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Items: 40

1.

XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures.

Ellwanger K, Briese S, Arnold C, Kienes I, Heim V, Nachbur U, Kufer TA.

Life Sci Alliance. 2019 Jul 26;2(4). pii: e201900346. doi: 10.26508/lsa.201900346. Print 2019 Aug.

2.

The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development.

Santa-Cecília FV, Ferreira DW, Guimaraes RM, Cecilio NT, Fonseca MM, Lopes AH, Davoli-Ferreira M, Kusuda R, Souza GR, Nachbur U, Alves-Filho JC, Teixeira MM, Zamboni DS, Cunha FQ, Cunha TM.

Pain. 2019 Jan;160(1):102-116. doi: 10.1097/j.pain.0000000000001383.

PMID:
30169421
3.

IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans.

Stafford CA, Lawlor KE, Heim VJ, Bankovacki A, Bernardini JP, Silke J, Nachbur U.

Cell Rep. 2018 Feb 6;22(6):1496-1508. doi: 10.1016/j.celrep.2018.01.024.

4.

NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells.

Tran LS, Tran D, De Paoli A, D'Costa K, Creed SJ, Ng GZ, Le L, Sutton P, Silke J, Nachbur U, Ferrero RL.

Cell Microbiol. 2018 May;20(5):e12826. doi: 10.1111/cmi.12826. Epub 2018 Feb 15.

PMID:
29392836
5.

A novel nucleotide oligomerisation domain 2 mutation in a family with Blau syndrome: Phenotype and function.

Ong LT, Nachbur U, Rowczenio D, Ziegler JB, Fischer E, Lin MW.

Innate Immun. 2017 Oct;23(7):578-583. doi: 10.1177/1753425917727063. Epub 2017 Aug 24.

PMID:
28836875
6.

Correction: TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1.

Etemadi N, Chopin M, Anderton H, Tanzer MC, Rickard JA, Abeysekera W, Hall C, Spall SK, Wang B, Xiong Y, Hla T, Pitson SM, Bonder CS, Wong WW, Ernst M, Smyth GK, Vaux DL, Nutt SL, Nachbur U, Silke J.

Elife. 2017 Jun 27;6. pii: e29849. doi: 10.7554/eLife.29849. No abstract available.

7.

Erratum: EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.

Pearson JS, Giogha C, Mühlen S, Nachbur U, Pham CL, Zhang Y, Hildebrand JM, Oates CV, Lung TW, Ingle D, Dagley LF, Bankovacki A, Petrie EJ, Schroeder GN, Crepin VF, Frankel G, Masters SL, Vince J, Murphy JM, Sunde M, Webb AI, Silke J, Hartland EL.

Nat Microbiol. 2017 Feb 13;2:17024. doi: 10.1038/nmicrobiol.2017.24. No abstract available.

8.

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.

Pearson JS, Giogha C, Mühlen S, Nachbur U, Pham CL, Zhang Y, Hildebrand JM, Oates CV, Lung TW, Ingle D, Dagley LF, Bankovacki A, Petrie EJ, Schroeder GN, Crepin VF, Frankel G, Masters SL, Vince J, Murphy JM, Sunde M, Webb AI, Silke J, Hartland EL.

Nat Microbiol. 2017 Jan 13;2:16258. doi: 10.1038/nmicrobiol.2016.258. Erratum in: Nat Microbiol. 2017 Feb 13;2:17024.

9.

RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.

Schneider AT, Gautheron J, Feoktistova M, Roderburg C, Loosen SH, Roy S, Benz F, Schemmer P, Büchler MW, Nachbur U, Neumann UP, Tolba R, Luedde M, Zucman-Rossi J, Panayotova-Dimitrova D, Leverkus M, Preisinger C, Tacke F, Trautwein C, Longerich T, Vucur M, Luedde T.

Cancer Cell. 2017 Jan 9;31(1):94-109. doi: 10.1016/j.ccell.2016.11.009. Epub 2016 Dec 22.

10.

Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.

Grabinger T, Bode KJ, Demgenski J, Seitz C, Delgado ME, Kostadinova F, Reinhold C, Etemadi N, Wilhelm S, Schweinlin M, Hänggi K, Knop J, Hauck C, Walles H, Silke J, Wajant H, Nachbur U, W Wei-Lynn W, Brunner T.

Gastroenterology. 2017 Mar;152(4):867-879. doi: 10.1053/j.gastro.2016.11.019. Epub 2016 Nov 24.

11.

A NODding acquaintance with ER stress.

Stafford CA, Nachbur U.

Cell Death Discov. 2016 May 30;2:16037. doi: 10.1038/cddiscovery.2016.37. eCollection 2016. No abstract available.

12.

Hepatitis C-induced hepatocyte apoptosis following liver transplantation is enhanced by immunosuppressive agents.

Lim EJ, Chin R, Nachbur U, Silke J, Jia Z, Angus PW, Torresi J.

