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Time to Cast the Prejudices Towards Transplantation of Kidneys Donated After Cardiac Death?

Van Loon E, Heylen L, Naesens M.

EClinicalMedicine. 2018 Oct 18;4-5:4-5. doi: 10.1016/j.eclinm.2018.10.003. eCollection 2018 Oct-Nov. No abstract available.


Specificity, strength and evolution of pretransplant donor-specific HLA antibodies determine outcome after kidney transplantation.

Senev A, Lerut E, Sandt VV, Coemans M, Callemeyn J, Sprangers B, Kuypers D, Emonds MP, Naesens M.

Am J Transplant. 2019 May 6. doi: 10.1111/ajt.15414. [Epub ahead of print]


Delayed bleeding of the Transplant Duodenum After Simultaneous Kidney Pancreas Transplantation: Case Series.

Van Mellaert A, Gillard P, Jochmans I, Demedts I, Sagaert X, Naesens M, Monbaliu D, Kuypers D, Pirenne J, Sprangers B.

Transplantation. 2019 Apr 1. doi: 10.1097/TP.0000000000002718. [Epub ahead of print]


Bone mineral density, bone turnover markers, and incident fractures in de novo kidney transplant recipients.

Evenepoel P, Claes K, Meijers B, Laurent MR, Bammens B, Naesens M, Sprangers B, Pottel H, Cavalier E, Kuypers D.

Kidney Int. 2019 Jun;95(6):1461-1470. doi: 10.1016/j.kint.2018.12.024. Epub 2019 Mar 4.


A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation.

Cippà PE, Liu J, Sun B, Kumar S, Naesens M, McMahon AP.

Nat Commun. 2019 Mar 11;10(1):1157. doi: 10.1038/s41467-019-09092-2.


Single nucleotide polymorphisms in renal transplantation: Can't see the wood for the trees.

Van Loon E, Naesens M.

Transplantation. 2019 Feb 7. doi: 10.1097/TP.0000000000002661. [Epub ahead of print] No abstract available.


Occurrence of Diabetic Nephropathy After Renal Transplantation Despite Intensive Glycemic Control: An Observational Cohort Study.

Coemans M, Van Loon E, Lerut E, Gillard P, Sprangers B, Senev A, Emonds MP, Van Keer J, Callemeyn J, Daniëls L, Sichien J, Verbeke G, Kuypers D, Mathieu C, Naesens M.

Diabetes Care. 2019 Apr;42(4):625-634. doi: 10.2337/dc18-1936. Epub 2019 Feb 14.


Histological picture of ABMR without HLA-DSA: Temporal dynamics of effector mechanisms are relevant in disease reclassification.

Senev A, Callemeyn J, Lerut E, Emonds MP, Naesens M.

Am J Transplant. 2019 Mar;19(3):954-955. doi: 10.1111/ajt.15234. Epub 2019 Jan 24. No abstract available.


Transcriptional trajectories of human kidney injury progression.

Cippà PE, Sun B, Liu J, Chen L, Naesens M, McMahon AP.

JCI Insight. 2018 Nov 15;3(22). pii: 123151. doi: 10.1172/jci.insight.123151.


Poor Vitamin K Status Is Associated With Low Bone Mineral Density and Increased Fracture Risk in End-Stage Renal Disease.

Evenepoel P, Claes K, Meijers B, Laurent M, Bammens B, Naesens M, Sprangers B, Pottel H, Cavalier E, Kuypers D.

J Bone Miner Res. 2019 Feb;34(2):262-269. doi: 10.1002/jbmr.3608. Epub 2018 Nov 14.


Natural killer cell infiltration is discriminative for antibody-mediated rejection and predicts outcome after kidney transplantation.

Yazdani S, Callemeyn J, Gazut S, Lerut E, de Loor H, Wevers M, Heylen L, Saison C, Koenig A, Thaunat O, Thorrez L, Kuypers D, Sprangers B, Noël LH, Van Lommel L, Schuit F, Essig M, Gwinner W, Anglicheau D, Marquet P, Naesens M.

