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Items: 1 to 50 of 58

1.

Mitochondrial and nuclear multilocus phylogeny of Rhipicephalus ticks from Kenya.

Kanduma EG, Bishop RP, Githaka NW, Skilton RA, Heyne H, Mwacharo JM.

Mol Phylogenet Evol. 2019 Aug 9:106579. doi: 10.1016/j.ympev.2019.106579. [Epub ahead of print]

PMID:
31404610
2.

Novel and known signals of selection for fat deposition in domestic sheep breeds from Africa and Eurasia.

Mastrangelo S, Bahbahani H, Moioli B, Ahbara A, Al Abri M, Almathen F, da Silva A, Belabdi I, Portolano B, Mwacharo JM, Hanotte O, Pilla F, Ciani E.

PLoS One. 2019 Jun 14;14(6):e0209632. doi: 10.1371/journal.pone.0209632. eCollection 2019.

3.

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 E on blood stage immunity in young Kenyan children.

Ndungu FM, Mwacharo J, Wambua J, Njuguna P, Marsh K, Drakeley C, Bejon P.

Wellcome Open Res. 2019 Mar 5;4:42. doi: 10.12688/wellcomeopenres.15002.1. eCollection 2019.

4.

Livestock Genomics for Developing Countries - African Examples in Practice.

Marshall K, Gibson JP, Mwai O, Mwacharo JM, Haile A, Getachew T, Mrode R, Kemp SJ.

Front Genet. 2019 Apr 24;10:297. doi: 10.3389/fgene.2019.00297. eCollection 2019. Review.

5.

Repeated clinical malaria episodes are associated with modification of the immune system in children.

Bediako Y, Adams R, Reid AJ, Valletta JJ, Ndungu FM, Sodenkamp J, Mwacharo J, Ngoi JM, Kimani D, Kai O, Wambua J, Nyangweso G, de Villiers EP, Sanders M, Lotkowska ME, Lin JW, Manni S, Addy JWG, Recker M, Newbold C, Berriman M, Bejon P, Marsh K, Langhorne J.

BMC Med. 2019 Mar 13;17(1):60. doi: 10.1186/s12916-019-1292-y.

6.

Genetic diversity and matrilineal genetic origin of fat-rumped sheep in Ethiopia.

Nigussie H, Mwacharo JM, Osama S, Agaba M, Mekasha Y, Kebede K, Abegaz S, Pal SK.

Trop Anim Health Prod. 2019 Jul;51(6):1393-1404. doi: 10.1007/s11250-019-01827-z. Epub 2019 Feb 24.

PMID:
30798433
7.

Genome-Wide Variation, Candidate Regions and Genes Associated With Fat Deposition and Tail Morphology in Ethiopian Indigenous Sheep.

Ahbara A, Bahbahani H, Almathen F, Al Abri M, Agoub MO, Abeba A, Kebede A, Musa HH, Mastrangelo S, Pilla F, Ciani E, Hanotte O, Mwacharo JM.

Front Genet. 2019 Jan 9;9:699. doi: 10.3389/fgene.2018.00699. eCollection 2018.

8.

Genomic Selection and Use of Molecular Tools in Breeding Programs for Indigenous and Crossbred Cattle in Developing Countries: Current Status and Future Prospects.

Mrode R, Ojango JMK, Okeyo AM, Mwacharo JM.

Front Genet. 2019 Jan 9;9:694. doi: 10.3389/fgene.2018.00694. eCollection 2018. Review.

9.

Population structure, genetic diversity and selection signatures within seven indigenous Pakistani goat populations.

Kumar C, Song S, Dewani P, Kumar M, Parkash O, Ma Y, Malhi KK, Yang N, Mwacharo JM, He X, Jiang L.

Anim Genet. 2018 Dec;49(6):592-604. doi: 10.1111/age.12722. Epub 2018 Sep 19.

PMID:
30229969
10.

Whole-Genome Resequencing of Red Junglefowl and Indigenous Village Chicken Reveal New Insights on the Genome Dynamics of the Species.

