Sort by
Items per page

Send to

Choose Destination

Search results

Items: 33


Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice.

Allen J 4th, Gyorke CE, Tripathy MK, Zhang Y, Lovett A, Montgomery SA, Nagarajan UM.

Infect Immun. 2019 Jul 23;87(8). pii: e00262-19. doi: 10.1128/IAI.00262-19. Print 2019 Aug.


T Cell-Independent Gamma Interferon and B Cells Cooperate To Prevent Mortality Associated with Disseminated Chlamydia muridarum Genital Tract Infection.

Poston TB, O'Connell CM, Girardi J, Sullivan JE, Nagarajan UM, Marinov A, Scurlock AM, Darville T.

Infect Immun. 2018 Jun 21;86(7). pii: e00143-18. doi: 10.1128/IAI.00143-18. Print 2018 Jul.


Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease.

Zheng X, O'Connell CM, Zhong W, Nagarajan UM, Tripathy M, Lee D, Russell AN, Wiesenfeld H, Hillier S, Darville T.

J Immunol. 2018 Apr 15;200(8):2941-2956. doi: 10.4049/jimmunol.1701658. Epub 2018 Mar 12.


Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp.

Nagarajan UM, Tripathy M, Kollipara A, Allen J 4th, Goodwin A, Whittimore J, Wyrick PB, Rank RG.

Immunol Cell Biol. 2018 Mar;96(3):246-256. doi: 10.1111/imcb.1033. Epub 2018 Jan 6.


A Chlamydia-Specific TCR-Transgenic Mouse Demonstrates Th1 Polyfunctionality with Enhanced Effector Function.

Poston TB, Qu Y, Girardi J, O'Connell CM, Frazer LC, Russell AN, Wall M, Nagarajan UM, Darville T.

J Immunol. 2017 Oct 15;199(8):2845-2854. doi: 10.4049/jimmunol.1700914. Epub 2017 Aug 30.


Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice.

Ahmed M, Jiao H, Domingo-Gonzalez R, Das S, Griffiths KL, Rangel-Moreno J, Nagarajan UM, Khader SA.

J Leukoc Biol. 2017 Jun;101(6):1373-1381. doi: 10.1189/jlb.4A0616-270R. Epub 2017 Mar 3.


Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

Finethy R, Jorgensen I, Haldar AK, de Zoete MR, Strowig T, Flavell RA, Yamamoto M, Nagarajan UM, Miao EA, Coers J.

Infect Immun. 2015 Dec;83(12):4740-9. doi: 10.1128/IAI.00856-15. Epub 2015 Sep 28.


The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection.

Zhang Y, Yeruva L, Marinov A, Prantner D, Wyrick PB, Lupashin V, Nagarajan UM.

J Immunol. 2014 Sep 1;193(5):2394-404. doi: 10.4049/jimmunol.1302718. Epub 2014 Jul 28.


IL-12 secretion by Langerhans cells stimulated with Candida skin test reagent is mediated by dectin-1 in some healthy individuals.

Nakagawa M, Coleman HN, Wang X, Daniels J, Sikes J, Nagarajan UM.

Cytokine. 2014 Feb;65(2):202-9. doi: 10.1016/j.cyto.2013.11.002. Epub 2013 Dec 2.


CD4+ T cell expression of MyD88 is essential for normal resolution of Chlamydia muridarum genital tract infection.

Frazer LC, Sullivan JE, Zurenski MA, Mintus M, Tomasak TE, Prantner D, Nagarajan UM, Darville T.

J Immunol. 2013 Oct 15;191(8):4269-79. doi: 10.4049/jimmunol.1301547. Epub 2013 Sep 13.


Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection.

Nagarajan UM, Sikes JD, Yeruva L, Prantner D.

J Immunol. 2012 Mar 15;188(6):2866-75. doi: 10.4049/jimmunol.1103461. Epub 2012 Feb 13.


Chlamydia trachomatis hijacks intra-Golgi COG complex-dependent vesicle trafficking pathway.

Pokrovskaya ID, Szwedo JW, Goodwin A, Lupashina TV, Nagarajan UM, Lupashin VV.

Cell Microbiol. 2012 May;14(5):656-68. doi: 10.1111/j.1462-5822.2012.01747.x. Epub 2012 Feb 15.


Interferon regulatory transcription factor 3 protects mice from uterine horn pathology during Chlamydia muridarum genital infection.

Prantner D, Sikes JD, Hennings L, Savenka AV, Basnakian AG, Nagarajan UM.

Infect Immun. 2011 Oct;79(10):3922-33. doi: 10.1128/IAI.00140-11. Epub 2011 Jul 25.


Essential role for neutrophils in pathogenesis and adaptive immunity in Chlamydia caviae ocular infections.

