Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 68

1.

Whole-genome sequencing reveals nosocomial Clostridioides difficile transmission and a previously unsuspected epidemic scenario.

García-Fernández S, Frentrup M, Steglich M, Gonzaga A, Cobo M, López-Fresneña N, Cobo J, Morosini MI, Cantón R, Del Campo R, Nübel U.

Sci Rep. 2019 May 6;9(1):6959. doi: 10.1038/s41598-019-43464-4.

2.

Rapid cell division of Staphylococcus aureus during colonization of the human nose.

Szafrańska AK, Junker V, Steglich M, Nübel U.

BMC Genomics. 2019 Mar 20;20(1):229. doi: 10.1186/s12864-019-5604-6.

3.

Hospital outbreak due to Clostridium difficile ribotype 018 (RT018) in Southern Germany.

Berger FK, Gfrörer S, Becker SL, Baldan R, Cirillo DM, Frentrup M, Steglich M, Engling P, Nübel U, Mellmann A, Bischoff M, Gärtner B, von Müller L.

Int J Med Microbiol. 2019 May - Jun;309(3-4):189-193. doi: 10.1016/j.ijmm.2019.03.001. Epub 2019 Mar 5.

PMID:
30879971
4.

Identification of the novel class D β-lactamase OXA-679 involved in carbapenem resistance in Acinetobacter calcoaceticus.

Tietgen M, Kramer JS, Brunst S, Djahanschiri B, Wohra S, Higgins PG, Weidensdorfer M, Riedel-Christ S, Pos KM, Gonzaga A, Steglich M, Nübel U, Ebersberger I, Proschak E, Göttig S.

J Antimicrob Chemother. 2019 Jun 1;74(6):1494-1502. doi: 10.1093/jac/dkz080.

PMID:
30844059
5.

Discovery and Characterization of Mycobacterium basiliense sp. nov., a Nontuberculous Mycobacterium Isolated From Human Lungs.

Seth-Smith HMB, Imkamp F, Tagini F, Cuénod A, Hömke R, Jahn K, Tschacher A, Grendelmeier P, Bättig V, Erb S, Reinhard M, Rütimann G, Borrell S, Gagneux S, Casanova C, Droz S, Osthoff M, Tamm M, Nübel U, Greub G, Keller PM, Egli A.

Front Microbiol. 2019 Jan 8;9:3184. doi: 10.3389/fmicb.2018.03184. eCollection 2018.

6.

Genomic analysis of three Clostridioides difficile isolates from urban water sources.

Numberger D, Riedel T, McEwen G, Nübel U, Frentrup M, Schober I, Bunk B, Spröer C, Overmann J, Grossart HP, Greenwood AD.

Anaerobe. 2019 Apr;56:22-26. doi: 10.1016/j.anaerobe.2019.01.002. Epub 2019 Jan 8.

PMID:
30633971
7.

Compensatory evolution drives multidrug-resistant tuberculosis in Central Asia.

Merker M, Barbier M, Cox H, Rasigade JP, Feuerriegel S, Kohl TA, Diel R, Borrell S, Gagneux S, Nikolayevskyy V, Andres S, Nübel U, Supply P, Wirth T, Niemann S.

Elife. 2018 Oct 30;7. pii: e38200. doi: 10.7554/eLife.38200.

8.

A polyphasic approach leads to seven new species of the cellulose-decomposing genus Sorangium, Sorangium ambruticinum sp. nov., Sorangium arenae sp. nov., Sorangium bulgaricum sp. nov., Sorangium dawidii sp. nov., Sorangium kenyense sp. nov., Sorangium orientale sp. nov. and Sorangium reichenbachii sp. nov.

Mohr KI, Wolf C, Nübel U, Szafrańska AK, Steglich M, Hennessen F, Gemperlein K, Kämpfer P, Martin K, Müller R, Wink J.

Int J Syst Evol Microbiol. 2018 Nov;68(11):3576-3586. doi: 10.1099/ijsem.0.003034. Epub 2018 Sep 20.

PMID:
30234476
9.

Relevance of phenotypic information for the taxonomy of not-yet-cultured microorganisms.

Overmann J, Huang S, Nübel U, Hahnke RL, Tindall BJ.

Syst Appl Microbiol. 2019 Jan;42(1):22-29. doi: 10.1016/j.syapm.2018.08.009. Epub 2018 Aug 24.

PMID:
30197212
10.

