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Items: 1 to 50 of 168


Enhancing Data Reliability in TOMAHAQ for Large-Scale Protein Quantification.

Liu F, Singhal K, Matney R, Acharya S, Akdis CA, Nadeau KC, Chien AS, Leib RD.

Proteomics. 2020 Feb 7:e1900105. doi: 10.1002/pmic.201900105. [Epub ahead of print]


Th2A and Th17 cell frequencies and regulatory markers as follow-up biomarker candidates for successful multifood oral immunotherapy.

Luce S, Chinthrajah S, Lyu SC, Nadeau KC, Mascarell L.

Allergy. 2020 Jan 12. doi: 10.1111/all.14180. [Epub ahead of print] No abstract available.


Summary of the Keystone Symposium "Origins of allergic disease: Microbial, epithelial and immune interactions," March 24-27, Tahoe City, California.

DeKruyff RH, Zhang W, Nadeau KC, Leung DYM, Wills-Karp M.

J Allergy Clin Immunol. 2020 Jan 8. pii: S0091-6749(20)30001-4. doi: 10.1016/j.jaci.2019.11.048. [Epub ahead of print]


Sustained successful peanut oral immunotherapy associated with low basophil activation and peanut-specific IgE.

Tsai M, Mukai K, Chinthrajah RS, Nadeau KC, Galli SJ.

J Allergy Clin Immunol. 2019 Dec 2. pii: S0091-6749(19)31620-3. doi: 10.1016/j.jaci.2019.10.038. [Epub ahead of print]


The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors.

Balbino B, Herviou P, Godon O, Stackowicz J, Goff OR, Iannascoli B, Sterlin D, Brûlé S, Millot GA, Harris FM, Voronina VA, Nadeau KC, Macdonald LE, Murphy AJ, Bruhns P, Reber LL.

J Clin Invest. 2020 Jan 27. pii: 129697. doi: 10.1172/JCI129697. [Epub ahead of print]


Transcriptomic and methylomic features in asthmatic and nonasthmatic twins.

Dhondalay GKR, Bunning B, Bauer RN, Barnathan ES, Maniscalco C, Baribaud F, Nadeau KC, Andorf S.

Allergy. 2019 Nov 22. doi: 10.1111/all.14128. [Epub ahead of print] No abstract available.


Global metabolic profiling to model biological processes of aging in twins.

Bunning BJ, Contrepois K, Lee-McMullen B, Dhondalay GKR, Zhang W, Tupa D, Raeber O, Desai M, Nadeau KC, Snyder MP, Andorf S.

Aging Cell. 2020 Jan;19(1):e13073. doi: 10.1111/acel.13073. Epub 2019 Nov 19.


Can food allergy be cured? What are the future prospects?

Sampath V, Sindher SB, Alvarez Pinzon AM, Nadeau KC.

Allergy. 2019 Nov 16. doi: 10.1111/all.14116. [Epub ahead of print] Review.


Trends in egg specific immunoglobulin levels during natural tolerance and oral immunotherapy.

Andorf S, Bunning B, Tupa D, Cao S, Long AJ, Borres MP, Galli SJ, Chinthrajah RS, Nadeau KC.

Allergy. 2019 Nov 14. doi: 10.1111/all.14107. [Epub ahead of print] No abstract available.


Phase 2a randomized, placebo-controlled study of anti-IL-33 in peanut allergy.

Chinthrajah S, Cao S, Liu C, Lyu SC, Sindher SB, Long A, Sampath V, Petroni D, Londei M, Nadeau KC.

JCI Insight. 2019 Nov 14;4(22). pii: 131347. doi: 10.1172/jci.insight.131347.


Conflicting verdicts on peanut oral immunotherapy from the Institute for Clinical and Economic Review and US Food and Drug Administration Advisory Committee: Where do we go from here?