Lawal RA, Al-Atiyat RM, Aljumaah RS, Silva P, Mwacharo JM, Hanotte O.

Front Genet. 2018 Jul 20;9:264. doi: 10.3389/fgene.2018.00264. eCollection 2018.

11.

Genome-wide discovery of lincRNAs with spatiotemporal expression patterns in the skin of goat during the cashmere growth cycle.

Song S, Yang M, Li Y, Rouzi M, Zhao Q, Pu Y, He X, Mwacharo JM, Yang N, Ma Y, Jiang L.

BMC Genomics. 2018 Jun 26;19(1):495. doi: 10.1186/s12864-018-4864-x.

12.

Polymorphisms in MC1R and ASIP Genes are Associated with Coat Color Variation in the Arabian Camel.

Almathen F, Elbir H, Bahbahani H, Mwacharo J, Hanotte O.

J Hered. 2018 Aug 24;109(6):700-706. doi: 10.1093/jhered/esy024.

13.

Genetic diversity and population structure of Theileria parva in South Sudan.

Salih DA, Mwacharo JM, Pelle R, Njahira MN, Odongo DO, Mbole-Kariuki MN, Marcellino WL, Malak AK, Kiara H, El Hussein ARM, Bishop RP, Skilton RA.

Ticks Tick Borne Dis. 2018 May;9(4):806-813. doi: 10.1016/j.ttbdis.2018.03.002. Epub 2018 Mar 3.

PMID:
29534988
14.

Mitochondrial DNA variation reveals maternal origins and demographic dynamics of Ethiopian indigenous goats.

Tarekegn GM, Tesfaye K, Mwai OA, Djikeng A, Dessie T, Birungi J, Osama S, Zergaw N, Alemu A, Achieng G, Tutah J, Mutai C, Njuguna J, Mwacharo JM.

Ecol Evol. 2018 Jan 3;8(3):1543-1553. doi: 10.1002/ece3.3710. eCollection 2018 Feb.

15.

Invited review: Genomic selection for small ruminants in developed countries: how applicable for the rest of the world?

Mrode R, Tarekegn GM, Mwacharo JM, Djikeng A.

Animal. 2018 Jul;12(7):1333-1340. doi: 10.1017/S1751731117003688. Epub 2018 Jan 18. Review.

16.

Signatures of positive selection in African Butana and Kenana dairy zebu cattle.

Bahbahani H, Salim B, Almathen F, Al Enezi F, Mwacharo JM, Hanotte O.

PLoS One. 2018 Jan 4;13(1):e0190446. doi: 10.1371/journal.pone.0190446. eCollection 2018.

17.

Genomic footprints of dryland stress adaptation in Egyptian fat-tail sheep and their divergence from East African and western Asia cohorts.

Mwacharo JM, Kim ES, Elbeltagy AR, Aboul-Naga AM, Rischkowsky BA, Rothschild MF.

Sci Rep. 2017 Dec 15;7(1):17647. doi: 10.1038/s41598-017-17775-3.

18.

Detecting Malaria Hotspots: A Comparison of Rapid Diagnostic Test, Microscopy, and Polymerase Chain Reaction.

Mogeni P, Williams TN, Omedo I, Kimani D, Ngoi JM, Mwacharo J, Morter R, Nyundo C, Wambua J, Nyangweso G, Kapulu M, Fegan G, Bejon P.

J Infect Dis. 2017 Nov 27;216(9):1091-1098. doi: 10.1093/infdis/jix321.

19.

Genes encoding two Theileria parva antigens recognized by CD8+ T-cells exhibit sequence diversity in South Sudanese cattle populations but the majority of alleles are similar to the Muguga component of the live vaccine cocktail.

Salih DA, Pelle R, Mwacharo JM, Njahira MN, Marcellino WL, Kiara H, Malak AK, El Hussein AR, Bishop R, Skilton RA.

PLoS One. 2017 Feb 23;12(2):e0171426. doi: 10.1371/journal.pone.0171426. eCollection 2017.

