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Genome-wide association studies in apple reveal loci of large effect controlling apple polyphenols.

McClure KA, Gong Y, Song J, Vinqvist-Tymchuk M, Campbell Palmer L, Fan L, Burgher-MacLellan K, Zhang Z, Celton JM, Forney CF, Migicovsky Z, Myles S.

Hortic Res. 2019 Sep 7;6:107. doi: 10.1038/s41438-019-0190-y. eCollection 2019.


Genome-Wide Association Studies in Apple Reveal Loci for Aroma Volatiles, Sugar Composition, and Harvest Date.

Larsen B, Migicovsky Z, Jeppesen AA, Gardner KM, Toldam-Andersen TB, Myles S, Ørgaard M, Petersen MA, Pedersen C.

Plant Genome. 2019 Jun;12(2). doi: 10.3835/plantgenome2018.12.0104.


Apple whole genome sequences: recent advances and new prospects.

Peace CP, Bianco L, Troggio M, van de Weg E, Howard NP, Cornille A, Durel CE, Myles S, Migicovsky Z, Schaffer RJ, Costes E, Fazio G, Yamane H, van Nocker S, Gottschalk C, Costa F, Chagné D, Zhang X, Patocchi A, Gardiner SE, Hardner C, Kumar S, Laurens F, Bucher E, Main D, Jung S, Vanderzande S.

Hortic Res. 2019 Apr 5;6:59. doi: 10.1038/s41438-019-0141-7. eCollection 2019. Review.


Population structure, relatedness and ploidy levels in an apple gene bank revealed through genotyping-by-sequencing.

Larsen B, Gardner K, Pedersen C, Ørgaard M, Migicovsky Z, Myles S, Toldam-Andersen TB.

PLoS One. 2018 Aug 15;13(8):e0201889. doi: 10.1371/journal.pone.0201889. eCollection 2018.


Topological Data Analysis as a Morphometric Method: Using Persistent Homology to Demarcate a Leaf Morphospace.

Li M, An H, Angelovici R, Bagaza C, Batushansky A, Clark L, Coneva V, Donoghue MJ, Edwards E, Fajardo D, Fang H, Frank MH, Gallaher T, Gebken S, Hill T, Jansky S, Kaur B, Klahs PC, Klein LL, Kuraparthy V, Londo J, Migicovsky Z, Miller A, Mohn R, Myles S, Otoni WC, Pires JC, Rieffer E, Schmerler S, Spriggs E, Topp CN, Van Deynze A, Zhang K, Zhu L, Zink BM, Chitwood DH.

Front Plant Sci. 2018 Apr 25;9:553. doi: 10.3389/fpls.2018.00553. eCollection 2018.


Variable Effects of C-Terminal Fusions on FLS2 Function: Not All Epitope Tags Are Created Equal.

Hurst CH, Turnbull D, Myles SM, Leslie K, Keinath NF, Hemsley PA.

Plant Physiol. 2018 Jun;177(2):522-531. doi: 10.1104/pp.17.01700. Epub 2018 Apr 23.


Prediction of Cacao (Theobroma cacao) Resistance to Moniliophthora spp. Diseases via Genome-Wide Association Analysis and Genomic Selection.

McElroy MS, Navarro AJR, Mustiga G, Stack C, Gezan S, Peña G, Sarabia W, Saquicela D, Sotomayor I, Douglas GM, Migicovsky Z, Amores F, Tarqui O, Myles S, Motamayor JC.

Front Plant Sci. 2018 Mar 20;9:343. doi: 10.3389/fpls.2018.00343. eCollection 2018.


A Genome-Wide Association Study of Apple Quality and Scab Resistance.

McClure KA, Gardner KM, Douglas GM, Song J, Forney CF, DeLong J, Fan L, Du L, Toivonen PMA, Somers DJ, Rajcan I, Myles S.

Plant Genome. 2018 Mar;11(1). doi: 10.3835/plantgenome2017.08.0075.


Morphometrics Reveals Complex and Heritable Apple Leaf Shapes.

Migicovsky Z, Li M, Chitwood DH, Myles S.

Front Plant Sci. 2018 Jan 4;8:2185. doi: 10.3389/fpls.2017.02185. eCollection 2017.


A Multicenter Investigation of Factors Influencing Women's Participation in Clinical Trials.

Myles S, Tocci C, Falk M, Lynch S, Torres C, Brown B, Leopanto Firman B, Lake M, Maser CA, Onativia A, Obermeier EM, Macfarlan J, Wapner R, Smulian JC, Kurt A.

J Womens Health (Larchmt). 2018 Mar;27(3):258-270. doi: 10.1089/jwh.2017.6458. Epub 2017 Nov 17.


Patterns of genomic and phenomic diversity in wine and table grapes.

