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Items: 12


Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for Cancer.

Muvarak NE, Chowdhury K, Xia L, Robert C, Choi EY, Cai Y, Bellani M, Zou Y, Singh ZN, Duong VH, Rutherford T, Nagaria P, Bentzen SM, Seidman MM, Baer MR, Lapidus RG, Baylin SB, Rassool FV.

Cancer Cell. 2016 Oct 10;30(4):637-650. doi: 10.1016/j.ccell.2016.09.002.


Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2.

Lapidus RG, Carter-Cooper BA, Sadowska M, Choi EY, Wonodi O, Muvarak N, Natarajan K, Pidugu LS, Jaiswal A, Toth EA, Rassool FV, Etemadi A, Sausville EA, Baer MR, Emadi A.

Pharmaceuticals (Basel). 2016 Jan 19;9(1). pii: E4. doi: 10.3390/ph9010004.


c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias.

Muvarak N, Kelley S, Robert C, Baer MR, Perrotti D, Gambacorti-Passerini C, Civin C, Scheibner K, Rassool FV.

Mol Cancer Res. 2015 Apr;13(4):699-712. doi: 10.1158/1541-7786.MCR-14-0422. Epub 2015 Mar 31.


Genomic instability in chronic myeloid leukemia: targets for therapy?

Muvarak N, Nagaria P, Rassool FV.

Curr Hematol Malig Rep. 2012 Jun;7(2):94-102. doi: 10.1007/s11899-012-0119-0.


Novel, Broad Spectrum Anti-Cancer Agents Containing the Tricyclic 5:7:5-Fused Diimidazodiazepine Ring System.

Kondaskar A, Kondaskar S, Kumar R, Fishbein JC, Muvarak N, Lapidus RG, Sadowska M, Edelman MJ, Bol GM, Vesuna F, Raman V, Hosmane RS.

ACS Med Chem Lett. 2010 Dec 31;2(3):252-256.


Robust in vivo transduction of nervous system and neural stem cells by early gestational intra amniotic gene transfer using lentiviral vector.

Stitelman DH, Endo M, Bora A, Muvarak N, Zoltick PW, Flake AW, Brazelton TR.

Mol Ther. 2010 Sep;18(9):1615-23. doi: 10.1038/mt.2010.125. Epub 2010 Jun 22.


Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes.

Niiya M, Endo M, Shang D, Zoltick PW, Muvarak NE, Cao W, Jin SY, Skipwith CG, Motto DG, Flake AW, Zheng XL.

Mol Ther. 2009 Jan;17(1):34-41. doi: 10.1038/mt.2008.223. Epub 2008 Oct 28.


Apoptotic cell-mediated immunoregulation of dendritic cells does not require iC3b opsonization.

Behrens EM, Ning Y, Muvarak N, Zoltick PW, Flake AW, Gallucci S.

J Immunol. 2008 Sep 1;181(5):3018-26.


IL-10 overexpression decreases inflammatory mediators and promotes regenerative healing in an adult model of scar formation.

Peranteau WH, Zhang L, Muvarak N, Badillo AT, Radu A, Zoltick PW, Liechty KW.

J Invest Dermatol. 2008 Jul;128(7):1852-60. doi: 10.1038/sj.jid.5701232. Epub 2008 Jan 17.


Efficient in vivo targeting of epidermal stem cells by early gestational intraamniotic injection of lentiviral vector driven by the keratin 5 promoter.

Endo M, Zoltick PW, Peranteau WH, Radu A, Muvarak N, Ito M, Yang Z, Cotsarelis G, Flake AW.

Mol Ther. 2008 Jan;16(1):131-7. Epub 2007 Oct 9.


Gene transfer to ocular stem cells by early gestational intraamniotic injection of lentiviral vector.

Endo M, Zoltick PW, Chung DC, Bennett J, Radu A, Muvarak N, Flake AW.

Mol Ther. 2007 Mar;15(3):579-87. Epub 2007 Jan 23.


Linked mechanical and biological aspects of remodeling in mouse pulmonary arteries with hypoxia-induced hypertension.

Kobs RW, Muvarak NE, Eickhoff JC, Chesler NC.

Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1209-17. Epub 2004 Nov 4.

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