20.

Mitochondrial DNA D-loop haplogroup contributions to the genetic diversity of East European domestic chickens from Russia.

Dyomin AG, Danilova MI, Mwacharo JM, Masharsky AE, Panteleev AV, Druzhkova AS, Trifonov VA, Galkina SA.

J Anim Breed Genet. 2017 Apr;134(2):98-108. doi: 10.1111/jbg.12248. Epub 2016 Dec 18.

PMID:
27988972
21.

Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya.

Kanduma EG, Mwacharo JM, Githaka NW, Kinyanjui PW, Njuguna JN, Kamau LM, Kariuki E, Mwaura S, Skilton RA, Bishop RP.

Parasit Vectors. 2016 Jun 22;9(1):353. doi: 10.1186/s13071-016-1631-1.

22.

Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary.

Almathen F, Charruau P, Mohandesan E, Mwacharo JM, Orozco-terWengel P, Pitt D, Abdussamad AM, Uerpmann M, Uerpmann HP, De Cupere B, Magee P, Alnaqeeb MA, Salim B, Raziq A, Dessie T, Abdelhadi OM, Banabazi MH, Al-Eknah M, Walzer C, Faye B, Hofreiter M, Peters J, Hanotte O, Burger PA.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6707-12. doi: 10.1073/pnas.1519508113. Epub 2016 May 9.

23.

Multiple genomic signatures of selection in goats and sheep indigenous to a hot arid environment.

Kim ES, Elbeltagy AR, Aboul-Naga AM, Rischkowsky B, Sayre B, Mwacharo JM, Rothschild MF.

Heredity (Edinb). 2016 Mar;116(3):255-64. doi: 10.1038/hdy.2015.94. Epub 2015 Nov 11.

24.

Genome-wide analysis reveals the extent of EAV-HP integration in domestic chicken.

Wragg D, Mason AS, Yu L, Kuo R, Lawal RA, Desta TT, Mwacharo JM, Cho CY, Kemp S, Burt DW, Hanotte O.

BMC Genomics. 2015 Oct 14;16:784. doi: 10.1186/s12864-015-1954-x.

25.

Multi-locus genotyping reveals absence of genetic structure in field populations of the brown ear tick (Rhipicephalus appendiculatus) in Kenya.

Kanduma EG, Mwacharo JM, Mwaura S, Njuguna JN, Nzuki I, Kinyanjui PW, Githaka N, Heyne H, Hanotte O, Skilton RA, Bishop RP.

Ticks Tick Borne Dis. 2016 Feb;7(1):26-35. doi: 10.1016/j.ttbdis.2015.08.001. Epub 2015 Aug 5.

PMID:
26278352
26.

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults.

Ogwang C, Kimani D, Edwards NJ, Roberts R, Mwacharo J, Bowyer G, Bliss C, Hodgson SH, Njuguna P, Viebig NK, Nicosia A, Gitau E, Douglas S, Illingworth J, Marsh K, Lawrie A, Imoukhuede EB, Ewer K, Urban BC, Hill AVS, Bejon P; MVVC group.

Sci Transl Med. 2015 May 6;7(286):286re5. doi: 10.1126/scitranslmed.aaa2373.

27.

Historical demographic profiles and genetic variation of the East African Butana and Kenana indigenous dairy zebu cattle.

Salim B, Taha KM, Hanotte O, Mwacharo JM.

Anim Genet. 2014 Dec;45(6):782-90. doi: 10.1111/age.12225. Epub 2014 Oct 13.

PMID:
25308478
28.

Endogenous retrovirus EAV-HP linked to blue egg phenotype in Mapuche fowl.

Wragg D, Mwacharo JM, Alcalde JA, Wang C, Han JL, Gongora J, Gourichon D, Tixier-Boichard M, Hanotte O.

PLoS One. 2013 Aug 19;8(8):e71393. doi: 10.1371/journal.pone.0071393. eCollection 2013. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/2727de85-899f-4104-955d-1c5f3c0d3319. PLoS One. 2014;9(12):e116015.

