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Items: 1 to 50 of 60

1.

Inhibition of collagen production delays malignant mesothelioma tumor growth in a murine model.

Abayasiriwardana KS, Wood MK, Prêle CM, Birnie KA, Robinson BW, Laurent GJ, McAnulty RJ, Mutsaers SE.

Biochem Biophys Res Commun. 2019 Mar 5;510(2):198-204. doi: 10.1016/j.bbrc.2019.01.057. Epub 2019 Jan 23.

PMID:
30685089
2.

STAT3 Regulates the Onset of Oxidant-Induced Senescence in Lung Fibroblasts.

Waters DW, Blokland KEC, Pathinayake PS, Wei L, Schuliga M, Jaffar J, Westall GP, Hansbro PM, Prele CM, Mutsaers SE, Bartlett NW, Burgess JK, Grainge CL, Knight DA.

Am J Respir Cell Mol Biol. 2019 Jan 4. doi: 10.1165/rcmb.2018-0328OC. [Epub ahead of print]

PMID:
30608861
3.

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.

Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaar8356. doi: 10.1126/scitranslmed.aar8356.

4.

Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.

Schuliga M, Pechkovsky DV, Read J, Waters DW, Blokland KEC, Reid AT, Hogaboam CM, Khalil N, Burgess JK, Prêle CM, Mutsaers SE, Jaffar J, Westall G, Grainge C, Knight DA.

J Cell Mol Med. 2018 Dec;22(12):5847-5861. doi: 10.1111/jcmm.13855. Epub 2018 Sep 26.

5.

Epigenetic Control of CXCL10: Regulating the Counterregulator in Idiopathic Pulmonary Fibrosis.

Roman J, Mutsaers SE.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):419-420. doi: 10.1165/rcmb.2017-0389ED. No abstract available.

PMID:
29717923
6.

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis.

Waters DW, Blokland KEC, Pathinayake PS, Burgess JK, Mutsaers SE, Prele CM, Schuliga M, Grainge CL, Knight DA.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L162-L172. doi: 10.1152/ajplung.00037.2018. Epub 2018 Apr 26.

PMID:
29696986
7.

Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma.

Birnie KA, Prêle CM, Thompson PJ, Badrian B, Mutsaers SE.

Oncotarget. 2017 Aug 24;8(44):78193-78207. doi: 10.18632/oncotarget.20409. eCollection 2017 Sep 29. Review.

8.

Idiopathic pulmonary fibrosis and a role for autoimmunity.

Hoyne GF, Elliott H, Mutsaers SE, Prêle CM.

Immunol Cell Biol. 2017 Aug;95(7):577-583. doi: 10.1038/icb.2017.22. Epub 2017 Mar 30. Review.

PMID:
28356570
9.

A Subset of Malignant Mesothelioma Tumors Retain Osteogenic Potential.

Lansley SM, Pedersen B, Robinson C, Searles RG, Sterrett G, van Bruggen I, Lake RA, Mutsaers SE, Prêle CM.

Sci Rep. 2016 Nov 25;6:36349. doi: 10.1038/srep36349.

10.

Mesothelial cells and peritoneal homeostasis.

Mutsaers SE, Prêle CM, Pengelly S, Herrick SE.

Fertil Steril. 2016 Oct;106(5):1018-1024. doi: 10.1016/j.fertnstert.2016.09.005. Review.

PMID:
27692285
11.

Mesothelial cells in tissue repair and fibrosis.

Mutsaers SE, Birnie K, Lansley S, Herrick SE, Lim CB, Prêle CM.

Front Pharmacol. 2015 Jun 9;6:113. doi: 10.3389/fphar.2015.00113. eCollection 2015. Review.

12.

Loss of miR-223 and JNK Signaling Contribute to Elevated Stathmin in Malignant Pleural Mesothelioma.

Birnie KA, Yip YY, Ng DC, Kirschner MB, Reid G, Prêle CM, Musk AW, Lee YC, Thompson PJ, Mutsaers SE, Badrian B.

Mol Cancer Res. 2015 Jul;13(7):1106-18. doi: 10.1158/1541-7786.MCR-14-0442. Epub 2015 Mar 30.

13.

Peritoneal Tumorigenesis and Inflammation are Ameliorated by Humidified-Warm Carbon Dioxide Insufflation in the Mouse.

Carpinteri S, Sampurno S, Bernardi MP, Germann M, Malaterre J, Heriot A, Chambers BA, Mutsaers SE, Lynch AC, Ramsay RG.

Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1540-7. doi: 10.1245/s10434-015-4508-1. Epub 2015 Mar 21.

14.

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis.

Lim CB, Prêle CM, Baltic S, Arthur PG, Creaney J, Watkins DN, Thompson PJ, Mutsaers SE.

Oncotarget. 2015 Jan 30;6(3):1519-30.

15.

Long-term exposure of mesothelial cells to SV40 and asbestos leads to malignant transformation and chemotherapy resistance.

Cleaver AL, Bhamidipaty K, Wylie B, Connor T, Robinson C, Robinson BW, Mutsaers SE, Lake RA.