J Viral Hepat. 2016 Sep;23(9):730-43. doi: 10.1111/jvh.12541. Epub 2016 May 11.

PMID:
27167351
13.

Lentiviral Vectors to Analyze Cell Death Regulators.

Nachbur U, Brumatti G.

Methods Mol Biol. 2016;1419:265-76. doi: 10.1007/978-1-4939-3581-9_19.

PMID:
27108445
14.

Killing Lymphoma with Smac-Mimetics: As Easy as ABC?

Nachbur U, Silke J.

Cancer Cell. 2016 Apr 11;29(4):425-427. doi: 10.1016/j.ccell.2016.03.018.

15.

In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8.

Gentle IE, Wong WW, Evans JM, Bankovacki A, Cook WD, Khan NR, Nachbur U, Rickard J, Anderton H, Moulin M, Lluis JM, Moujalled DM, Silke J, Vaux DL.

J Biol Chem. 2016 Jan 29;291(5):2547. doi: 10.1074/jbc.A110.216226. No abstract available.

16.

TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1.

Etemadi N, Chopin M, Anderton H, Tanzer MC, Rickard JA, Abeysekera W, Hall C, Spall SK, Wang B, Xiong Y, Hla T, Pitson SM, Bonder CS, Wong WW, Ernst M, Smyth GK, Vaux DL, Nutt SL, Nachbur U, Silke J.

Elife. 2015 Dec 23;4. pii: e10592. doi: 10.7554/eLife.10592. Erratum in: Elife. 2017 Jun 27;6:.

17.

Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation.

Lim EJ, Chin R, Nachbur U, Silke J, Jia Z, Angus PW, Torresi J.

PLoS One. 2015 Sep 21;10(9):e0138522. doi: 10.1371/journal.pone.0138522. eCollection 2015.

18.

Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis.

Ebert G, Allison C, Preston S, Cooney J, Toe JG, Stutz MD, Ojaimi S, Baschuk N, Nachbur U, Torresi J, Silke J, Begley CG, Pellegrini M.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5803-8. doi: 10.1073/pnas.1502400112. Epub 2015 Apr 20.

19.

Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.

Ebert G, Preston S, Allison C, Cooney J, Toe JG, Stutz MD, Ojaimi S, Scott HW, Baschuk N, Nachbur U, Torresi J, Chin R, Colledge D, Li X, Warner N, Revill P, Bowden S, Silke J, Begley CG, Pellegrini M.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5797-802. doi: 10.1073/pnas.1502390112. Epub 2015 Apr 20.

20.

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production.

Nachbur U, Stafford CA, Bankovacki A, Zhan Y, Lindqvist LM, Fiil BK, Khakham Y, Ko HJ, Sandow JJ, Falk H, Holien JK, Chau D, Hildebrand J, Vince JE, Sharp PP, Webb AI, Jackman KA, Mühlen S, Kennedy CL, Lowes KN, Murphy JM, Gyrd-Hansen M, Parker MW, Hartland EL, Lew AM, Huang DC, Lessene G, Silke J.

Nat Commun. 2015 Mar 17;6:6442. doi: 10.1038/ncomms7442.

PMID:
25778803
21.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.

22.

Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis.

Lim EJ, El Khobar K, Chin R, Earnest-Silveira L, Angus PW, Bock CT, Nachbur U, Silke J, Torresi J.

J Gen Virol. 2014 Oct;95(Pt 10):2204-15. doi: 10.1099/vir.0.065862-0. Epub 2014 Jun 27.

PMID:
24973240
23.

Response to the letter to the editor.

Etemadi N, Silke J, Nachbur U.

Immunol Cell Biol. 2014 Apr;92(4):301-2. doi: 10.1038/icb.2014.9. No abstract available.

PMID:
24751613
24.

Progranulin does not inhibit TNF and lymphotoxin-α signalling through TNF receptor 1.

Etemadi N, Webb A, Bankovacki A, Silke J, Nachbur U.

Immunol Cell Biol. 2013 Nov-Dec;91(10):661-4. doi: 10.1038/icb.2013.53. Epub 2013 Oct 8.

PMID:
24100384
25.

A type III effector antagonizes death receptor signalling during bacterial gut infection.

Pearson JS, Giogha C, Ong SY, Kennedy CL, Kelly M, Robinson KS, Lung TW, Mansell A, Riedmaier P, Oates CV, Zaid A, Mühlen S, Crepin VF, Marches O, Ang CS, Williamson NA, O'Reilly LA, Bankovacki A, Nachbur U, Infusini G, Webb AI, Silke J, Strasser A, Frankel G, Hartland EL.

Nature. 2013 Sep 12;501(7466):247-51. doi: 10.1038/nature12524.

26.

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.

Etemadi N, Holien JK, Chau D, Dewson G, Murphy JM, Alexander WS, Parker MW, Silke J, Nachbur U.

