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Improved oxygenation following methylprednisolone therapy and survival in paediatric acute respiratory distress syndrome.

Mitting RB, Ray S, Raffles M, Egan H, Goley P, Peters M, Nadel S.

PLoS One. 2019 Nov 26;14(11):e0225737. doi: 10.1371/journal.pone.0225737. eCollection 2019.


OMIP-062: A 14-Color, 16-Antibody Panel for Immunophenotyping Human Innate Lymphoid, Myeloid and T Cells in Small Volumes of Whole Blood and Pediatric Airway Samples.

Swieboda D, Guo Y, Sagawe S, Thwaites RS, Nadel S, Openshaw PJM, Culley FJ.

Cytometry A. 2019 Oct 21. doi: 10.1002/cyto.a.23907. [Epub ahead of print] No abstract available.


A Rare Mutation in SPLUNC1 Affects Bacterial Adherence and Invasion in Meningococcal Disease.

Mashbat B, Bellos E, Hodeib S, Bidmos F, Thwaites RS, Lu Y, Wright VJ, Herberg JA, Klobassa DS, Zenz W, Hansel TT, Nadel S, Langford PR, Schlapbach LJ, Li MS, Redinbo MR, Di YP, Levin M, Sancho-Shimizu V; European Union Childhood Life-Threatening Infectious Disease Study (EUCLIDS) Consortium.

Clin Infect Dis. 2019 Jul 1. pii: ciz600. doi: 10.1093/cid/ciz600. [Epub ahead of print]


Translational gap in pediatric septic shock management: an ESPNIC perspective.

Morin L, Kneyber M, Jansen NJG, Peters MJ, Javouhey E, Nadel S, Maclaren G, Schlapbach LJ, Tissieres P; ESPNIC Refractory Septic Shock Definition taskforce and the Infection, Systemic Inflammation and Sepsis ESPNIC section.

Ann Intensive Care. 2019 Jun 28;9(1):73. doi: 10.1186/s13613-019-0545-4.


Effects of saline or albumin fluid bolus in resuscitation: evidence from re-analysis of the FEAST trial.

Levin M, Cunnington AJ, Wilson C, Nadel S, Lang HJ, Ninis N, McCulloch M, Argent A, Buys H, Moxon CA, Best A, Nijman RG, Hoggart CJ.

Lancet Respir Med. 2019 Jul;7(7):581-593. doi: 10.1016/S2213-2600(19)30114-6. Epub 2019 Jun 10.


Ultrasound-Guided Botulinum Toxin Injections into the Salivary Glands for the Treatment of Drooling.

Abboud WA, Nadel S, Hassin-Baer S, Arad A, Dobriyan A, Yahalom R.

Isr Med Assoc J. 2019 Feb;21(2):116-119.


Feasibility and Acceptability of Methods to Collect Follow-Up Information From Parents 12 Months After Their Child's Emergency Admission to Pediatric Intensive Care.

Pulham RA, Wray J, Feinstein Y, Brown K, Pierce C, Nadel S, Pathan N, Garralda E, Ramnarayan P.

Pediatr Crit Care Med. 2019 Apr;20(4):e199-e207. doi: 10.1097/PCC.0000000000001892.


Invasive Meningococcal Disease in the Vaccine Era.

Nadel S, Ninis N.

Front Pediatr. 2018 Nov 9;6:321. doi: 10.3389/fped.2018.00321. eCollection 2018. Review.


Cohort profile of the Biomarkers of Acute Serious Illness in Children (BASIC) study: a prospective multicentre cohort study in critically ill children.

Feinstein Y, Walker JC, Peters MJ, Nadel S, Pathan N, Edmonds N, Herberg J, Kaforou M, Wright V, Levin M, Ramnarayan P.

BMJ Open. 2018 Nov 8;8(11):e024729. doi: 10.1136/bmjopen-2018-024729.


Overview of prevention and management of acute bronchiolitis due to respiratory syncytial virus.

Ghazaly M, Nadel S.

Expert Rev Anti Infect Ther. 2018 Dec;16(12):913-928. doi: 10.1080/14787210.2018.1543589. Epub 2018 Nov 9. Review.


Inflammation and psychopathology in children following PICU admission: an exploratory study.

Caspani G, Corbet Burcher G, Garralda ME, Cooper M, Pierce CM, Als LC, Nadel S.

Evid Based Ment Health. 2018 Nov;21(4):139-144. doi: 10.1136/ebmental-2018-300027. Epub 2018 Oct 9.


