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Items: 1 to 50 of 81

1.

Hepatic IKK epsilon expression is dispensable for high-fat feeding-induced increases in liver lipid content and alterations in glucose tolerance.

Collier JJ, Batdorf HM, Mendoza TM, Burk DH, Martin TM, Zhang J, Mynatt RL, Burke SJ.

Am J Physiol Endocrinol Metab. 2019 Oct 29. doi: 10.1152/ajpendo.00309.2019. [Epub ahead of print]

PMID:
31661298
2.

The RNA binding protein HuR influences skeletal muscle metabolic flexibility in rodents and humans.

Mynatt RL, Noland RC, Elks CM, Vandanmagsar B, Bayless DS, Stone AC, Ghosh S, Ravussin E, Warfel JD.

Metabolism. 2019 Aug;97:40-49. doi: 10.1016/j.metabol.2019.05.010. Epub 2019 May 23.

PMID:
31129047
3.

Extensive metabolic remodeling after limiting mitochondrial lipid burden is consistent with an improved metabolic health profile.

Ghosh S, Wicks SE, Vandanmagsar B, Mendoza TM, Bayless DS, Salbaum JM, Dearth SP, Campagna SR, Mynatt RL, Noland RC.

J Biol Chem. 2019 Aug 16;294(33):12313-12327. doi: 10.1074/jbc.RA118.006074. Epub 2019 May 16.

4.

Secretin: An Old Hormone with a Burning Secret.

Mynatt RL, Ravussin E.

Cell. 2018 Nov 29;175(6):1459-1460. doi: 10.1016/j.cell.2018.11.008.

PMID:
30500531
5.

Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice.

Stephens JM, Bailey JL, Hang H, Rittell V, Dietrich MA, Mynatt RL, Elks CM.

Obesity (Silver Spring). 2018 Sep;26(9):1439-1447. doi: 10.1002/oby.22254.

6.

NT-PGC-1α deficiency decreases mitochondrial FA oxidation in brown adipose tissue and alters substrate utilization in vivo.

Kim J, Park MS, Ha K, Park C, Lee J, Mynatt RL, Chang JS.

J Lipid Res. 2018 Sep;59(9):1660-1670. doi: 10.1194/jlr.M085647. Epub 2018 Jul 19.

7.

Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restriction.

Reichenbach A, Stark R, Mequinion M, Lockie SH, Lemus MB, Mynatt RL, Luquet S, Andrews ZB.

FASEB J. 2018 Jun 22:fj201800634R. doi: 10.1096/fj.201800634R. [Epub ahead of print]

PMID:
29932868
8.

Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet β-cell de-differentiation.

Burke SJ, Batdorf HM, Burk DH, Martin TM, Mendoza T, Stadler K, Alami W, Karlstad MD, Robson MJ, Blakely RD, Mynatt RL, Collier JJ.

Mol Metab. 2018 Aug;14:95-107. doi: 10.1016/j.molmet.2018.06.003. Epub 2018 Jun 6.

9.

Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice.

Reichenbach A, Mequinion M, Bayliss JA, Lockie SH, Lemus MB, Mynatt RL, Stark R, Andrews ZB.

Endocrinology. 2018 Jun 1;159(6):2473-2483. doi: 10.1210/en.2018-00131.

10.

An Extract of Russian Tarragon Prevents Obesity-Related Ectopic Lipid Accumulation.

Yu Y, Mendoza TM, Ribnicky DM, Poulev A, Noland RC, Mynatt RL, Raskin I, Cefalu WT, Floyd ZE.

Mol Nutr Food Res. 2018 Apr;62(8):e1700856. doi: 10.1002/mnfr.201700856. Epub 2018 Apr 3.

11.

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning.

Reichenbach A, Stark R, Mequinion M, Denis RRG, Goularte JF, Clarke RE, Lockie SH, Lemus MB, Kowalski GM, Bruce CR, Huang C, Schittenhelm RB, Mynatt RL, Oldfield BJ, Watt MJ, Luquet S, Andrews ZB.

Cell Rep. 2018 Feb 13;22(7):1745-1759. doi: 10.1016/j.celrep.2018.01.067.

12.

A low fat diet ameliorates pathology but retains beneficial effects associated with CPT1b knockout in skeletal muscle.

