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Items: 42

1.

Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.

Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN.

Trials. 2019 Jan 14;20(1):48. doi: 10.1186/s13063-018-3155-9.

2.

HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy.

Kelly C, Mwandumba HC, Heyderman RS, Jambo K, Kamng'ona R, Chammudzi M, Sheha I, Peterson I, Rapala A, Mallewa J, Walker AS, Klein N, Khoo S.

J Infect Dis. 2019 Jan 9. doi: 10.1093/infdis/jiz015. [Epub ahead of print]

PMID:
30629187
3.

Aetiology and Risk Factors for Mortality in an Adult Community-Acquired Pneumonia Cohort in Malawi.

Aston SJ, Ho A, Jary H, Huwa J, Mitchell T, Ibitoye S, Greenwood S, Joekes E, Daire A, Mallewa J, Everett D, Nyirenda M, Faragher B, Mwandumba HC, Heyderman RS, Gordon SB.

Am J Respir Crit Care Med. 2019 Jan 9. doi: 10.1164/rccm.201807-1333OC. [Epub ahead of print]

PMID:
30625278
4.

Serum concentration of anti-Cytomegalovirus IgG and ischaemic stroke in patients with advanced HIV infection in Malawi.

Kamtchum-Tatuene J, Al-Bayati Z, Mwandumba HC, Solomon T, Christmas SE, Benjamin LA.

PLoS One. 2018 Nov 27;13(11):e0208040. doi: 10.1371/journal.pone.0208040. eCollection 2018.

5.

AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.

Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN.

Trials. 2018 Nov 23;19(1):649. doi: 10.1186/s13063-018-3026-4. Erratum in: Trials. 2019 Jan 14;20(1):48.

6.

B cell, CD8 + T cell and gamma delta T cell infiltration alters alveolar immune cell homeostasis in HIV-infected Malawian adults.

Mwale A, Hummel A, Mvaya L, Kamng'ona R, Chimbayo E, Phiri J, Malamba R, Kankwatira A, Mwandumba HC, Jambo KC.

Version 2. Wellcome Open Res. 2018 Apr 6 [revised 2018 Jan 1];2:105. doi: 10.12688/wellcomeopenres.12869.3. eCollection 2017.

7.

Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.

Mitsi E, Kamng'ona R, Rylance J, Solórzano C, Jesus Reiné J, Mwandumba HC, Ferreira DM, Jambo KC.

Respir Res. 2018 Apr 18;19(1):66. doi: 10.1186/s12931-018-0777-0.

8.

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy.

Jambo KC, Tembo DL, Kamng'ona AW, Musicha P, Banda DH, Kankwatira AM, Malamba RD, Allain TJ, Heyderman RS, Russell DG, Mwandumba HC.

ERJ Open Res. 2017 Dec 14;3(4). pii: 00097-2017. doi: 10.1183/23120541.00097-2017. eCollection 2017 Oct.

9.

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults.

Peno C, Banda DH, Jambo N, Kankwatira AM, Malamba RD, Allain TJ, Ferreira DM, Heyderman RS, Russell DG, Mwandumba HC, Jambo KC.

J Infect. 2018 Feb;76(2):168-176. doi: 10.1016/j.jinf.2017.10.013. Epub 2017 Nov 29.

10.

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay.

Gupta-Wright A, Tembo D, Jambo KC, Chimbayo E, Mvaya L, Caldwell S, Russell DG, Mwandumba HC.

Front Immunol. 2017 Sep 28;8:1222. doi: 10.3389/fimmu.2017.01222. eCollection 2017.

11.

Challenges of stroke management in resource-limited settings: A case-based reflection.

Gadama YG, Mwangalika G, Kinley LB, Jackson B, Mwandumba HC, Mallewa J, Solomon T, Simister R, Benjamin LA, Vargas MI, Kamtchum-Tatuene J, Phiri T.

Malawi Med J. 2017 Jun;29(2):189-193.

12.

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children.

Nyirenda TS, Nyirenda JT, Tembo DL, Storm J, Dube Q, Msefula CL, Jambo KC, Mwandumba HC, Heyderman RS, Gordon MA, Mandala WL.

Clin Vaccine Immunol. 2017 Jul 5;24(7). pii: e00057-17. doi: 10.1128/CVI.00057-17. Print 2017 Jul.

13.

Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis.

Sloan DJ, McCallum AD, Schipani A, Egan D, Mwandumba HC, Ward SA, Waterhouse D, Banda G, Allain TJ, Owen A, Khoo SH, Davies GR.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00210-17. doi: 10.1128/AAC.00210-17. Print 2017 Jul.

14.

Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study.

