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Items: 1 to 50 of 96

1.

[Telomerase, elixir of life for human cells?].

Rufer N, Nabholz M.

Med Sci (Paris). 2003 Mar;19(3):345-50. Review. French.

2.

Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.

Rufer N, Zippelius A, Batard P, Pittet MJ, Kurth I, Corthesy P, Cerottini JC, Leyvraz S, Roosnek E, Nabholz M, Romero P.

Blood. 2003 Sep 1;102(5):1779-87. Epub 2003 May 15.

3.

A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed.

Reichenbach P, Höss M, Azzalin CM, Nabholz M, Bucher P, Lingner J.

Curr Biol. 2003 Apr 1;13(7):568-74.

4.

A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin.

Szutorisz H, Lingner J, Cuthbert AP, Trott DA, Newbold RF, Nabholz M.

Cancer Res. 2003 Feb 1;63(3):689-95.

6.

Detection of promoter activity by flow cytometric analysis of GFP reporter expression.

Ducrest AL, Amacker M, Lingner J, Nabholz M.

Nucleic Acids Res. 2002 Jul 15;30(14):e65.

7.

Regulation of the human telomerase reverse transcriptase gene.

Ducrest AL, Szutorisz H, Lingner J, Nabholz M.

Oncogene. 2002 Jan 21;21(4):541-52. Review.

8.

Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.

Ducrest AL, Amacker M, Mathieu YD, Cuthbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J.

Cancer Res. 2001 Oct 15;61(20):7594-602.

9.

Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas.

Szutorisz H, Palmqvist R, Roos G, Stenling R, Schorderet DF, Reddel R, Lingner J, Nabholz M.

Oncogene. 2001 May 3;20(20):2600-5.

10.

DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites.

Ehret GB, Reichenbach P, Schindler U, Horvath CM, Fritz S, Nabholz M, Bucher P.

J Biol Chem. 2001 Mar 2;276(9):6675-88. Epub 2000 Oct 26.

11.

Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization.

Migliaccio M, Amacker M, Just T, Reichenbach P, Valmori D, Cerottini JC, Romero P, Nabholz M.

J Immunol. 2000 Nov 1;165(9):4978-84.

12.
14.

Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor alpha gene transcription.

Meyer WK, Reichenbach P, Schindler U, Soldaini E, Nabholz M.

J Biol Chem. 1997 Dec 12;272(50):31821-8.

15.

A conserved IL-2 responsive enhancer in the IL-2R alpha gene.

Bucher P, Corthésy P, Imbert J, Nabholz M.

Immunobiology. 1997 Dec;198(1-3):136-43. Review.

PMID:
9442385
16.

Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene.

Serdobova I, Pla M, Reichenbach P, Sperisen P, Ghysdael J, Wilson A, Freeman J, Nabholz M.

J Exp Med. 1997 Apr 7;185(7):1211-21.

17.

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

Lécine P, Algarté M, Rameil P, Beadling C, Bucher P, Nabholz M, Imbert J.

Mol Cell Biol. 1997 Apr;17(4):2351. No abstract available.

18.

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

Lécine P, Algarté M, Rameil P, Beadling C, Bucher P, Nabholz M, Imbert J.

Mol Cell Biol. 1996 Dec;16(12):6829-40. Erratum in: Mol Cell Biol. 1997 Apr;17(4):2351.

19.

The cis-acting elements controlling mouse IL-2R alpha transcription.

Nabholz M, Soldaini E, Sperisen P, Pla M, Wang SM, MacDonald HR, Reichenbach P, Beermann F, Bucher P.

Immunobiology. 1995 Jul;193(2-4):259-62. Review. No abstract available.

PMID:
8530152
20.

Mouse interleukin-2 receptor alpha gene expression. Interleukin-1 and interleukin-2 control transcription via distinct cis-acting elements.

Sperisen P, Wang SM, Soldaini E, Pla M, Rusterholz C, Bucher P, Corthésy P, Reichenbach P, Nabholz M.

J Biol Chem. 1995 May 5;270(18):10743-53.

21.

Mouse interleukin-2 receptor alpha gene expression. Delimitation of cis-acting regulatory elements in transgenic mice and by mapping of DNase-I hypersensitive sites.

Soldaini E, Pla M, Beermann F, Espel E, Corthésy P, Barangé S, Waanders GA, MacDonald HR, Nabholz M.

J Biol Chem. 1995 May 5;270(18):10733-42.

22.

Interleukins (IL)-1 and IL-2 control IL-2 receptor alpha and beta expression in immature thymocytes.

Wilson A, Corthésy P, Reichenbach P, MacDonald HR, Nabholz M.

Eur J Immunol. 1994 Aug;24(8):1729-35.

PMID:
8056031
23.

Characterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kappa B) element.

Lattion AL, Espel E, Reichenbach P, Fromental C, Bucher P, Israël A, Baeuerle P, Rice NR, Nabholz M.

Mol Cell Biol. 1992 Nov;12(11):5217-27.

25.

A PCR-based assay for reporter gene expression.

Sperisen P, Wang SM, Reichenbach P, Nabholz M.

PCR Methods Appl. 1992 Feb;1(3):164-70.

26.

Control of IL-2 receptor-alpha expression by IL-1, tumor necrosis factor, and IL-2. Complex regulation via elements in the 5' flanking region.

Plaetinck G, Combe MC, Corthésy P, Sperisen P, Kanamori H, Honjo T, Nabholz M.

J Immunol. 1990 Nov 15;145(10):3340-7.

