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Items: 1 to 50 of 52

1.

Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked.

Nacken W, Wixler V, Ehrhardt C, Ludwig S.

Cell Microbiol. 2017 Jul;19(7). doi: 10.1111/cmi.12721. Epub 2017 Jan 27.

PMID:
28076660
2.

Activation of c-jun N-terminal kinase upon influenza A virus (IAV) infection is independent of pathogen-related receptors but dependent on amino acid sequence variations of IAV NS1.

Nacken W, Anhlan D, Hrincius ER, Mostafa A, Wolff T, Sadewasser A, Pleschka S, Ehrhardt C, Ludwig S.

J Virol. 2014 Aug;88(16):8843-52. doi: 10.1128/JVI.00424-14. Epub 2014 May 28.

3.

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.

Kim HJ, Chang KA, Ha TY, Kim J, Ha S, Shin KY, Moon C, Nacken W, Kim HS, Suh YH.

PLoS One. 2014 Feb 25;9(2):e88924. doi: 10.1371/journal.pone.0088924. eCollection 2014.

4.

PAR1 contributes to influenza A virus pathogenicity in mice.

Khoufache K, Berri F, Nacken W, Vogel AB, Delenne M, Camerer E, Coughlin SR, Carmeliet P, Lina B, Rimmelzwaan GF, Planz O, Ludwig S, Riteau B.

J Clin Invest. 2013 Jan;123(1):206-14. doi: 10.1172/JCI61667. Epub 2012 Dec 3.

5.
6.

Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor.

Voss A, Gescher K, Hensel A, Nacken W, Zänker KS, Kerkhoff C.

FEBS Lett. 2012 Jan 20;586(2):196-203. doi: 10.1016/j.febslet.2011.12.022. Epub 2011 Dec 29.

7.

Double-stranded RNA induces MMP-9 gene expression in HaCaT keratinocytes by tumor necrosis factor-α.

Voss A, Gescher K, Hensel A, Nacken W, Kerkhoff C.

Inflamm Allergy Drug Targets. 2011 Jun;10(3):171-9.

PMID:
21428909
8.

Expression of S100A8/A9 in HaCaT keratinocytes alters the rate of cell proliferation and differentiation.

Voss A, Bode G, Sopalla C, Benedyk M, Varga G, Böhm M, Nacken W, Kerkhoff C.

FEBS Lett. 2011 Jan 21;585(2):440-6. doi: 10.1016/j.febslet.2010.12.037. Epub 2010 Dec 28.

9.

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells.

Loser K, Vogl T, Voskort M, Lueken A, Kupas V, Nacken W, Klenner L, Kuhn A, Foell D, Sorokin L, Luger TA, Roth J, Beissert S.

Nat Med. 2010 Jun;16(6):713-7. doi: 10.1038/nm.2150. Epub 2010 May 9.

PMID:
20473308
10.

Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans.

Urban CF, Ermert D, Schmid M, Abu-Abed U, Goosmann C, Nacken W, Brinkmann V, Jungblut PR, Zychlinsky A.

PLoS Pathog. 2009 Oct;5(10):e1000639. doi: 10.1371/journal.ppat.1000639. Epub 2009 Oct 30.

11.

Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia.

Ziegler G, Prinz V, Albrecht MW, Harhausen D, Khojasteh U, Nacken W, Endres M, Dirnagl U, Nietfeld W, Trendelenburg G.

Biochim Biophys Acta. 2009 Dec;1792(12):1198-204. doi: 10.1016/j.bbadis.2009.10.003. Epub 2009 Oct 14.

12.

Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis.

van Lent PL, Grevers LC, Blom AB, Arntz OJ, van de Loo FA, van der Kraan P, Abdollahi-Roodsaz S, Srikrishna G, Freeze H, Sloetjes A, Nacken W, Vogl T, Roth J, van den Berg WB.

Arthritis Rheum. 2008 Dec;58(12):3776-87. doi: 10.1002/art.24074.

13.

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein.

Cheng P, Corzo CA, Luetteke N, Yu B, Nagaraj S, Bui MM, Ortiz M, Nacken W, Sorg C, Vogl T, Roth J, Gabrilovich DI.