McCallum AD, Nyirenda D, Lora W, Khoo SH, Sloan DJ, Mwandumba HC, Desmond N, Davies GR.

PLoS One. 2016 Oct 28;11(10):e0165734. doi: 10.1371/journal.pone.0165734. eCollection 2016.

15.

Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses.

Wilburn KM, Mwandumba HC, Jambo KC, Boliar S, Solouki S, Russell DG, Gludish DW.

Retrovirology. 2016 Aug 11;13(1):55. doi: 10.1186/s12977-016-0289-2.

16.

Unstructured treatment interruption: an important risk factor for arterial stiffness in adult Malawian patients with antiretroviral treatment.

Peterson I, Ming D, Kelly C, Malisita K, Mallewa J, Mwandumba HC, Lalloo DG, Heyderman RS.

AIDS. 2016 Sep 24;30(15):2373-8. doi: 10.1097/QAD.0000000000001198.

PMID:
27428743
17.

High mortality and prevalence of HIV and tuberculosis in adults with chronic cough in Malawi: a cohort study.

Nliwasa M, MacPherson P, Mukaka M, Mdolo A, Mwapasa M, Kaswaswa K, Msefula C, Chipungu G, Mwandumba HC, Corbett EL.

Int J Tuberc Lung Dis. 2016 Feb;20(2):202-10. doi: 10.5588/ijtld.15.0388.

18.

Vitamin D deficiency in Malawian adults with pulmonary tuberculosis: risk factors and treatment outcomes.

Sloan DJ, Mwandumba HC, Kamdolozi M, Shani D, Chisale B, Dutton J, Khoo SH, Allain TJ, Davies GR.

Int J Tuberc Lung Dis. 2015 Aug;19(8):904-11. doi: 10.5588/ijtld.15.0071.

19.

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis.

Mzinza DT, Sloan DJ, Jambo KC, Shani D, Kamdolozi M, Wilkinson KA, Wilkinson RJ, Davies GR, Heyderman RS, Mwandumba HC.

Tuberculosis (Edinb). 2015 Jul;95(4):463-9. doi: 10.1016/j.tube.2015.05.009. Epub 2015 May 28.

20.

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis.

Sloan DJ, Mwandumba HC, Garton NJ, Khoo SH, Butterworth AE, Allain TJ, Heyderman RS, Corbett EL, Barer MR, Davies GR.

Clin Infect Dis. 2015 Jul 1;61(1):1-8. doi: 10.1093/cid/civ195. Epub 2015 Mar 16.

21.

Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria.

Jambo KC, Banda DH, Afran L, Kankwatira AM, Malamba RD, Allain TJ, Gordon SB, Heyderman RS, Russell DG, Mwandumba HC.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):938-47. doi: 10.1164/rccm.201405-0864OC.

22.

Dynamic quantitative assays of phagosomal function.

Podinovskaia M, VanderVen BC, Yates RM, Glennie S, Fullerton D, Mwandumba HC, Russell DG.

Curr Protoc Immunol. 2013 Oct 1;102:Unit 14.34.. doi: 10.1002/0471142735.im1434s102.

23.

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function.

Jambo KC, Banda DH, Kankwatira AM, Sukumar N, Allain TJ, Heyderman RS, Russell DG, Mwandumba HC.

Mucosal Immunol. 2014 Sep;7(5):1116-26. doi: 10.1038/mi.2013.127. Epub 2014 Jan 29.

24.

Optimizing outpatient serial sputum colony counting for studies of tuberculosis treatment in resource-poor settings.

Sloan DJ, Corbett EL, Butterworth AE, Mwandumba HC, Khoo SH, Mdolo A, Shani D, Kamdolozi M, Allen J, Mitchison DA, Coleman DJ, Davies GR.

J Clin Microbiol. 2012 Jul;50(7):2315-20. doi: 10.1128/JCM.00043-12. Epub 2012 May 9.

25.

Voltage-gated, potassium-channel antibody-associated limbic encephalitis presenting as acute psychosis.

Ganguli A, Fitzgerald R, Walker L, Beadsworth M, Mwandumba HC.

J Neuropsychiatry Clin Neurosci. 2011 Spring;23(2):E32-4. doi: 10.1176/appi.neuropsych.23.2.E32. No abstract available.

PMID:
21677219
26.

Insufficient evidence for chest CT scan in TB outbreak investigation.

Joekes E, Davies G, Mwandumba HC, Squire SB.

Chest. 2010 Jul;138(1):234-5. doi: 10.1378/chest.10-0077. No abstract available.

PMID:
20605830
27.

The macrophage marches on its phagosome: dynamic assays of phagosome function.