29.

Reconstructing the origin and dispersal patterns of village chickens across East Africa: insights from autosomal markers.

Mwacharo JM, Nomura K, Hanada H, Han JL, Amano T, Hanotte O.

Mol Ecol. 2013 May;22(10):2683-97. doi: 10.1111/mec.12294.

30.

Insights into the genetic history of Green-legged Partridgelike fowl: mtDNA and genome-wide SNP analysis.

Siwek M, Wragg D, Sławińska A, Malek M, Hanotte O, Mwacharo JM.

Anim Genet. 2013 Aug;44(5):522-32. doi: 10.1111/age.12046. Epub 2013 Apr 24.

31.

Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya.

Ibison F, Olotu A, Muema DM, Mwacharo J, Ohuma E, Kimani D, Marsh K, Bejon P, Ndungu FM.

PLoS One. 2012;7(12):e52939. doi: 10.1371/journal.pone.0052939. Epub 2012 Dec 26.

32.

A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E.

Ndungu FM, Mwacharo J, Kimani D, Kai O, Moris P, Jongert E, Vekemans J, Olotu A, Bejon P.

PLoS One. 2012;7(12):e52870. doi: 10.1371/journal.pone.0052870. Epub 2012 Dec 27.

33.

The History of African Village Chickens: an Archaeological and Molecular Perspective.

Mwacharo JM, Bjørnstad G, Han JL, Hanotte O.

Afr Archaeol Rev. 2013;30:97-114. Epub 2013 Mar 3. Review.

34.

Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion.

Illingworth J, Butler NS, Roetynck S, Mwacharo J, Pierce SK, Bejon P, Crompton PD, Marsh K, Ndungu FM.

J Immunol. 2013 Feb 1;190(3):1038-47. doi: 10.4049/jimmunol.1202438. Epub 2012 Dec 21.

35.

Micro- and minisatellite-expressed sequence tag (EST) markers discriminate between populations of Rhipicephalus appendiculatus.

Kanduma EG, Mwacharo JM, Sunter JD, Nzuki I, Mwaura S, Kinyanjui PW, Kibe M, Heyne H, Hanotte O, Skilton RA, Bishop RP.

Ticks Tick Borne Dis. 2012 Jun;3(3):128-36. doi: 10.1016/j.ttbdis.2012.05.001. Epub 2012 Jul 11.

PMID:
22789728
36.

Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children.

Ndungu FM, Olotu A, Mwacharo J, Nyonda M, Apfeld J, Mramba LK, Fegan GW, Bejon P, Marsh K.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8247-52. doi: 10.1073/pnas.1200472109. Epub 2012 May 7.

37.

Analysis of genome-wide structure, diversity and fine mapping of Mendelian traits in traditional and village chickens.

Wragg D, Mwacharo JM, Alcalde JA, Hocking PM, Hanotte O.

Heredity (Edinb). 2012 Jul;109(1):6-18. doi: 10.1038/hdy.2012.9. Epub 2012 Mar 7.

38.

Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria.

Olotu A, Moris P, Mwacharo J, Vekemans J, Kimani D, Janssens M, Kai O, Jongert E, Lievens M, Leach A, Villafana T, Savarese B, Marsh K, Cohen J, Bejon P.

PLoS One. 2011;6(10):e25786. doi: 10.1371/journal.pone.0025786. Epub 2011 Oct 6.

39.

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children.

Bejon P, Cook J, Bergmann-Leitner E, Olotu A, Lusingu J, Mwacharo J, Vekemans J, Njuguna P, Leach A, Lievens M, Dutta S, von Seidlein L, Savarese B, Villafana T, Lemnge MM, Cohen J, Marsh K, Corran PH, Angov E, Riley EM, Drakeley CJ.

J Infect Dis. 2011 Jul 1;204(1):9-18. doi: 10.1093/infdis/jir222.

40.

