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Items: 27

1.

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis.

Kloprogge F, Workman L, Borrmann S, Tékété M, Lefèvre G, Hamed K, Piola P, Ursing J, Kofoed PE, Mårtensson A, Ngasala B, Björkman A, Ashton M, Friberg Hietala S, Aweeka F, Parikh S, Mwai L, Davis TME, Karunajeewa H, Salman S, Checchi F, Fogg C, Newton PN, Mayxay M, Deloron P, Faucher JF, Nosten F, Ashley EA, McGready R, van Vugt M, Proux S, Price RN, Karbwang J, Ezzet F, Bakshi R, Stepniewska K, White NJ, Guerin PJ, Barnes KI, Tarning J.

PLoS Med. 2018 Jun 12;15(6):e1002579. doi: 10.1371/journal.pmed.1002579. eCollection 2018 Jun.

2.

Response to The routine use of oral steroids in paediatric asthma is not routine.

Smith N, Wang A, Shaw K, Groeneweg G, Goldman RD, Wilkinson B, Jimenez R, Mwai L, Carleton B.

Paediatr Child Health. 2018 May;23(3):239. doi: 10.1093/pch/pxy006. Epub 2018 Apr 7. No abstract available.

3.

Physician and parent barriers to the use of oral corticosteroids for the prevention of paediatric URTI-induced acute asthma exacerbations at home.

Smith N, Smith A, Wang A, Shaw K, Groeneweg G, Goldman RD, Wilkinson B, Jimenez R, Mwai L, Carleton B.

Paediatr Child Health. 2017 Jul;22(4):190-194. doi: 10.1093/pch/pxx047. Epub 2017 May 5.

4.

Antimalarial drugs and the prevalence of mental and neurological manifestations: A systematic review and meta-analysis.

Bitta MA, Kariuki SM, Mwita C, Gwer S, Mwai L, Newton CRJC.

Wellcome Open Res. 2017 Jun 2;2:13. doi: 10.12688/wellcomeopenres.10658.2. eCollection 2017.

6.

Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.

Hoglund RM, Workman L, Edstein MD, Thanh NX, Quang NN, Zongo I, Ouedraogo JB, Borrmann S, Mwai L, Nsanzabana C, Price RN, Dahal P, Sambol NC, Parikh S, Nosten F, Ashley EA, Phyo AP, Lwin KM, McGready R, Day NP, Guerin PJ, White NJ, Barnes KI, Tarning J.

PLoS Med. 2017 Jan 10;14(1):e1002212. doi: 10.1371/journal.pmed.1002212. eCollection 2017 Jan.

7.

The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya.

Ochola-Oyier LI, Okombo J, Mwai L, Kiara SM, Pole L, Tetteh KK, Nzila A, Marsh K.

Antimicrob Agents Chemother. 2015 Mar;59(3):1770-5. doi: 10.1128/AAC.03522-14. Epub 2014 Dec 22.

8.

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.

Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, Mårtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TME, Ménard D, Adam I, Ademowo G, Arze C, Baliraine FN, Berens-Riha N, Björkman A, Borrmann S, Checchi F, Desai M, Dhorda M, Djimdé AA, El-Sayed BB, Eshetu T, Eyase F, Falade C, Faucher JF, Fröberg G, Grivoyannis A, Hamour S, Houzé S, Johnson J, Kamugisha E, Kariuki S, Kiechel JR, Kironde F, Kofoed PE, LeBras J, Malmberg M, Mwai L, Ngasala B, Nosten F, Nsobya SL, Nzila A, Oguike M, Otienoburu SD, Ogutu B, Ouédraogo JB, Piola P, Rombo L, Schramm B, Somé AF, Thwing J, Ursing J, Wong RPM, Zeynudin A, Zongo I, Plowe CV, Sibley CH, Asaq Molecular Marker Study Group.

Am J Trop Med Hyg. 2014 Oct;91(4):833-843. doi: 10.4269/ajtmh.14-0031. Epub 2014 Jul 21. Erratum in: Am J Trop Med Hyg. 2015 May;92(5):1084. Am J Trop Med Hyg. 2019 Mar;100(3):766.

9.

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya.

Wendler JP, Okombo J, Amato R, Miotto O, Kiara SM, Mwai L, Pole L, O'Brien J, Manske M, Alcock D, Drury E, Sanders M, Oyola SO, Malangone C, Jyothi D, Miles A, Rockett KA, MacInnis BL, Marsh K, Bejon P, Nzila A, Kwiatkowski DP.

PLoS One. 2014 May 8;9(5):e96486. doi: 10.1371/journal.pone.0096486. eCollection 2014.

10.

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya.

Borrmann S, Straimer J, Mwai L, Abdi A, Rippert A, Okombo J, Muriithi S, Sasi P, Kortok MM, Lowe B, Campino S, Assefa S, Auburn S, Manske M, Maslen G, Peshu N, Kwiatkowski DP, Marsh K, Nzila A, Clark TG.

Sci Rep. 2013 Nov 25;3:3318. doi: 10.1038/srep03318.

11.

Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.

Okombo J, Abdi AI, Kiara SM, Mwai L, Pole L, Sutherland CJ, Nzila A, Ochola-Oyier LI.

Antimicrob Agents Chemother. 2013 Dec;57(12):6196-204. doi: 10.1128/AAC.01465-13. Epub 2013 Sep 30.

