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Items: 1 to 50 of 115

1.

Glutamic Acid Decarboxylase Autoantibody-negative Slowly Progressive Type 1 Diabetes Mellitus: A Case Report and Literature Review.

Kobayashi M, Ohara N, Ikeda Y, Nagano O, Takada T, Kodama M, Sone H.

Intern Med. 2018 Aug 10. doi: 10.2169/internalmedicine.1008-18. [Epub ahead of print]

2.

Gamma Knife Radiosurgery for Metastatic Brain Tumors from Malignant Melanomas: A Japanese Multi-Institutional Cooperative and Retrospective Cohort Study (JLGK1501).

Shuto T, Yamamoto M, Yomo S, Kondoh T, Kobayashi T, Sato M, Okamoto H, Serizawa T, Nagano O, Kenai H, Obara T, Iwai Y, Yasuda S, Hasegawa T, Kubo K, Shidoh S, Mori K, Hayashi M, Inoue A, Onoue S, Gondo M, Matsunaga S.

Stereotact Funct Neurosurg. 2018;96(3):162-171. doi: 10.1159/000489948. Epub 2018 Jul 3.

3.

Bias flow rate and ventilation efficiency during adult high-frequency oscillatory ventilation: a lung model study.

Nagano O, Yumoto T, Nishimatsu A, Kanazawa S, Fujita T, Asaba S, Yamanouchi H.

Intensive Care Med Exp. 2018 Apr 19;6(1):11. doi: 10.1186/s40635-018-0176-3.

4.

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.

Shiota M, Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, Suematsu M.

Nat Commun. 2018 Apr 19;9(1):1561. doi: 10.1038/s41467-018-03899-1.

5.

Development of a functional thyroid model based on an organoid culture system.

Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, Kameyama K, Tsuchihashi K, Sugihara E, Uchino S, Ito K, Kawakubo H, Takeuchi H, Kitagawa Y, Saya H, Nagano O.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):783-789. doi: 10.1016/j.bbrc.2018.02.154. Epub 2018 Feb 19.

PMID:
29470983
6.

CD44 variant-dependent regulation of redox balance in EGFR mutation-positive non-small cell lung cancer: A target for treatment.

Kawano Y, Iwama E, Tsuchihashi K, Shibahara D, Harada T, Tanaka K, Nagano O, Saya H, Nakanishi Y, Okamoto I.

Lung Cancer. 2017 Nov;113:72-78. doi: 10.1016/j.lungcan.2017.09.008. Epub 2017 Sep 14.

PMID:
29110853
7.

A Multi-institutional Prospective Observational Study of Stereotactic Radiosurgery for Patients With Multiple Brain Metastases (JLGK0901 Study Update): Irradiation-related Complications and Long-term Maintenance of Mini-Mental State Examination Scores.

Yamamoto M, Serizawa T, Higuchi Y, Sato Y, Kawagishi J, Yamanaka K, Shuto T, Akabane A, Jokura H, Yomo S, Nagano O, Aoyama H.

Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):31-40. doi: 10.1016/j.ijrobp.2017.04.037. Epub 2017 Aug 7.

PMID:
28816158
8.

Quantification of the radiation dose to the pyramidal tract using tractography in treatment planning for stereotactic radiosurgery.

Kawasaki K, Matsumoto M, Kase M, Nagano O, Aoyagi K, Kageyama T.

Radiol Phys Technol. 2017 Dec;10(4):507-514. doi: 10.1007/s12194-017-0411-8. Epub 2017 Aug 7.

PMID:
28785993
9.

Improving the Prognostic Value of Disease-Specific Graded Prognostic Assessment Model for Renal Cell Carcinoma by Incorporation of Cumulative Intracranial Tumor Volume.

Ali MA, Hirshman BR, Wilson B, Schupper AJ, Joshi R, Proudfoot JA, Goetsch SJ, Alksne JF, Ott K, Aiyama H, Nagano O, Carter BS, Chiang V, Serizawa T, Yamamoto M, Chen CC.

World Neurosurg. 2017 Dec;108:151-156. doi: 10.1016/j.wneu.2017.07.109. Epub 2017 Jul 25.

10.

Survival Patterns of 5750 Stereotactic Radiosurgery-Treated Patients with Brain Metastasis as a Function of the Number of Lesions.

Ali MA, Hirshman BR, Wilson B, Carroll KT, Proudfoot JA, Goetsch SJ, Alksne JF, Ott K, Aiyama H, Nagano O, Carter BS, Fogarty G, Hong A, Serizawa T, Yamamoto M, Chen CC.