Migicovsky Z, Sawler J, Gardner KM, Aradhya MK, Prins BH, Schwaninger HR, Bustamante CD, Buckler ES, Zhong GY, Brown PJ, Myles S.

Hortic Res. 2017 Aug 2;4:17035. doi: 10.1038/hortres.2017.35. eCollection 2017.


LinkImputeR: user-guided genotype calling and imputation for non-model organisms.

Money D, Migicovsky Z, Gardner K, Myles S.

BMC Genomics. 2017 Jul 10;18(1):523. doi: 10.1186/s12864-017-3873-5.


Exploiting Wild Relatives for Genomics-assisted Breeding of Perennial Crops.

Migicovsky Z, Myles S.

Front Plant Sci. 2017 Apr 4;8:460. doi: 10.3389/fpls.2017.00460. eCollection 2017. Review.



Hailey D, Werkö S, Rosén M, Macpherson K, Myles S, Gallegos Rivero V, Hipólito-Olivares C, Sihvo S, Pwu J, Yang WW, Chen YC, Perez Galán A, Aleman A, Villamil E.

Int J Technol Assess Health Care. 2016 Jan;32(6):376-384. doi: 10.1017/S0266462316000611. Review.


Genome to Phenome Mapping in Apple Using Historical Data.

Migicovsky Z, Gardner KM, Money D, Sawler J, Bloom JS, Moffett P, Chao CT, Schwaninger H, Fazio G, Zhong GY, Myles S.

Plant Genome. 2016 Jul;9(2). doi: 10.3835/plantgenome2015.11.0113.


QTL analysis of soft scald in two apple populations.

McClure KA, Gardner KM, Toivonen PM, Hampson CR, Song J, Forney CF, DeLong J, Rajcan I, Myles S.

Hortic Res. 2016 Sep 14;3:16043. doi: 10.1038/hortres.2016.43. eCollection 2016.


Genomic ancestry estimation quantifies use of wild species in grape breeding.

Migicovsky Z, Sawler J, Money D, Eibach R, Miller AJ, Luby JJ, Jamieson AR, Velasco D, von Kintzel S, Warner J, Wührer W, Brown PJ, Myles S.

BMC Genomics. 2016 Jun 30;17:478. doi: 10.1186/s12864-016-2834-8.


Genetic Analysis of East Asian Grape Cultivars Suggests Hybridization with Wild Vitis.

Goto-Yamamoto N, Sawler J, Myles S.

PLoS One. 2015 Oct 21;10(10):e0140841. doi: 10.1371/journal.pone.0140841. eCollection 2015.


LinkImpute: Fast and Accurate Genotype Imputation for Nonmodel Organisms.

Money D, Gardner K, Migicovsky Z, Schwaninger H, Zhong GY, Myles S.

G3 (Bethesda). 2015 Sep 15;5(11):2383-90. doi: 10.1534/g3.115.021667.


The Genetic Structure of Marijuana and Hemp.

Sawler J, Stout JM, Gardner KM, Hudson D, Vidmar J, Butler L, Page JE, Myles S.

PLoS One. 2015 Aug 26;10(8):e0133292. doi: 10.1371/journal.pone.0133292. eCollection 2015.


Genomics: a potential panacea for the perennial problem.

McClure KA, Sawler J, Gardner KM, Money D, Myles S.

Am J Bot. 2014 Oct;101(10):1780-90. doi: 10.3732/ajb.1400143. Epub 2014 Sep 11.


Fast and cost-effective genetic mapping in apple using next-generation sequencing.

Gardner KM, Brown P, Cooke TF, Cann S, Costa F, Bustamante C, Velasco R, Troggio M, Myles S.

G3 (Bethesda). 2014 Jul 16;4(9):1681-7. doi: 10.1534/g3.114.011023.


The relationship of neuropsychological variables to driving status following holistic neurorehabilitation.

Perumparaichallai RK, Husk KL, Myles SM, Klonoff PS.

Front Neurol. 2014 Apr 23;5:56. doi: 10.3389/fneur.2014.00056. eCollection 2014.


A modern ampelography: a genetic basis for leaf shape and venation patterning in grape.

Chitwood DH, Ranjan A, Martinez CC, Headland LR, Thiem T, Kumar R, Covington MF, Hatcher T, Naylor DT, Zimmerman S, Downs N, Raymundo N, Buckler ES, Maloof JN, Aradhya M, Prins B, Li L, Myles S, Sinha NR.

Plant Physiol. 2014 Jan;164(1):259-72. doi: 10.1104/pp.113.229708. Epub 2013 Nov 27.


Genomics assisted ancestry deconvolution in grape.

Sawler J, Reisch B, Aradhya MK, Prins B, Zhong GY, Schwaninger H, Simon C, Buckler E, Myles S.

PLoS One. 2013 Nov 11;8(11):e80791. doi: 10.1371/journal.pone.0080791. eCollection 2013.