J Exp Med. 2008 Sep 29;205(10):2235-49. doi: 10.1084/jem.20080132. Epub 2008 Sep 22.

14.

Interaction between S100A8/A9 and annexin A6 is involved in the calcium-induced cell surface exposition of S100A8/A9.

Bode G, Lüken A, Kerkhoff C, Roth J, Ludwig S, Nacken W.

J Biol Chem. 2008 Nov 14;283(46):31776-84. doi: 10.1074/jbc.M803908200. Epub 2008 Sep 11.

15.

The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contacts.

Schnekenburger J, Schick V, Krüger B, Manitz MP, Sorg C, Nacken W, Kerkhoff C, Kahlert A, Mayerle J, Domschke W, Lerch MM.

J Cell Physiol. 2008 Aug;216(2):558-67. doi: 10.1002/jcp.21433.

PMID:
18452188
16.

Metal chelation and inhibition of bacterial growth in tissue abscesses.

Corbin BD, Seeley EH, Raab A, Feldmann J, Miller MR, Torres VJ, Anderson KL, Dattilo BM, Dunman PM, Gerads R, Caprioli RM, Nacken W, Chazin WJ, Skaar EP.

Science. 2008 Feb 15;319(5865):962-5. doi: 10.1126/science.1152449.

17.

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis.

van Lent PL, Grevers L, Blom AB, Sloetjes A, Mort JS, Vogl T, Nacken W, van den Berg WB, Roth J.

Ann Rheum Dis. 2008 Dec;67(12):1750-8. Epub 2007 Nov 30.

PMID:
18055478
18.

The hetero-oligomeric complex of the S100A8/S100A9 protein is extremely protease resistant.

Nacken W, Kerkhoff C.

FEBS Lett. 2007 Oct 30;581(26):5127-30. Epub 2007 Oct 8.

19.

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.

Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J.

Nat Med. 2007 Sep;13(9):1042-9. Epub 2007 Sep 2.

PMID:
17767165
20.

HaCaT keratinocytes overexpressing the S100 proteins S100A8 and S100A9 show increased NADPH oxidase and NF-kappaB activities.

Benedyk M, Sopalla C, Nacken W, Bode G, Melkonyan H, Banfi B, Kerkhoff C.

J Invest Dermatol. 2007 Aug;127(8):2001-11. Epub 2007 Apr 12.

21.

Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.

Ehrchen J, Steinmüller L, Barczyk K, Tenbrock K, Nacken W, Eisenacher M, Nordhues U, Sorg C, Sunderkötter C, Roth J.

Blood. 2007 Feb 1;109(3):1265-74. Epub 2006 Oct 3.

PMID:
17018861
22.

The response of the novel pro-inflammatory molecules S100A8/A9 to exercise.

Mooren FC, Lechtermann A, Fobker M, Brandt B, Sorg C, Völker K, Nacken W.

Int J Sports Med. 2006 Sep;27(9):751-8.

PMID:
16944403
23.

Role of the aryl hydrocarbon receptor in thymocyte emigration in vivo.

Temchura VV, Frericks M, Nacken W, Esser C.

Eur J Immunol. 2005 Sep;35(9):2738-47.

24.

S100A9 deficiency alters adenosine-5'-triphosphate induced calcium signalling but does not generally interfere with calcium and zinc homeostasis in murine neutrophils.

Nacken W, Mooren FC, Manitz MP, Bode G, Sorg C, Kerkhoff C.

Int J Biochem Cell Biol. 2005 Jun;37(6):1241-53. Epub 2005 Jan 27.

PMID:
15778088
25.

Computational searches for missing orthologs: the case of S100A12 in mice.

Fuellen G, Nacken W, Sorg C, Kerkhoff C.

OMICS. 2004 Winter;8(4):334-40.

PMID:
15703480
26.

The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.

Kerkhoff C, Nacken W, Benedyk M, Dagher MC, Sopalla C, Doussiere J.

FASEB J. 2005 Mar;19(3):467-9. Epub 2005 Jan 10.

PMID:
15642721
27.

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.