Russell DG, Vanderven BC, Glennie S, Mwandumba H, Heyderman RS.

Nat Rev Immunol. 2009 Aug;9(8):594-600. doi: 10.1038/nri2591. Epub 2009 Jul 10. Review.

28.

Research capacity development in Malawi: Malcolm Molyneux's role.

Mwandumba HC.

Trans R Soc Trop Med Hyg. 2009 Apr;103 Suppl 1:S19-22. doi: 10.1016/j.trstmh.2009.01.017. Epub 2009 Feb 20.

PMID:
19232656
29.

Hypoadrenalism is not associated with early mortality during tuberculosis treatment in Malawi.

Beadsworth MB, van Oosterhout JJ, Diver MJ, Faragher EB, Shenkin A, Mwandumba HC, Khoo S, O'Dempsey T, Squire SB, Zijlstra EE.

Int J Tuberc Lung Dis. 2008 Mar;12(3):314-8.

PMID:
18284838
30.

The clinical impact of nucleic acid amplification tests on the diagnosis and management of tuberculosis in a British hospital.

Taegtmeyer M, Beeching NJ, Scott J, Seddon K, Jamieson S, Squire SB, Mwandumba HC, Miller AR, Davies PD, Parry CM.

Thorax. 2008 Apr;63(4):317-21. Epub 2007 Nov 16.

PMID:
18024540
31.

Association between sputum smear status and local immune responses at the site of disease in HIV-infected patients with pulmonary tuberculosis.

Mwandumba HC, Bertel Squire S, White SA, Nyirenda MH, Kampondeni SD, Rhoades ER, Zijlstra EE, Molyneux ME, Russell DG.

Tuberculosis (Edinb). 2008 Jan;88(1):58-63. Epub 2007 Oct 3.

PMID:
17913585
32.

Alveolar macrophages from HIV-infected patients with pulmonary tuberculosis retain the capacity to respond to stimulation by lipopolysaccharide.

Mwandumba HC, Squire SB, White SA, Nyirenda MH, Zijlstra EE, Molyneux ME, Russell DG, Rhoades ER.

Microbes Infect. 2007 Jul;9(9):1053-60. Epub 2007 May 16.

PMID:
17644388
33.

Cidofovir treatment of HIV-associated cytomegalovirus polyradiculopathy.

Douthwaite ST, Taegtmeyer M, Stow R, Mwandumba HC, Hart IJ, Beeching NJ.

AIDS. 2006 Feb 28;20(4):632-4. No abstract available.

PMID:
16470133
34.

Mycobacterium tuberculosis resides in nonacidified vacuoles in endocytically competent alveolar macrophages from patients with tuberculosis and HIV infection.

Mwandumba HC, Russell DG, Nyirenda MH, Anderson J, White SA, Molyneux ME, Squire SB.

J Immunol. 2004 Apr 1;172(7):4592-8.

35.

Mycobacterium and the coat of many lipids.

Russell DG, Mwandumba HC, Rhoades EE.

J Cell Biol. 2002 Aug 5;158(3):421-6. Epub 2002 Jul 29. Review.

36.

Patient 1 - A woman with numbness of hands and feet.

Msusa AT, Chibwana C, Mwandumba H.

Malawi Med J. 2002 Apr;14(1):29-30. No abstract available.

37.

Fully intermittent dosing with drugs for treating tuberculosis in adults.

Mwandumba HC, Squire SB.

Cochrane Database Syst Rev. 2001;(4):CD000970. Review.

PMID:
11687088
38.

Fully intermittent dosing with drugs for tuberculosis.

Mwandumba HC, Squire SB.

Cochrane Database Syst Rev. 2000;(4):CD000970. Review. Update in: Cochrane Database Syst Rev. 2001;(4):CD000970.

PMID:
11034692
39.

Fully intermittent dosing with drugs for tuberculosis.

Mwandumba HC, Squire SB.

Cochrane Database Syst Rev. 2000;(2):CD000970. Review. Update in: Cochrane Database Syst Rev. 2000;(4):CD000970.

PMID:
10796561
40.

Pyogenic lung infections: factors for predicting clinical outcome of lung abscess and thoracic empyema.

Mwandumba HC, Beeching NJ.

Curr Opin Pulm Med. 2000 May;6(3):234-9. Review.

PMID:
10782709
41.

Pyogenic lung infections.

Mwandumba HC, Beeching NJ.

Curr Opin Pulm Med. 1999 May;5(3):151-6. Review.

PMID:
10228739
42.

Cryptococcal meningitis in Lilongwe and Blantyre, Malawi.

Maher D, Mwandumba H.

J Infect. 1994 Jan;28(1):59-64.

PMID:
8163834

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