Kidney Int. 2019 Jan;95(1):188-198. doi: 10.1016/j.kint.2018.08.027. Epub 2018 Nov 3.


Natural history of mineral metabolism, bone turnover and bone mineral density in de novo renal transplant recipients treated with a steroid minimization immunosuppressive protocol.

Evenepoel P, Claes K, Meijers B, Laurent MR, Bammens B, Naesens M, Sprangers B, Cavalier E, Kuypers D.

Nephrol Dial Transplant. 2018 Oct 17. doi: 10.1093/ndt/gfy306. [Epub ahead of print]


Do We Need Noninvasive Biomarkers for Delayed Graft Function After Kidney Transplantation?

Van Loon E, Naesens M.

Transplantation. 2019 May;103(5):870-872. doi: 10.1097/TP.0000000000002473. No abstract available.


Unraveling the Cause of Anuria Post Kidney Transplantation by Renal Scintigraphy.

Van Keerberghen CA, Naesens M, Gheysens O, Jochmans I, Pirenne J, Goffin K.

Clin Nucl Med. 2018 Dec;43(12):e458-e459. doi: 10.1097/RLU.0000000000002286.


Indications, risks and impact of failed allograft nephrectomy.

Ghyselen L, Naesens M.

Transplant Rev (Orlando). 2019 Jan;33(1):48-54. doi: 10.1016/j.trre.2018.08.001. Epub 2018 Sep 6. Review.


The special relativity of noninvasive biomarkers for acute rejection.

Naesens M.

Am J Transplant. 2019 Jan;19(1):5-8. doi: 10.1111/ajt.15078. Epub 2018 Sep 17. No abstract available.


Histological picture of antibody-mediated rejection without donor-specific anti-HLA antibodies: Clinical presentation and implications for outcome.

Senev A, Coemans M, Lerut E, Van Sandt V, Daniëls L, Kuypers D, Sprangers B, Emonds MP, Naesens M.

Am J Transplant. 2019 Mar;19(3):763-780. doi: 10.1111/ajt.15074. Epub 2018 Sep 28.


Analyses of the short- and long-term graft survival after kidney transplantation in Europe between 1986 and 2015.

Coemans M, Süsal C, Döhler B, Anglicheau D, Giral M, Bestard O, Legendre C, Emonds MP, Kuypers D, Molenberghs G, Verbeke G, Naesens M.

Kidney Int. 2018 Nov;94(5):964-973. doi: 10.1016/j.kint.2018.05.018. Epub 2018 Jul 24.


Banff survey on antibody-mediated rejection clinical practices in kidney transplantation: Diagnostic misinterpretation has potential therapeutic implications.

Schinstock CA, Sapir-Pichhadze R, Naesens M, Batal I, Bagnasco S, Bow L, Campbell P, Clahsen-van Groningen MC, Cooper M, Cozzi E, Dadhania D, Diekmann F, Budde K, Lower F, Orandi BJ, Rowshani AT, Cornell L, Kraus E.

Am J Transplant. 2019 Jan;19(1):123-131. doi: 10.1111/ajt.14979. Epub 2018 Jul 19.


The clinical significance of epitope mismatch load in kidney transplantation: A multicentre study.

Daniëls L, Naesens M, Bosmans JL, Abramowicz D, Nagler E, Van Laecke S, Peeters P, Kuypers D, Emonds MP.

Transpl Immunol. 2018 Oct;50:55-59. doi: 10.1016/j.trim.2018.06.006. Epub 2018 Jun 15.


The 1-year Renal Biopsy Index: a scoring system to drive biopsy indication at 1-year post-kidney transplantation.

Giral M, Renaudin K, Naesens M, Luning R, Anglicheau D, Morelon E, Huneau A, Paul C, Brouard S, Couvrat-Desvergnes G, Foucher Y, Dantan E.

