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2002 1
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2013 3
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Page 1
MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.
Zhang Z, Zhu J, Huang Y, Li W, Cheng H. Zhang Z, et al. Diagn Pathol. 2018 Nov 3;13(1):85. doi: 10.1186/s13000-018-0763-3. Diagn Pathol. 2018. PMID: 30390677 Free PMC article.
METHODS: We firstly identified the expression and prognostic values of MYO18B in HCC using TCGA cohort and our clinical data. Then, MYO18B knockdown by RNA inference was implemented to investigate the effects of MYO18B on HCC cells. ...MYO18B might be …
METHODS: We firstly identified the expression and prognostic values of MYO18B in HCC using TCGA cohort and our clinical data. Then, …
Myo18b is essential for sarcomere assembly in fast skeletal muscle.
Berger J, Berger S, Li M, Currie PD. Berger J, et al. Hum Mol Genet. 2017 Mar 15;26(6):1146-1156. doi: 10.1093/hmg/ddx025. Hum Mol Genet. 2017. PMID: 28104788
To analyze the role of myosin XVIIIB in skeletal muscle disease, zebrafish mutants for myo18b were generated. Full loss of myo18b function results in a complete lack of sarcomeric structure, revealing a highly surprising and essential role for myo18b in sarco …
To analyze the role of myosin XVIIIB in skeletal muscle disease, zebrafish mutants for myo18b were generated. Full loss of myo18b
MYO18B interacts with the proteasomal subunit Sug1 and is degraded by the ubiquitin-proteasome pathway.
Inoue T, Kon T, Ajima R, Ohkura R, Tani M, Yokota J, Sutoh K. Inoue T, et al. Biochem Biophys Res Commun. 2006 Apr 14;342(3):829-34. doi: 10.1016/j.bbrc.2006.02.025. Epub 2006 Feb 17. Biochem Biophys Res Commun. 2006. PMID: 16499872
MYO18B is a class XVIIIB unconventional myosin encoded by a candidate tumor suppressor gene. ...Furthermore, proteasome dysfunction by a proteasome inhibitor or siRNA-mediated knock-down of Sug1 caused the up-regulation of MYO18B protein and MYO18B was polyub
MYO18B is a class XVIIIB unconventional myosin encoded by a candidate tumor suppressor gene. ...Furthermore, proteasome dysfunction b
Regulation of MYO18B mRNA by a network of C19MC miRNA-520G, IFN-gamma, CEBPB, p53 and bFGF in hepatocellular carcinoma.
Jinesh GG, Napoli M, Ackerman HD, Raulji PM, Montey N, Flores ER, Brohl AS. Jinesh GG, et al. Sci Rep. 2020 Jul 23;10(1):12371. doi: 10.1038/s41598-020-69179-5. Sci Rep. 2020. PMID: 32704163 Free PMC article.
MYO18B has been proposed to contribute to the progression of hepatocellular carcinoma (HCC). ...Furthermore, miR-520G together with mutant-p53 promotes MYO18B transcription. Conversely, bFGF suppresses MYO18B mRNA irrespective of CEBPB, miR-520G overexpressio
MYO18B has been proposed to contribute to the progression of hepatocellular carcinoma (HCC). ...Furthermore, miR-520G together with m
Myosin XVIII.
Taft MH, Latham SL. Taft MH, et al. Adv Exp Med Biol. 2020;1239:421-438. doi: 10.1007/978-3-030-38062-5_19. Adv Exp Med Biol. 2020. PMID: 32451870 Review.
This is supported by the clear association of myosin-18A (Myo18A) and myosin-18B (Myo18B) dysregulation with diseases such as cancer and various myopathies....
This is supported by the clear association of myosin-18A (Myo18A) and myosin-18B (Myo18B) dysregulation with diseases such as cancer …
MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.
Nishioka M, Kohno T, Tani M, Yanaihara N, Tomizawa Y, Otsuka A, Sasaki S, Kobayashi K, Niki T, Maeshima A, Sekido Y, Minna JD, Sone S, Yokota J. Nishioka M, et al. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12269-74. doi: 10.1073/pnas.192445899. Epub 2002 Sep 3. Proc Natl Acad Sci U S A. 2002. PMID: 12209013 Free PMC article.
MYO18B expression was reduced in 88% (30/34) of NSCLC and 47% (8/17) of SCLC cell lines. ...Furthermore, restoration of MYO18B expression in lung carcinoma cells suppressed anchorage-independent growth. ...
MYO18B expression was reduced in 88% (30/34) of NSCLC and 47% (8/17) of SCLC cell lines. ...Furthermore, restoration of MYO18B
HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growth.
Ajima R, Kajiya K, Inoue T, Tani M, Shiraishi-Yamaguchi Y, Maeda M, Segawa T, Furuichi T, Sutoh K, Yokota J. Ajima R, et al. Biochem Biophys Res Commun. 2007 May 18;356(4):851-6. doi: 10.1016/j.bbrc.2007.03.060. Epub 2007 Mar 19. Biochem Biophys Res Commun. 2007. PMID: 17386922
MYO18B is a class XVIII myosin, cloned as a tumor suppressor gene candidate. To investigate the mechanisms of MYO18B-dependent tumor suppression, MYO18B-interacting proteins were searched for by a yeast two-hybrid screen. ...
MYO18B is a class XVIII myosin, cloned as a tumor suppressor gene candidate. To investigate the mechanisms of MYO18B-dependent
Further delineation of MYO18B-related autosomal recessive Klippel-Feil syndrome with myopathy and facial dysmorphism.
Altuame FD, Haldeman-Englert C, Cupler E, Al Muhaizea MA, Al-Zaidan HI, Hashem M, Alkuraya FS. Altuame FD, et al. Am J Med Genet A. 2021 Feb;185(2):370-376. doi: 10.1002/ajmg.a.61957. Epub 2020 Nov 11. Am J Med Genet A. 2021. PMID: 33179433
Klippel-Feil syndrome 4 (KFS4; MIM# 616549) is an autosomal recessive disorder caused by biallelic pathogenic variants in MYO18B and comprises, in addition to Klippel-Feil anomaly (KFA), nemaline myopathy, facial dysmorphism, and short stature. ...KFA and characteristic dy …
Klippel-Feil syndrome 4 (KFS4; MIM# 616549) is an autosomal recessive disorder caused by biallelic pathogenic variants in MYO18B and …
Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.
Salamon M, Millino C, Raffaello A, Mongillo M, Sandri C, Bean C, Negrisolo E, Pallavicini A, Valle G, Zaccolo M, Schiaffino S, Lanfranchi G. Salamon M, et al. J Mol Biol. 2003 Feb 7;326(1):137-49. doi: 10.1016/s0022-2836(02)01335-9. J Mol Biol. 2003. PMID: 12547197
We have characterized a novel unconventional myosin heavy chain, named MYO18B, that appears to be expressed mainly in human cardiac and skeletal muscles and, at lower levels, in testis. ...In some cases, cardiomyocytes show a partial sarcomeric pattern of MYO18B alt …
We have characterized a novel unconventional myosin heavy chain, named MYO18B, that appears to be expressed mainly in human cardiac a …
59 results