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Items: 8


TransCon CNP, a Sustained-Release C-Type Natriuretic Peptide Prodrug, a Potentially Safe and Efficacious New Therapeutic Modality for the Treatment of Comorbidities Associated with Fibroblast Growth Factor Receptor 3-Related Skeletal Dysplasias.

Breinholt VM, Rasmussen CE, Mygind PH, Kjelgaard-Hansen M, Faltinger F, Bernhard A, Zettler J, Hersel U.

J Pharmacol Exp Ther. 2019 Sep;370(3):459-471. doi: 10.1124/jpet.119.258251. Epub 2019 Jun 24.


Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.

Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, Jansen A, Nielsen AK, Mygind PH, Raventós DS, Neve S, Ravn B, Bonvin AM, De Maria L, Andersen AS, Gammelgaard LK, Sahl HG, Kristensen HH.

Science. 2010 May 28;328(5982):1168-72. doi: 10.1126/science.1185723.


Antimicrobial peptides effectively kill a broad spectrum of Listeria monocytogenes and Staphylococcus aureus strains independently of origin, sub-type, or virulence factor expression.

Gottlieb CT, Thomsen LE, Ingmer H, Mygind PH, Kristensen HH, Gram L.

BMC Microbiol. 2008 Nov 26;8:205. doi: 10.1186/1471-2180-8-205.


Antimicrobial activity of the recombinant designer host defence peptide P-novispirin G10 in infected full-thickness wounds of porcine skin.

Jacobsen F, Mohammadi-Tabrisi A, Hirsch T, Mittler D, Mygind PH, Sonksen CP, Raventos D, Kristensen HH, Gatermann S, Lehnhardt M, Daigeler A, Steinau HU, Steinstraesser L.

J Antimicrob Chemother. 2007 Mar;59(3):493-8. Epub 2007 Feb 8.


Design of novispirin antimicrobial peptides by quantitative structure-activity relationship.

Taboureau O, Olsen OH, Nielsen JD, Raventos D, Mygind PH, Kristensen HH.

Chem Biol Drug Des. 2006 Jul;68(1):48-57.


Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.

Mygind PH, Fischer RL, Schnorr KM, Hansen MT, Sönksen CP, Ludvigsen S, Raventós D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-Jørgensen SG, Sørensen MV, Christensen BE, Kjaerulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen HH.

Nature. 2005 Oct 13;437(7061):975-80.


Improving on nature's defenses: optimization & high throughput screening of antimicrobial peptides.

Raventós D, Taboureau O, Mygind PH, Nielsen JD, Sonksen CP, Kristensen HH.

Comb Chem High Throughput Screen. 2005 May;8(3):219-33. Review.


Membrane proteins PmpG and PmpH are major constituents of Chlamydia trachomatis L2 outer membrane complex.

Mygind PH, Christiansen G, Roepstorff P, Birkelund S.

FEMS Microbiol Lett. 2000 May 15;186(2):163-9.

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