Carcinogenesis. 2014 Feb;35(2):407-14. doi: 10.1093/carcin/bgt322. Epub 2013 Oct 15.

PMID:
24130165
16.

Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells.

Fox SA, Richards AK, Kusumah I, Perumal V, Bolitho EM, Mutsaers SE, Dharmarajan AM.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):82-7. doi: 10.1016/j.bbrc.2013.09.025. Epub 2013 Sep 13.

PMID:
24041698
17.

Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.

Lim CB, Prêle CM, Cheah HM, Cheng YY, Klebe S, Reid G, Watkins DN, Baltic S, Thompson PJ, Mutsaers SE.

PLoS One. 2013 Jun 24;8(6):e66685. doi: 10.1371/journal.pone.0066685. Print 2013.

18.

STAT3: a central mediator of pulmonary fibrosis?

Prêle CM, Yao E, O'Donoghue RJ, Mutsaers SE, Knight DA.

Proc Am Thorac Soc. 2012 Jul;9(3):177-82. doi: 10.1513/pats.201201-007AW. Review. Erratum in: Proc Am Thorac Soc. 2012 Oct;9(4):210.

PMID:
22802294
19.

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.

O'Donoghue RJ, Knight DA, Richards CD, Prêle CM, Lau HL, Jarnicki AG, Jones J, Bozinovski S, Vlahos R, Thiem S, McKenzie BS, Wang B, Stumbles P, Laurent GJ, McAnulty RJ, Rose-John S, Zhu HJ, Anderson GP, Ernst MR, Mutsaers SE.

EMBO Mol Med. 2012 Sep;4(9):939-51. doi: 10.1002/emmm.201100604. Epub 2012 Jun 8.

20.

Increased circulating miR-625-3p: a potential biomarker for patients with malignant pleural mesothelioma.

Kirschner MB, Cheng YY, Badrian B, Kao SC, Creaney J, Edelman JJ, Armstrong NJ, Vallely MP, Musk AW, Robinson BW, McCaughan BC, Klebe S, Mutsaers SE, van Zandwijk N, Reid G.

J Thorac Oncol. 2012 Jul;7(7):1184-91. doi: 10.1097/JTO.0b013e3182572e83.

21.

STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF.

Pechkovsky DV, Prêle CM, Wong J, Hogaboam CM, McAnulty RJ, Laurent GJ, Zhang SS, Selman M, Mutsaers SE, Knight DA.

Am J Pathol. 2012 Apr;180(4):1398-412. doi: 10.1016/j.ajpath.2011.12.022. Epub 2012 Feb 7.

PMID:
22322297
22.

Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia.

Prêle CM, Reichelt ME, Mutsaers SE, Davies M, Delbridge LM, Headrick JP, Rosenthal N, Bogoyevitch MA, Grounds MD.

Cardiovasc Pathol. 2012 Jan-Feb;21(1):17-27. doi: 10.1016/j.carpath.2010.11.008. Epub 2011 Jan 26.

PMID:
21266309
23.

Mesothelial cell differentiation into osteoblast- and adipocyte-like cells.

Lansley SM, Searles RG, Hoi A, Thomas C, Moneta H, Herrick SE, Thompson PJ, Newman M, Sterrett GF, Prêle CM, Mutsaers SE.

J Cell Mol Med. 2011 Oct;15(10):2095-105. doi: 10.1111/j.1582-4934.2010.01212.x.

24.

STAT3 in tissue fibrosis: is there a role in the lung?

Knight D, Mutsaers SE, Prêle CM.

Pulm Pharmacol Ther. 2011 Apr;24(2):193-8. doi: 10.1016/j.pupt.2010.10.005. Epub 2010 Oct 15. Review.

PMID:
20951825
25.

c-Jun N-terminal kinase/c-Jun inhibits fibroblast proliferation by negatively regulating the levels of stathmin/oncoprotein 18.

Yeap YY, Ng IH, Badrian B, Nguyen TV, Yip YY, Dhillon AS, Mutsaers SE, Silke J, Bogoyevitch MA, Ng DC.

Biochem J. 2010 Sep 1;430(2):345-54. doi: 10.1042/BJ20100425.

PMID:
20594188
26.

Current clinical trials for the treatment of idiopathic pulmonary fibrosis.

Klingsberg RC, Mutsaers SE, Lasky JA.

Respirology. 2010 Jan;15(1):19-31. doi: 10.1111/j.1440-1843.2009.01672.x. Review.

PMID:
20199632
27.

Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production.

Haegens A, Heeringa P, van Suylen RJ, Steele C, Aratani Y, O'Donoghue RJ, Mutsaers SE, Mossman BT, Wouters EF, Vernooy JH.

J Immunol. 2009 Jun 15;182(12):7990-6. doi: 10.4049/jimmunol.0800377.

28.

Spontaneously immortalized mouse mesothelial cells display characteristics of malignant transformation.

Sherwood AL, Mutsaers SE, Peeva VK, Robinson C, DeSilva CJ, Swanson NR, Lake RA.

Cell Prolif. 2008 Dec;41(6):894-908. doi: 10.1111/j.1365-2184.2008.00560.x.

PMID:
19040568
29.