World Neurosurg. 2017 Nov;107:944-951.e1. doi: 10.1016/j.wneu.2017.07.062. Epub 2017 Jul 19.

11.

Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non-small-cell lung cancer.

Otsubo K, Nosaki K, Imamura CK, Ogata H, Fujita A, Sakata S, Hirai F, Toyokawa G, Iwama E, Harada T, Seto T, Takenoyama M, Ozeki T, Mushiroda T, Inada M, Kishimoto J, Tsuchihashi K, Suina K, Nagano O, Saya H, Nakanishi Y, Okamoto I.

Cancer Sci. 2017 Sep;108(9):1843-1849. doi: 10.1111/cas.13309. Epub 2017 Jul 26.

12.

cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.

Miyano K, Cabral H, Miura Y, Matsumoto Y, Mochida Y, Kinoh H, Iwata C, Nagano O, Saya H, Nishiyama N, Kataoka K, Yamasoba T.

J Control Release. 2017 Sep 10;261:275-286. doi: 10.1016/j.jconrel.2017.06.021. Epub 2017 Jun 27.

PMID:
28666729
13.

Superior Prognostic Value of Cumulative Intracranial Tumor Volume Relative to Largest Intracranial Tumor Volume for Stereotactic Radiosurgery-Treated Brain Metastasis Patients.

Hirshman BR, Wilson B, Ali MA, Proudfoot JA, Koiso T, Nagano O, Carter BS, Serizawa T, Yamamoto M, Chen CC.

Neurosurgery. 2018 Apr 1;82(4):473-480. doi: 10.1093/neuros/nyx225.

14.

The impact of EpCAM expression on response to chemotherapy and clinical outcomes in patients with epithelial ovarian cancer.

Tayama S, Motohara T, Narantuya D, Li C, Fujimoto K, Sakaguchi I, Tashiro H, Saya H, Nagano O, Katabuchi H.

Oncotarget. 2017 Jul 4;8(27):44312-44325. doi: 10.18632/oncotarget.17871.

15.

Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.

Kasai S, Furuichi Y, Ando N, Kagami K, Abe M, Nakane T, Goi K, Inukai T, Saitoh S, Ohno S, Okazaki S, Nagano O, Saya H, Sugita K.

Cell Death Dis. 2017 Jun 1;8(6):e2857. doi: 10.1038/cddis.2017.249.

16.

Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407).

Shitara K, Doi T, Nagano O, Fukutani M, Hasegawa H, Nomura S, Sato A, Kuwata T, Asai K, Einaga Y, Tsuchihashi K, Suina K, Maeda Y, Saya H, Ohtsu A.

Gastric Cancer. 2017 Nov;20(6):1004-1009. doi: 10.1007/s10120-017-0720-y. Epub 2017 May 2.

PMID:
28466360
17.

Distinct metaplastic and inflammatory phenotypes in autoimmune and adenocarcinoma-associated chronic atrophic gastritis.

Jeong S, Choi E, Petersen CP, Roland JT, Federico A, Ippolito R, D'Armiento FP, Nardone G, Nagano O, Saya H, Romano M, Goldenring JR.

United European Gastroenterol J. 2017 Feb;5(1):37-44. doi: 10.1177/2050640616644142. Epub 2016 Jun 23.

18.

Robustness of the neurological prognostic score in brain metastasis patients treated with Gamma Knife radiosurgery.

Serizawa T, Higuchi Y, Nagano O, Matsuda S, Aoyagi K, Ono J, Saeki N, Iwadate Y, Hirai T, Takemoto S, Shibamoto Y.

J Neurosurg. 2017 Nov;127(5):1000-1006. doi: 10.3171/2016.8.JNS16528. Epub 2016 Dec 2.

PMID:
27911235
19.

Gamma Knife radiosurgery for brain metastases from pulmonary large cell neuroendocrine carcinoma: a Japanese multi-institutional cooperative study (JLGK1401).

Kawabe T, Yamamoto M, Sato Y, Yomo S, Kondoh T, Nagano O, Serizawa T, Tsugawa T, Okamoto H, Akabane A, Aita K, Sato M, Jokura H, Kawagishi J, Shuto T, Kawai H, Moriki A, Kenai H, Iwai Y, Gondo M, Hasegawa T, Yasuda S, Kikuchi Y, Nagatomo Y, Watanabe S, Hashimoto N.

J Neurosurg. 2016 Dec;125(Suppl 1):11-17.

PMID:
27903179
20.

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.

Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D.