Warfel JD, Vandanmagsar B, Wicks SE, Zhang J, Noland RC, Mynatt RL.

PLoS One. 2017 Dec 14;12(12):e0188850. doi: 10.1371/journal.pone.0188850. eCollection 2017.

13.

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.

Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, Ayala JE, Gardell SJ, Smith SR.

Mol Metab. 2018 Jan;7:1-11. doi: 10.1016/j.molmet.2017.10.012. Epub 2017 Nov 6.

14.

Fenugreek supplementation during high-fat feeding improves specific markers of metabolic health.

Knott EJ, Richard AJ, Mynatt RL, Ribnicky D, Stephens JM, Bruce-Keller A.

Sci Rep. 2017 Oct 6;7(1):12770. doi: 10.1038/s41598-017-12846-x.

15.

Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet.

Pepping JK, Vandanmagsar B, Fernandez-Kim SO, Zhang J, Mynatt RL, Bruce-Keller AJ.

PLoS One. 2017 Aug 3;12(8):e0181500. doi: 10.1371/journal.pone.0181500. eCollection 2017.

16.

Diet-induced adipose tissue expansion is mitigated in mice with a targeted inactivation of mesoderm specific transcript (Mest).

Anunciado-Koza RP, Manuel J, Mynatt RL, Zhang J, Kozak LP, Koza RA.

PLoS One. 2017 Jun 22;12(6):e0179879. doi: 10.1371/journal.pone.0179879. eCollection 2017.

17.

Examination of carnitine palmitoyltransferase 1 abundance in white adipose tissue: implications in obesity research.

Warfel JD, Vandanmagsar B, Dubuisson OS, Hodgeson SM, Elks CM, Ravussin E, Mynatt RL.

Am J Physiol Regul Integr Comp Physiol. 2017 May 1;312(5):R816-R820. doi: 10.1152/ajpregu.00520.2016. Epub 2017 Mar 22.

18.

Loss of Oncostatin M Signaling in Adipocytes Induces Insulin Resistance and Adipose Tissue Inflammation in Vivo.

Elks CM, Zhao P, Grant RW, Hang H, Bailey JL, Burk DH, McNulty MA, Mynatt RL, Stephens JM.

J Biol Chem. 2016 Aug 12;291(33):17066-76. doi: 10.1074/jbc.M116.739110. Epub 2016 Jun 20.

19.

Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle.

Vandanmagsar B, Warfel JD, Wicks SE, Ghosh S, Salbaum JM, Burk D, Dubuisson OS, Mendoza TM, Zhang J, Noland RC, Mynatt RL.

Cell Rep. 2016 May 24;15(8):1686-99. doi: 10.1016/j.celrep.2016.04.057. Epub 2016 May 12.

20.

Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver.

Ghosh S, Kruger C, Wicks S, Simon J, Kumar KG, Johnson WD, Mynatt RL, Noland RC, Richards BK.

Nutr Metab (Lond). 2016 Mar 1;13:17. doi: 10.1186/s12986-016-0075-0. eCollection 2016.

21.

Inactivation of adipose angiotensinogen reduces adipose tissue macrophages and increases metabolic activity.

LeMieux MJ, Ramalingam L, Mynatt RL, Kalupahana NS, Kim JH, Moustaïd-Moussa N.

Obesity (Silver Spring). 2016 Feb;24(2):359-67. doi: 10.1002/oby.21352. Epub 2015 Dec 25.

22.

The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation.

Kilroy G, Carter LE, Newman S, Burk DH, Manuel J, Möller A, Bowtell DD, Mynatt RL, Ghosh S, Floyd ZE.

Obesity (Silver Spring). 2015 Nov;23(11):2223-32. doi: 10.1002/oby.21220. Epub 2015 Sep 18.

23.

Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding.

McMillan RP, Wu Y, Voelker K, Fundaro G, Kavanaugh J, Stevens JR, Shabrokh E, Ali M, Harvey M, Anderson AS, Boutagy NE, Mynatt RL, Frisard MI, Hulver MW.

Am J Physiol Regul Integr Comp Physiol. 2015 Aug 1;309(3):R304-13. doi: 10.1152/ajpregu.00139.2015. Epub 2015 Jun 17.

24.

Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism.