Transpl Int. 2018 Jun 12. doi: 10.1111/tri.13290. [Epub ahead of print] Review.


Reply to Hernandez et al. - GWAS of acute renal graft rejection.

Massart A, Ghisdal L, Viklicky O, Naesens M, Abramowicz D, Abramowicz M.

Am J Transplant. 2018 Aug;18(8):2098-2099. doi: 10.1111/ajt.14877. Epub 2018 May 12. No abstract available.


Ischemia-Induced DNA Hypermethylation during Kidney Transplant Predicts Chronic Allograft Injury.

Heylen L, Thienpont B, Naesens M, Busschaert P, Depreeuw J, Smeets D, Jochmans I, Monbaliu D, Pirenne J, Lerut E, Ghesquiere B, Kuypers D, Lambrechts D, Sprangers B.

J Am Soc Nephrol. 2018 May;29(5):1566-1576. doi: 10.1681/ASN.2017091027. Epub 2018 Apr 2.


Inflammatory macrophage-associated 3-gene signature predicts subclinical allograft injury and graft survival.

Azad TD, Donato M, Heylen L, Liu AB, Shen-Orr SS, Sweeney TE, Maltzman JS, Naesens M, Khatri P.

JCI Insight. 2018 Jan 25;3(2). pii: 95659. doi: 10.1172/jci.insight.95659. eCollection 2018 Jan 25.


The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell-mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials.

Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, van Huyen JPD, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M.

Am J Transplant. 2018 Feb;18(2):293-307. doi: 10.1111/ajt.14625. Epub 2018 Jan 21.


Precision Transplant Medicine: Biomarkers to the Rescue.

Naesens M, Anglicheau D.

J Am Soc Nephrol. 2018 Jan;29(1):24-34. doi: 10.1681/ASN.2017010004. Epub 2017 Oct 9.


The duration of asystolic ischemia determines the risk of graft failure after circulatory-dead donor kidney transplantation: A Eurotransplant cohort study.

Heylen L, Jochmans I, Samuel U, Tieken I, Naesens M, Pirenne J, Sprangers B.

Am J Transplant. 2018 Apr;18(4):881-889. doi: 10.1111/ajt.14526. Epub 2017 Nov 10.


The time dependency of renal allograft histology.

Van Loon E, Lerut E, Naesens M.

Transpl Int. 2017 Nov;30(11):1081-1091. doi: 10.1111/tri.13042. Epub 2017 Sep 28. Review.


Tubulointerstitial expression and urinary excretion of connective tissue growth factor 3 months after renal transplantation predict interstitial fibrosis and tubular atrophy at 5 years in a retrospective cohort analysis.

Vanhove T, Kinashi H, Nguyen TQ, Metalidis C, Poesen K, Naesens M, Lerut E, Goldschmeding R, Kuypers DRJ.

Transpl Int. 2017 Jul;30(7):695-705. doi: 10.1111/tri.12960. Epub 2017 May 9.


Foretelling Graft Outcome by Molecular Evaluation of Renal Allograft Biopsies: The GoCAR Study.

Yazdani S, Naesens M.

Transplantation. 2017 Jan;101(1):5-7. doi: 10.1097/TP.0000000000001512. No abstract available.


Rethinking peritubular capillary basement membrane multilayering in renal transplant pathology: a case report.

Lopategui DM, Lerut E, Naesens M, Van Damme-Lombaerts R, Levtchenko E, Knops N.

Pediatr Nephrol. 2017 Apr;32(4):697-701. doi: 10.1007/s00467-016-3541-z. Epub 2016 Nov 17.


Mineral metabolism disturbances in kidney donors: smoke, no fire (yet).

Evenepoel P, Naesens M.

Kidney Int. 2016 Oct;90(4):734-6. doi: 10.1016/j.kint.2016.07.001.


The Impact of Anastomosis Time During Kidney Transplantation on Graft Loss: A Eurotransplant Cohort Study.

