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Items: 1 to 50 of 183

1.

Systematic expression analysis of genes related to generation of action potentials in human iPS cell-derived cardiomyocytes.

Kodama M, Furutani K, Kimura R, Ando T, Sakamoto K, Nagamori S, Ashihara T, Kurachi Y, Sekino Y, Furukawa T, Kanda Y, Kurokawa J.

J Pharmacol Sci. 2019 Jun 21. pii: S1347-8613(19)34171-4. doi: 10.1016/j.jphs.2019.06.006. [Epub ahead of print]

2.

[Cell surface pH imaging using poly(ethylene glycol)-phospholipid: its potential as the core structure of membrane anchored-probes].

Ohgaki R, Teramura Y, Hayashi D, Nagamori S, Takai M, Kanai Y.

Nihon Yakurigaku Zasshi. 2019;153(6):254-260. doi: 10.1254/fpj.153.254. Japanese.

PMID:
31178529
3.

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.

Lee Y, Wiriyasermkul P, Jin C, Quan L, Ohgaki R, Okuda S, Kusakizako T, Nishizawa T, Oda K, Ishitani R, Yokoyama T, Nakane T, Shirouzu M, Endou H, Nagamori S, Kanai Y, Nureki O.

Nat Struct Mol Biol. 2019 Jun;26(6):510-517. doi: 10.1038/s41594-019-0237-7. Epub 2019 Jun 3.

PMID:
31160781
4.

Axitinib-Induced Hypothyroidism as a Predictor of Long-Term Survival in Patients with Metastatic Renal Cell Carcinoma.

Takada S, Hashishita H, Nagamori S, Endo M.

Urol Int. 2019;102(4):435-440. doi: 10.1159/000499089. Epub 2019 Apr 10.

5.

Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization.

Iwamoto M, Saso W, Sugiyama R, Ishii K, Ohki M, Nagamori S, Suzuki R, Aizaki H, Ryo A, Yun JH, Park SY, Ohtani N, Muramatsu M, Iwami S, Tanaka Y, Sureau C, Wakita T, Watashi K.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8487-8492. doi: 10.1073/pnas.1811064116. Epub 2019 Apr 5.

PMID:
30952782
6.

Three-year follow-up of a phase II study of radium-223 dichloride in Japanese patients with symptomatic castration-resistant prostate cancer and bone metastases.

Uemura H, Uemura H, Nagamori S, Wakumoto Y, Kimura G, Kikukawa H, Yokomizo A, Mizokami A, Kosaka T, Masumori N, Kawasaki Y, Yonese J, Nasu Y, Fukasawa S, Sugiyama T, Kinuya S, Hosono M, Yamaguchi I, Akagawa T, Matsubara N.

Int J Clin Oncol. 2019 May;24(5):557-566. doi: 10.1007/s10147-018-01389-4. Epub 2019 Mar 14.

7.

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.

Miyabe J, Ohgaki R, Saito K, Wei L, Quan L, Jin C, Liu X, Okuda S, Nagamori S, Ohki H, Yoshino K, Inohara H, Kanai Y.

J Pharmacol Sci. 2019 Mar;139(3):215-222. doi: 10.1016/j.jphs.2019.01.012. Epub 2019 Feb 18.

8.

Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2.

Aoki M, Watabe T, Nagamori S, Naka S, Ikeda H, Kongpracha P, Horitsugi G, Kanai Y, Shimosegawa E, Kanai Y, Hatazawa J.

Ann Nucl Med. 2019 Jun;33(6):394-403. doi: 10.1007/s12149-019-01346-9. Epub 2019 Feb 28.

PMID:
30820863
9.

Comparative study of lymph node dissection, and oncological outcomes of laparoscopic and open radical nephroureterectomy for patients with urothelial carcinoma of the upper urinary tract undergoing regional lymph node dissection.

Abe T, Kondo T, Harabayashi T, Takada N, Matsumoto R, Osawa T, Minami K, Nagamori S, Maruyama S, Murai S, Tanabe K, Shinohara N.

Jpn J Clin Oncol. 2018 Nov 1;48(11):1001-1011. doi: 10.1093/jjco/hyy128.

10.

Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex.

Weng L, Han YP, Enomoto A, Kitaura Y, Nagamori S, Kanai Y, Asai N, An J, Takagishi M, Asai M, Mii S, Masuko T, Shimomura Y, Takahashi M.

