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Best matches for Näär AM[au]:

Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. Hancock ML et al. Cell. (2019)

MicroRNAs in metabolism and metabolic disorders. Rottiers V et al. Nat Rev Mol Cell Biol. (2012)

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis. Wagschal A et al. Nat Med. (2015)

Search results

Items: 48

1.
2.

A lipid-free and insulin-supplemented medium supports De Novo fatty acid synthesis gene activation in melanoma cells.

Wu S, Näär AM.

PLoS One. 2019 Apr 10;14(4):e0215022. doi: 10.1371/journal.pone.0215022. eCollection 2019.

3.

Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression.

Hancock ML, Meyer RC, Mistry M, Khetani RS, Wagschal A, Shin T, Ho Sui SJ, Näär AM, Flanagan JG.

Cell. 2019 Apr 18;177(3):722-736.e22. doi: 10.1016/j.cell.2019.02.030. Epub 2019 Apr 4.

PMID:
30955890
4.

Development of Locked Nucleic Acid Antisense Oligonucleotides Targeting Ebola Viral Proteins and Host Factor Niemann-Pick C1.

Chery J, Petri A, Wagschal A, Lim SY, Cunningham J, Vasudevan S, Kauppinen S, Näär AM.

Nucleic Acid Ther. 2018 Oct;28(5):273-284. doi: 10.1089/nat.2018.0722. Epub 2018 Aug 22.

5.

miR-33: A Metabolic Conundrum.

Näär AM.

Trends Endocrinol Metab. 2018 Oct;29(10):667-668. doi: 10.1016/j.tem.2018.04.004. Epub 2018 Apr 21.

6.

MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains.

Lai L, Azzam KM, Lin WC, Rai P, Lowe JM, Gabor KA, Madenspacher JH, Aloor JJ, Parks JS, Näär AM, Fessler MB.

J Biol Chem. 2016 Sep 9;291(37):19651-60. doi: 10.1074/jbc.M116.723056. Epub 2016 Jul 28.

7.

miRNA regulation of LDL-cholesterol metabolism.

Goedeke L, Wagschal A, Fernández-Hernando C, Näär AM.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt B):2047-2052. doi: 10.1016/j.bbalip.2016.03.007. Epub 2016 Mar 9. Review.

8.

Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H.

Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17.

9.

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.

Wagschal A, Najafi-Shoushtari SH, Wang L, Goedeke L, Sinha S, deLemos AS, Black JC, Ramírez CM, Li Y, Tewhey R, Hatoum I, Shah N, Lu Y, Kristo F, Psychogios N, Vrbanac V, Lu YC, Hla T, de Cabo R, Tsang JS, Schadt E, Sabeti PC, Kathiresan S, Cohen DE, Whetstine J, Chung RT, Fernández-Hernando C, Kaplan LM, Bernards A, Gerszten RE, Näär AM.

Nat Med. 2015 Nov;21(11):1290-7. doi: 10.1038/nm.3980. Epub 2015 Oct 26.

10.

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels.

Goedeke L, Rotllan N, Canfrán-Duque A, Aranda JF, Ramírez CM, Araldi E, Lin CS, Anderson NN, Wagschal A, de Cabo R, Horton JD, Lasunción MA, Näär AM, Suárez Y, Fernández-Hernando C.

Nat Med. 2015 Nov;21(11):1280-9. doi: 10.1038/nm.3949. Epub 2015 Oct 5.

11.

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.

Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, Blasco MA, Hinds PW, Kuperwasser C.

Nat Commun. 2015 Jun 24;6:7505. doi: 10.1038/ncomms8505.

12.

A role for FACT in repopulation of nucleosomes at inducible genes.

Voth WP, Takahata S, Nishikawa JL, Metcalfe BM, Näär AM, Stillman DJ.

PLoS One. 2014 Jan 2;9(1):e84092. doi: 10.1371/journal.pone.0084092. eCollection 2014.

13.

Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR.

Rottiers V, Obad S, Petri A, McGarrah R, Lindholm MW, Black JC, Sinha S, Goody RJ, Lawrence MS, deLemos AS, Hansen HF, Whittaker S, Henry S, Brookes R, Najafi-Shoushtari SH, Chung RT, Whetstine JR, Gerszten RE, Kauppinen S, Näär AM.

Sci Transl Med. 2013 Nov 20;5(212):212ra162. doi: 10.1126/scitranslmed.3006840.

14.

SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.

Toiber D, Erdel F, Bouazoune K, Silberman DM, Zhong L, Mulligan P, Sebastian C, Cosentino C, Martinez-Pastor B, Giacosa S, D'Urso A, Näär AM, Kingston R, Rippe K, Mostoslavsky R.