Vitis phylogenomics: hybridization intensities from a SNP array outperform genotype calls.

Miller AJ, Matasci N, Schwaninger H, Aradhya MK, Prins B, Zhong GY, Simon C, Buckler ES, Myles S.

PLoS One. 2013 Nov 13;8(11):e78680. doi: 10.1371/journal.pone.0078680. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/283e5eba-a65d-42a3-a430-6ca0be86147c.


Fundamental misunderstandings.

Rutledge P, Myles S.

Br Dent J. 2013 Sep;215(6):265. doi: 10.1038/sj.bdj.2013.883. No abstract available.


Agriculture: Feeding the future.

McCouch S, Baute GJ, Bradeen J, Bramel P, Bretting PK, Buckler E, Burke JM, Charest D, Cloutier S, Cole G, Dempewolf H, Dingkuhn M, Feuillet C, Gepts P, Grattapaglia D, Guarino L, Jackson S, Knapp S, Langridge P, Lawton-Rauh A, Lijua Q, Lusty C, Michael T, Myles S, Naito K, Nelson RL, Pontarollo R, Richards CM, Rieseberg L, Ross-Ibarra J, Rounsley S, Hamilton RS, Schurr U, Stein N, Tomooka N, van der Knaap E, van Tassel D, Toll J, Valls J, Varshney RK, Ward J, Waugh R, Wenzl P, Zamir D.

Nature. 2013 Jul 4;499(7456):23-4. doi: 10.1038/499023a. No abstract available.


Genetic diversity and population structure assessed by SSR and SNP markers in a large germplasm collection of grape.

Emanuelli F, Lorenzi S, Grzeskowiak L, Catalano V, Stefanini M, Troggio M, Myles S, Martinez-Zapater JM, Zyprian E, Moreira FM, Grando MS.

BMC Plant Biol. 2013 Mar 7;13:39. doi: 10.1186/1471-2229-13-39.


Improving fruit and wine: what does genomics have to offer?

Myles S.

Trends Genet. 2013 Apr;29(4):190-6. doi: 10.1016/j.tig.2013.01.006. Epub 2013 Feb 19.


Involvement of consumers in health technology assessment activities by Inahta agencies.

Hailey D, Werkö S, Bakri R, Cameron A, Göhlen B, Myles S, Pwu J, Yothasamut J.

Int J Technol Assess Health Care. 2013 Jan;29(1):79-83. doi: 10.1017/S026646231200075X. Epub 2012 Dec 10.


Melanesian blond hair is caused by an amino acid change in TYRP1.

Kenny EE, Timpson NJ, Sikora M, Yee MC, Moreno-Estrada A, Eng C, Huntsman S, Burchard EG, Stoneking M, Bustamante CD, Myles S.

Science. 2012 May 4;336(6081):554. doi: 10.1126/science.1217849.


Distinct genetic architectures for male and female inflorescence traits of maize.

Brown PJ, Upadyayula N, Mahone GS, Tian F, Bradbury PJ, Myles S, Holland JB, Flint-Garcia S, McMullen MD, Buckler ES, Rocheford TR.

PLoS Genet. 2011 Nov;7(11):e1002383. doi: 10.1371/journal.pgen.1002383. Epub 2011 Nov 17.


Development of marker sets useful in the early selection of Ren4 powdery mildew resistance and seedlessness for table and raisin grape breeding.

Mahanil S, Ramming D, Cadle-Davidson M, Owens C, Garris A, Myles S, Cadle-Davidson L.

Theor Appl Genet. 2012 Jan;124(1):23-33. doi: 10.1007/s00122-011-1684-7. Epub 2011 Sep 9.


Evaluation of epidural analgesic paste components in lumbar decompressive surgery: a randomized double-blind controlled trial.

Diaz RJ, Myles ST, Hurlbert RJ.

Neurosurgery. 2012 Feb;70(2):414-23; discussion 423-4. doi: 10.1227/NEU.0b013e3182315f05.


Bridging near and remote Oceania: mtDNA and NRY variation in the Solomon Islands.

Delfin F, Myles S, Choi Y, Hughes D, Illek R, van Oven M, Pakendorf B, Kayser M, Stoneking M.

Mol Biol Evol. 2012 Feb;29(2):545-64. doi: 10.1093/molbev/msr186. Epub 2011 Jul 18.


Larger mitochondrial DNA than Y-chromosome differences between matrilocal and patrilocal groups from Sumatra.

Gunnarsdóttir ED, Nandineni MR, Li M, Myles S, Gil D, Pakendorf B, Stoneking M.

Nat Commun. 2011;2:228. doi: 10.1038/ncomms1235. Erratum in: Nat Commun. 2012;3. doi:10.1038/ncomms1401.


Genetic structure and domestication history of the grape.