Convergent Loss of ABC Transporter Genes From Clostridioides difficile Genomes Is Associated With Impaired Tyrosine Uptake and p-Cresol Production.

Steglich M, Hofmann JD, Helmecke J, Sikorski J, Spröer C, Riedel T, Bunk B, Overmann J, Neumann-Schaal M, Nübel U.

Front Microbiol. 2018 May 8;9:901. doi: 10.3389/fmicb.2018.00901. eCollection 2018.

11.

Nannocystis konarekensis sp. nov., a novel myxobacterium from an Iranian desert.

Mohr KI, Moradi A, Glaeser SP, Kämpfer P, Gemperlein K, Nübel U, Schumann P, Müller R, Wink J.

Int J Syst Evol Microbiol. 2018 Mar;68(3):721-729. doi: 10.1099/ijsem.0.002569. Epub 2018 Jan 18.

PMID:
29458458
12.

glnA Truncation in Salmonella enterica Results in a Small Colony Variant Phenotype, Attenuated Host Cell Entry, and Reduced Expression of Flagellin and SPI-1-Associated Effector Genes.

Aurass P, Düvel J, Karste S, Nübel U, Rabsch W, Flieger A.

Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e01838-17. doi: 10.1128/AEM.01838-17. Print 2018 Jan 15.

13.

Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study.

van Ingen J, Kohl TA, Kranzer K, Hasse B, Keller PM, Katarzyna Szafrańska A, Hillemann D, Chand M, Schreiber PW, Sommerstein R, Berger C, Genoni M, Rüegg C, Troillet N, Widmer AF, Becker SL, Herrmann M, Eckmanns T, Haller S, Höller C, Debast SB, Wolfhagen MJ, Hopman J, Kluytmans J, Langelaar M, Notermans DW, Ten Oever J, van den Barselaar P, Vonk ABA, Vos MC, Ahmed N, Brown T, Crook D, Lamagni T, Phin N, Smith EG, Zambon M, Serr A, Götting T, Ebner W, Thürmer A, Utpatel C, Spröer C, Bunk B, Nübel U, Bloemberg GV, Böttger EC, Niemann S, Wagner D, Sax H.

Lancet Infect Dis. 2017 Oct;17(10):1033-1041. doi: 10.1016/S1473-3099(17)30324-9. Epub 2017 Jul 12.

PMID:
28711585
14.

Rapid and Consistent Evolution of Colistin Resistance in Extensively Drug-Resistant Pseudomonas aeruginosa during Morbidostat Culture.

Dößelmann B, Willmann M, Steglich M, Bunk B, Nübel U, Peter S, Neher RA.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00043-17. doi: 10.1128/AAC.00043-17. Print 2017 Sep.

15.

The challenge of detecting indels in bacterial genomes from short-read sequencing data.

Steglich M, Nübel U.

J Biotechnol. 2017 May 20;250:11-15. doi: 10.1016/j.jbiotec.2017.02.026. Epub 2017 Mar 4.

PMID:
28267569
16.

Emergence and Spread of Antimicrobial Resistance: Recent Insights from Bacterial Population Genomics.

Nübel U.

Curr Top Microbiol Immunol. 2016;398:35-53. doi: 10.1007/82_2016_505. Review.

PMID:
27738914
17.

Comparison of six commercial kits to extract bacterial chromosome and plasmid DNA for MiSeq sequencing.

Becker L, Steglich M, Fuchs S, Werner G, Nübel U.

Sci Rep. 2016 Jun 17;6:28063. doi: 10.1038/srep28063.

18.

Tracing the Spread of Clostridium difficile Ribotype 027 in Germany Based on Bacterial Genome Sequences.

Steglich M, Nitsche A, von Müller L, Herrmann M, Kohl TA, Niemann S, Nübel U.

PLoS One. 2015 Oct 7;10(10):e0139811. doi: 10.1371/journal.pone.0139811. eCollection 2015.

19.

Molecular typing of toxic shock syndrome toxin-1- and Enterotoxin A-producing methicillin-sensitive Staphylococcus aureus isolates from an outbreak in a neonatal intensive care unit.

Layer F, Sanchini A, Strommenger B, Cuny C, Breier AC, Proquitté H, Bührer C, Schenkel K, Bätzing-Feigenbaum J, Greutelaers B, Nübel U, Gastmeier P, Eckmanns T, Werner G.