Lacy HM, Bowlin AK, Hennings L, Scurlock AM, Nagarajan UM, Rank RG.

Infect Immun. 2011 May;79(5):1889-97. doi: 10.1128/IAI.01257-10. Epub 2011 Mar 14.


Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection.

Prantner D, Darville T, Nagarajan UM.

J Immunol. 2010 Mar 1;184(5):2551-60. doi: 10.4049/jimmunol.0903704. Epub 2010 Jan 27.


Host chemokine and cytokine response in the endocervix within the first developmental cycle of Chlamydia muridarum.

Rank RG, Lacy HM, Goodwin A, Sikes J, Whittimore J, Wyrick PB, Nagarajan UM.

Infect Immun. 2010 Jan;78(1):536-44. doi: 10.1128/IAI.00772-09. Epub 2009 Oct 19.


Critical role for interleukin-1beta (IL-1beta) during Chlamydia muridarum genital infection and bacterial replication-independent secretion of IL-1beta in mouse macrophages.

Prantner D, Darville T, Sikes JD, Andrews CW Jr, Brade H, Rank RG, Nagarajan UM.

Infect Immun. 2009 Dec;77(12):5334-46. doi: 10.1128/IAI.00883-09. Epub 2009 Oct 5.


Effect of Chlamydiaphage phiCPG1 on the course of conjunctival infection with "Chlamydia caviae" in guinea pigs.

Rank RG, Bowlin AK, Cané S, Shou H, Liu Z, Nagarajan UM, Bavoil PM.

Infect Immun. 2009 Mar;77(3):1216-21. doi: 10.1128/IAI.01109-08. Epub 2009 Jan 12.


Role for the chlamydial type III secretion apparatus in host cytokine expression.

Prantner D, Nagarajan UM.

Infect Immun. 2009 Jan;77(1):76-84. doi: 10.1128/IAI.00963-08. Epub 2008 Oct 13.


Type I interferon signaling exacerbates Chlamydia muridarum genital infection in a murine model.

Nagarajan UM, Prantner D, Sikes JD, Andrews CW Jr, Goodwin AM, Nagarajan S, Darville T.

Infect Immun. 2008 Oct;76(10):4642-8. doi: 10.1128/IAI.00629-08. Epub 2008 Jul 28.


Conserved residues of the bare lymphocyte syndrome transcription factor RFXAP determine coordinate MHC class II expression.

Long AB, Ferguson AM, Majumder P, Nagarajan UM, Boss JM.

Mol Immunol. 2006 Feb;43(5):395-409. Epub 2005 Apr 12.


X box-like sequences in the MHC class II region maintain regulatory function.

Gomez JA, Majumder P, Nagarajan UM, Boss JM.

J Immunol. 2005 Jul 15;175(2):1030-40.


Molecular characterization of guinea - pig (Cavia porcellus) CD8alpha and CD8beta cDNA.

Nagarajan UM, O'Connell C, Rank RG.

Tissue Antigens. 2004 Feb;63(2):184-9.


Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection.

Darville T, O'Neill JM, Andrews CW Jr, Nagarajan UM, Stahl L, Ojcius DM.

J Immunol. 2003 Dec 1;171(11):6187-97.


Modulation of gene expression by the MHC class II transactivator.

Nagarajan UM, Bushey A, Boss JM.

J Immunol. 2002 Nov 1;169(9):5078-88.


Class II transactivator is required for maximal expression of HLA-DOB in B cells.

Nagarajan UM, Lochamy J, Chen X, Beresford GW, Nilsen R, Jensen PE, Boss JM.

J Immunol. 2002 Feb 15;168(4):1780-6.


Associations and interactions between bare lymphocyte syndrome factors.

DeSandro AM, Nagarajan UM, Boss JM.

Mol Cell Biol. 2000 Sep;20(17):6587-99.


Novel mutations within the RFX-B gene and partial rescue of MHC and related genes through exogenous class II transactivator in RFX-B-deficient cells.

Nagarajan UM, Peijnenburg A, Gobin SJ, Boss JM, van den elsen PJ.

J Immunol. 2000 Apr 1;164(7):3666-74.


The bare lymphocyte syndrome: molecular clues to the transcriptional regulation of major histocompatibility complex class II genes.

DeSandro A, Nagarajan UM, Boss JM.

Am J Hum Genet. 1999 Aug;65(2):279-86. Review. No abstract available.


RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency.

Nagarajan UM, Louis-Plence P, DeSandro A, Nilsen R, Bushey A, Boss JM.

Immunity. 1999 Feb;10(2):153-62. Erratum in: Immunity 1999 Mar;10(3):399.

Supplemental Content

Loading ...
Support Center