczynski M, Asfour A, Gao E, Sunkara M, Brandon JA, Annabathula R, Ponnapureddy R, Solanki M, Pervaiz ZH, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A.

Stem Cells Transl Med. 2015 Nov;4(11):1333-43. doi: 10.5966/sctm.2014-0273. Epub 2015 Sep 14.

9.

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.

Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, Tall AR, Goldberg IJ, Murphy AJ.

Cell Metab. 2014 May 6;19(5):821-35. doi: 10.1016/j.cmet.2014.03.029.

10.

A novel role for bioactive lipids in stem cell mobilization during cardiac ischemia: new paradigms in thrombosis: novel mediators and biomarkers.

Nagareddy PR, Asfour A, Klyachkin YM, Abdel-Latif A.

J Thromb Thrombolysis. 2014 Jan;37(1):24-31. doi: 10.1007/s11239-013-1032-7. Review.

11.

Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children.

Tolani S, Pagler TA, Murphy AJ, Bochem AE, Abramowicz S, Welch C, Nagareddy PR, Holleran S, Hovingh GK, Kuivenhoven JA, Tall AR.

Atherosclerosis. 2013 Jul;229(1):79-85. doi: 10.1016/j.atherosclerosis.2013.03.031. Epub 2013 Apr 19.

12.

Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis.

Nagareddy PR, Murphy AJ, Stirzaker RA, Hu Y, Yu S, Miller RG, Ramkhelawon B, Distel E, Westerterp M, Huang LS, Schmidt AM, Orchard TJ, Fisher EA, Tall AR, Goldberg IJ.

Cell Metab. 2013 May 7;17(5):695-708. doi: 10.1016/j.cmet.2013.04.001.

13.

Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.

Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR.

Circ Res. 2013 May 24;112(11):1456-65. doi: 10.1161/CIRCRESAHA.113.301086. Epub 2013 Apr 9.

14.

Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway.

Goldberg IJ, Huang LS, Huggins LA, Yu S, Nagareddy PR, Scanlan TS, Ehrenkranz JR.

Endocrinology. 2012 Nov;153(11):5143-9. doi: 10.1210/en.2012-1572. Epub 2012 Sep 4.

15.

Inhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin-resistant rats.

Nagareddy PR, Rajput PS, Vasudevan H, McClure B, Kumar U, Macleod KM, McNeill JH.

Br J Pharmacol. 2012 Feb;165(3):705-15. doi: 10.1111/j.1476-5381.2011.01583.x.

16.

GPCR agonist-induced transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin-resistant rats.

Nagareddy PR, MacLeod KM, McNeill JH.

Cardiovasc Res. 2010 Jul 1;87(1):177-86. doi: 10.1093/cvr/cvq030. Epub 2010 Jan 28.

PMID:
20110336
17.

Selective inhibition of protein kinase C beta(2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats.

Nagareddy PR, Soliman H, Lin G, Rajput PS, Kumar U, McNeill JH, MacLeod KM.

Diabetes. 2009 Oct;58(10):2355-64. doi: 10.2337/db09-0432. Epub 2009 Jul 8.

18.

Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis.

Nagareddy PR, Chow FL, Hao L, Wang X, Nishimura T, MacLeod KM, McNeill JH, Fernandez-Patron C.

Cardiovasc Res. 2009 Dec 1;84(3):368-77. doi: 10.1093/cvr/cvp230. Epub 2009 Jul 3.

PMID:
19578070
19.

Chronic inhibition of inducible nitric oxide synthase ameliorates cardiovascular abnormalities in streptozotocin diabetic rats.

Nagareddy PR, McNeill JH, MacLeod KM.

Eur J Pharmacol. 2009 Jun 2;611(1-3):53-9. doi: 10.1016/j.ejphar.2009.03.061. Epub 2009 Apr 1.

PMID:
19344709
20.

N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats.

Xia Z, Kuo KH, Nagareddy PR, Wang F, Guo Z, Guo T, Jiang J, McNeill JH.

Cardiovasc Res. 2007 Mar 1;73(4):770-82. Epub 2006 Nov 30.

PMID:
17250813
21.

Antioxidant N-acetylcysteine restores myocardial Mn-SOD activity and attenuates myocardial dysfunction in diabetic rats.

Xia Z, Guo Z, Nagareddy PR, Yuen V, Yeung E, McNeill JH.

Eur J Pharmacol. 2006 Aug 21;544(1-3):118-25. Epub 2006 Jun 23.

PMID:
16859669
22.

Gonadectomy prevents endothelial dysfunction in fructose-fed male rats, a factor contributing to the development of hypertension.

Vasudevan H, Nagareddy PR, McNeill JH.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H3058-64. Epub 2006 Jun 30.

23.

N-acetylcysteine prevents nitrosative stress-associated depression of blood pressure and heart rate in streptozotocin diabetic rats.

Nagareddy PR, Xia Z, MacLeod KM, McNeill JH.

J Cardiovasc Pharmacol. 2006 Apr;47(4):513-20.

PMID:
16680064
24.

Withania somnifera improves bone calcification in calcium-deficient ovariectomized rats.

Nagareddy PR, Lakshmana M.

J Pharm Pharmacol. 2006 Apr;58(4):513-9.

PMID:
16597369
25.
26.

Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes.

Nagareddy PR, Xia Z, McNeill JH, MacLeod KM.

Am J Physiol Heart Circ Physiol. 2005 Nov;289(5):H2144-52. Epub 2005 Jul 8.

27.

Oral administration of sodium tungstate improves cardiac performance in streptozotocin-induced diabetic rats.

Nagareddy PR, Vasudevan H, McNeill JH.

Can J Physiol Pharmacol. 2005 May;83(5):405-11.

PMID:
15897922

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