PLoS Biol. 2018 Mar 14;16(3):e2005090. doi: 10.1371/journal.pbio.2005090. eCollection 2018 Mar.

11.

Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate.

Ohgaki R, Teramura Y, Hayashi D, Quan L, Okuda S, Nagamori S, Takai M, Kanai Y.

Sci Rep. 2017 Dec 13;7(1):17484. doi: 10.1038/s41598-017-17459-y.

12.

Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells.

Ikeda K, Kinoshita M, Kayama H, Nagamori S, Kongpracha P, Umemoto E, Okumura R, Kurakawa T, Murakami M, Mikami N, Shintani Y, Ueno S, Andou A, Ito M, Tsumura H, Yasutomo K, Ozono K, Takashima S, Sakaguchi S, Kanai Y, Takeda K.

Cell Rep. 2017 Nov 14;21(7):1824-1838. doi: 10.1016/j.celrep.2017.10.082.

13.

Isolation and characterization of racemase from Ensifer sp. 23-3 that acts on α-aminolactams and α-amino acid amides.

Matsui D, Fuhshuku KI, Nagamori S, Takata M, Asano Y.

J Ind Microbiol Biotechnol. 2017 Nov;44(11):1503-1510. doi: 10.1007/s10295-017-1981-5. Epub 2017 Sep 19.

PMID:
28929416
14.

The usefulness of testosterone administration in identifying false-positive elevation of serum human chorionic gonadotropin in patients with germ cell tumor.

Takizawa A, Kawai K, Kawahara T, Kojima T, Maruyama S, Shinohara N, Akamatsu S, Kamba T, Nakamura T, Ukimura O, Jikuya R, Kishida T, Kakimoto K, Nishimura K, Harabayashi T, Nagamori S, Yamashita S, Arai Y, Sawada Y, Sekido N, Kinoshita H, Matsuda T, Nakagawa T, Homma Y, Nishiyama H.

J Cancer Res Clin Oncol. 2018 Jan;144(1):109-115. doi: 10.1007/s00432-017-2520-5. Epub 2017 Sep 13.

PMID:
28905168
15.

Phase II study of radium-223 dichloride in Japanese patients with symptomatic castration-resistant prostate cancer.

Matsubara N, Nagamori S, Wakumoto Y, Uemura H, Kimura G, Yokomizo A, Kikukawa H, Mizokami A, Kosaka T, Masumori N, Kawasaki Y, Yonese J, Nasu Y, Fukasawa S, Sugiyama T, Kinuya S, Hosono M, Yamaguchi I, Tsutsui H, Uemura H.

Int J Clin Oncol. 2018 Feb;23(1):173-180. doi: 10.1007/s10147-017-1176-0. Epub 2017 Aug 2.

16.

Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease.

Shinozaki Y, Furuichi K, Toyama T, Kitajima S, Hara A, Iwata Y, Sakai N, Shimizu M, Kaneko S, Isozumi N, Nagamori S, Kanai Y, Sugiura T, Kato Y, Wada T.

Kidney Int. 2017 Dec;92(6):1356-1369. doi: 10.1016/j.kint.2017.04.032. Epub 2017 Jul 26.

PMID:
28754554
17.

Clinical Significance and Phenotype of MTA1 Expression in Esophageal Squamous Cell Carcinoma.

Honjo H, Toh Y, Sohda M, Suzuki S, Kaira K, Kanai Y, Nagamori S, Oyama T, Yokobori T, Miyazaki T, Kuwano H.

Anticancer Res. 2017 Aug;37(8):4147-4155.

PMID:
28739699
18.

Utilization of Liver Microsomes to Estimate Hepatic Intrinsic Clearance of Monoamine Oxidase Substrate Drugs in Humans.

Masuo Y, Nagamori S, Hasegawa A, Hayashi K, Isozumi N, Nakamichi N, Kanai Y, Kato Y.

Pharm Res. 2017 Jun;34(6):1233-1243. doi: 10.1007/s11095-017-2140-4. Epub 2017 Mar 30.

PMID:
28361200
19.

Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc.

Ohgaki R, Ohmori T, Hara S, Nakagomi S, Kanai-Azuma M, Kaneda-Nakashima K, Okuda S, Nagamori S, Kanai Y.

