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Items: 1 to 50 of 207

1.

Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.

Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC.

Nat Commun. 2017 Feb 16;8:14710. doi: 10.1038/ncomms14710. No abstract available.

2.

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.

Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC.

Nat Commun. 2016 Jun 24;7:11853. doi: 10.1038/ncomms11853.

3.

Heart Disease Prevention in Young Women: Sounding an Alarm.

Nabel EG.

Circulation. 2015 Sep 15;132(11):989-91. doi: 10.1161/CIRCULATIONAHA.115.018352. Epub 2015 Aug 24. No abstract available.

PMID:
26302760
4.

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

Ali ZA, de Jesus Perez V, Yuan K, Orcholski M, Pan S, Qi W, Chopra G, Adams C, Kojima Y, Leeper NJ, Qu X, Zaleta-Rivera K, Kato K, Yamada Y, Oguri M, Kuchinsky A, Hazen SL, Jukema JW, Ganesh SK, Nabel EG, Channon K, Leon MB, Charest A, Quertermous T, Ashley EA.

J Clin Invest. 2014 Dec;124(12):5159-74. doi: 10.1172/JCI77484. Epub 2014 Nov 17.

5.

Acceptance of the 2014 Association of American Physicians George M. Kober Medal. Giving back.

Nabel EG.

J Clin Invest. 2014 Jul;124(7):2831-4. doi: 10.1172/JCI77286. Epub 2014 Jul 1. No abstract available.

6.

The Women's Health Initiative--a victory for women and their health.

Nabel EG.

JAMA. 2013 Oct 2;310(13):1349-50. doi: 10.1001/jama.2013.278042. No abstract available.

PMID:
24084919
7.

Reflections on a life in biomedicine: leading change.

Nabel EG.

Yale J Biol Med. 2013 Sep 20;86(3):389-95. eCollection 2013 Sep.

8.

Balancing AMCs' missions and health care costs--mission impossible?

Nabel EG, Ferris TG, Slavin PL.

N Engl J Med. 2013 Sep 12;369(11):994-6. doi: 10.1056/NEJMp1309179. No abstract available.

PMID:
24024836
9.

Cardiovascular insights from a premature aging syndrome: a translational story.

Nabel EG.

Trans Am Clin Climatol Assoc. 2012;123:221-5; discussion 225-6.

10.

The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice.

Manceau V, Kremmer E, Nabel EG, Maucuer A.

PLoS One. 2012;7(8):e43946. doi: 10.1371/journal.pone.0043946. Epub 2012 Aug 24.

11.

A tale of coronary artery disease and myocardial infarction.

Nabel EG, Braunwald E.

N Engl J Med. 2012 Jan 5;366(1):54-63. doi: 10.1056/NEJMra1112570. No abstract available. Erratum in: N Engl J Med. 2012 Mar 8;366(10):970.

12.

Genomics of cardiovascular disease.

O'Donnell CJ, Nabel EG.

N Engl J Med. 2011 Dec 1;365(22):2098-109. doi: 10.1056/NEJMra1105239. Review. No abstract available.

13.

Prmt2 regulates the lipopolysaccharide-induced responses in lungs and macrophages.

Dalloneau E, Pereira PL, Brault V, Nabel EG, Hérault Y.

J Immunol. 2011 Nov 1;187(9):4826-34. doi: 10.4049/jimmunol.1101087. Epub 2011 Sep 28.

14.

Differential temporal and spatial progerin expression during closure of the ductus arteriosus in neonates.

Bökenkamp R, Raz V, Venema A, DeRuiter MC, van Munsteren C, Olive M, Nabel EG, Gittenberger-de Groot AC.

PLoS One. 2011;6(9):e23975. doi: 10.1371/journal.pone.0023975. Epub 2011 Sep 6. Erratum in: PLoS One. 2011;6(9). doi: 10.1371/annotation/c0198e87-d087-444c-8be9-780adb1582be.

15.

A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention.

Sampietro ML, Trompet S, Verschuren JJ, Talens RP, Deelen J, Heijmans BT, de Winter RJ, Tio RA, Doevendans PA, Ganesh SK, Nabel EG, Westra HJ, Franke L, van den Akker EB, Westendorp RG, Zwinderman AH, Kastrati A, Koch W, Slagboom PE, de Knijff P, Jukema JW.

Hum Mol Genet. 2011 Dec 1;20(23):4748-57. doi: 10.1093/hmg/ddr389. Epub 2011 Aug 30.

16.

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts.

Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS.

J Clin Invest. 2011 Jul;121(7):2833-44. doi: 10.1172/JCI43578. Epub 2011 Jun 13.

17.

Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly.

Kovacic JC, Moreno P, Nabel EG, Hachinski V, Fuster V.