PLoS One. 2016 Jun 2;11(6):e0156595. doi: 10.1371/journal.pone.0156595. eCollection 2016.

21.

Dose-escalation study for the targeting of CD44v+ cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205).

Shitara K, Doi T, Nagano O, Imamura CK, Ozeki T, Ishii Y, Tsuchihashi K, Takahashi S, Nakajima TE, Hironaka S, Fukutani M, Hasegawa H, Nomura S, Sato A, Einaga Y, Kuwata T, Saya H, Ohtsu A.

Gastric Cancer. 2017 Mar;20(2):341-349. doi: 10.1007/s10120-016-0610-8. Epub 2016 Apr 7.

PMID:
27055559
22.

Potential of sulfasalazine as a therapeutic sensitizer for CD44 splice variant 9-positive urogenital cancer.

Takayama T, Kubo T, Morikawa A, Morita T, Nagano O, Saya H.

Med Oncol. 2016 May;33(5):45. doi: 10.1007/s12032-016-0760-x. Epub 2016 Apr 4.

PMID:
27044355
23.

Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines.

Wang M, Miura Y, Tsuchihashi K, Miyano K, Nagano O, Yoshikawa M, Tanabe A, Makino J, Mochida Y, Nishiyama N, Saya H, Cabral H, Kataoka K.

J Control Release. 2016 May 28;230:26-33. doi: 10.1016/j.jconrel.2016.03.038. Epub 2016 Mar 31.

PMID:
27040816
24.

Treatment Results of Gamma Knife Radiosurgery for Central Neurocytoma: Report of a Japanese Multi-Institutional Cooperative Study.

Yamanaka K, Iwai Y, Shuto T, Kida Y, Sato M, Hayashi M, Kondo T, Hirai H, Hori R, Kubo K, Mori H, Nagano O, Serizawa T.

World Neurosurg. 2016 Jun;90:300-305. doi: 10.1016/j.wneu.2016.03.016. Epub 2016 Mar 14.

PMID:
26987638
25.

The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).

Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H, Nagano O.

Cancer Res. 2016 May 15;76(10):2954-63. doi: 10.1158/0008-5472.CAN-15-2121. Epub 2016 Mar 15.

26.

Gamma Knife surgery for patients with jugular foramen schwannomas: a multiinstitutional retrospective study in Japan.

Hasegawa T, Kato T, Kida Y, Sasaki A, Iwai Y, Kondoh T, Tsugawa T, Sato M, Sato M, Nagano O, Nakaya K, Nakazaki K, Kano T, Hasui K, Nagatomo Y, Yasuda S, Moriki A, Serizawa T, Osano S, Inoue A.

J Neurosurg. 2016 Oct;125(4):822-831. Epub 2016 Jan 22.

PMID:
26799304
27.

Development of an ErbB4 monoclonal antibody that blocks neuregulin-1-induced ErbB4 activation in cancer cells.

Okazaki S, Nakatani F, Masuko K, Tsuchihashi K, Ueda S, Masuko T, Saya H, Nagano O.

Biochem Biophys Res Commun. 2016 Jan 29;470(1):239-44. doi: 10.1016/j.bbrc.2016.01.045. Epub 2016 Jan 11.

28.

Sulfasalazine, a therapeutic agent for ulcerative colitis, inhibits the growth of CD44v9(+) cancer stem cells in ulcerative colitis-related cancer.

Seishima R, Okabayashi K, Nagano O, Hasegawa H, Tsuruta M, Shimoda M, Kameyama K, Saya H, Kitagawa Y.

Clin Res Hepatol Gastroenterol. 2016 Sep;40(4):487-93. doi: 10.1016/j.clinre.2015.11.007. Epub 2016 Jan 5.

PMID:
26775891
29.

Gamma Knife surgery for patients with facial nerve schwannomas: a multiinstitutional retrospective study in Japan.

Hasegawa T, Kato T, Kida Y, Hayashi M, Tsugawa T, Iwai Y, Sato M, Okamoto H, Kano T, Osano S, Nagano O, Nakazaki K.

J Neurosurg. 2016 Feb;124(2):403-10. doi: 10.3171/2015.3.JNS142677. Epub 2015 Sep 11.

PMID:
26361275
30.

Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma.

Hirono S, Iwadate Y, Higuchi Y, Serizawa T, Nagano O, Matsutani T, Saeki N.

J Neurooncol. 2015 Jun;123(2):237-44. doi: 10.1007/s11060-015-1786-1. Epub 2015 Apr 25.

PMID:
25911295
31.