Mol Cell Biol. 2017 May 16;37(11). pii: e00427-16. doi: 10.1128/MCB.00427-16. Print 2017 Jun 1.

20.

Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1).

Kongpracha P, Nagamori S, Wiriyasermkul P, Tanaka Y, Kaneda K, Okuda S, Ohgaki R, Kanai Y.

J Pharmacol Sci. 2017 Feb;133(2):96-102. doi: 10.1016/j.jphs.2017.01.006. Epub 2017 Feb 9.

21.

Increased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue: IN VIVO METABOLIC TURNOVER ANALYSIS.

Nagao H, Nishizawa H, Bamba T, Nakayama Y, Isozumi N, Nagamori S, Kanai Y, Tanaka Y, Kita S, Fukuda S, Funahashi T, Maeda N, Fukusaki E, Shimomura I.

J Biol Chem. 2017 Mar 17;292(11):4469-4483. doi: 10.1074/jbc.M116.770172. Epub 2017 Jan 24.

22.

Expression of a human NPT1/SLC17A1 missense variant which increases urate export.

Sakiyama M, Matsuo H, Nagamori S, Ling W, Kawamura Y, Nakayama A, Higashino T, Chiba T, Ichida K, Kanai Y, Shinomiya N.

Nucleosides Nucleotides Nucleic Acids. 2016 Dec;35(10-12):536-542.

PMID:
27906618
23.

Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer.

Samson A, Bentham MJ, Scott K, Nuovo G, Bloy A, Appleton E, Adair RA, Dave R, Peckham-Cooper A, Toogood G, Nagamori S, Coffey M, Vile R, Harrington K, Selby P, Errington-Mais F, Melcher A, Griffin S.

Gut. 2018 Mar;67(3):562-573. doi: 10.1136/gutjnl-2016-312009. Epub 2016 Nov 15.

24.

Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma.

Ohshima Y, Kaira K, Yamaguchi A, Oriuchi N, Tominaga H, Nagamori S, Kanai Y, Yokobori T, Miyazaki T, Asao T, Tsushima Y, Kuwano H, Ishioka NS.

Cancer Sci. 2016 Oct;107(10):1499-1505. doi: 10.1111/cas.13021. Epub 2016 Oct 3.

25.

18F-FBPA as a tumor-specific probe of L-type amino acid transporter 1 (LAT1): a comparison study with 18F-FDG and 11C-Methionine PET.

Watabe T, Ikeda H, Nagamori S, Wiriyasermkul P, Tanaka Y, Naka S, Kanai Y, Hagiwara K, Aoki M, Shimosegawa E, Kanai Y, Hatazawa J.

Eur J Nucl Med Mol Imaging. 2017 Feb;44(2):321-331. doi: 10.1007/s00259-016-3487-1. Epub 2016 Aug 22.

PMID:
27550420
26.

[Advancement of surgical treatment in prostate cancer].

Harabayashi T, Takada N, Minami K, Nagamori S.

Nihon Rinsho. 2016 May 20;74 Suppl 3:416-20. Japanese. No abstract available.

PMID:
27344767
27.

Core-fucosylation plays a pivotal role in hepatitis B pseudo virus infection: a possible implication for HBV glycotherapy.

Takamatsu S, Shimomura M, Kamada Y, Maeda H, Sobajima T, Hikita H, Iijima M, Okamoto Y, Misaki R, Fujiyama K, Nagamori S, Kanai Y, Takehara T, Ueda K, Kuroda S, Miyoshi E.

Glycobiology. 2016 Nov;26(11):1180-1189. doi: 10.1093/glycob/cww067. Epub 2016 Jun 21.

PMID:
27329181
28.

Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 inhibitor Canagliflozin with SGLT1 and SGLT2.

Ohgaki R, Wei L, Yamada K, Hara T, Kuriyama C, Okuda S, Ueta K, Shiotani M, Nagamori S, Kanai Y.

J Pharmacol Exp Ther. 2016 Jul;358(1):94-102. doi: 10.1124/jpet.116.232025. Epub 2016 Apr 27.

PMID:
27189972
29.

[Comparison of the Four-Week and Three-Week Regimens of GC Therapy for Urothelial Cancer].

Takada S, Tamaki S, Nagamori S, Endou M.