Wicks SE, Vandanmagsar B, Haynie KR, Fuller SE, Warfel JD, Stephens JM, Wang M, Han X, Zhang J, Noland RC, Mynatt RL.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3300-9. doi: 10.1073/pnas.1418560112. Epub 2015 Jun 8.

25.

UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity.

Wanders D, Burk DH, Cortez CC, Van NT, Stone KP, Baker M, Mendoza T, Mynatt RL, Gettys TW.

FASEB J. 2015 Jun;29(6):2603-15. doi: 10.1096/fj.14-270348. Epub 2015 Mar 5.

26.

Artemisia supplementation differentially affects the mucosal and luminal ileal microbiota of diet-induced obese mice.

Wicks S, Taylor CM, Luo M, Blanchard E 4th, Ribnicky DM, Cefalu WT, Mynatt RL, Welsh DA.

Nutrition. 2014 Jul-Aug;30(7-8 Suppl):S26-30. doi: 10.1016/j.nut.2014.02.007. Epub 2014 Feb 26.

27.

Effects of Artemisia species on de novo lipogenesis in vivo.

Rood JC, Schwarz JM, Gettys T, Mynatt RL, Mendoza T, Johnson WD, Cefalu WT.

Nutrition. 2014 Jul-Aug;30(7-8 Suppl):S17-20. doi: 10.1016/j.nut.2014.03.029. Epub 2014 Apr 18.

28.

Artemisia dracunculus L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture.

Vandanmagsar B, Haynie KR, Wicks SE, Bermudez EM, Mendoza TM, Ribnicky D, Cefalu WT, Mynatt RL.

Diabetes Obes Metab. 2014 Aug;16(8):728-38. doi: 10.1111/dom.12274. Epub 2014 Mar 10.

29.

Inhibition of carnitine palymitoyltransferase1b induces cardiac hypertrophy and mortality in mice.

Haynie KR, Vandanmagsar B, Wicks SE, Zhang J, Mynatt RL.

Diabetes Obes Metab. 2014 Aug;16(8):757-60. doi: 10.1111/dom.12248. Epub 2014 Jan 16.

30.

Brain transcriptional responses to high-fat diet in Acads-deficient mice reveal energy sensing pathways.

Kruger C, Kumar KG, Mynatt RL, Volaufova J, Richards BK.

PLoS One. 2012;7(8):e41709. doi: 10.1371/journal.pone.0041709. Epub 2012 Aug 22.

31.

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.

Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Bajpeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL.

Cell Metab. 2012 May 2;15(5):764-77. doi: 10.1016/j.cmet.2012.04.005.

32.

Adropin deficiency is associated with increased adiposity and insulin resistance.

Ganesh Kumar K, Zhang J, Gao S, Rossi J, McGuinness OP, Halem HH, Culler MD, Mynatt RL, Butler AA.

Obesity (Silver Spring). 2012 Jul;20(7):1394-402. doi: 10.1038/oby.2012.31. Epub 2012 Feb 9.

33.

Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis.

Begriche K, Levasseur PR, Zhang J, Rossi J, Skorupa D, Solt LA, Young B, Burris TP, Marks DL, Mynatt RL, Butler AA.

J Biol Chem. 2011 Nov 25;286(47):40771-81. doi: 10.1074/jbc.M111.278374. Epub 2011 Oct 7.

34.

Membrane microenvironment regulation of carnitine palmitoyltranferases I and II.

Kashfi K, Mynatt RL, Park EA, Cook GA.

Biochem Soc Trans. 2011 Jun;39(3):833-7. doi: 10.1042/BST0390833.

PMID:
21599656
35.

Inactivation of the mitochondrial carrier SLC25A25 (ATP-Mg2+/Pi transporter) reduces physical endurance and metabolic efficiency in mice.

Anunciado-Koza RP, Zhang J, Ukropec J, Bajpeyi S, Koza RA, Rogers RC, Cefalu WT, Mynatt RL, Kozak LP.

J Biol Chem. 2011 Apr 1;286(13):11659-71. doi: 10.1074/jbc.M110.203000. Epub 2011 Feb 4.

36.

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance.

Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, Dixit VD.

Nat Med. 2011 Feb;17(2):179-88. doi: 10.1038/nm.2279. Epub 2011 Jan 9.