Vogl T, Ludwig S, Goebeler M, Strey A, Thorey IS, Reichelt R, Foell D, Gerke V, Manitz MP, Nacken W, Werner S, Sorg C, Roth J.

Blood. 2004 Dec 15;104(13):4260-8. Epub 2004 Aug 26.

PMID:
15331440
28.

The myeloid expressed EF-hand proteins display a diverse pattern of lipid raft association.

Nacken W, Sorg C, Kerkhoff C.

FEBS Lett. 2004 Aug 13;572(1-3):289-93.

29.

Absence of S100A12 in mouse: implications for RAGE-S100A12 interaction.

Fuellen G, Foell D, Nacken W, Sorg C, Kerkhoff C.

Trends Immunol. 2003 Dec;24(12):622-4. No abstract available.

PMID:
14644132
30.

Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis.

Foell D, Kane D, Bresnihan B, Vogl T, Nacken W, Sorg C, Fitzgerald O, Roth J.

Rheumatology (Oxford). 2003 Nov;42(11):1383-9. Epub 2003 Jun 27.

PMID:
12832707
31.

S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity.

Nacken W, Roth J, Sorg C, Kerkhoff C.

Microsc Res Tech. 2003 Apr 15;60(6):569-80. Review.

PMID:
12645005
32.

Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro.

Manitz MP, Horst B, Seeliger S, Strey A, Skryabin BV, Gunzer M, Frings W, Schönlau F, Roth J, Sorg C, Nacken W.

Mol Cell Biol. 2003 Feb;23(3):1034-43.

33.

Myeloid-related protein (MRP)-8 from cervico-vaginal secretions activates HIV replication.

Hashemi FB, Mollenhauer J, Madsen LD, Sha BE, Nacken W, Moyer MB, Sorg C, Spear GT.

AIDS. 2001 Mar 9;15(4):441-9.

PMID:
11242140
35.
37.

Zinc binding reverses the calcium-induced arachidonic acid-binding capacity of the S100A8/A9 protein complex.

Kerkhoff C, Vogl T, Nacken W, Sopalla C, Sorg C.

FEBS Lett. 1999 Oct 22;460(1):134-8.

40.

Members of the AAA-gene family are involved in early embryogenesis of vertebrates.

Nacken W.

Biochim Biophys Acta. 1997 Oct 9;1354(1):1-6.

PMID:
9375782
41.

The heterodimer of the Ca2+-binding proteins MRP8 and MRP14 binds to arachidonic acid.

Klempt M, Melkonyan H, Nacken W, Wiesmann D, Holtkemper U, Sorg C.

FEBS Lett. 1997 May 12;408(1):81-4.

42.

Molecular characterisation of the genomic locus of the mouse MRP8 gene.

Nacken W, Manitz MP, Sorg C.

Biochim Biophys Acta. 1996 Jan 17;1315(1):1-5.

44.

A homologue of the human MSS1 gene, a positive modulator of HIV-1 gene expression, is massively expressed in Xenopus oocytes.

Nacken W, Kingsman AJ, Kingsman SM, Sablitzky F, Sorg C.

Biochim Biophys Acta. 1995 Apr 4;1261(2):293-5.

PMID:
7711076
45.

Identification of a novel HIV-1 TAR RNA bulge binding protein.

Baker B, Muckenthaler M, Vives E, Blanchard A, Braddock M, Nacken W, Kingsman AJ, Kingsman SM.

Nucleic Acids Res. 1994 Aug 25;22(16):3365-72.

46.

Anther-specific expression of the rolB gene of Agrobacterium rhizogenes increases IAA content in anthers and alters anther development and whole flower growth.

Spena A, Estruch JJ, Prinsen E, Nacken W, Van Onckelen H, Sommer H.

Theor Appl Genet. 1992 Aug;84(5-6):520-7. doi: 10.1007/BF00224147.

PMID:
24201336
47.
48.
49.
50.

Molecular analysis of tap2, an anther-specific gene from Antirrhinum majus.

Nacken WK, Huijser P, Saedler H, Sommer H.

FEBS Lett. 1991 Mar 11;280(1):155-8.

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