Stereotactic radiosurgery for intracranial hemangioblastomas: a retrospective international outcome study.

Kano H, Shuto T, Iwai Y, Sheehan J, Yamamoto M, McBride HL, Sato M, Serizawa T, Yomo S, Moriki A, Kohda Y, Young B, Suzuki S, Kenai H, Duma C, Kikuchi Y, Mathieu D, Akabane A, Nagano O, Kondziolka D, Lunsford LD.

J Neurosurg. 2015 Jun;122(6):1469-78. doi: 10.3171/2014.10.JNS131602. Epub 2015 Mar 27.

PMID:
25816088
32.

Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis.

Seishima R, Wada T, Tsuchihashi K, Okazaki S, Yoshikawa M, Oshima H, Oshima M, Sato T, Hasegawa H, Kitagawa Y, Goldenring JR, Saya H, Nagano O.

Cancer Prev Res (Phila). 2015 Jun;8(6):492-501. doi: 10.1158/1940-6207.CAPR-15-0025-T. Epub 2015 Mar 26.

33.

Mean lung pressure during adult high-frequency oscillatory ventilation: an experimental study using a lung model.

Hirayama T, Nagano O, Shiba N, Yumoto T, Sato K, Terado M, Ugawa T, Ichiba S, Ujike Y.

Acta Med Okayama. 2014 Dec;68(6):323-9.

34.

A new grading system focusing on neurological outcomes for brain metastases treated with stereotactic radiosurgery: the modified Basic Score for Brain Metastases.

Serizawa T, Higuchi Y, Nagano O, Matsuda S, Ono J, Saeki N, Hirai T, Miyakawa A, Shibamoto Y.

J Neurosurg. 2014 Dec;121 Suppl:35-43. doi: 10.3171/2014.7.GKS14980.

PMID:
25434935
35.

Feasibility study of immediate pharyngeal cooling initiation in cardiac arrest patients after arrival at the emergency room.

Takeda Y, Kawashima T, Kiyota K, Oda S, Morimoto N, Kobata H, Isobe H, Honda M, Fujimi S, Onda J, I S, Sakamoto T, Ishikawa M, Nakano H, Sadamitsu D, Kishikawa M, Kinoshita K, Yokoyama T, Harada M, Kitaura M, Ichihara K, Hashimoto H, Tsuji H, Yorifuji T, Nagano O, Katayama H, Ujike Y, Morita K.

Resuscitation. 2014 Dec;85(12):1647-53. doi: 10.1016/j.resuscitation.2014.09.014. Epub 2014 Sep 28.

36.

Venous reddening as a possible sign of hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis for moyamoya disease: case report.

Machida T, Ono J, Nomura R, Fujikawa A, Nagano O, Higuchi Y.

Neurol Med Chir (Tokyo). 2014;54(10):827-31. Epub 2014 Mar 27.

37.

Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study.

Yamamoto M, Serizawa T, Shuto T, Akabane A, Higuchi Y, Kawagishi J, Yamanaka K, Sato Y, Jokura H, Yomo S, Nagano O, Kenai H, Moriki A, Suzuki S, Kida Y, Iwai Y, Hayashi M, Onishi H, Gondo M, Sato M, Akimitsu T, Kubo K, Kikuchi Y, Shibasaki T, Goto T, Takanashi M, Mori Y, Takakura K, Saeki N, Kunieda E, Aoyama H, Momoshima S, Tsuchiya K.

Lancet Oncol. 2014 Apr;15(4):387-95. doi: 10.1016/S1470-2045(14)70061-0. Epub 2014 Mar 10.

PMID:
24621620
38.

Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation.

Ishimoto T, Sugihara H, Watanabe M, Sawayama H, Iwatsuki M, Baba Y, Okabe H, Hidaka K, Yokoyama N, Miyake K, Yoshikawa M, Nagano O, Komohara Y, Takeya M, Saya H, Baba H.

Carcinogenesis. 2014 May;35(5):1003-11. doi: 10.1093/carcin/bgt402. Epub 2013 Dec 6.

PMID:
24318997
39.

CD44s signals the acquisition of the mesenchymal phenotype required for anchorage-independent cell survival in hepatocellular carcinoma.

Okabe H, Ishimoto T, Mima K, Nakagawa S, Hayashi H, Kuroki H, Imai K, Nitta H, Saito S, Hashimoto D, Chikamoto A, Ishiko T, Watanabe M, Nagano O, Beppu T, Saya H, Baba H.