Eiwegger T, Anagnostou K, Arasi S, Bégin P, Ben-Shoshan M, Beyer K, Blumchen K, Brough H, Caubet JC, Chan ES, Chen M, Chinthrajah S, Davis CM, Des Roches A, Du Toit G, Elizur A, Galli SJ, Håland G, Hoffmann-Sommergruber K, Kim H, Leung DYM, Long A, Muraro A, Nurmatov UB, Pajno GB, Sampath V, Saxena J, Sindher S, Upton J, Worm M, Nadeau KC.

J Allergy Clin Immunol. 2019 Nov 1. pii: S0091-6749(19)31414-9. doi: 10.1016/j.jaci.2019.10.021. [Epub ahead of print] No abstract available.


Cow's Milk and Vitamin D Supplementation in Infants-Timing Is Everything.

du Toit G, Elizur A, Nadeau KC.

JAMA Pediatr. 2019 Oct 21. doi: 10.1001/jamapediatrics.2019.3560. [Epub ahead of print] No abstract available.


Natural Tr1-like cells do not confer long-term tolerogenic memory.

Yadava K, Medina CO, Ishak H, Gurevich I, Kuipers H, Shamskhou EA, Koliesnik IO, Moon JJ, Weaver C, Nadeau KC, Bollyky PL.

Elife. 2019 Oct 11;8. pii: e44821. doi: 10.7554/eLife.44821.


Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study.

Chinthrajah RS, Purington N, Andorf S, Long A, O'Laughlin KL, Lyu SC, Manohar M, Boyd SD, Tibshirani R, Maecker H, Plaut M, Mukai K, Tsai M, Desai M, Galli SJ, Nadeau KC.

Lancet. 2019 Oct 19;394(10207):1437-1449. doi: 10.1016/S0140-6736(19)31793-3. Epub 2019 Sep 12.


The future of omics for clinical practice.

Long A, Bunning B, Borro M, Sampath V, Nadeau KC.

Ann Allergy Asthma Immunol. 2019 Dec;123(6):535-536. doi: 10.1016/j.anai.2019.07.016. Epub 2019 Jul 26. No abstract available.


Almond (Prunus dulcis) Allergen Pru du 8, the First Member of a New Family of Food Allergens.

Che H, Zhang Y, Jiang S, Jin T, Lyu SC, Nadeau KC, McHugh T.

J Agric Food Chem. 2019 Aug 7;67(31):8626-8631. doi: 10.1021/acs.jafc.9b02781. Epub 2019 Jul 29.


Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells.

Lee WH, Ong SG, Zhou Y, Tian L, Bae HR, Baker N, Whitlatch A, Mohammadi L, Guo H, Nadeau KC, Springer ML, Schick SF, Bhatnagar A, Wu JC.

J Am Coll Cardiol. 2019 Jun 4;73(21):2722-2737. doi: 10.1016/j.jacc.2019.03.476.


Legends of Allergy: Stephen J. Galli.

Tsai M, Chinthrajah S, Nadeau KC.

Allergy. 2020 Jan;75(1):243-245. doi: 10.1111/all.13815. Epub 2019 Oct 23. No abstract available.


Newly identified T cell subsets in mechanistic studies of food immunotherapy.

Sampath V, Nadeau KC.

J Clin Invest. 2019 Apr 1;129(4):1431-1440. doi: 10.1172/JCI124605. Epub 2019 Apr 1. Review.


Changing Patient Mindsets about Non-Life-Threatening Symptoms During Oral Immunotherapy: A Randomized Clinical Trial.

Howe LC, Leibowitz KA, Perry MA, Bitler JM, Block W, Kaptchuk TJ, Nadeau KC, Crum AJ.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1550-1559. doi: 10.1016/j.jaip.2019.01.022. Epub 2019 Jan 23.


Prevalence and Severity of Food Allergies Among US Adults.

Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, Schleimer RP, Nadeau KC.

JAMA Netw Open. 2019 Jan 4;2(1):e185630. doi: 10.1001/jamanetworkopen.2018.5630.


Report from the National Institute of Allergy and Infectious Diseases workshop on "Atopic dermatitis and the atopic march: Mechanisms and interventions".

Davidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M.

J Allergy Clin Immunol. 2019 Mar;143(3):894-913. doi: 10.1016/j.jaci.2019.01.003. Epub 2019 Jan 9.


