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Items: 27

1.

Odanacatib Restores Trabecular Bone of Skeletally Mature Female Rabbits With Osteopenia but Induces Brittleness of Cortical Bone: A Comparative Study of the Investigational Drug With PTH, Estrogen, and Alendronate.

Khan MP, Singh AK, Singh AK, Shrivastava P, Tiwari MC, Nagar GK, Bora HK, Parameswaran V, Sanyal S, Bellare JR, Chattopadhyay N.

J Bone Miner Res. 2018 Nov;33(11):2084-2085. doi: 10.1002/jbmr.3536. Epub 2018 Jul 26. No abstract available.

2.

M2 polarization of macrophages by Oncostatin M in hypoxic tumor microenvironment is mediated by mTORC2 and promotes tumor growth and metastasis.

Shrivastava R, Asif M, Singh V, Dubey P, Ahmad Malik S, Lone MU, Tewari BN, Baghel KS, Pal S, Nagar GK, Chattopadhyay N, Bhadauria S.

Cytokine. 2019 Jun;118:130-143. doi: 10.1016/j.cyto.2018.03.032. Epub 2018 Apr 3.

PMID:
29625858
3.

Influence of antifertility agents Dutasteride and Nifedipine on CatSper gene level in epididymis during sperm maturation in BALB/c mice.

Srivastav A, Changkija B, Sharan K, Nagar GK, Bansode FW.

Reproduction. 2018 Apr;155(4):347-359. doi: 10.1530/REP-17-0664. Epub 2018 Feb 6.

PMID:
29434054
4.

Erratum. Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia. Diabetes 2015;64:2609-2623.

Khan MP, Singh AK, Joharapurkar AA, Yadav M, Shree S, Kumar H, Gurjar A, Mishra JS, Tiwari MC, Nagar GK, Kumar S, Ramachandran R, Sharan A, Jain MR, Trivedi AK, Maurya R, Godbole MM, Gayen JR, Sanyal S, Chattopadhyay N.

Diabetes. 2017 Dec;66(12):3142-3143. doi: 10.2337/db17-er12b. Epub 2017 Oct 5. No abstract available.

5.

Heartwood extract from Dalbergia sissoo promotes fracture healing and its application in ovariectomy-induced osteoporotic rats.

Karvande A, Khedgikar V, Kushwaha P, Ahmad N, Kothari P, Verma A, Kumar P, Nagar GK, Mishra PR, Maurya R, Trivedi R.

J Pharm Pharmacol. 2017 Oct;69(10):1381-1397. doi: 10.1111/jphp.12764. Epub 2017 Jun 30.

PMID:
28664619
6.

Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss.

Gautam J, Khedgikar V, Kushwaha P, Choudhary D, Nagar GK, Dev K, Dixit P, Singh D, Maurya R, Trivedi R.

Br J Nutr. 2017 Mar;117(5):645-661. doi: 10.1017/S0007114517000149. Epub 2017 Apr 3.

PMID:
28367764
7.

BMP signaling is required for adult skeletal homeostasis and mediates bone anabolic action of parathyroid hormone.

Khan MP, Khan K, Yadav PS, Singh AK, Nag A, Prasahar P, Mittal M, China SP, Tewari MC, Nagar GK, Tewari D, Trivedi AK, Sanyal S, Bandyopadhyay A, Chattopadhyay N.

Bone. 2016 Nov;92:132-144. doi: 10.1016/j.bone.2016.08.018. Epub 2016 Aug 24.

PMID:
27567726
8.

Odanacatib Restores Trabecular Bone of Skeletally Mature Female Rabbits With Osteopenia but Induces Brittleness of Cortical Bone: A Comparative Study of the Investigational Drug With PTH, Estrogen, and Alendronate.

Khan MP, Singh AK, Singh AK, Shrivastava P, Tiwari MC, Nagar GK, Bora HK, Parameswaran V, Sanyal S, Bellare JR, Chattopadhyay N.

J Bone Miner Res. 2016 Mar;31(3):615-29. doi: 10.1002/jbmr.2719. Epub 2015 Oct 26. Erratum in: J Bone Miner Res. 2015 Oct;30(10):1944. J Bone Miner Res. 2018 Nov;33(11):2084-2085.

9.

Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia.

Khan MP, Singh AK, Joharapurkar AA, Yadav M, Shree S, Kumar H, Gurjar A, Mishra JS, Tiwari MC, Nagar GK, Kumar S, Ramachandran R, Sharan A, Jain MR, Trivedi AK, Maurya R, Godbole MM, Gayen JR, Sanyal S, Chattopadhyay N.

Diabetes. 2015 Jul;64(7):2609-23. doi: 10.2337/db14-1611. Epub 2015 Jan 29. Erratum in: Diabetes. 2017 Dec;66(12 ):3142-3143.