Br J Cancer. 2014 Feb 18;110(4):958-66. doi: 10.1038/bjc.2013.759. Epub 2013 Dec 3.

40.

In vivo pH monitoring using boron doped diamond microelectrode and silver needles: application to stomach disorder diagnosis.

Fierro S, Seishima R, Nagano O, Saya H, Einaga Y.

Sci Rep. 2013 Nov 19;3:3257. doi: 10.1038/srep03257.

41.

Stereotactic radiosurgery for brain metastases.

Serizawa T, Higuchi Y, Nagano O.

Neurosurg Clin N Am. 2013 Oct;24(4):597-603. doi: 10.1016/j.nec.2013.05.007. Epub 2013 Jul 12. Review.

PMID:
24093577
42.

Phase II trial of gefitinib alone without radiation therapy for Japanese patients with brain metastases from EGFR-mutant lung adenocarcinoma.

Iuchi T, Shingyoji M, Sakaida T, Hatano K, Nagano O, Itakura M, Kageyama H, Yokoi S, Hasegawa Y, Kawasaki K, Iizasa T.

Lung Cancer. 2013 Nov;82(2):282-7. doi: 10.1016/j.lungcan.2013.08.016. Epub 2013 Aug 28.

PMID:
24021541
43.

Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia.

Wada T, Ishimoto T, Seishima R, Tsuchihashi K, Yoshikawa M, Oshima H, Oshima M, Masuko T, Wright NA, Furuhashi S, Hirashima K, Baba H, Kitagawa Y, Saya H, Nagano O.

Cancer Sci. 2013 Oct;104(10):1323-9. doi: 10.1111/cas.12236. Epub 2013 Aug 12.

44.

CD44 variant 9 expression in primary early gastric cancer as a predictive marker for recurrence.

Hirata K, Suzuki H, Imaeda H, Matsuzaki J, Tsugawa H, Nagano O, Asakura K, Saya H, Hibi T.

Br J Cancer. 2013 Jul 23;109(2):379-86. doi: 10.1038/bjc.2013.314. Epub 2013 Jun 18.

45.

Redox regulation in stem-like cancer cells by CD44 variant isoforms.

Nagano O, Okazaki S, Saya H.

Oncogene. 2013 Oct 31;32(44):5191-8. doi: 10.1038/onc.2012.638. Epub 2013 Jan 21. Review.

PMID:
23334333
46.

xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

Yoshikawa M, Tsuchihashi K, Ishimoto T, Yae T, Motohara T, Sugihara E, Onishi N, Masuko T, Yoshizawa K, Kawashiri S, Mukai M, Asoda S, Kawana H, Nakagawa T, Saya H, Nagano O.

Cancer Res. 2013 Mar 15;73(6):1855-66. doi: 10.1158/0008-5472.CAN-12-3609-T. Epub 2013 Jan 14.

47.

Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells.

Tsugawa H, Suzuki H, Saya H, Hatakeyama M, Hirayama T, Hirata K, Nagano O, Matsuzaki J, Hibi T.

Cell Host Microbe. 2012 Dec 13;12(6):764-77. doi: 10.1016/j.chom.2012.10.014.

48.

Validity of two recently-proposed prognostic grading indices for lung, gastro-intestinal, breast and renal cell cancer patients with radiosurgically-treated brain metastases.

Yamamoto M, Serizawa T, Sato Y, Kawabe T, Higuchi Y, Nagano O, Barfod BE, Ono J, Kasuya H, Urakawa Y.

J Neurooncol. 2013 Feb;111(3):327-35. doi: 10.1007/s11060-012-1019-9. Epub 2012 Dec 9.

PMID:
23224746
49.

Testing different brain metastasis grading systems in stereotactic radiosurgery: Radiation Therapy Oncology Group's RPA, SIR, BSBM, GPA, and modified RPA.

Serizawa T, Higuchi Y, Nagano O, Hirai T, Ono J, Saeki N, Miyakawa A.

J Neurosurg. 2012 Dec;117 Suppl:31-7. doi: 10.3171/2012.8.GKS12710.

PMID:
23205786
50.

Gene expression profile of a newly established choriocarcinoma cell line, iC3-1, compared to existing choriocarcinoma cell lines and normal placenta.

Kobayashi Y, Banno K, Shimizu T, Ueki A, Tsuji K, Masuda K, Kisu I, Nomura H, Tominaga E, Nagano O, Saya H, Aoki D.

Placenta. 2013 Feb;34(2):110-8. doi: 10.1016/j.placenta.2012.11.003. Epub 2012 Nov 28.

PMID:
23199791

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