37.

Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance.

Yang H, Youm YH, Vandanmagsar B, Ravussin A, Gimble JM, Greenway F, Stephens JM, Mynatt RL, Dixit VD.

J Immunol. 2010 Aug 1;185(3):1836-45. doi: 10.4049/jimmunol.1000021. Epub 2010 Jun 25.

38.

Carnitine and type 2 diabetes.

Mynatt RL.

Diabetes Metab Res Rev. 2009 Sep;25 Suppl 1:S45-9. doi: 10.1002/dmrr.987. Review.

39.

Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism.

Kumar KG, Trevaskis JL, Lam DD, Sutton GM, Koza RA, Chouljenko VN, Kousoulas KG, Rogers PM, Kesterson RA, Thearle M, Ferrante AW Jr, Mynatt RL, Burris TP, Dong JZ, Halem HA, Culler MD, Heisler LK, Stephens JM, Butler AA.

Cell Metab. 2008 Dec;8(6):468-81. doi: 10.1016/j.cmet.2008.10.011.

40.

Neuropoietin attenuates adipogenesis and induces insulin resistance in adipocytes.

White UA, Stewart WC, Mynatt RL, Stephens JM.

J Biol Chem. 2008 Aug 15;283(33):22505-12. doi: 10.1074/jbc.M710462200. Epub 2008 Jun 18.

41.

Induction of circadian gene expression in human subcutaneous adipose-derived stem cells.

Wu X, Zvonic S, Floyd ZE, Kilroy G, Goh BC, Hernandez TL, Eckel RH, Mynatt RL, Gimble JM.

Obesity (Silver Spring). 2007 Nov;15(11):2560-70.

42.

Circadian rhythms and the regulation of metabolic tissue function and energy homeostasis.

Zvonic S, Floyd ZE, Mynatt RL, Gimble JM.

Obesity (Silver Spring). 2007 Mar;15(3):539-43. Review.

43.

Carnitine revisited: potential use as adjunctive treatment in diabetes.

Power RA, Hulver MW, Zhang JY, Dubois J, Marchand RM, Ilkayeva O, Muoio DM, Mynatt RL.

Diabetologia. 2007 Apr;50(4):824-32. Epub 2007 Feb 20.

44.

Secreted proteins and genes in fetal and neonatal pig adipose tissue and stromal-vascular cells.

Hausman GJ, Poulos SP, Richardson RL, Barb CR, Andacht T, Kirk HC, Mynatt RL.

J Anim Sci. 2006 Jul;84(7):1666-81.

PMID:
16775050
45.

Characterization of peripheral circadian clocks in adipose tissues.

Zvonic S, Ptitsyn AA, Conrad SA, Scott LK, Floyd ZE, Kilroy G, Wu X, Goh BC, Mynatt RL, Gimble JM.

Diabetes. 2006 Apr;55(4):962-70.

46.

Circadian clocks are resounding in peripheral tissues.

Ptitsyn AA, Zvonic S, Conrad SA, Scott LK, Mynatt RL, Gimble JM.

PLoS Comput Biol. 2006 Mar;2(3):e16. Epub 2006 Mar 10.

47.

Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin.

Zhang Y, Kilroy GE, Henagan TM, Prpic-Uhing V, Richards WG, Bannon AW, Mynatt RL, Gettys TW.

FASEB J. 2005 Sep;19(11):1482-91.

PMID:
16126916
48.

Cross-talk among gp130 cytokines in adipocytes.

Zvonic S, Baugh JE Jr, Arbour-Reily P, Mynatt RL, Stephens JM.

J Biol Chem. 2005 Oct 7;280(40):33856-63. Epub 2005 Aug 11.

49.

Mesenchymal stem cells from the outer ear: a novel adult stem cell model system for the study of adipogenesis.

Rim JS, Mynatt RL, Gawronska-Kozak B.

FASEB J. 2005 Jul;19(9):1205-7. Epub 2005 Apr 27.

PMID:
15857881
50.

Differential RNA expression of hepatic tissue in lean and obese mice after LPS-induced systemic inflammation.

Scott LK, Vachharajani V, Minagar A, Mynatt RL, Conrad SA.

Front Biosci. 2005 May 1;10:1828-34.

PMID:
15769670

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