High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes.

Croote D, Darmanis S, Nadeau KC, Quake SR.

Science. 2018 Dec 14;362(6420):1306-1309. doi: 10.1126/science.aau2599.


Baseline Gastrointestinal Eosinophilia Is Common in Oral Immunotherapy Subjects With IgE-Mediated Peanut Allergy.

Wright BL, Fernandez-Becker NQ, Kambham N, Purington N, Tupa D, Zhang W, Rank MA, Kita H, Shim KP, Bunning BJ, Doyle AD, Jacobsen EA, Boyd SD, Tsai M, Maecker H, Manohar M, Galli SJ, Nadeau KC, Chinthrajah RS.

Front Immunol. 2018 Nov 22;9:2624. doi: 10.3389/fimmu.2018.02624. eCollection 2018.


Analysis of a Large Standardized Food Challenge Data Set to Determine Predictors of Positive Outcome Across Multiple Allergens.

Sindher S, Long AJ, Purington N, Chollet M, Slatkin S, Andorf S, Tupa D, Kumar D, Woch MA, O'Laughlin KL, Assaad A, Pongracic J, Spergel JM, Tam J, Tilles S, Wang J, Galli SJ, Nadeau KC, Chinthrajah RS.

Front Immunol. 2018 Nov 27;9:2689. doi: 10.3389/fimmu.2018.02689. eCollection 2018.


Identification of Almond ( Prunus dulcis) Vicilin As a Food Allergen.

Che H, Zhang Y, Lyu SC, Nadeau KC, McHugh T.

J Agric Food Chem. 2019 Jan 9;67(1):425-432. doi: 10.1021/acs.jafc.8b05290. Epub 2018 Dec 20.


Laundry detergents and detergent residue after rinsing directly disrupt tight junction barrier integrity in human bronchial epithelial cells.

Wang M, Tan G, Eljaszewicz A, Meng Y, Wawrzyniak P, Acharya S, Altunbulakli C, Westermann P, Dreher A, Yan L, Wang C, Akdis M, Zhang L, Nadeau KC, Akdis CA.

J Allergy Clin Immunol. 2019 May;143(5):1892-1903. doi: 10.1016/j.jaci.2018.11.016. Epub 2018 Nov 27.


The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States.

Gupta RS, Warren CM, Smith BM, Blumenstock JA, Jiang J, Davis MM, Nadeau KC.

Pediatrics. 2018 Dec;142(6). pii: e20181235. doi: 10.1542/peds.2018-1235. Epub 2018 Nov 19. Erratum in: Pediatrics. 2019 Mar;143(3):.


Differences in multiple immune parameters between Indian and U.S. infants.

Rathore DK, Holmes TH, Nadeau KC, Mittal P, Batra A, Rosenberg-Hasson Y, Sopory S, Gupta R, Chellani HK, Aggarwal KC, Bal V, Natchu UCM, Bhatnagar S, Tavassoli M, Lyell DJ, Rath S, Wadhwa N, Maecker HT.

PLoS One. 2018 Nov 16;13(11):e0207297. doi: 10.1371/journal.pone.0207297. eCollection 2018. Erratum in: PLoS One. 2019 Mar 28;14(3):e0214749.


Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies.

Stranks AJ, Minnicozzi SC, Miller SJ, Burton OT, Logsdon SL, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Schneider LC, Oettgen HC.

Ann Allergy Asthma Immunol. 2019 Feb;122(2):213-215. doi: 10.1016/j.anai.2018.10.024. Epub 2018 Nov 4. No abstract available.


Multicenter, randomized, double-blind, placebo-controlled clinical trial of vital wheat gluten oral immunotherapy.

Nowak-Węgrzyn A, Wood RA, Nadeau KC, Pongracic JA, Henning AK, Lindblad RW, Beyer K, Sampson HA.

J Allergy Clin Immunol. 2019 Feb;143(2):651-661.e9. doi: 10.1016/j.jaci.2018.08.041. Epub 2018 Oct 30.


Peanut-specific T cell responses in patients with different clinical reactivity.