Restricted fluid bolus versus current practice in children with septic shock: the FiSh feasibility study and pilot RCT.

Inwald D, Canter RR, Woolfall K, O'Hara CB, Mouncey PR, Zenasni Z, Hudson N, Saunders S, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM.

Health Technol Assess. 2018 Sep;22(51):1-106. doi: 10.3310/hta22510.


Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.

Inwald DP, Canter R, Woolfall K, Mouncey P, Zenasni Z, O'Hara C, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM; PERUKI (Paediatric Emergency Research in the UK and Ireland) and PICS SG (Paediatric Intensive Care Society Study Group).

Arch Dis Child. 2019 May;104(5):426-431. doi: 10.1136/archdischild-2018-314924. Epub 2018 Aug 7.


Cross-Reactive Bactericidal Antimeningococcal Antibodies Can Be Isolated From Convalescing Invasive Meningococcal Disease Patients Using Reverse Vaccinology 2.0.

Bidmos FA, Nadel S, Screaton GR, Kroll JS, Langford PR.

Front Immunol. 2018 Jul 16;9:1621. doi: 10.3389/fimmu.2018.01621. eCollection 2018.


Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS).

Boeddha NP, Schlapbach LJ, Driessen GJ, Herberg JA, Rivero-Calle I, Cebey-López M, Klobassa DS, Philipsen R, de Groot R, Inwald DP, Nadel S, Paulus S, Pinnock E, Secka F, Anderson ST, Agbeko RS, Berger C, Fink CG, Carrol ED, Zenz W, Levin M, van der Flier M, Martinón-Torres F, Hazelzet JA, Emonts M; EUCLIDS consortium.

Crit Care. 2018 May 31;22(1):143. doi: 10.1186/s13054-018-2052-7.


Reduced Nasal Viral Load and IFN Responses in Infants with Respiratory Syncytial Virus Bronchiolitis and Respiratory Failure.

Thwaites RS, Coates M, Ito K, Ghazaly M, Feather C, Abdulla F, Tunstall T, Jain P, Cass L, Rapeport G, Hansel TT, Nadel S, Openshaw P.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1074-1084. doi: 10.1164/rccm.201712-2567OC.


Characteristics of children admitted to intensive care with acute bronchiolitis.

Ghazaly M, Nadel S.

Eur J Pediatr. 2018 Jun;177(6):913-920. doi: 10.1007/s00431-018-3138-6. Epub 2018 Apr 13.


Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples.

Thwaites RS, Jarvis HC, Singh N, Jha A, Pritchard A, Fan H, Tunstall T, Nanan J, Nadel S, Kon OM, Openshaw PJ, Hansel TT.

J Vis Exp. 2018 Jan 21;(131). doi: 10.3791/56413.


Management of suspected paediatric meningitis: a multicentre prospective cohort study.

Ramasamy R, Willis L, Kadambari S, Kelly DF, Heath PT, Nadel S, Pollard AJ, Sadarangani M.

Arch Dis Child. 2018 Dec;103(12):1114-1118. doi: 10.1136/archdischild-2017-313913. Epub 2018 Feb 7.


Assessing the Different Oncologic Disease Distribution and Postoperative Complications of Octogenarian and Nonagenarian Head and Neck Oncology Patients.

Sagiv D, Nadel S, Talmi YP, Yahalom R, Wolf M, Alon EE.

J Oral Maxillofac Surg. 2018 Jun;76(6):1355-1360. doi: 10.1016/j.joms.2017.11.037. Epub 2017 Dec 7.


Post-traumatic stress after PICU and corticosteroid use.

Corbet Burcher G, Picouto MD, Als LC, Cooper M, Pierce CM, Nadel S, Garralda ME.

Arch Dis Child. 2018 Sep;103(9):887-889. doi: 10.1136/archdischild-2017-314157. Epub 2017 Nov 25.


A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock.

O'Hara CB, Canter RR, Mouncey PR, Carter A, Jones N, Nadel S, Peters MJ, Lyttle MD, Harrison DA, Rowan KM, Inwald D, Woolfall K.

Arch Dis Child. 2018 Jan;103(1):28-32. doi: 10.1136/archdischild-2016-312515. Epub 2017 Aug 28.


Erratum to: Risk of over-diagnosis of hypotension in children: a comparative analysis of over 50,000 blood pressure measurements.

