MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.
Nishioka M, Kohno T, Tani M, Yanaihara N, Tomizawa Y, Otsuka A, Sasaki S, Kobayashi K, Niki T, Maeshima A, Sekido Y, Minna JD, Sone S, Yokota J.
Nishioka M, et al.
Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12269-74. doi: 10.1073/pnas.192445899. Epub 2002 Sep 3.
Proc Natl Acad Sci U S A. 2002.
PMID: 12209013
Free PMC article.
MYO18B expression was reduced in 88% (30/34) of NSCLC and 47% (8/17) of SCLC cell lines. ...Furthermore, restoration of MYO18B expression in lung carcinoma cells suppressed anchorage-independent growth. ...
MYO18B expression was reduced in 88% (30/34) of NSCLC and 47% (8/17) of SCLC cell lines. ...Furthermore, restoration of MYO18B …