Mol Cell. 2013 Aug 22;51(4):454-68. doi: 10.1016/j.molcel.2013.06.018. Epub 2013 Aug 1.

15.

Anti-atherosclerosis or No Anti-atherosclerosis: That is the miR-33 question.

Näär AM.

Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):447-8. doi: 10.1161/ATVBAHA.112.301021. No abstract available.

16.

MicroRNAs in metabolism and metabolic disorders.

Rottiers V, Näär AM.

Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):239-50. doi: 10.1038/nrm3313. Review. Erratum in: Nat Rev Mol Cell Biol. 2012 May;13(5). doi:10.1038/nrm3328.

17.

MicroRNAs in metabolism and metabolic diseases.

Rottiers V, Najafi-Shoushtari SH, Kristo F, Gurumurthy S, Zhong L, Li Y, Cohen DE, Gerszten RE, Bardeesy N, Mostoslavsky R, Näär AM.

Cold Spring Harb Symp Quant Biol. 2011;76:225-33. doi: 10.1101/sqb.2011.76.011049. Epub 2011 Dec 12.

18.

A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.

Walker AK, Jacobs RL, Watts JL, Rottiers V, Jiang K, Finnegan DM, Shioda T, Hansen M, Yang F, Niebergall LJ, Vance DE, Tzoneva M, Hart AC, Näär AM.

Cell. 2011 Nov 11;147(4):840-52. doi: 10.1016/j.cell.2011.09.045. Epub 2011 Oct 27.

19.

MiRs with a sweet tooth.

Näär AM.

Cell Metab. 2011 Aug 3;14(2):149-50. doi: 10.1016/j.cmet.2011.07.005.

20.

A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development.

Mulligan P, Yang F, Di Stefano L, Ji JY, Ouyang J, Nishikawa JL, Toiber D, Kulkarni M, Wang Q, Najafi-Shoushtari SH, Mostoslavsky R, Gygi SP, Gill G, Dyson NJ, Näär AM.

Mol Cell. 2011 Jun 10;42(5):689-99. doi: 10.1016/j.molcel.2011.04.020. Epub 2011 May 19.

21.

Structure of the VP16 transactivator target in the Mediator.

Milbradt AG, Kulkarni M, Yi T, Takeuchi K, Sun ZY, Luna RE, Selenko P, Näär AM, Wagner G.

Nat Struct Mol Biol. 2011 Apr;18(4):410-5. doi: 10.1038/nsmb.1999. Epub 2011 Mar 6.

22.

Functional antagonism between histone H3K4 demethylases in vivo.

Di Stefano L, Walker JA, Burgio G, Corona DF, Mulligan P, Näär AM, Dyson NJ.

Genes Dev. 2011 Jan 1;25(1):17-28. doi: 10.1101/gad.1983711.

23.

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM.

Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210.

24.

Differential roles of transcriptional mediator subunits in regulation of multidrug resistance gene expression in Saccharomyces cerevisiae.

Shahi P, Gulshan K, Näär AM, Moye-Rowley WS.

Mol Biol Cell. 2010 Jul 15;21(14):2469-82. doi: 10.1091/mbc.E09-10-0899. Epub 2010 May 26.

25.

MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis.

Najafi-Shoushtari SH, Kristo F, Li Y, Shioda T, Cohen DE, Gerszten RE, Näär AM.

Science. 2010 Jun 18;328(5985):1566-9. doi: 10.1126/science.1189123. Epub 2010 May 13.

26.

Nuclear receptor-like transcription factors in fungi.

Näär AM, Thakur JK.

Genes Dev. 2009 Feb 15;23(4):419-32. doi: 10.1101/gad.1743009. Review.

27.

Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p.

Thakur JK, Arthanari H, Yang F, Chau KH, Wagner G, Näär AM.

J Biol Chem. 2009 Feb 13;284(7):4422-8. doi: 10.1074/jbc.M808263200. Epub 2008 Dec 4.

28.

E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8.

Morris EJ, Ji JY, Yang F, Di Stefano L, Herr A, Moon NS, Kwon EJ, Haigis KM, Näär AM, Dyson NJ.

Nature. 2008 Sep 25;455(7212):552-6. doi: 10.1038/nature07310. Epub 2008 Sep 14.

29.

A nuclear receptor-like pathway regulating multidrug resistance in fungi.

Thakur JK, Arthanari H, Yang F, Pan SJ, Fan X, Breger J, Frueh DP, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS, Cormack BP, Wagner G, Näär AM.