Ray S, Rogers L, Noren DP, Dhar R, Nadel S, Peters MJ, Inwald DP.

Intensive Care Med. 2017 Dec;43(12):1939. doi: 10.1007/s00134-017-4861-6. No abstract available.


Risk of over-diagnosis of hypotension in children: a comparative analysis of over 50,000 blood pressure measurements.

Ray S, Rogers L, Noren DP, Dhar R, Nadel S, Peters MJ, Inwald DP.

Intensive Care Med. 2017 Oct;43(10):1540-1541. doi: 10.1007/s00134-017-4843-8. Epub 2017 May 19. No abstract available. Erratum in: Intensive Care Med. 2017 Jun 6;:.


Shock due to faecal impaction.

Baik JS, Seers T, Qureshi S, Nadel S.

Arch Dis Child. 2018 Feb;103(2):127. doi: 10.1136/archdischild-2017-312672. Epub 2017 May 4. No abstract available.


Arthroscopy of the Temporomandibular Joint for the Treatment of Chronic Closed Lock.

Abboud W, Nadel S, Yarom N, Yahalom R.

Isr Med Assoc J. 2016 Jul;18(7):397-400.


Nasosorption as a Minimally Invasive Sampling Procedure: Mucosal Viral Load and Inflammation in Primary RSV Bronchiolitis.

Thwaites RS, Ito K, Chingono JMS, Coates M, Jarvis HC, Tunstall T, Anderson-Dring L, Cass L, Rapeport G, Openshaw PJ, Nadel S, Hansel TT.

J Infect Dis. 2017 Apr 15;215(8):1240-1244. doi: 10.1093/infdis/jix150.


A picture paints a thousand words.

Nadel S.

Acta Paediatr. 2017 Apr;106(4):532-533. doi: 10.1111/apa.13733. No abstract available.


Stress hormones and posttraumatic stress symptoms following paediatric critical illness: an exploratory study.

Als LC, Picouto MD, O'Donnell KJ, Nadel S, Cooper M, Pierce CM, Kramer T, Glover VAS, Garralda ME.

Eur Child Adolesc Psychiatry. 2017 May;26(5):511-519. doi: 10.1007/s00787-016-0933-3. Epub 2016 Dec 19. Review.


The Impact of Chronic Health Conditions on Length of Stay and Mortality in a General PICU.

O'Brien S, Nadel S, Almossawi O, Inwald DP.

Pediatr Crit Care Med. 2017 Jan;18(1):1-7. doi: 10.1097/PCC.0000000000000976.


Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies.

Martinón-Torres F, Png E, Khor CC, Davila S, Wright VJ, Sim KS, Vega A, Fachal L, Inwald D, Nadel S, Carrol ED, Martinón-Torres N, Alonso SM, Carracedo A, Morteruel E, López-Bayón J, Torre AC, Monge CC, de Aguilar PA, Torné EE, Martínez-Padilla MD, Martinón-Sánchez JM, Levin M, Hibberd ML, Salas A; ESIGEM network; ESPID meningococcal consortium – UK; EUCLIDS consortium members - Imperial College London (

Sci Rep. 2016 Nov 2;6:35842. doi: 10.1038/srep35842.


When water is thicker than blood: recognising a systemic cause of haemoptysis.

Wedge E, Abrahamson E, Tudor-Williams G, Nadel S, Deal J.

Arch Dis Child Educ Pract Ed. 2017 Aug;102(4):210-219. doi: 10.1136/archdischild-2015-308957. Epub 2016 Oct 25.


Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition.

Morin L, Ray S, Wilson C, Remy S, Benissa MR, Jansen NJG, Javouhey E, Peters MJ, Kneyber M, De Luca D, Nadel S, Schlapbach LJ, Maclaren G, Tissieres P; ESPNIC Refractory Septic Shock Definition Taskforce the Infection Systemic Inflammation Sepsis section of ESPNIC .

Intensive Care Med. 2016 Dec;42(12):1948-1957. doi: 10.1007/s00134-016-4574-2. Epub 2016 Oct 5.


Treatment of Meningococcal Disease.

Nadel S.

J Adolesc Health. 2016 Aug;59(2 Suppl):S21-8. doi: 10.1016/j.jadohealth.2016.04.013. Review.


Corrigendum to "The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent Adults" [J Infect 72 (2016) 405-438].