Int J Med Microbiol. 2015 Oct;305(7):790-8. doi: 10.1016/j.ijmm.2015.08.033. Epub 2015 Aug 22.

PMID:
26321006
20.

Whole genome sequence typing and microarray profiling of nasal and blood stream methicillin-resistant Staphylococcus aureus isolates: Clues to phylogeny and invasiveness.

Hamed M, Nitsche-Schmitz DP, Ruffing U, Steglich M, Dordel J, Nguyen D, Brink JH, Chhatwal GS, Herrmann M, Nübel U, Helms V, von Müller L.

Infect Genet Evol. 2015 Dec;36:475-482. doi: 10.1016/j.meegid.2015.08.020. Epub 2015 Aug 20.

PMID:
26297907
21.

Complete Genome Sequence of a CTX-M-15-Producing Klebsiella pneumoniae Outbreak Strain from Multilocus Sequence Type 514.

Becker L, Bunk B, Eller C, Steglich M, Pfeifer Y, Werner G, Nübel U.

Genome Announc. 2015 Jul 9;3(4). pii: e00742-15. doi: 10.1128/genomeA.00742-15.

22.

What caused the outbreak of ESBL-producing Klebsiella pneumoniae in a neonatal intensive care unit, Germany 2009 to 2012? Reconstructing transmission with epidemiological analysis and whole-genome sequencing.

Haller S, Eller C, Hermes J, Kaase M, Steglich M, Radonić A, Dabrowski PW, Nitsche A, Pfeifer Y, Werner G, Wunderle W, Velasco E, Abu Sin M, Eckmanns T, Nübel U.

BMJ Open. 2015 May 11;5(5):e007397. doi: 10.1136/bmjopen-2014-007397.

23.

Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40.

Zischka M, Künne CT, Blom J, Wobser D, Sakιnç T, Schmidt-Hohagen K, Dabrowski PW, Nitsche A, Hübner J, Hain T, Chakraborty T, Linke B, Goesmann A, Voget S, Daniel R, Schomburg D, Hauck R, Hafez HM, Tielen P, Jahn D, Solheim M, Sadowy E, Larsen J, Jensen LB, Ruiz-Garbajosa P, Quiñones Pérez D, Mikalsen T, Bender J, Steglich M, Nübel U, Witte W, Werner G.

BMC Genomics. 2015 Mar 12;16:175. doi: 10.1186/s12864-015-1367-x.

24.

Insufficient discriminatory power of MALDI-TOF mass spectrometry for typing of Enterococcus faecium and Staphylococcus aureus isolates.

Lasch P, Fleige C, Stämmler M, Layer F, Nübel U, Witte W, Werner G.

J Microbiol Methods. 2014 May;100:58-69. doi: 10.1016/j.mimet.2014.02.015. Epub 2014 Mar 12.

PMID:
24614010
25.

Phylogenetic analysis of Staphylococcus aureus CC398 reveals a sub-lineage epidemiologically associated with infections in horses.

Abdelbary MM, Wittenberg A, Cuny C, Layer F, Kurt K, Wieler LH, Walther B, Skov R, Larsen J, Hasman H, Fitzgerald JR, Smith TC, Wagenaar JA, Pantosti A, Hallin M, Struelens MJ, Edwards G, Böse R, Nübel U, Witte W.

PLoS One. 2014 Feb 4;9(2):e88083. doi: 10.1371/journal.pone.0088083. eCollection 2014.

26.

Evolution of methicillin-resistant Staphylococcus aureus towards increasing resistance.

Strommenger B, Bartels MD, Kurt K, Layer F, Rohde SM, Boye K, Westh H, Witte W, De Lencastre H, Nübel U.

J Antimicrob Chemother. 2014 Mar;69(3):616-22. doi: 10.1093/jac/dkt413. Epub 2013 Oct 22.

PMID:
24150844
27.

Wall teichoic acid structure governs horizontal gene transfer between major bacterial pathogens.

Winstel V, Liang C, Sanchez-Carballo P, Steglich M, Munar M, Bröker BM, Penadés JR, Nübel U, Holst O, Dandekar T, Peschel A, Xia G.

Nat Commun. 2013;4:2345. doi: 10.1038/ncomms3345.

28.

Staphylococcus aureus toxins--their functions and genetics.

Grumann D, Nübel U, Bröker BM.

Infect Genet Evol. 2014 Jan;21:583-92. doi: 10.1016/j.meegid.2013.03.013. Epub 2013 Mar 26. Review.

