Sort by
Items per page

Send to

Choose Destination

Search results

Items: 30


Regional Differences in Human Intestinal Drug Metabolism.

Iswandana R, Irianti MI, Oosterhuis D, Hofker HS, Merema MT, de Jager MH, Mutsaers HAM, Olinga P.

Drug Metab Dispos. 2018 Dec;46(12):1879-1885. doi: 10.1124/dmd.118.083428. Epub 2018 Oct 1.


In vitro and ex vivo anti-fibrotic effects of LY2109761, a small molecule inhibitor against TGF-β.

Luangmonkong T, Suriguga S, Adhyatmika A, Adlia A, Oosterhuis D, Suthisisang C, de Jong KP, Mutsaers HAM, Olinga P.

Toxicol Appl Pharmacol. 2018 Sep 15;355:127-137. doi: 10.1016/j.taap.2018.07.001. Epub 2018 Jul 3.


Targeting Oxidative Stress for the Treatment of Liver Fibrosis.

Luangmonkong T, Suriguga S, Mutsaers HAM, Groothuis GMM, Olinga P, Boersema M.

Rev Physiol Biochem Pharmacol. 2018;175:71-102. doi: 10.1007/112_2018_10.


Murine Precision-Cut Kidney Slices as an ex vivo Model to Evaluate the Role of Transforming Growth Factor-β1 Signaling in the Onset of Renal Fibrosis.

Stribos EGD, Seelen MA, van Goor H, Olinga P, Mutsaers HAM.

Front Physiol. 2017 Dec 12;8:1026. doi: 10.3389/fphys.2017.01026. eCollection 2017.


Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis.

Luangmonkong T, Suriguga S, Bigaeva E, Boersema M, Oosterhuis D, de Jong KP, Schuppan D, Mutsaers HAM, Olinga P.

Br J Pharmacol. 2017 Sep;174(18):3107-3117. doi: 10.1111/bph.13945. Epub 2017 Aug 11.


Non-invasive quantification of collagen turnover in renal transplant recipients.

Stribos EGD, Nielsen SH, Brix S, Karsdal MA, Seelen MA, van Goor H, Bakker SJL, Olinga P, Mutsaers HAM, Genovese F.

PLoS One. 2017 Apr 21;12(4):e0175898. doi: 10.1371/journal.pone.0175898. eCollection 2017.


Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

van den Brand JA, Mutsaers HA, van Zuilen AD, Blankestijn PJ, van den Broek PH, Russel FG, Masereeuw R, Wetzels JF.

PLoS One. 2016 Dec 29;11(12):e0168117. doi: 10.1371/journal.pone.0168117. eCollection 2016.


Editorial: Organ Fibrosis: Triggers, Pathways, and Cellular Plasticity.

Mutsaers HA, Olinga P.

Front Med (Lausanne). 2016 Nov 15;3:55. eCollection 2016. No abstract available.


Renal fibrosis in precision-cut kidney slices.

Stribos EG, Hillebrands JL, Olinga P, Mutsaers HA.

Eur J Pharmacol. 2016 Nov 5;790:57-61. doi: 10.1016/j.ejphar.2016.06.057. Epub 2016 Jun 30. Review.


Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis.

Westra IM, Mutsaers HA, Luangmonkong T, Hadi M, Oosterhuis D, de Jong KP, Groothuis GM, Olinga P.

Toxicol In Vitro. 2016 Sep;35:77-85. doi: 10.1016/j.tiv.2016.05.012. Epub 2016 May 26.


Organ- and species-specific biological activity of rosmarinic acid.

Iswandana R, Pham BT, van Haaften WT, Luangmonkong T, Oosterhuis D, Mutsaers HA, Olinga P.

Toxicol In Vitro. 2016 Apr;32:261-8. doi: 10.1016/j.tiv.2016.01.009. Epub 2016 Jan 19.


Precision-cut human kidney slices as a model to elucidate the process of renal fibrosis.

Stribos EGD, Luangmonkong T, Leliveld AM, de Jong IJ, van Son WJ, Hillebrands JL, Seelen MA, van Goor H, Olinga P, Mutsaers HAM.

Transl Res. 2016 Apr;170:8-16.e1. doi: 10.1016/j.trsl.2015.11.007. Epub 2015 Nov 25.


The Influence of Dietary Protein Intake on Mammalian Tryptophan and Phenolic Metabolites.

Poesen R, Mutsaers HA, Windey K, van den Broek PH, Verweij V, Augustijns P, Kuypers D, Jansen J, Evenepoel P, Verbeke K, Meijers B, Masereeuw R.

PLoS One. 2015 Oct 15;10(10):e0140820. doi: 10.1371/journal.pone.0140820. eCollection 2015.


Chronic Kidney Disease and Fibrosis: The Role of Uremic Retention Solutes.

Mutsaers HA, Stribos EG, Glorieux G, Vanholder R, Olinga P.

Front Med (Lausanne). 2015 Aug 31;2:60. doi: 10.3389/fmed.2015.00060. eCollection 2015. Review.


The Authors Reply.

Mutsaers HA, Masereeuw R, Olinga P.

Kidney Int. 2015 Sep;88(3):637. doi: 10.1038/ki.2015.188. No abstract available.


Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology.

Mutsaers HA, Caetano-Pinto P, Seegers AE, Dankers AC, van den Broek PH, Wetzels JF, van den Brand JA, van den Heuvel LP, Hoenderop JG, Wilmer MJ, Masereeuw R.

Toxicol In Vitro. 2015 Oct;29(7):1868-77. doi: 10.1016/j.tiv.2015.07.020. Epub 2015 Jul 26.


Altered tryptophan metabolism and CKD-associated fatigue.

Mutsaers HA, Masereeuw R, Olinga P.

Kidney Int. 2014 Nov;86(5):1061-2. doi: 10.1038/ki.2014.237. No abstract available.


The kidney and uremic toxin removal: glomerulus or tubule?

Masereeuw R, Mutsaers HA, Toyohara T, Abe T, Jhawar S, Sweet DH, Lowenstein J.

Semin Nephrol. 2014 Mar;34(2):191-208. doi: 10.1016/j.semnephrol.2014.02.010. