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Items: 33

1.

Species differences in the developmental toxicity of procymidone-Placental transfer of procymidone in pregnant rats, rabbits, and monkeys.

Tarui H, Tomigahara Y, Nagahori H, Sugimoto K, Mogi M, Kawamura S, Isobe N, Kaneko H.

J Pestic Sci. 2018 May 20;43(2):79-87. doi: 10.1584/jpestics.D17-079.

2.

Flumioxazin metabolism in pregnant animals and cell-based protoporphyrinogen IX oxidase (PPO) inhibition assay of fetal metabolites in various animal species to elucidate the mechanism of the rat-specific developmental toxicity.

Abe J, Isobe N, Mikata K, Nagahori H, Naito Y, Saji H, Ono M, Kawamura S.

Toxicol Appl Pharmacol. 2018 Jan 15;339:34-41. doi: 10.1016/j.taap.2017.11.028. Epub 2017 Dec 2.

PMID:
29198728
3.

Metabolism of metofluthrin in rats: II. Excretion, distribution and amount of metabolites.

Abe J, Tomigahara Y, Tarui H, Nagahori H, Kurosawa M, Sugimoto K, Isobe N.

Xenobiotica. 2018 Nov;48(11):1113-1127. doi: 10.1080/00498254.2017.1397813. Epub 2017 Nov 20.

PMID:
29157071
4.

Editor's Highlight: Development of Novel Neural Embryonic Stem CellTests for High-Throughput Screening of Embryotoxic Chemicals.

Kobayashi K, Suzuki N, Higashi K, Muroi A, Le Coz F, Nagahori H, Saito K.

Toxicol Sci. 2017 Sep 1;159(1):238-250. doi: 10.1093/toxsci/kfx130.

PMID:
28903496
5.

Combining Genomics To Identify the Pathways of Post-Transcriptional Nongenotoxic Signaling and Energy Homeostasis in Livers of Rats Treated with the Pregnane X Receptor Agonist, Pregnenolone Carbonitrile.

Nagahori H, Nakamura K, Sumida K, Ito S, Ohtsuki S.

J Proteome Res. 2017 Oct 6;16(10):3634-3645. doi: 10.1021/acs.jproteome.7b00364. Epub 2017 Sep 6.

PMID:
28825834
6.

Editor's Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes.

Okuda Y, Kushida M, Sumida K, Nagahori H, Nakamura Y, Higuchi H, Kawamura S, Lake BG, Cohen SM, Yamada T.

Toxicol Sci. 2017 Aug 1;158(2):412-430. doi: 10.1093/toxsci/kfx102.

PMID:
28520973
7.

Metabolism of metofluthrin in rats: I. Identification of metabolites.

Abe J, Nagahori H, Tarui H, Tomigahara Y, Isobe N.

Xenobiotica. 2018 Feb;48(2):157-169. doi: 10.1080/00498254.2017.1283718. Epub 2017 Feb 5.

PMID:
28092216
8.

Prediction of in vivo developmental toxicity by combination of Hand1-Luc embryonic stem cell test and metabolic stability test with clarification of metabolically inapplicable candidates.

Nagahori H, Suzuki N, Le Coz F, Omori T, Saito K.

Toxicol Lett. 2016 Sep 30;259:44-51. doi: 10.1016/j.toxlet.2016.07.022. Epub 2016 Jul 18.

PMID:
27444379
9.

Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19.

Shirotani N, Togawa M, Ikushiro S, Sakaki T, Harada T, Miyagawa H, Matsui M, Nagahori H, Mikata K, Nishioka K, Hirai N, Akamatsu M.

Bioorg Med Chem. 2015 Oct 15;23(20):6594-601. doi: 10.1016/j.bmc.2015.09.019. Epub 2015 Sep 11.

PMID:
26404412
10.

Metabolism of (Z)-(1R,3R)-Profluthrin in Rats.

Abe J, Nagahori H, Omori R, Mikata K, Kurosawa M, Tomigahara Y, Isobe N.

J Agric Food Chem. 2015 Oct 7;63(39):8651-61. doi: 10.1021/acs.jafc.5b03321. Epub 2015 Sep 24.

PMID:
26357989
11.

Quantitative structure-activity relationship model for the fetal-maternal blood concentration ratio of chemicals in humans.

Takaku T, Nagahori H, Sogame Y, Takagi T.

Biol Pharm Bull. 2015;38(6):930-4. doi: 10.1248/bpb.b14-00883.

13.

Human hepatocytes support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogen sodium phenobarbital in an in vivo study using a chimeric mouse with humanized liver.

Yamada T, Okuda Y, Kushida M, Sumida K, Takeuchi H, Nagahori H, Fukuda T, Lake BG, Cohen SM, Kawamura S.

Toxicol Sci. 2014 Nov;142(1):137-57. doi: 10.1093/toxsci/kfu173. Epub 2014 Aug 21.

PMID:
25145657
14.

Metabolism and physiologically based pharmacokinetic modeling of flumioxazin in pregnant animals.

Takaku T, Nagahori H, Sogame Y.

Toxicol Appl Pharmacol. 2014 Jun 15;277(3):242-9. doi: 10.1016/j.taap.2014.03.022. Epub 2014 Apr 6.

PMID:
24717917
15.

Metabolism of propyrisulfuron: 14C excretion, 14C concentration in plasma and tissues, and amount of metabolites in rats.

Takaku T, Mikata K, Nagahori H, Sogame Y.