Nature. 2008 Apr 3;452(7187):604-9. doi: 10.1038/nature06836.

PMID:
18385733
30.

Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation.

Beyer KS, Beauchamp RL, Lee MF, Gusella JF, Näär AM, Ramesh V.

J Biol Chem. 2007 Nov 2;282(44):32152-7. Epub 2007 Sep 11.

31.

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.

Binné UK, Classon MK, Dick FA, Wei W, Rape M, Kaelin WG Jr, Näär AM, Dyson NJ.

Nat Cell Biol. 2007 Feb;9(2):225-32. Epub 2006 Dec 24. Erratum in: Nat Cell Biol. 2007 Mar;9(3):353.

PMID:
17187060
32.

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

Yang F, Vought BW, Satterlee JS, Walker AK, Jim Sun ZY, Watts JL, DeBeaumont R, Saito RM, Hyberts SG, Yang S, Macol C, Iyer L, Tjian R, van den Heuvel S, Hart AC, Wagner G, Näär AM.

Nature. 2006 Aug 10;442(7103):700-4. Epub 2006 Jun 21.

PMID:
16799563
33.

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R.

Cell. 2005 Oct 21;123(2):265-76.

34.

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, Fukasawa T, Gustafsson CM, Han M, He X, Herman PK, Hinnebusch AG, Holmberg S, Holstege FC, Jaehning JA, Kim YJ, Kuras L, Leutz A, Lis JT, Meisterernest M, Naar AM, Nasmyth K, Parvin JD, Ptashne M, Reinberg D, Ronne H, Sadowski I, Sakurai H, Sipiczki M, Sternberg PW, Stillman DJ, Strich R, Struhl K, Svejstrup JQ, Tuck S, Winston F, Roeder RG, Kornberg RD.

Mol Cell. 2004 Jun 4;14(5):553-7. No abstract available.

35.
36.

A component of the ARC/Mediator complex required for TGF beta/Nodal signalling.

Kato Y, Habas R, Katsuyama Y, Näär AM, He X.

Nature. 2002 Aug 8;418(6898):641-6. Epub 2002 Jul 24.

PMID:
12167862
37.

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation.

Näär AM, Taatjes DJ, Zhai W, Nogales E, Tjian R.

Genes Dev. 2002 Jun 1;16(11):1339-44.

38.

Structure, function, and activator-induced conformations of the CRSP coactivator.

Taatjes DJ, Näär AM, Andel F 3rd, Nogales E, Tjian R.

Science. 2002 Feb 8;295(5557):1058-62.

39.

Transcriptional coactivator complexes.

Näär AM, Lemon BD, Tjian R.

Annu Rev Biochem. 2001;70:475-501. Review.

PMID:
11395415
40.

Cofactor requirements for transcriptional activation by Sp1.

Näär AM, Ryu S, Tjian R.

Cold Spring Harb Symp Quant Biol. 1998;63:189-99. Review. No abstract available.

PMID:
10384283
41.

Composite co-activator ARC mediates chromatin-directed transcriptional activation.

Näär AM, Beaurang PA, Zhou S, Abraham S, Solomon W, Tjian R.

Nature. 1999 Apr 29;398(6730):828-32.

PMID:
10235267
42.

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Näär AM, Erdjument-Bromage H, Tempst P, Freedman LP.

Nature. 1999 Apr 29;398(6730):824-8.

PMID:
10235266
43.

Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro.

Näär AM, Beaurang PA, Robinson KM, Oliner JD, Avizonis D, Scheek S, Zwicker J, Kadonaga JT, Tjian R.

Genes Dev. 1998 Oct 1;12(19):3020-31.

44.

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor.

Hörlein AJ, Näär AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, Ryan A, Kamei Y, Söderström M, Glass CK, et al.

Nature. 1995 Oct 5;377(6548):397-404.

PMID:
7566114
45.
46.

Transcriptional regulation by the nuclear receptor superfamily.

Yu VC, Näär AM, Rosenfeld MG.

Curr Opin Biotechnol. 1992 Dec;3(6):597-602. Review.

PMID:
1369415
47.

RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements.

Yu VC, Delsert C, Andersen B, Holloway JM, Devary OV, Näär AM, Kim SY, Boutin JM, Glass CK, Rosenfeld MG.

Cell. 1991 Dec 20;67(6):1251-66.

PMID:
1662118
48.

The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors.

Näär AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG.

Cell. 1991 Jun 28;65(7):1267-79.

PMID:
1648451

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