Gan To Kagaku Ryoho. 2016 Feb;43(2):219-22. Japanese.

PMID:
27067686
30.

Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma.

Honjo H, Kaira K, Miyazaki T, Yokobori T, Kanai Y, Nagamori S, Oyama T, Asao T, Kuwano H.

J Surg Oncol. 2016 Mar;113(4):381-9. doi: 10.1002/jso.24160. Epub 2016 Mar 3.

PMID:
26936531
31.

Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography.

Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Kato Y, Oriuchi N, Nagamori S, Kanai Y.

J Pharmacol Sci. 2016 Feb;130(2):101-9. doi: 10.1016/j.jphs.2016.01.001. Epub 2016 Jan 21.

32.

Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging.

Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Oriuchi N, Nagamori S, Kanai Y.

Cancer Sci. 2016 Mar;107(3):347-52. doi: 10.1111/cas.12878. Epub 2016 Feb 19.

33.

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.

Nagamori S, Wiriyasermkul P, Guarch ME, Okuyama H, Nakagomi S, Tadagaki K, Nishinaka Y, Bodoy S, Takafuji K, Okuda S, Kurokawa J, Ohgaki R, Nunes V, Palacín M, Kanai Y.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):775-80. doi: 10.1073/pnas.1519959113. Epub 2016 Jan 6.

34.

Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.

Nagamori S, Wiriyasermkul P, Okuda S, Kojima N, Hari Y, Kiyonaka S, Mori Y, Tominaga H, Ohgaki R, Kanai Y.

Amino Acids. 2016 Apr;48(4):1045-58. doi: 10.1007/s00726-015-2158-z. Epub 2016 Jan 2.

PMID:
26724922
35.

Voided urine cytology and low-grade urothelial neoplasia of the bladder: factors that influence the sensitivity.

Yamashiro K, Taira K, Nakajima M, Azuma M, Koseki M, Abe T, Suzuki H, Minami K, Harabayashi T, Nagamori S.

J Am Soc Cytopathol. 2016 Jul - Aug;5(4):227-234. doi: 10.1016/j.jasc.2016.02.004. Epub 2016 Mar 3.

PMID:
31042513
36.

Factors Prognostic for Survival in Japanese Patients Treated with Sunitinib as First-line Therapy for Metastatic Clear Cell Renal Cell Cancer.

Kawai Y, Osawa T, Kobayashi K, Inoue R, Yamamoto Y, Matsumoto H, Nagao K, Hara T, Sakano S, Nagamori S, Matsuyama H.

Asian Pac J Cancer Prev. 2015;16(14):5687-90.

37.

Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors.

Kaira K, Nakamura K, Hirakawa T, Imai H, Tominaga H, Oriuchi N, Nagamori S, Kanai Y, Tsukamoto N, Oyama T, Asao T, Minegishi T.

Am J Transl Res. 2015 Jun 15;7(6):1161-71. eCollection 2015.

38.

Clinical significance of coexpression of L-type amino acid transporter 1 (LAT1) and ASC amino acid transporter 2 (ASCT2) in lung adenocarcinoma.

Yazawa T, Shimizu K, Kaira K, Nagashima T, Ohtaki Y, Atsumi J, Obayashi K, Nagamori S, Kanai Y, Oyama T, Takeyoshi I.

Am J Transl Res. 2015 Jun 15;7(6):1126-39. eCollection 2015.

39.

Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in cutaneous melanoma.

Shimizu A, Kaira K, Kato M, Yasuda M, Takahashi A, Tominaga H, Oriuchi N, Nagamori S, Kanai Y, Oyama T, Asao T, Ishikawa O.

Melanoma Res. 2015 Oct;25(5):399-405. doi: 10.1097/CMR.0000000000000181.

PMID:
26237765
40.

L-type amino acid transporter-1 and CD98 expression in bone and soft tissue tumors.

Koshi H, Sano T, Handa T, Yanagawa T, Saitou K, Nagamori S, Kanai Y, Takagishi K, Oyama T.

Pathol Int. 2015 Sep;65(9):460-7. doi: 10.1111/pin.12323. Epub 2015 Jul 1.

PMID:
26134029
41.

Prospective mapping of lymph node metastasis in Japanese patients undergoing radical cystectomy for bladder cancer: characteristics of micrometastasis.