10.

Preventive effects of withaferin A isolated from the leaves of an Indian medicinal plant Withania somnifera (L.): comparisons with 17-β-estradiol and alendronate.

Khedgikar V, Ahmad N, Kushwaha P, Gautam J, Nagar GK, Singh D, Trivedi PK, Mishra PR, Sangwan NS, Trivedi R.

Nutrition. 2015 Jan;31(1):205-13. doi: 10.1016/j.nut.2014.05.010. Epub 2014 Jun 10.

PMID:
25466667
11.

Ovariectomized Rats with Established Osteopenia have Diminished Mesenchymal Stem Cells in the Bone Marrow and Impaired Homing, Osteoinduction and Bone Regeneration at the Fracture Site.

Tewari D, Khan MP, Sagar N, China SP, Singh AK, Kheruka SC, Barai S, Tewari MC, Nagar GK, Vishwakarma AL, Ogechukwu OE, Bellare JR, Gambhir S, Chattopadhyay N.

Stem Cell Rev Rep. 2015 Apr;11(2):309-21. doi: 10.1007/s12015-014-9573-5.

PMID:
25433862
12.

Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone.

Khedgikar V, Kushwaha P, Gautam J, Verma A, Changkija B, Kumar A, Sharma S, Nagar GK, Singh D, Trivedi PK, Sangwan NS, Mishra PR, Trivedi R.

Cell Death Dis. 2013 Aug 22;4:e778. doi: 10.1038/cddis.2013.294.

13.

Exposure to As, Cd and Pb-mixture impairs myelin and axon development in rat brain, optic nerve and retina.

Rai NK, Ashok A, Rai A, Tripathi S, Nagar GK, Mitra K, Bandyopadhyay S.

Toxicol Appl Pharmacol. 2013 Dec 1;273(2):242-58. doi: 10.1016/j.taap.2013.05.003. Epub 2013 May 14.

PMID:
23680456
14.

Developmental exposure to As, Cd, and Pb mixture diminishes skeletal growth and causes osteopenia at maturity via osteoblast and chondrocyte malfunctioning in female rats.

Abbas S, Khan K, Khan MP, Nagar GK, Tewari D, Maurya SK, Dubey J, Ansari NG, Bandyopadhyay S, Chattopadhyay N.

Toxicol Sci. 2013 Jul;134(1):207-20. doi: 10.1093/toxsci/kft093. Epub 2013 Apr 19.

PMID:
23604592
15.

Isoformononetin, a methoxydaidzein present in medicinal plants, reverses bone loss in osteopenic rats and exerts bone anabolic action by preventing osteoblast apoptosis.

Srivastava K, Tyagi AM, Khan K, Dixit M, Lahiri S, Kumar A, Changkija B, Khan MP, Nagar GK, Yadav DK, Maurya R, Singh SP, Jain GK, Wahajuddin, Trivedi R, Chattopadhyay N, Singh D.

Phytomedicine. 2013 Apr 15;20(6):470-80. doi: 10.1016/j.phymed.2012.12.021. Epub 2013 Feb 8.

PMID:
23395215
16.

Osteogenic efficacy enhancement of kaempferol through an engineered layer-by-layer matrix: a study in ovariectomized rats.

Gupta GK, Kumar A, Khedgikar V, Kushwaha P, Gautam J, Nagar GK, Gupta V, Verma A, Dwivedi AK, Misra A, Trivedi R, Mishra PR.

Nanomedicine (Lond). 2013 May;8(5):757-71. doi: 10.2217/nnm.12.171. Epub 2013 Jan 14.

PMID:
23311987
17.

EGb 761 promotes osteoblastogenesis, lowers bone marrow adipogenesis and atherosclerotic plaque formation.

Gautam J, Kushwaha P, Swarnkar G, Khedgikar V, Nagar GK, Singh D, Singh V, Jain M, Barthwal M, Trivedi R.

Phytomedicine. 2012 Sep 15;19(12):1134-42. doi: 10.1016/j.phymed.2012.07.005. Epub 2012 Aug 27.

PMID:
22951391
18.

Positive skeletal effects of cladrin, a naturally occurring dimethoxydaidzein, in osteopenic rats that were maintained after treatment discontinuation.

Khan K, Sharan K, Swarnkar G, Chakravarti B, Mittal M, Barbhuyan TK, China SP, Khan MP, Nagar GK, Yadav D, Dixit P, Maurya R, Chattopadhyay N.

Osteoporos Int. 2013 Apr;24(4):1455-70. doi: 10.1007/s00198-012-2121-8. Epub 2012 Aug 30.

PMID:
22932734
19.