Birrueta G, Tripple V, Pham J, Manohar M, James EA, Kwok WW, Nadeau KC, Sette A, Peters B, Schulten V.

PLoS One. 2018 Oct 10;13(10):e0204620. doi: 10.1371/journal.pone.0204620. eCollection 2018.


Eliciting Dose and Safety Outcomes From a Large Dataset of Standardized Multiple Food Challenges.

Purington N, Chinthrajah RS, Long A, Sindher S, Andorf S, O'Laughlin K, Woch MA, Scheiber A, Assa'ad A, Pongracic J, Spergel JM, Tam J, Tilles S, Wang J, Galli SJ, Desai M, Nadeau KC.

Front Immunol. 2018 Sep 21;9:2057. doi: 10.3389/fimmu.2018.02057. eCollection 2018.


Heterogeneity of Ara h Component-Specific CD4 T Cell Responses in Peanut-Allergic Subjects.

Renand A, Farrington M, Whalen E, Wambre E, Bajzik V, Chinthrajah S, Nadeau KC, Kwok WW.

Front Immunol. 2018 Jun 25;9:1408. doi: 10.3389/fimmu.2018.01408. eCollection 2018.


Development of a tool predicting severity of allergic reaction during peanut challenge.

Chinthrajah RS, Purington N, Andorf S, Rosa JS, Mukai K, Hamilton R, Smith BM, Gupta R, Galli SJ, Desai M, Nadeau KC.

Ann Allergy Asthma Immunol. 2018 Jul;121(1):69-76.e2. doi: 10.1016/j.anai.2018.04.020. Epub 2018 Apr 27.


High dimensional immune biomarkers demonstrate differences in phenotypes and endotypes in food allergy and asthma.

Chinthrajah RS, Purington N, Sampath V, Andorf S, Manohar M, Prunicki M, Zhou X, Tupa D, Nadeau KC.

Ann Allergy Asthma Immunol. 2018 Jul;121(1):117-119.e1. doi: 10.1016/j.anai.2018.04.022. Epub 2018 Apr 26. No abstract available.


Realizing the Paris Climate Agreement to Improve Cardiopulmonary Health. Where Science Meets Policy.

Rice MB, Motto Malea N, Pinkerton KE, Schwartz J, Nadeau KC, Browner CM, Whitehouse S, Thurston GD.

Ann Am Thorac Soc. 2018 Jul;15(7):791-798. doi: 10.1513/AnnalsATS.201803-203PS. Review. No abstract available.


New treatment directions in food allergy.

Sampath V, Sindher SB, Zhang W, Nadeau KC.

Ann Allergy Asthma Immunol. 2018 Mar;120(3):254-262. doi: 10.1016/j.anai.2018.01.004. Review. No abstract available.


The Use of Biomarkers to Predict Aero-Allergen and Food Immunotherapy Responses.

Sindher SB, Long A, Acharya S, Sampath V, Nadeau KC.

Clin Rev Allergy Immunol. 2018 Oct;55(2):190-204. doi: 10.1007/s12016-018-8678-z. Review.


Exposure to NO2, CO, and PM2.5 is linked to regional DNA methylation differences in asthma.

Prunicki M, Stell L, Dinakarpandian D, de Planell-Saguer M, Lucas RW, Hammond SK, Balmes JR, Zhou X, Paglino T, Sabatti C, Miller RL, Nadeau KC.

Clin Epigenetics. 2018 Jan 5;10:2. doi: 10.1186/s13148-017-0433-4. eCollection 2018.


Food allergy and omics.

Dhondalay GK, Rael E, Acharya S, Zhang W, Sampath V, Galli SJ, Tibshirani R, Boyd SD, Maecker H, Nadeau KC, Andorf S.

J Allergy Clin Immunol. 2018 Jan;141(1):20-29. doi: 10.1016/j.jaci.2017.11.007. Review.


Feasibility of sustained response through long-term dosing in food allergy immunotherapy.

Andorf S, Manohar M, Dominguez T, Block W, Tupa D, Kshirsagar RA, Sampath V, Chinthrajah RS, Nadeau KC.