Circulation. 2011 May 3;123(17):1900-10. doi: 10.1161/CIRCULATIONAHA.110.009118. Review. No abstract available.

PMID:
21537006
18.

Cellular senescence, vascular disease, and aging: Part 1 of a 2-part review.

Kovacic JC, Moreno P, Hachinski V, Nabel EG, Fuster V.

Circulation. 2011 Apr 19;123(15):1650-60. doi: 10.1161/CIRCULATIONAHA.110.007021. Review. No abstract available.

PMID:
21502583
19.

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect.

Verstraeten VL, Peckham LA, Olive M, Capell BC, Collins FS, Nabel EG, Young SG, Fong LG, Lammerding J.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4997-5002. doi: 10.1073/pnas.1019532108. Epub 2011 Mar 7.

20.

Time course analysis of gene expression identifies multiple genes with differential expression in patients with in-stent restenosis.

Ganesh SK, Joo J, Skelding K, Mehta L, Zheng G, O'Neill K, Billings EM, Helgadottir A, Andersen K, Thorgeirsson G, Gudnason T, Geller NL, Simari RD, Holmes DR, O'Neill WW, Nabel EG.

BMC Med Genomics. 2011 Feb 28;4:20. doi: 10.1186/1755-8794-4-20.

21.

Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.

Olive M, Harten I, Mitchell R, Beers JK, Djabali K, Cao K, Erdos MR, Blair C, Funke B, Smoot L, Gerhard-Herman M, Machan JT, Kutys R, Virmani R, Collins FS, Wight TN, Nabel EG, Gordon LB.

Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2301-9. doi: 10.1161/ATVBAHA.110.209460. Epub 2010 Aug 26.

22.

Disruption of protein arginine N-methyltransferase 2 regulates leptin signaling and produces leanness in vivo through loss of STAT3 methylation.

Iwasaki H, Kovacic JC, Olive M, Beers JK, Yoshimoto T, Crook MF, Tonelli LH, Nabel EG.

Circ Res. 2010 Oct 15;107(8):992-1001. doi: 10.1161/CIRCRESAHA.110.225326. Epub 2010 Aug 26.

23.

On board with the Cures Acceleration Network.

Nabel EG.

Sci Transl Med. 2010 May 19;2(32):32ed2. doi: 10.1126/scitranslmed.3001136. No abstract available.

24.

Deficiency of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1 accelerates atherogenesis in apolipoprotein E-deficient mice.

Akyürek LM, Boehm M, Olive M, Zhou AX, San H, Nabel EG.

Biochem Biophys Res Commun. 2010 May 28;396(2):359-63. doi: 10.1016/j.bbrc.2010.04.097. Epub 2010 Apr 24.

25.

Linking biomedical research to health care.

Nabel EG.

J Clin Invest. 2009 Oct;119(10):2858. No abstract available.

26.

Why data-sharing policies matter.

Guttmacher AE, Nabel EG, Collins FS.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16894. doi: 10.1073/pnas.0910378106. Epub 2009 Sep 18. No abstract available.

27.

The global alliance for chronic diseases.

Daar AS, Nabel EG, Pramming SK, Anderson W, Beaudet A, Liu D, Katoch VM, Borysiewicz LK, Glass RI, Bell J.

Science. 2009 Jun 26;324(5935):1642. doi: 10.1126/science.324_1642. No abstract available.

PMID:
19556484
28.

Combating chronic disease in developing countries.

Nabel EG, Stevens S, Smith R.

Lancet. 2009 Jun 13;373(9680):2004-6. doi: 10.1016/S0140-6736(09)61074-6. Review. No abstract available.

PMID:
19523681
29.
30.

Neuropilin-1 identifies endothelial precursors in human and murine embryonic stem cells before CD34 expression.

Cimato T, Beers J, Ding S, Ma M, McCoy JP, Boehm M, Nabel EG.

Circulation. 2009 Apr 28;119(16):2170-8. doi: 10.1161/CIRCULATIONAHA.109.849596. Epub 2009 Apr 13.

31.

Notes from the Director, National Heart, Lung, and Blood Institute: transitions.

Nabel EG.

Blood. 2009 Mar 26;113(13):2875-7. doi: 10.1182/blood-2008-12-194100.

32.

The cardiovascular programs of the National Heart, Lung, and Blood Institute: from vision to action to impact.

Nabel EG, Lauer MS.

J Am Coll Cardiol. 2009 Mar 24;53(12):1082-3. doi: 10.1016/j.jacc.2009.01.010. No abstract available.

33.

National Heart, Lung, and Blood Institute: transitions.

Nabel EG.

Circulation. 2009 Mar 17;119(10):1453-5. doi: 10.1161/CIRCULATIONAHA.108.841551. No abstract available.