In vivo efficacy studies of layer-by-layer nano-matrix bearing kaempferol for the conditions of osteoporosis: a study in ovariectomized rat model.

Kumar A, Gupta GK, Khedgikar V, Gautam J, Kushwaha P, Changkija B, Nagar GK, Gupta V, Verma A, Dwivedi AK, Chattopadhyay N, Mishra PR, Trivedi R.

Eur J Pharm Biopharm. 2012 Nov;82(3):508-17. doi: 10.1016/j.ejpb.2012.08.001. Epub 2012 Aug 24.

PMID:
22926146
20.

A standardized phytopreparation from an Indian medicinal plant (Dalbergia sissoo) has antiresorptive and bone-forming effects on a postmenopausal osteoporosis model of rat.

Khedgikar V, Gautam J, Kushwaha P, Kumar A, Nagar GK, Dixit P, Chillara R, Voruganti S, Singh SP, Uddin W, Jain GK, Singh D, Maurya R, Chattopadhyay N, Trivedi R.

Menopause. 2012 Dec;19(12):1336-46. doi: 10.1097/gme.0b013e318256b6ae.

PMID:
22850441
21.

Formononetin reverses established osteopenia in adult ovariectomized rats.

Tyagi AM, Srivastava K, Singh AK, Kumar A, Changkija B, Pandey R, Lahiri S, Nagar GK, Yadav DK, Maurya R, Trivedi R, Singh D.

Menopause. 2012 Aug;19(8):856-63. doi: 10.1097/gme.0b013e31824f9306.

PMID:
22781783
22.

Evaluation of Cameroonian plants towards experimental bone regeneration.

Ngueguim FT, Khan MP, Donfack JH, Siddiqui JA, Tewari D, Nagar GK, Tiwari SC, Theophile D, Maurya R, Chattopadhyay N.

J Ethnopharmacol. 2012 May 7;141(1):331-7. doi: 10.1016/j.jep.2012.02.041. Epub 2012 Mar 5.

PMID:
22414477
23.

Total extract and standardized fraction from the stem bark of Butea monosperma have osteoprotective action: evidence for the nonestrogenic osteogenic effect of the standardized fraction.

Pandey R, Gautam AK, Bhargavan B, Trivedi R, Swarnkar G, Nagar GK, Yadav DK, Kumar M, Rawat P, Manickavasagam L, Kumar A, Maurya R, Goel A, Jain GK, Chattopadhyay N, Singh D.

Menopause. 2010 May-Jun;17(3):602-10. doi: 10.1097/gme.0b013e3181d0f7f0.

PMID:
20395887
24.

A novel flavonoid, 6-C-beta-d-glucopyranosyl-(2S,3S)-(+)-3',4',5,7-tetrahydroxyflavanone, isolated from Ulmus wallichiana Planchon mitigates ovariectomy-induced osteoporosis in rats.

Sharan K, Swarnkar G, Siddiqui JA, Kumar A, Rawat P, Kumar M, Nagar GK, Manickavasagam L, Singh SP, Mishra G, Wahajuddin, Jain GK, Maurya R, Chattopadhyay N.

Menopause. 2010 May-Jun;17(3):577-86. doi: 10.1097/gme.0b013e3181d2ce7f.

PMID:
20393370
25.

Extract and fraction from Ulmus wallichiana Planchon promote peak bone achievement and have a nonestrogenic osteoprotective effect.

Sharan K, Siddiqui JA, Swarnkar G, Tyagi AM, Kumar A, Rawat P, Kumar M, Nagar GK, Arya KR, Manickavasagam L, Jain GK, Maurya R, Chattopadhyay N.

Menopause. 2010 Mar;17(2):393-402. doi: 10.1097/gme.0b013e3181bfae38.

PMID:
20009959
26.

Anti-apoptotic role of omega-3-fatty acids in developing brain: perinatal hypothyroid rat cerebellum as apoptotic model.

Sinha RA, Khare P, Rai A, Maurya SK, Pathak A, Mohan V, Nagar GK, Mudiam MK, Godbole MM, Bandyopadhyay S.

Int J Dev Neurosci. 2009 Jun;27(4):377-83. doi: 10.1016/j.ijdevneu.2009.02.003. Epub 2009 Mar 5.

PMID:
19460632
27.

Effects of Egb 761 on bone mineral density, bone microstructure, and osteoblast function: Possible roles of quercetin and kaempferol.

Trivedi R, Kumar A, Gupta V, Kumar S, Nagar GK, Romero JR, Dwivedi AK, Chattopadhyay N.

Mol Cell Endocrinol. 2009 Apr 10;302(1):86-91. doi: 10.1016/j.mce.2009.01.011. Epub 2009 Jan 22.

PMID:
19356626

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