12.

Antimalarial activity of isoquine against Kenyan Plasmodium falciparum clinical isolates and association with polymorphisms in pfcrt and pfmdr1 genes.

Okombo J, Kiara SM, Abdirahman A, Mwai L, Ohuma E, Borrmann S, Nzila A, Ward S.

J Antimicrob Chemother. 2013 Apr;68(4):786-8. doi: 10.1093/jac/dks471. Epub 2012 Nov 20.

PMID:
23169890
13.

Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure.

Mwai L, Diriye A, Masseno V, Muriithi S, Feltwell T, Musyoki J, Lemieux J, Feller A, Mair GR, Marsh K, Newbold C, Nzila A, Carret CK.

PLoS One. 2012;7(2):e31623. doi: 10.1371/journal.pone.0031623. Epub 2012 Feb 27.

14.

Baseline in vitro activities of the antimalarials pyronaridine and methylene blue against Plasmodium falciparum isolates from Kenya.

Okombo J, Kiara SM, Mwai L, Pole L, Ohuma E, Ochola LI, Nzila A.

Antimicrob Agents Chemother. 2012 Feb;56(2):1105-7. doi: 10.1128/AAC.05454-11. Epub 2011 Nov 28.

15.

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast.

Borrmann S, Sasi P, Mwai L, Bashraheil M, Abdallah A, Muriithi S, Frühauf H, Schaub B, Pfeil J, Peshu J, Hanpithakpong W, Rippert A, Juma E, Tsofa B, Mosobo M, Lowe B, Osier F, Fegan G, Lindegårdh N, Nzila A, Peshu N, Mackinnon M, Marsh K.

PLoS One. 2011;6(11):e26005. doi: 10.1371/journal.pone.0026005. Epub 2011 Nov 10.

16.

Antiepileptic properties of quinine: A systematic review.

Mwita C, Mwai L, Newton C.

JBI Libr Syst Rev. 2011;9(48):1999-2022.

PMID:
27819948
17.

In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya.

Okombo J, Kiara SM, Rono J, Mwai L, Pole L, Ohuma E, Borrmann S, Ochola LI, Nzila A.

Antimicrob Agents Chemother. 2010 Aug;54(8):3302-7. doi: 10.1128/AAC.00325-10. Epub 2010 Jun 1.

18.

The role for osmotic agents in children with acute encephalopathies: a systematic review.

Gwer S, Gatakaa H, Mwai L, Idro R, Newton CR.

BMC Pediatr. 2010 Apr 17;10:23. doi: 10.1186/1471-2431-10-23. Review.

19.

In vitro selection of Plasmodium falciparum drug-resistant parasite lines.

Nzila A, Mwai L.

J Antimicrob Chemother. 2010 Mar;65(3):390-8. doi: 10.1093/jac/dkp449. Epub 2009 Dec 18. Review.

20.

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

Mwai L, Kiara SM, Abdirahman A, Pole L, Rippert A, Diriye A, Bull P, Marsh K, Borrmann S, Nzila A.

Antimicrob Agents Chemother. 2009 Dec;53(12):5069-73. doi: 10.1128/AAC.00638-09. Epub 2009 Sep 21.

21.

In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.

Kiara SM, Okombo J, Masseno V, Mwai L, Ochola I, Borrmann S, Nzila A.

Antimicrob Agents Chemother. 2009 Sep;53(9):3793-8. doi: 10.1128/AAC.00308-09. Epub 2009 Jun 15.

22.

Chloroquine resistance before and after its withdrawal in Kenya.

Mwai L, Ochong E, Abdirahman A, Kiara SM, Ward S, Kokwaro G, Sasi P, Marsh K, Borrmann S, Mackinnon M, Nzila A.

Malar J. 2009 May 18;8:106. doi: 10.1186/1475-2875-8-106.

23.

In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa.

Sasi P, Abdulrahaman A, Mwai L, Muriithi S, Straimer J, Schieck E, Rippert A, Bashraheil M, Salim A, Peshu J, Awuondo K, Lowe B, Pirmohamed M, Winstanley P, Ward S, Nzila A, Borrmann S.

J Infect Dis. 2009 Jun 1;199(11):1575-82. doi: 10.1086/598862.

PMID:
19405863
24.

The Role for Osmotic Agents in Children with Acute Encephalopathies: A Systematic Review.

Gwer S, Gatakaa H, Mwai L, Idro R, Newton CR.

JBI Libr Syst Rev. 2009;7(5):154-174.

PMID:
27820068
25.

Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer.

Nduati E, Diriye A, Ommeh S, Mwai L, Kiara S, Masseno V, Kokwaro G, Nzila A.

Parasitol Res. 2008 May;102(6):1227-34. doi: 10.1007/s00436-008-0897-4. Epub 2008 Feb 9.

26.

Neurotoxicity of antimalarial drugs: a systematic review.

Mwai L, Gwer S, Gatakaa H, Kokwaro G, Newton C.

JBI Libr Syst Rev. 2008;6(12 Suppl):1-14. No abstract available.

PMID:
27820468
27.

Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria.

Kokwaro G, Mwai L, Nzila A.

Expert Opin Pharmacother. 2007 Jan;8(1):75-94. Review.

PMID:
17163809

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