Heylen L, Pirenne J, Samuel U, Tieken I, Naesens M, Sprangers B, Jochmans I.

Am J Transplant. 2017 Mar;17(3):724-732. doi: 10.1111/ajt.14031. Epub 2016 Oct 4.


Establishing Biomarkers in Transplant Medicine: A Critical Review of Current Approaches.

Anglicheau D, Naesens M, Essig M, Gwinner W, Marquet P.

Transplantation. 2016 Oct;100(10):2024-38. doi: 10.1097/TP.0000000000001321. Review.


Decreased Circulating Sclerostin Levels in Renal Transplant Recipients With Persistent Hyperparathyroidism.

Evenepoel P, Claes K, Viaene L, Bammens B, Meijers B, Naesens M, Sprangers B, Kuypers D.

Transplantation. 2016 Oct;100(10):2188-93. doi: 10.1097/TP.0000000000001311.


Belatacept and Long-Term Outcomes in Kidney Transplantation.

Naesens M, Lerut E.

N Engl J Med. 2016 Jun 30;374(26):2598-9. doi: 10.1056/NEJMc1602859. No abstract available.


Calcineurin Inhibitor Nephrotoxicity in the Era of Antibody-Mediated Rejection.

Naesens M, Lerut E.

Transplantation. 2016 Aug;100(8):1599-600. doi: 10.1097/TP.0000000000001244. No abstract available.


Genome-Wide Association Study of Acute Renal Graft Rejection.

Ghisdal L, Baron C, Lebranchu Y, Viklický O, Konarikova A, Naesens M, Kuypers D, Dinic M, Alamartine E, Touchard G, Antoine T, Essig M, Rerolle JP, Merville P, Taupin JL, Le Meur Y, Grall-Jezequel A, Glowacki F, Noël C, Legendre C, Anglicheau D, Broeders N, Coppieters W, Docampo E, Georges M, Ajarchouh Z, Massart A, Racapé J, Abramowicz D, Abramowicz M.

Am J Transplant. 2017 Jan;17(1):201-209. doi: 10.1111/ajt.13912. Epub 2016 Jul 22.


Lymphocyte-depleting induction and steroid minimization after kidney transplantation: A review.

Naesens M, Berger S, Biancone L, Crespo M, Djamali A, Hertig A, Öllinger R, Portolés J, Zuckermann A, Pascual J.

Nefrologia. 2016 Sep - Oct;36(5):469-480. doi: 10.1016/j.nefro.2016.03.019. Epub 2016 May 14. Review. English, Spanish.


Intragraft Antiviral-Specific Gene Expression as a Distinctive Transcriptional Signature for Studies in Polyomavirus-Associated Nephropathy.

Sigdel TK, Bestard O, Salomonis N, Hsieh SC, Torras J, Naesens M, Tran TQ, Roedder S, Sarwal MM.

Transplantation. 2016 Oct;100(10):2062-70. doi: 10.1097/TP.0000000000001214.


Transplantation: BENEFIT of belatacept: kidney transplantation moves forward.

Naesens M, Thaunat O.

Nat Rev Nephrol. 2016 May;12(5):261-2. doi: 10.1038/nrneph.2016.34. Epub 2016 Mar 30. No abstract available.


The influence of renal transplantation on retained microbial-human co-metabolites.

Poesen R, Evenepoel P, de Loor H, Bammens B, Claes K, Sprangers B, Naesens M, Kuypers D, Augustijns P, Meijers B.

Nephrol Dial Transplant. 2016 Oct;31(10):1721-1729. Epub 2016 Mar 8.


Rabbit antithymocyte globulin and donor-specific antibodies in kidney transplantation--A review.

Pascual J, Zuckermann A, Djamali A, Hertig A, Naesens M.

Transplant Rev (Orlando). 2016 Apr;30(2):85-91. doi: 10.1016/j.trre.2015.12.002. Epub 2016 Feb 18. Review.


Phosphorus metabolism in peritoneal dialysis- and haemodialysis-treated patients.