PMID:
23541411
29.

Subpopulations of Staphylococcus aureus clonal complex 121 are associated with distinct clinical entities.

Kurt K, Rasigade JP, Laurent F, Goering RV, Žemličková H, Machova I, Struelens MJ, Zautner AE, Holtfreter S, Bröker B, Ritchie S, Reaksmey S, Limmathurotsakul D, Peacock SJ, Cuny C, Layer F, Witte W, Nübel U.

PLoS One. 2013;8(3):e58155. doi: 10.1371/journal.pone.0058155. Epub 2013 Mar 7.

30.

Whole genome sequencing versus traditional genotyping for investigation of a Mycobacterium tuberculosis outbreak: a longitudinal molecular epidemiological study.

Roetzer A, Diel R, Kohl TA, Rückert C, Nübel U, Blom J, Wirth T, Jaenicke S, Schuback S, Rüsch-Gerdes S, Supply P, Kalinowski J, Niemann S.

PLoS Med. 2013;10(2):e1001387. doi: 10.1371/journal.pmed.1001387. Epub 2013 Feb 12.

31.

MRSA transmission on a neonatal intensive care unit: epidemiological and genome-based phylogenetic analyses.

Nübel U, Nachtnebel M, Falkenhorst G, Benzler J, Hecht J, Kube M, Bröcker F, Moelling K, Bührer C, Gastmeier P, Piening B, Behnke M, Dehnert M, Layer F, Witte W, Eckmanns T.

PLoS One. 2013;8(1):e54898. doi: 10.1371/journal.pone.0054898. Epub 2013 Jan 31.

32.

A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic.

Holden MT, Hsu LY, Kurt K, Weinert LA, Mather AE, Harris SR, Strommenger B, Layer F, Witte W, de Lencastre H, Skov R, Westh H, Zemlicková H, Coombs G, Kearns AM, Hill RL, Edgeworth J, Gould I, Gant V, Cooke J, Edwards GF, McAdam PR, Templeton KE, McCann A, Zhou Z, Castillo-Ramírez S, Feil EJ, Hudson LO, Enright MC, Balloux F, Aanensen DM, Spratt BG, Fitzgerald JR, Parkhill J, Achtman M, Bentley SD, Nübel U.

Genome Res. 2013 Apr;23(4):653-64. doi: 10.1101/gr.147710.112. Epub 2013 Jan 8.

33.

High resolution discrimination of clinical Mycobacterium tuberculosis complex strains based on single nucleotide polymorphisms.

Homolka S, Projahn M, Feuerriegel S, Ubben T, Diel R, Nübel U, Niemann S.

PLoS One. 2012;7(7):e39855. doi: 10.1371/journal.pone.0039855. Epub 2012 Jul 2.

34.

Single-nucleotide polymorphism genotyping identifies a locally endemic clone of methicillin-resistant Staphylococcus aureus.

Nübel U, Nitsche A, Layer F, Strommenger B, Witte W.

PLoS One. 2012;7(3):e32698. doi: 10.1371/journal.pone.0032698. Epub 2012 Mar 9.

35.

Evaluation of adding a second marker to overcome Staphylococcus aureus spa typing homoplasies.

Basset P, Nübel U, Witte W, Blanc DS.

J Clin Microbiol. 2012 Apr;50(4):1475-7. doi: 10.1128/JCM.00664-11. Epub 2012 Jan 18.

36.

From types to trees: reconstructing the spatial spread of Staphylococcus aureus based on DNA variation.

Nübel U, Strommenger B, Layer F, Witte W.

Int J Med Microbiol. 2011 Dec;301(8):614-8. doi: 10.1016/j.ijmm.2011.09.007. Epub 2011 Oct 8. Review.

PMID:
21983337
37.

Antibiotic resistance and molecular epidemiology of Staphylococcus aureus in Nigeria.

Shittu AO, Okon K, Adesida S, Oyedara O, Witte W, Strommenger B, Layer F, Nübel U.

BMC Microbiol. 2011 May 5;11:92. doi: 10.1186/1471-2180-11-92.

38.

A timescale for evolution, population expansion, and spatial spread of an emerging clone of methicillin-resistant Staphylococcus aureus.

Nübel U, Dordel J, Kurt K, Strommenger B, Westh H, Shukla SK, Zemlicková H, Leblois R, Wirth T, Jombart T, Balloux F, Witte W.