Structure and function of mesothelial cells.

Mutsaers SE, Wilkosz S.

Cancer Treat Res. 2007;134:1-19. Review.

PMID:
17633044
30.

Future directions in mesothelial transplantation research.

Mutsaers SE, Di Paolo N.

Int J Artif Organs. 2007 Jun;30(6):557-61. Review. No abstract available.

PMID:
17628857
31.

The potential of mesothelial cells in tissue engineering and regenerative medicine applications.

Herrick SE, Mutsaers SE.

Int J Artif Organs. 2007 Jun;30(6):527-40. Review.

PMID:
17628854
32.

The origin of regenerating mesothelium: a historical perspective.

Mutsaers SE, Prêle CM, Lansley SM, Herrick SE.

Int J Artif Organs. 2007 Jun;30(6):484-94. Review.

PMID:
17628849
33.

Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis.

Chua F, Dunsmore SE, Clingen PH, Mutsaers SE, Shapiro SD, Segal AW, Roes J, Laurent GJ.

Am J Pathol. 2007 Jan;170(1):65-74.

34.

Growth factors in pleural fibrosis.

Mutsaers SE, Kalomenidis I, Wilson NA, Lee YC.

Curr Opin Pulm Med. 2006 Jul;12(4):251-8. Review.

PMID:
16825876
35.

Pathogenesis of pleural fibrosis.

Mutsaers SE, Prele CM, Brody AR, Idell S.

Respirology. 2004 Nov;9(4):428-40. Review.

PMID:
15612953
36.

Mesothelial progenitor cells and their potential in tissue engineering.

Herrick SE, Mutsaers SE.

Int J Biochem Cell Biol. 2004 Apr;36(4):621-42. Review.

PMID:
15010328
37.

The mesothelial cell.

Mutsaers SE.

Int J Biochem Cell Biol. 2004 Jan;36(1):9-16. Review.

PMID:
14592528
38.

The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?

Knight DA, Ernst M, Anderson GP, Moodley YP, Mutsaers SE.

Pharmacol Ther. 2003 Sep;99(3):327-38.

PMID:
12951164
39.

Short course dexamethasone treatment following injury inhibits bleomycin induced fibrosis in rats.

Dik WA, McAnulty RJ, Versnel MA, Naber BA, Zimmermann LJ, Laurent GJ, Mutsaers SE.

Thorax. 2003 Sep;58(9):765-71.

40.

Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation.

Moodley YP, Scaffidi AK, Misso NL, Keerthisingam C, McAnulty RJ, Laurent GJ, Mutsaers SE, Thompson PJ, Knight DA.

Am J Pathol. 2003 Jul;163(1):345-54.

41.

Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation.

Bellingan GJ, Xu P, Cooksley H, Cauldwell H, Shock A, Bottoms S, Haslett C, Mutsaers SE, Laurent GJ.

J Exp Med. 2002 Dec 2;196(11):1515-21.

42.

Mesothelial cells: their structure, function and role in serosal repair.

Mutsaers SE.

Respirology. 2002 Sep;7(3):171-91. Review.

PMID:
12153683
43.

Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts.

Scaffidi AK, Mutsaers SE, Moodley YP, McAnulty RJ, Laurent GJ, Thompson PJ, Knight DA.

Br J Pharmacol. 2002 Jul;136(5):793-801.

44.

Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing.

Foley-Comer AJ, Herrick SE, Al-Mishlab T, Prêle CM, Laurent GJ, Mutsaers SE.

J Cell Sci. 2002 Apr 1;115(Pt 7):1383-9.

45.
46.

Presence and distribution of sensory nerve fibers in human peritoneal adhesions.

Sulaiman H, Gabella G, Davis MSc C, Mutsaers SE, Boulos P, Laurent GJ, Herrick SE.

Ann Surg. 2001 Aug;234(2):256-61.

47.

Evidence that neutrophil elastase-deficient mice are resistant to bleomycin-induced fibrosis.

Dunsmore SE, Roes J, Chua FJ, Segal AW, Mutsaers SE, Laurent GJ.

Chest. 2001 Jul;120(1 Suppl):35S-36S. No abstract available.

PMID:
11451907
48.

HGF/SF induces mesothelial cell migration and proliferation by autocrine and paracrine pathways.

Warn R, Harvey P, Warn A, Foley-Comer A, Heldin P, Versnel M, Arakaki N, Daikuhara Y, Laurent GJ, Herrick SE, Mutsaers SE.

Exp Cell Res. 2001 Jul 15;267(2):258-66.

PMID:
11426944
49.

Growth of nerve fibres into murine peritoneal adhesions.

Sulaiman H, Gabella G, Davis C, Mutsaers SE, Boulos P, Laurent GJ, Herrick SE.

J Pathol. 2000 Nov;192(3):396-403.

PMID:
11054724
50.

Human peritoneal adhesions are highly cellular, innervated, and vascularized.

Herrick SE, Mutsaers SE, Ozua P, Sulaiman H, Omer A, Boulos P, Foster ML, Laurent GJ.

J Pathol. 2000 Sep;192(1):67-72.

PMID:
10951402

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