34.

CABG vs. stenting--clinical implications of the SYNTAX trial.

Lee TH, Hillis LD, Nabel EG.

N Engl J Med. 2009 Feb 19;360(8):e10. doi: 10.1056/NEJMp0900462. No abstract available.

PMID:
19228613
35.

Notes from the NHLBI director: transitions.

Nabel EG.

Am J Respir Crit Care Med. 2009 Feb 15;179(4):263-4. doi: 10.1164/rccm.200812-1848ED. No abstract available.

PMID:
19201927
36.

KIS protects against adverse vascular remodeling by opposing stathmin-mediated VSMC migration in mice.

Langenickel TH, Olive M, Boehm M, San H, Crook MF, Nabel EG.

J Clin Invest. 2008 Dec;118(12):3848-59. doi: 10.1172/JCI33206. Epub 2008 Nov 13.

37.

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model.

Capell BC, Olive M, Erdos MR, Cao K, Faddah DA, Tavarez UL, Conneely KN, Qu X, San H, Ganesh SK, Chen X, Avallone H, Kolodgie FD, Virmani R, Nabel EG, Collins FS.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15902-7. doi: 10.1073/pnas.0807840105. Epub 2008 Oct 6. Erratum in: Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13143.

38.

Cardiovascular genomics, personalized medicine, and the National Heart, Lung, and Blood Institute: part I: the beginning of an era.

O'Donnell CJ, Nabel EG.

Circ Cardiovasc Genet. 2008 Oct;1(1):51-7. doi: 10.1161/CIRCGENETICS.108.813337. Review.

39.

Protecting aggregate genomic data.

Zerhouni EA, Nabel EG.

Science. 2008 Oct 3;322(5898):44. doi: 10.1126/science.1165490. Epub 2008 Sep 4. No abstract available.

PMID:
18772394
40.

A recommitment to sickle cell disease research.

Nabel EG, Shurin SB.

Blood. 2008 May 15;111(10):4852-3. doi: 10.1182/blood-2008-03-143685. No abstract available.

PMID:
18467610
41.

Gene transfer to arteries.

Akyürek LM, San H, Nabel EG, Singh R, Simari RD.

Curr Protoc Hum Genet. 2002 Feb;Chapter 13:Unit13.1. doi: 10.1002/0471142905.hg1301s31.

PMID:
18428325
42.

The physician-scientist: a value proposition.

Nabel EG.

J Clin Invest. 2008 Apr;118(4):1233-5. doi: 10.1172/JCI35074.

43.

Pharmacogenomics--ready for prime time?

Shurin SB, Nabel EG.

N Engl J Med. 2008 Mar 6;358(10):1061-3. doi: 10.1056/NEJMe0800801. No abstract available.

PMID:
18322288
44.

Phenotype and course of Hutchinson-Gilford progeria syndrome.

Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB, Brewer CC, Zalewski C, Kim HJ, Solomon B, Brooks BP, Gerber LH, Turner ML, Domingo DL, Hart TC, Graf J, Reynolds JC, Gropman A, Yanovski JA, Gerhard-Herman M, Collins FS, Nabel EG, Cannon RO 3rd, Gahl WA, Introne WJ.

N Engl J Med. 2008 Feb 7;358(6):592-604. doi: 10.1056/NEJMoa0706898.

45.

Notes from the NHLBI director: shaping the future of research--the NHLBI strategic plan.

Nabel EG.

Am J Respir Crit Care Med. 2007 Dec 15;176(12):1178. No abstract available.

PMID:
18057424
46.

Shaping the future of research: the NHLBI strategic plan.

Nabel EG.

Blood. 2007 Dec 15;110(13):4143. No abstract available.

PMID:
18056844
47.

Grand challenges in chronic non-communicable diseases.

Daar AS, Singer PA, Persad DL, Pramming SK, Matthews DR, Beaglehole R, Bernstein A, Borysiewicz LK, Colagiuri S, Ganguly N, Glass RI, Finegood DT, Koplan J, Nabel EG, Sarna G, Sarrafzadegan N, Smith R, Yach D, Bell J.

Nature. 2007 Nov 22;450(7169):494-6. No abstract available.

PMID:
18033288
48.
49.

Shaping the future of research: the NHLBI strategic plan.

Nabel EG.

Circ Res. 2007 Oct 26;101(9):849-50. No abstract available.

PMID:
17967791
50.

Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.

True AL, Olive M, Boehm M, San H, Westrick RJ, Raghavachari N, Xu X, Lynn EG, Sack MN, Munson PJ, Gladwin MT, Nabel EG.

Circ Res. 2007 Oct 26;101(9):893-901. Epub 2007 Sep 20.

PMID:
17885218

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