Evenepoel P, Meijers BK, Bammens B, Viaene L, Claes K, Sprangers B, Naesens M, Hoekstra T, Schlieper G, Vanderschueren D, Kuypers D.

Nephrol Dial Transplant. 2016 Sep;31(9):1508-14. doi: 10.1093/ndt/gfv414. Epub 2016 Jan 31.


The Emerging Role of DNA Methylation in Kidney Transplantation: A Perspective.

Heylen L, Thienpont B, Naesens M, Lambrechts D, Sprangers B.

Am J Transplant. 2016 Apr;16(4):1070-8. doi: 10.1111/ajt.13585. Epub 2016 Jan 18. Review.


The DESCARTES-Nantes survey of kidney transplant recipients displaying clinical operational tolerance identifies 35 new tolerant patients and 34 almost tolerant patients.

Massart A, Pallier A, Pascual J, Viklicky O, Budde K, Spasovski G, Klinger M, Sever MS, Sørensen SS, Hadaya K, Oberbauer R, Dudley C, De Fijter JW, Yussim A, Hazzan M, Wekerle T, Berglund D, De Biase C, Pérez-Sáez MJ, Mühlfeld A, Orlando G, Clemente K, Lai Q, Pisani F, Kandus A, Baas M, Bemelman F, Ponikvar JB, Mazouz H, Stratta P, Subra JF, Villemain F, Hoitsma A, Braun L, Cantarell MC, Colak H, Courtney A, Frasca GM, Howse M, Naesens M, Reischig T, Serón D, Seyahi N, Tugmen C, Alonso Hernandez A, Beňa L, Biancone L, Cuna V, Díaz-Corte C, Dufay A, Gaasbeek A, Garnier A, Gatault P, Gentil Govantes MA, Glowacki F, Gross O, Hurault de Ligny B, Huynh-Do U, Janbon B, Jiménez Del Cerro LA, Keller F, La Manna G, Lauzurica R, Le Monies De Sagazan H, Thaiss F, Legendre C, Martin S, Moal MC, Noël C, Pillebout E, Piredda GB, Puga AR, Sulowicz W, Tuglular S, Prokopova M, Chesneau M, Le Moine A, Guérif P, Soulillou JP, Abramowicz M, Giral M, Racapé J, Maggiore U, Brouard S, Abramowicz D.

Nephrol Dial Transplant. 2016 Jun;31(6):1002-13. doi: 10.1093/ndt/gfv437. Epub 2016 Jan 12.


Zero-Time Renal Transplant Biopsies: A Comprehensive Review.

Naesens M.

Transplantation. 2016 Jul;100(7):1425-39. doi: 10.1097/TP.0000000000001018. Review.


Telomere length, cardiovascular risk and arteriosclerosis in human kidneys: an observational cohort study.

De Vusser K, Pieters N, Janssen B, Lerut E, Kuypers D, Jochmans I, Monbaliu D, Pirenne J, Nawrot T, Naesens M.

Aging (Albany NY). 2015 Oct;7(10):766-75.


The effect of anastomosis time on outcome in recipients of kidneys donated after brain death: a cohort study.

Heylen L, Naesens M, Jochmans I, Monbaliu D, Lerut E, Claes K, Heye S, Verhamme P, Coosemans W, Bammens B, Evenepoel P, Meijers B, Kuypers D, Sprangers B, Pirenne J.

Am J Transplant. 2015 Nov;15(11):2900-7. doi: 10.1111/ajt.13397.


RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection.

Van Aelst LN, Summer G, Li S, Gupta SK, Heggermont W, De Vusser K, Carai P, Naesens M, Van Cleemput J, Van de Werf F, Vanhaecke J, Thum T, Waer M, Papageorgiou AP, Schroen B, Heymans S.

Am J Transplant. 2016 Jan;16(1):99-110. doi: 10.1111/ajt.13421. Epub 2015 Aug 6.

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