Xenobiotica. 2014 Oct;44(10):882-92. doi: 10.3109/00498254.2014.903009. Epub 2014 Mar 24.

PMID:
24661045
16.

Identification of metabolites of propyrisulfuron in rats.

Takaku T, Mikata K, Nagahori H, Sogame Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Apr 1;955-956:64-71. doi: 10.1016/j.jchromb.2014.02.021. Epub 2014 Feb 22.

PMID:
24631812
18.

Metabolism of pyridalyl in rats: excretion, distribution, and biotransformation of dichloropropenyl-labeled pyridalyl.

Nagahori H, Tomigahara Y, Isobe N, Kaneko H.

J Agric Food Chem. 2009 Nov 25;57(22):10845-51. doi: 10.1021/jf9026469.

PMID:
19919122
19.

Metabolism of pyridalyl in rats.

Nagahori H, Saito K, Tomigahara Y, Isobe N, Kaneko H.

Drug Metab Dispos. 2009 Dec;37(12):2284-9. doi: 10.1124/dmd.109.028878. Epub 2009 Sep 22.

20.

Metabolism of flufenpyr-ethyl in rats and mice.

Nagahori H, Matsunaga H, Tomigahara Y, Isobe N, Kaneko H.

J Agric Food Chem. 2009 Jun 10;57(11):4872-7. doi: 10.1021/jf9011592.

PMID:
19397263
21.

Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes.

Hirose Y, Nagahori H, Yamada T, Deguchi Y, Tomigahara Y, Nishioka K, Uwagawa S, Kawamura S, Isobe N, Lake BG, Okuno Y.

Toxicology. 2009 Apr 5;258(1):64-9.

PMID:
19378387
22.

Mode of action analysis for the synthetic pyrethroid metofluthrin-induced rat liver tumors: evidence for hepatic CYP2B induction and hepatocyte proliferation.

Deguchi Y, Yamada T, Hirose Y, Nagahori H, Kushida M, Sumida K, Sukata T, Tomigahara Y, Nishioka K, Uwagawa S, Kawamura S, Okuno Y.

Toxicol Sci. 2009 Mar;108(1):69-80. doi: 10.1093/toxsci/kfp006. Epub 2009 Jan 27.

PMID:
19176366
23.

Free residual chlorine in bathing water reduces the water-holding capacity of the stratum corneum in atopic skin.

Seki T, Morimatsu S, Nagahori H, Morohashi M.

J Dermatol. 2003 Mar;30(3):196-202.

PMID:
12692355
24.
25.

An in vitro reporter gene assay method incorporating metabolic activation with human and rat S9 or liver microsomes.

Sumida K, Ooe N, Nagahori H, Saito K, Isobe N, Kaneko H, Nakatsuka I.

Biochem Biophys Res Commun. 2001 Jan 12;280(1):85-91.

PMID:
11162482
26.

Metabolism of furametpyr. 2. (14)C excretion, (14)C concentrations in tissues, and amounts of metabolites in rats.

Nagahori H, Yoshino H, Tomigahara Y, Isobe N, Kaneko H, Nakatsuka I.

J Agric Food Chem. 2000 Nov;48(11):5760-7.

PMID:
11087551
27.

Metabolism of furametpyr. 1. Identification of metabolites and in vitro biotransformation in rats and humans.

Nagahori H, Yoshino H, Tomigahara Y, Isobe N, Kaneko H, Nakatsuka I.

J Agric Food Chem. 2000 Nov;48(11):5754-9.

PMID:
11087550
28.

An ultrastructural and immunohistochemical study of pigmented dermatofibrosarcoma protuberans (Bednar tumor).

Kagoura M, Toyoda M, Nagahori H, Makino T, Morohashi M.

Eur J Dermatol. 1999 Jul-Aug;9(5):366-9.

PMID:
10417439
29.

Syntheses and biological activities of renin inhibitors containing statine analogues.

Nishi T, Saito F, Nagahori H, Kataoka M, Morisawa Y, Yabe Y, Sakurai M, Higashida S, Shoji M, Matsushita Y, et al.

Chem Pharm Bull (Tokyo). 1990 Jan;38(1):103-9.

PMID:
2110866
30.

Studies on anticoccidial agents. 13. Synthesis and anticoccidial activity of nitropyridine-2- and -3-sulfonamides and derivatives.

Morisawa Y, Kataoka M, Nagahori H, Sakamoto T, Kitano N, Kusano K, Sato K.

J Med Chem. 1980 Dec;23(12):1376-80.

PMID:
7452692
31.

Studies on anticoccidial agents. 12. Synthesis and anticoccidial activity of methyl-2(6)-nitro- and -3(5)-nitropyridinecarboxamides.

Morisawa Y, Kataoka M, Sakamoto T, Nagahori H, Kitano N, Kusano K.

J Med Chem. 1978 Feb;21(2):194-9.

PMID:
621714
32.

Constituents from seeds of Alpinia galanga Wild, and their anti-ulcer activities.

Mitsui S, Kobayashi S, Nagahori H, Ogiso A.

Chem Pharm Bull (Tokyo). 1976 Oct;24(10):2377-82. No abstract available.

PMID:
1017082
33.

Chettaphanin-I, a novel furanoditerpenoid.

Sato A, Kurabayashi M, Nagahori H, Ogiso A, Mishima H.

Tetrahedron Lett. 1970 Mar;(13):1095-8. No abstract available.

PMID:
5439240

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