PMID:
2230118
27.

Cell specificity of granzyme gene expression.

Garcia-Sanz JA, MacDonald HR, Jenne DE, Tschopp J, Nabholz M.

J Immunol. 1990 Nov 1;145(9):3111-8.

PMID:
2212674
28.

Activity and interleukin 1 responsiveness of SV40 enhancer motifs in a rodent immature T cell line.

Espel E, Fromental C, Reichenbach P, Nabholz M.

EMBO J. 1990 Mar;9(3):929-37.

29.

Perforin-mediated target cell lysis by cytolytic T lymphocytes.

Tschopp J, Nabholz M.

Annu Rev Immunol. 1990;8:279-302. Review. No abstract available.

PMID:
2188665
30.

Short-term culture of spleen lymphocytes for chromosome analysis of small rodents.

Jotterand Bellomo M, Mühlematter D, Nabholz M.

Genetica. 1990;83(1):51-60.

PMID:
2090561
31.

Loss of interleukin 2 dependence in cloned interleukin 2-dependent rat T lymphocyte x BW5147 hybridomas is not associated with segregation of a specific pair of rat chromosomes.

Somoza C, Fernández-Ruiz E, Jotterand-Bellomo M, Sanz E, Nabholz M, Silva A.

Eur J Immunol. 1989 Jul;19(7):1177-81.

PMID:
2788090
32.

Interleukin 1 and tumor necrosis factor enhance transcription from the SV40 early promoter in a T cell line.

Plaetinck G, Combe MC, Corthésy P, Seckinger P, Nabholz M.

Eur J Immunol. 1989 May;19(5):897-904.

PMID:
2544433
33.

CTL-mediated cytolysis: perforin and alternative pathways?

Nabholz M, Tschopp J.

Immunol Lett. 1989 Feb;20(3):179-80. No abstract available.

PMID:
2785499
34.

Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli.

Garcia-Sanz JA, Velotti F, MacDonald HR, Masson D, Tschopp J, Nabholz M.

Immunology. 1988 May;64(1):129-34.

35.

Recombinant tumor necrosis factor can induce interleukin 2 receptor expression and cytolytic activity in a rat x mouse T cell hybrid.

Plaetinck G, Declercq W, Tavernier J, Nabholz M, Fiers W.

Eur J Immunol. 1987 Dec;17(12):1835-8.

PMID:
3121359
36.

Granzyme A secretion by normal activated Lyt-2+ and L3T4+ T cells in response to antigenic stimulation.

Velotti F, MacDonald HR, Nabholz M.

Eur J Immunol. 1987 Aug;17(8):1095-9.

PMID:
2957213
37.

Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin 2 receptor: relationship to the interleukin 2-binding site.

Moreau JL, Nabholz M, Diamantstein T, Malek T, Shevach E, Thèze J.

Eur J Immunol. 1987 Jul;17(7):929-35.

PMID:
2440696
38.

Interleukin 2 receptor traffic in a murine cytolytic T cell line.

Nabholz M, Combe MC, Corthésy P, Lowenthal J, Gabathuler R.

Eur J Immunol. 1987 Jun;17(6):783-90.

PMID:
3109923
39.

Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets.

Garcia-Sanz JA, Plaetinck G, Velotti F, Masson D, Tschopp J, MacDonald HR, Nabholz M.

EMBO J. 1987 Apr;6(4):933-8.

40.

The role of cytoplasmic granule components in cytolytic lymphocyte-mediated cytolysis.

Tschopp J, Nabholz M.

Ann Inst Pasteur Immunol. 1987 Mar-Apr;138(2):290-5. No abstract available.

PMID:
3111498
41.

The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14.

Brunet JF, Dosseto M, Denizot F, Mattei MG, Clark WR, Haqqi TM, Ferrier P, Nabholz M, Schmitt-Verhulst AM, Luciani MF, Golstein P.

Nature. 1986 Jul 17-23;322(6076):268-71.

PMID:
3090449
42.

Granules of cytolytic T-lymphocytes contain two serine esterases.

Masson D, Nabholz M, Estrade C, Tschopp J.

EMBO J. 1986 Jul;5(7):1595-600.

43.

Dissociation of interleukin 2-dependent and -independent B cell proliferation with monoclonal anti-interleukin 2 receptor antibody.

Hashimoto N, Nabholz M, MacDonald HR, Zubler RH.

Eur J Immunol. 1986 Mar;16(3):317-20.

PMID:
3082653
44.

T-cell activation.

MacDonald HR, Nabholz M.

Annu Rev Cell Biol. 1986;2:231-53. Review. No abstract available.

PMID:
3548767
45.

High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61.

Lowenthal JW, Corthésy P, Tougne C, Lees R, MacDonald HR, Nabholz M.

J Immunol. 1985 Dec;135(6):3988-94.

PMID:
3934270
46.
47.

Differential requirements for the induction of interleukin 2 responsiveness in L3T4+ and Lyt-2+ T cell subsets.

Erard F, Nabholz M, Dupuy-D'Angeac A, MacDonald HR.

J Exp Med. 1985 Nov 1;162(5):1738-43.

48.

Appearance of cytolytic granules upon induction of cytolytic activity in CTL-hybrids.

Masson D, Corthésy P, Nabholz M, Tschopp J.

EMBO J. 1985 Oct;4(10):2533-8.

49.
50.

Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes.

Lowenthal JW, Zubler RH, Nabholz M, MacDonald HR.

Nature. 1985 Jun 20-26;315(6021):669-72.

PMID:
3925347

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