Matsumoto R, Takada N, Abe T, Minami K, Harabayashi T, Nagamori S, Hatanaka KC, Miyajima N, Tsuchiya K, Maruyama S, Murai S, Shinohara N.

Jpn J Clin Oncol. 2015 Sep;45(9):874-80. doi: 10.1093/jjco/hyv091. Epub 2015 Jun 24.

PMID:
26109677
42.

Molecular architecture of the stria vascularis membrane transport system, which is essential for physiological functions of the mammalian cochlea.

Uetsuka S, Ogata G, Nagamori S, Isozumi N, Nin F, Yoshida T, Komune S, Kitahara T, Kikkawa Y, Inohara H, Kanai Y, Hibino H.

Eur J Neurosci. 2015 Aug;42(3):1984-2002. doi: 10.1111/ejn.12973. Epub 2015 Jul 16.

PMID:
26060893
43.

Expression of Amino Acid Transporters (LAT1 and ASCT2) in Patients with Stage III/IV Laryngeal Squamous Cell Carcinoma.

Nikkuni O, Kaira K, Toyoda M, Shino M, Sakakura K, Takahashi K, Tominaga H, Oriuchi N, Suzuki M, Iijima M, Asao T, Nishiyama M, Nagamori S, Kanai Y, Oyama T, Chikamatsu K.

Pathol Oncol Res. 2015 Sep;21(4):1175-81. doi: 10.1007/s12253-015-9954-3. Epub 2015 May 30.

PMID:
26024742
44.

[Risk factors for predicting severe leukopenia induced by docetaxel plus prednisolone in patients with Castration-Resistant Prostate cancer].

Takada S, Tamaki S, Nagamori S, Endou M.

Gan To Kagaku Ryoho. 2015 May;42(5):591-4. Japanese.

PMID:
25981653
45.

Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer.

Kaira K, Arakawa K, Shimizu K, Oriuchi N, Nagamori S, Kanai Y, Oyama T, Takeyoshi I.

Am J Transl Res. 2015 Feb 15;7(2):356-63. eCollection 2015.

46.

Development of a Widely Usable Amino Acid Tracer: ⁷⁶Br-α-Methyl-Phenylalanine for Tumor PET Imaging.

Hanaoka H, Ohshima Y, Suzuki Y, Yamaguchi A, Watanabe S, Uehara T, Nagamori S, Kanai Y, Ishioka NS, Tsushima Y, Endo K, Arano Y.

J Nucl Med. 2015 May;56(5):791-7. doi: 10.2967/jnumed.114.152215. Epub 2015 Mar 26.

47.

Differential Expression of Sonic Hedgehog Protein in Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.

Al-Bahrani R, Nagamori S, Leng R, Petryk A, Sergi C.

Pathol Oncol Res. 2015 Sep;21(4):901-8. doi: 10.1007/s12253-015-9918-7. Epub 2015 Mar 5.

PMID:
25740074
48.

Differential SIRT1 expression in hepatocellular carcinomas and cholangiocarcinoma of the liver.

Al-Bahrani R, Tuertcher D, Zailaie S, Abuetabh Y, Nagamori S, Zetouni N, Bahitham W, Sergi C.

Ann Clin Lab Sci. 2015 Winter;45(1):3-9. Erratum in: Ann Clin Lab Sci. 2015 Fall;45(6):720.

PMID:
25696003
49.

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2.

Wongthai P, Hagiwara K, Miyoshi Y, Wiriyasermkul P, Wei L, Ohgaki R, Kato I, Hamase K, Nagamori S, Kanai Y.

Cancer Sci. 2015 Mar;106(3):279-86. doi: 10.1111/cas.12602. Epub 2015 Mar 6.

50.

Expression of amino acid transporters (LAT1, ASCT2 and xCT) as clinical significance in hepatocellular carcinoma.

Namikawa M, Kakizaki S, Kaira K, Tojima H, Yamazaki Y, Horiguchi N, Sato K, Oriuchi N, Tominaga H, Sunose Y, Nagamori S, Kanai Y, Oyama T, Takeyoshi I, Yamada M.

Hepatol Res. 2015 Sep;45(9):1014-1022. doi: 10.1111/hepr.12431. Epub 2014 Dec 11.

PMID:
25297701

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