Clearance of asymptomatic P. falciparum Infections Interacts with the number of clones to predict the risk of subsequent malaria in Kenyan children.

Liljander A, Bejon P, Mwacharo J, Kai O, Ogada E, Peshu N, Marsh K, Färnert A.

PLoS One. 2011 Feb 24;6(2):e16940. doi: 10.1371/journal.pone.0016940.

41.

East Asian contributions to Dutch traditional and western commercial chickens inferred from mtDNA analysis.

Dana N, Megens HJ, Crooijmans RP, Hanotte O, Mwacharo J, Groenen MA, van Arendonk JA.

Anim Genet. 2011 Apr;42(2):125-33. doi: 10.1111/j.1365-2052.2010.02134.x. Epub 2010 Dec 10.

PMID:
21143489
42.

Mitochondrial DNA reveals multiple introductions of domestic chicken in East Africa.

Mwacharo JM, Bjørnstad G, Mobegi V, Nomura K, Hanada H, Amano T, Jianlin H, Hanotte O.

Mol Phylogenet Evol. 2011 Feb;58(2):374-82. doi: 10.1016/j.ympev.2010.11.027. Epub 2010 Dec 5.

PMID:
21138772
43.

Quantitative PCR evaluation of cellular immune responses in Kenyan children vaccinated with a candidate malaria vaccine.

Mwacharo J, Dunachie SJ, Kai O, Hill AV, Bejon P, Fletcher HA.

PLoS One. 2009 Dec 23;4(12):e8434. doi: 10.1371/journal.pone.0008434. Erratum in: PLoS One. 2011;6(2). doi: 10.1371/annotation/9a1d1873-2f7e-4d69-a1b0-8e3797e8093a.

44.

Prevalence of serum neutralizing antibodies against chimpanzee adenovirus 63 and human adenovirus 5 in Kenyan children, in the context of vaccine vector efficacy.

Dudareva M, Andrews L, Gilbert SC, Bejon P, Marsh K, Mwacharo J, Kai O, Nicosia A, Hill AV.

Vaccine. 2009 Jun 2;27(27):3501-4. doi: 10.1016/j.vaccine.2009.03.080. Epub 2009 Apr 16.

PMID:
19464527
45.

Genetic relationships among Kenyan and other East African indigenous chickens.

Mwacharo JM, Nomura K, Hanada H, Jianlin H, Hanotte O, Amano T.

Anim Genet. 2007 Oct;38(5):485-90.

PMID:
17894562
46.

The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum.

Bejon P, Mwacharo J, Kai O, Todryk S, Keating S, Lowe B, Lang T, Mwangi TW, Gilbert SC, Peshu N, Marsh K, Hill AV.

J Immunol. 2007 Sep 15;179(6):4193-201.

47.

The small east african shorthorn zebu cows in Kenya. I: linear body measurements.

Mwacharo JM, Okeyo AM, Kamande GK, Rege JE.

Trop Anim Health Prod. 2006 Jan;38(1):65-74.

PMID:
17405630
48.

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya.

Bejon P, Mwacharo J, Kai O, Mwangi T, Milligan P, Todryk S, Keating S, Lang T, Lowe B, Gikonyo C, Molyneux C, Fegan G, Gilbert SC, Peshu N, Marsh K, Hill AV.

PLoS Clin Trials. 2006 Oct 20;1(6):e29.

49.

Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals.

Bejon P, Keating S, Mwacharo J, Kai OK, Dunachie S, Walther M, Berthoud T, Lang T, Epstein J, Carucci D, Moris P, Cohen J, Gilbert SC, Peshu N, Marsh K, Hill AV.

Infect Immun. 2006 Nov;74(11):6331-8. Epub 2006 Sep 11.

50.

Alternating vector immunizations encoding pre-erythrocytic malaria antigens enhance memory responses in a malaria endemic area.

Bejon P, Kai OK, Mwacharo J, Keating S, Lang T, Gilbert SC, Peshu N, Marsh K, Hill AV.

Eur J Immunol. 2006 Aug;36(8):2264-72.

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