Myles S, Boyko AR, Owens CL, Brown PJ, Grassi F, Aradhya MK, Prins B, Reynolds A, Chia JM, Ware D, Bustamante CD, Buckler ES.

Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3530-5. doi: 10.1073/pnas.1009363108. Epub 2011 Jan 18.


Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in Tongans.

Myles S, Lea RA, Ohashi J, Chambers GK, Weiss JG, Hardouin E, Engelken J, Macartney-Coxson DP, Eccles DA, Naka I, Kimura R, Inaoka T, Matsumura Y, Stoneking M.

BMC Med Genet. 2011 Jan 18;12:10. doi: 10.1186/1471-2350-12-10.


Abolition of prescription charges in Wales: the impact on medicines use in those who used to pay.

Groves S, Cohen D, Alam MF, Dunstan FD, Routledge PA, Hughes DA, Myles S.

Int J Pharm Pract. 2010 Dec;18(6):332-40. doi: 10.1111/j.2042-7174.2010.00063.x. Epub 2010 Oct 5. Erratum in: Int J Pharm Pract. 2011 Feb;19(1):79.


The Y-chromosome landscape of the Philippines: extensive heterogeneity and varying genetic affinities of Negrito and non-Negrito groups.

Delfin F, Salvador JM, Calacal GC, Perdigon HB, Tabbada KA, Villamor LP, Halos SC, Gunnarsdóttir E, Myles S, Hughes DA, Xu S, Jin L, Lao O, Kayser M, Hurles ME, Stoneking M, De Ungria MC.

Eur J Hum Genet. 2011 Feb;19(2):224-30. doi: 10.1038/ejhg.2010.162. Epub 2010 Sep 29.


First clinical application of an actively reversible direct factor IXa inhibitor as an anticoagulation strategy in patients undergoing percutaneous coronary intervention.

Cohen MG, Purdy DA, Rossi JS, Grinfeld LR, Myles SK, Aberle LH, Greenbaum AB, Fry E, Chan MY, Tonkens RM, Zelenkofske S, Alexander JH, Harrington RA, Rusconi CP, Becker RC.

Circulation. 2010 Aug 10;122(6):614-22. doi: 10.1161/CIRCULATIONAHA.109.927756. Epub 2010 Jul 26.


The effect of aspirin on endothelial progenitor cell biology: preliminary investigation of novel properties.

Lou J, Povsic TJ, Allen JD, Adams SD, Myles S, Starr AZ, Ortel TL, Becker RC.

Thromb Res. 2010 Sep;126(3):e175-9. doi: 10.1016/j.thromres.2009.11.017. Epub 2010 Jul 24.


Abolition of prescription copayments in Wales: an observational study on dispensing rates.

Cohen D, Alam MF, Dunstan FD, Myles S, Hughes DA, Routledge PA.

Value Health. 2010 Aug;13(5):675-80. doi: 10.1111/j.1524-4733.2010.00717.x. Epub 2010 Mar 31.


Accuracy of perceived risk of recurrence among patients with early-stage breast cancer.

Liu Y, Pérez M, Aft RL, Massman K, Robinson E, Myles S, Schootman M, Gillanders WE, Jeffe DB.

Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):675-80. doi: 10.1158/1055-9965.EPI-09-1051. Epub 2010 Feb 16. Erratum in: Cancer Epidemiol Biomarkers Prev. 2010 Jun;19(6):1661.


The relationship of cognitive retraining to neurological patients' driving status: the role of process variables and compensation training.

Klonoff PS, Olson KC, Talley MC, Husk KL, Myles SM, Gehrels JA, Dawson LK.

Brain Inj. 2010 Feb;24(2):63-73. doi: 10.3109/02699050903512863.


Rapid genomic characterization of the genus vitis.

Myles S, Chia JM, Hurwitz B, Simon C, Zhong GY, Buckler E, Ware D.

PLoS One. 2010 Jan 13;5(1):e8219. doi: 10.1371/journal.pone.0008219.


How culture shaped the human genome: bringing genetics and the human sciences together.

Laland KN, Odling-Smee J, Myles S.

Nat Rev Genet. 2010 Feb;11(2):137-48. doi: 10.1038/nrg2734. Review.


Design and rationale of the Evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) trial.

Melloni C, Fier I, Roach J, Kosinski AS, Broderick S, Sigmon K, Myles S, Becker RC, Rao SV; EMINENCE Investigators.

Am Heart J. 2009 Nov;158(5):726-33. doi: 10.1016/j.ahj.2009.08.020. Epub 2009 Sep 30.


Association mapping: critical considerations shift from genotyping to experimental design.

Myles S, Peiffer J, Brown PJ, Ersoz ES, Zhang Z, Costich DE, Buckler ES.

Plant Cell. 2009 Aug;21(8):2194-202. doi: 10.1105/tpc.109.068437. Epub 2009 Aug 4. Review.

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