PLoS Pathog. 2010 Apr 8;6(4):e1000855. doi: 10.1371/journal.ppat.1000855.

39.

Fluoroquinolone resistance and Clostridium difficile, Germany.

Zaiss NH, Witte W, Nübel U.

Emerg Infect Dis. 2010 Apr;16(4):675-7. doi: 10.3201/eid1604.090859.

40.

Emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different animal species.

Cuny C, Friedrich A, Kozytska S, Layer F, Nübel U, Ohlsen K, Strommenger B, Walther B, Wieler L, Witte W.

Int J Med Microbiol. 2010 Feb;300(2-3):109-17. doi: 10.1016/j.ijmm.2009.11.002. Epub 2009 Dec 16. Review.

PMID:
20005777
41.

Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus.

Lowder BV, Guinane CM, Ben Zakour NL, Weinert LA, Conway-Morris A, Cartwright RA, Simpson AJ, Rambaut A, Nübel U, Fitzgerald JR.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19545-50. doi: 10.1073/pnas.0909285106. Epub 2009 Nov 2.

42.

Characterization of meticillin-resistant Staphylococcus aureus isolates from hospitals in KwaZulu-Natal province, Republic of South Africa.

Shittu A, Nübel U, Udo E, Lin J, Gaogakwe S.

J Med Microbiol. 2009 Sep;58(Pt 9):1219-26. doi: 10.1099/jmm.0.011452-0. Epub 2009 Jun 15.

PMID:
19528149
43.

Multiplexed genotyping of methicillin-resistant Staphylococcus aureus isolates by use of padlock probes and tag microarrays.

Kurt K, Alderborn A, Nilsson M, Strommenger B, Witte W, Nübel U.

J Clin Microbiol. 2009 Mar;47(3):577-85. doi: 10.1128/JCM.01347-08. Epub 2009 Jan 21.

44.

Clinical and microbiological features of melioidosis in northern Vietnam.

Phuong DM, Trung TT, Breitbach K, Tuan NQ, Nübel U, Flunker G, Khang DD, Quang NX, Steinmetz I.

Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S30-6. doi: 10.1016/S0035-9203(08)70009-9.

PMID:
19121682
45.

Typing Clostridium difficile strains based on tandem repeat sequences.

Zaiss NH, Rupnik M, Kuijper EJ, Harmanus C, Michielsen D, Janssens K, Nübel U.

BMC Microbiol. 2009 Jan 8;9:6. doi: 10.1186/1471-2180-9-6.

46.

Frequent emergence and limited geographic dispersal of methicillin-resistant Staphylococcus aureus.

Nübel U, Roumagnac P, Feldkamp M, Song JH, Ko KS, Huang YC, Coombs G, Ip M, Westh H, Skov R, Struelens MJ, Goering RV, Strommenger B, Weller A, Witte W, Achtman M.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14130-5. doi: 10.1073/pnas.0804178105. Epub 2008 Sep 4.

47.

Emergence and spread of antibiotic-resistant Gram-positive bacterial pathogens.

Witte W, Cuny C, Klare I, Nübel U, Strommenger B, Werner G.

Int J Med Microbiol. 2008 Jul;298(5-6):365-77. doi: 10.1016/j.ijmm.2007.10.005. Epub 2008 Mar 5. Review.

PMID:
18325835
48.

spa Typing of Staphylococcus aureus as a frontline tool in epidemiological typing.

Strommenger B, Braulke C, Heuck D, Schmidt C, Pasemann B, Nübel U, Witte W.

J Clin Microbiol. 2008 Feb;46(2):574-81. Epub 2007 Nov 21.

49.

Meticillin-resistant Staphylococcus aureus: occurrence of a new spa type in two acute care hospitals in Austria.

Ruppitsch W, Stöger A, Braun O, Strommenger B, Nübel U, Wewalka G, Allerberger F.

J Hosp Infect. 2007 Dec;67(4):316-22. Epub 2007 Nov 19.

PMID:
18022286
50.

DNA microarray for detection of antibiotic resistance determinants in Bacillus anthracis and closely related Bacillus cereus.

Antwerpen MH, Schellhase M, Ehrentreich-Förster E, Bier F, Witte W, Nübel U.

Mol Cell Probes. 2007 Apr;21(2):152-60. Epub 2006 Oct 18.

PMID:
17118627

Supplemental Content

Support Center