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Items: 17


Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry.

Brummelman J, Haftmann C, Núñez NG, Alvisi G, Mazza EMC, Becher B, Lugli E.

Nat Protoc. 2019 Jul;14(7):1946-1969. doi: 10.1038/s41596-019-0166-2. Epub 2019 Jun 3.


TLR3 Activation of Intratumoral CD103+ Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity.

Roselli E, Araya P, Núñez NG, Gatti G, Graziano F, Sedlik C, Benaroch P, Piaggio E, Maccioni M.

Front Immunol. 2019 Mar 20;10:503. doi: 10.3389/fimmu.2019.00503. eCollection 2019.


The end of omics? High dimensional single cell analysis in precision medicine.

Galli E, Friebel E, Ingelfinger F, Unger S, Núñez NG, Becher B.

Eur J Immunol. 2019 Feb;49(2):212-220. doi: 10.1002/eji.201847758. Epub 2019 Jan 25. Review.


IL2/Anti-IL2 Complex Combined with CTLA-4, But Not PD-1, Blockade Rescues Antitumor NK Cell Function by Regulatory T-cell Modulation.

Caudana P, Núñez NG, De La Rochere P, Pinto A, Denizeau J, Alonso R, Niborski LL, Lantz O, Sedlik C, Piaggio E.

Cancer Immunol Res. 2019 Mar;7(3):443-457. doi: 10.1158/2326-6066.CIR-18-0697. Epub 2019 Jan 16.


Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.

Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B.

Sci Transl Med. 2018 Nov 28;10(469). pii: eaat8410. doi: 10.1126/scitranslmed.aat8410.


IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection.

Tosello Boari J, Araujo Furlan CL, Fiocca Vernengo F, Rodriguez C, Ramello MC, Amezcua Vesely MC, Gorosito Serrán M, Nuñez NG, Richer W, Piaggio E, Montes CL, Gruppi A, Acosta Rodríguez EV.

Front Immunol. 2018 Oct 11;9:2347. doi: 10.3389/fimmu.2018.02347. eCollection 2018.


Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node.

Alonso R, Flament H, Lemoine S, Sedlik C, Bottasso E, Péguillet I, Prémel V, Denizeau J, Salou M, Darbois A, Núñez NG, Salomon B, Gross D, Piaggio E, Lantz O.

Nat Commun. 2018 May 29;9(1):2113. doi: 10.1038/s41467-018-04524-x.


Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma.

Trucco LD, Roselli E, Araya P, Nuñez NG, Mena HA, Bocco JL, Negrotto S, Maccioni M.

PLoS One. 2017 Jun 29;12(6):e0179897. doi: 10.1371/journal.pone.0179897. eCollection 2017.


Phenotype of NK-Like CD8(+) T Cells with Innate Features in Humans and Their Relevance in Cancer Diseases.

Barbarin A, Cayssials E, Jacomet F, Nunez NG, Basbous S, Lefèvre L, Abdallah M, Piccirilli N, Morin B, Lavoue V, Catros V, Piaggio E, Herbelin A, Gombert JM.

Front Immunol. 2017 Mar 27;8:316. doi: 10.3389/fimmu.2017.00316. eCollection 2017.


Loss of immune tolerance to IL-2 in type 1 diabetes.

Pérol L, Lindner JM, Caudana P, Nunez NG, Baeyens A, Valle A, Sedlik C, Loirat D, Boyer O, Créange A, Cohen JL, Rogner UC, Yamanouchi J, Marchant M, Leber XC, Scharenberg M, Gagnerault MC, Mallone R, Battaglia M, Santamaria P, Hartemann A, Traggiai E, Piaggio E.

Nat Commun. 2016 Oct 6;7:13027. doi: 10.1038/ncomms13027.


In Vivo Visualizing the IFN-β Response Required for Tumor Growth Control in a Therapeutic Model of Polyadenylic-Polyuridylic Acid Administration.

Nocera DA, Roselli E, Araya P, Nuñez NG, Lienenklaus S, Jablonska J, Weiss S, Gatti G, Brinkmann MM, Kröger A, Morón G, Maccioni M.

J Immunol. 2016 Mar 15;196(6):2860-9. doi: 10.4049/jimmunol.1501044. Epub 2016 Feb 15.


Aging Impairs the Ability of Conventional Dendritic Cells to Cross-Prime CD8+ T Cells upon Stimulation with a TLR7 Ligand.

Zacca ER, Crespo MI, Acland RP, Roselli E, Núñez NG, Maccioni M, Maletto BA, Pistoresi-Palencia MC, Morón G.

PLoS One. 2015 Oct 16;10(10):e0140672. doi: 10.1371/journal.pone.0140672. eCollection 2015.


Krüppel-like factor 6 interferes with cellular transformation induced by the H-ras oncogene.

Trucco LD, Andreoli V, Núñez NG, Maccioni M, Bocco JL.

FASEB J. 2014 Dec;28(12):5262-76. doi: 10.1096/fj.14-251884. Epub 2014 Sep 11.


Direct effect of dsRNA mimetics on cancer cells induces endogenous IFN-β production capable of improving dendritic cell function.

Gatti G, Nuñez NG, Nocera DA, Dejager L, Libert C, Giraudo C, Maccioni M.

Eur J Immunol. 2013 Jul;43(7):1849-61. doi: 10.1002/eji.201242902. Epub 2013 May 28.


TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface.

Crespo MI, Zacca ER, Núñez NG, Ranocchia RP, Maccioni M, Maletto BA, Pistoresi-Palencia MC, Morón G.

J Immunol. 2013 Feb 1;190(3):948-60. doi: 10.4049/jimmunol.1102725. Epub 2013 Jan 2.


IFNβ produced by TLR4-activated tumor cells is involved in improving the antitumoral immune response.

Núñez NG, Andreani V, Crespo MI, Nocera DA, Breser ML, Morón G, Dejager L, Libert C, Rivero V, Maccioni M.

Cancer Res. 2012 Feb 1;72(3):592-603. doi: 10.1158/0008-5472.CAN-11-0534. Epub 2011 Dec 2.


The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.

Kowaljow V, Marcowycz A, Ansseau E, Conde CB, Sauvage S, Mattéotti C, Arias C, Corona ED, Nuñez NG, Leo O, Wattiez R, Figlewicz D, Laoudj-Chenivesse D, Belayew A, Coppée F, Rosa AL.

Neuromuscul Disord. 2007 Aug;17(8):611-23. Epub 2007 Jun 27.


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