FEBS J. 2013 Nov;280(21):5283-97. doi: 10.1111/febs.12419. Epub 2013 Aug 2.

27.

Is BID required for NOD signalling?

Nachbur U, Vince JE, O'Reilly LA, Strasser A, Silke J.

Nature. 2012 Aug 23;488(7412):E4-6; discussion E6-8. doi: 10.1038/nature11366. No abstract available. Erratum in: Nature. 2012 Nov 29;491(7426):784.

PMID:
22914170
28.

The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.

Damgaard RB, Nachbur U, Yabal M, Wong WW, Fiil BK, Kastirr M, Rieser E, Rickard JA, Bankovacki A, Peschel C, Ruland J, Bekker-Jensen S, Mailand N, Kaufmann T, Strasser A, Walczak H, Silke J, Jost PJ, Gyrd-Hansen M.

Mol Cell. 2012 Jun 29;46(6):746-58. doi: 10.1016/j.molcel.2012.04.014. Epub 2012 May 17.

29.

Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel.

Sidler D, Brockmann A, Mueller J, Nachbur U, Corazza N, Renzulli P, Hemphill A, Brunner T.

Oncogene. 2012 Sep 13;31(37):4095-106. doi: 10.1038/onc.2011.575. Epub 2011 Dec 12.

PMID:
22158036
30.

Linear ubiquitination prevents inflammation and regulates immune signalling.

Gerlach B, Cordier SM, Schmukle AC, Emmerich CH, Rieser E, Haas TL, Webb AI, Rickard JA, Anderton H, Wong WW, Nachbur U, Gangoda L, Warnken U, Purcell AW, Silke J, Walczak H.

Nature. 2011 Mar 31;471(7340):591-6. doi: 10.1038/nature09816.

PMID:
21455173
31.

In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8.

Gentle IE, Wong WW, Evans JM, Bankovacki A, Cook WD, Khan NR, Nachbur U, Rickard J, Anderton H, Moulin M, Lluis JM, Moujalled DM, Silke J, Vaux DL.

J Biol Chem. 2011 Apr 15;286(15):13282-91. doi: 10.1074/jbc.M110.216226. Epub 2011 Feb 21. Erratum in: J Biol Chem. 2016 Jan 29;291(5):2547.

32.

TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.

Lluis JM, Nachbur U, Cook WD, Gentle IE, Moujalled D, Moulin M, Wong WW, Khan N, Chau D, Callus BA, Vince JE, Silke J, Vaux DL.

PLoS One. 2010 Jan 8;5(1):e8620. doi: 10.1371/journal.pone.0008620. Erratum in: PLoS One. 2010;5(12) doi: 10.1371/annotation/4e35cd59-c68f-4020-addb-18eb896112c5.

33.

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

Wong WW, Gentle IE, Nachbur U, Anderton H, Vaux DL, Silke J.

Cell Death Differ. 2010 Mar;17(3):482-7. doi: 10.1038/cdd.2009.178. Epub 2009 Nov 20.

34.

Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus.

Chin R, Nachbur U, Earnest-Silveira L, Bankovacki A, Koeberlein B, Zentgraf H, Bock CT, Silke J, Torresi J.

Virus Res. 2010 Jan;147(1):7-16. doi: 10.1016/j.virusres.2009.09.012. Epub 2009 Sep 26.

PMID:
19786052
35.

XIAP discriminates between type I and type II FAS-induced apoptosis.

Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T.

Nature. 2009 Aug 20;460(7258):1035-9. doi: 10.1038/nature08229. Epub 2009 Jul 22.

36.

Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells.

Kassahn D, Nachbur U, Conus S, Micheau O, Schneider P, Simon HU, Brunner T.

Cell Death Differ. 2009 Jan;16(1):115-24. doi: 10.1038/cdd.2008.133. Epub 2008 Sep 12.

37.

Thiazolides inhibit growth and induce glutathione-S-transferase Pi (GSTP1)-dependent cell death in human colon cancer cells.

Müller J, Sidler D, Nachbur U, Wastling J, Brunner T, Hemphill A.

Int J Cancer. 2008 Oct 15;123(8):1797-806. doi: 10.1002/ijc.23755.

38.

CD95L pro-drug: a novel Swiss Army Knife in cancer therapy?

Kassahn D, Nachbur U, Brunner T.

Cell Death Differ. 2007 Mar;14(3):393-4. Epub 2006 Dec 8. No abstract available.

39.

Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts.

Nachbur U, Kassahn D, Yousefi S, Legler DF, Brunner T.

Blood. 2006 Apr 1;107(7):2790-6. Epub 2005 Dec 6.

40.

Regulation of activation-induced Fas (CD95/Apo-1) ligand expression in T cells by the cyclin B1/Cdk1 complex.

Torgler R, Jakob S, Ontsouka E, Nachbur U, Mueller C, Green DR, Brunner T.

J Biol Chem. 2004 Sep 3;279(36):37334-42. Epub 2004 Jun 23.

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