Allergy Asthma Clin Immunol. 2017 Dec 21;13:52. doi: 10.1186/s13223-017-0224-7. eCollection 2017.


Observational long-term follow-up study of rapid food oral immunotherapy with omalizumab.

Andorf S, Manohar M, Dominguez T, Block W, Tupa D, Kshirsagar RA, Sampath V, Chinthrajah RS, Nadeau KC.

Allergy Asthma Clin Immunol. 2017 Dec 21;13:51. doi: 10.1186/s13223-017-0223-8. eCollection 2017.


Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE.

Tsai CT, Mukai K, Robinson PV, Gray MA, Waschmann MB, Lyu SC, Tsai M, Chinthrajah RS, Nadeau KC, Bertozzi CR, Galli SJ.

J Allergy Clin Immunol. 2018 May;141(5):1901-1904.e15. doi: 10.1016/j.jaci.2017.11.021. Epub 2017 Dec 14. No abstract available.


Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial.

Andorf S, Purington N, Block WM, Long AJ, Tupa D, Brittain E, Rudman Spergel A, Desai M, Galli SJ, Nadeau KC, Chinthrajah RS.

Lancet Gastroenterol Hepatol. 2018 Feb;3(2):85-94. doi: 10.1016/S2468-1253(17)30392-8. Epub 2017 Dec 12.


EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy.

Pajno GB, Fernandez-Rivas M, Arasi S, Roberts G, Akdis CA, Alvaro-Lozano M, Beyer K, Bindslev-Jensen C, Burks W, Ebisawa M, Eigenmann P, Knol E, Nadeau KC, Poulsen LK, van Ree R, Santos AF, du Toit G, Dhami S, Nurmatov U, Boloh Y, Makela M, O'Mahony L, Papadopoulos N, Sackesen C, Agache I, Angier E, Halken S, Jutel M, Lau S, Pfaar O, Ryan D, Sturm G, Varga EM, van Wijk RG, Sheikh A, Muraro A; EAACI Allergen Immunotherapy Guidelines Group.

Allergy. 2018 Apr;73(4):799-815. doi: 10.1111/all.13319. Epub 2017 Dec 5.


Identification, characterization, and initial epitope mapping of pine nut allergen Pin k 2.

Zhang Y, Du WX, Fan Y, Yi J, Lyu SC, Nadeau KC, McHugh TH.

Food Res Int. 2016 Dec;90:268-274. doi: 10.1016/j.foodres.2016.10.043. Epub 2016 Oct 26.


Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial.

Sampson HA, Shreffler WG, Yang WH, Sussman GL, Brown-Whitehorn TF, Nadeau KC, Cheema AS, Leonard SA, Pongracic JA, Sauvage-Delebarre C, Assa'ad AH, de Blay F, Bird JA, Tilles SA, Boralevi F, Bourrier T, Hébert J, Green TD, Gerth van Wijk R, Knulst AC, Kanny G, Schneider LC, Kowalski ML, Dupont C.

JAMA. 2017 Nov 14;318(18):1798-1809. doi: 10.1001/jama.2017.16591.


Erratum to: Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review.

Dhami S, Nurmatov U, Pajno GB, Fernandez-Rivas M, Muraro A, Roberts G, Akdis C, Alvaro-Lozano M, Beyer K, Bindslev-Jensen C, Burks W, du Toit G, Ebisawa M, Eigenmann P, Knol E, Makela M, Nadeau KC, O'Mahony L, Papadopoulos N, Poulsen L, Sackesen C, Sampson H, Santos A, van Ree R, Timmermans F, Sheikh A.

Clin Transl Allergy. 2017 Sep 15;7:31. doi: 10.1186/s13601-017-0166-7. eCollection 2017.


Immune monitoring for precision medicine in allergy and asthma.

Boyd SD, Hoh RA, Nadeau KC, Galli SJ.

Curr Opin Immunol. 2017 Oct;48:82-91. doi: 10.1016/j.coi.2017.08.007. Epub 2017 Sep 7. Review.

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