McGill F, Heyderman RS, Michael BD, Defres S, Beeching NJ, Borrow R, Glennie L, Gaillemin O, Wyncoll D, Kaczmarski E, Nadel S, Thwaites G, Cohen J, Davies NWS, Miller A, Rhodes A, Read R, Solomon T.

J Infect. 2016 Jun;72(6):768-769. doi: 10.1016/j.jinf.2016.04.001. Epub 2016 Apr 12. No abstract available.


What's New in Paediatric Sepsis.

Farrell D, Nadel S.

Curr Pediatr Rep. 2016;4:1-5. Epub 2016 Feb 20. Review.


The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults.

McGill F, Heyderman RS, Michael BD, Defres S, Beeching NJ, Borrow R, Glennie L, Gaillemin O, Wyncoll D, Kaczmarski E, Nadel S, Thwaites G, Cohen J, Davies NW, Miller A, Rhodes A, Read RC, Solomon T.

J Infect. 2016 Apr;72(4):405-38. doi: 10.1016/j.jinf.2016.01.007. Epub 2016 Feb 2. Erratum in: J Infect. 2016 Jun;72 (6):768-769.


Brain death determination: the imperative for policy and legal initiatives in Sub-Saharan Africa.

Waweru-Siika W, Clement ME, Lukoko L, Nadel S, Rosoff PM, Naanyu V, Kussin PS.

Glob Public Health. 2017 May;12(5):589-600. doi: 10.1080/17441692.2015.1094108. Epub 2015 Nov 13.


[Facial femalization in transgenders].

Yahalom R, Blinder D, Nadel S.

Refuat Hapeh Vehashinayim (1993). 2015 Jul;32(3):52-4, 70. Hebrew.


Treatment of Parental Post-Traumatic Stress Disorder After PICU Admission: Who, What, Where, When?

Nadel S, Als LC, Garralda ME.

Pediatr Crit Care Med. 2015 Nov;16(9):877-8. doi: 10.1097/PCC.0000000000000502. No abstract available.


The authors reply.

Inwald DP, Sinitsky L, Walls D, Nadel S.

Pediatr Crit Care Med. 2015 Sep;16(7):685-6. doi: 10.1097/PCC.0000000000000500. No abstract available.


Persistence of Neuropsychological Deficits Following Pediatric Critical Illness.

Als LC, Tennant A, Nadel S, Cooper M, Pierce CM, Garralda ME.

Crit Care Med. 2015 Aug;43(8):e312-5. doi: 10.1097/CCM.0000000000001075.


Mental and physical well-being following admission to pediatric intensive care.

Als LC, Picouto MD, Hau SM, Nadel S, Cooper M, Pierce CM, Kramer T, Garralda ME.

Pediatr Crit Care Med. 2015 Jun;16(5):e141-9. doi: 10.1097/PCC.0000000000000424.


Vaccine evaluation: lessons from a meningococcal B vaccine.

Sarfatti A, Martinón-Torres F, Nadel S.

Arch Dis Child. 2015 Jun;100(6):514-6. doi: 10.1136/archdischild-2014-306030. Epub 2015 Feb 10. No abstract available.


Fluid overload at 48 hours is associated with respiratory morbidity but not mortality in a general PICU: retrospective cohort study.

Sinitsky L, Walls D, Nadel S, Inwald DP.

Pediatr Crit Care Med. 2015 Mar;16(3):205-9. doi: 10.1097/PCC.0000000000000318.


Childhood meningitis in the conjugate vaccine era: a prospective cohort study.

Sadarangani M, Willis L, Kadambari S, Gormley S, Young Z, Beckley R, Gantlett K, Orf K, Blakey S, Martin NG, Kelly DF, Heath PT, Nadel S, Pollard AJ.

Arch Dis Child. 2015 Mar;100(3):292-4. doi: 10.1136/archdischild-2014-306813. Epub 2014 Sep 25.


Big babies and big adults surprise us by their outcomes: why?

Argent AC, Nadel S.

Intensive Care Med. 2014 Nov;40(11):1772-4. doi: 10.1007/s00134-014-3439-9. Epub 2014 Sep 3. No abstract available.


Think Hickam's dictum not Occam's razor in paediatric HIV.

Goodyear-Smith F, Sharland M, Nadel S.

BMJ Case Rep. 2014 Mar 18;2014. pii: bcr2013202029. doi: 10.1136/bcr-2013-202029.


Political Lancet.

Nadel S.

Lancet. 2013 Dec 14;382(9909):1980. doi: 10.1016/S0140-6736(13)62655-0. No abstract available.


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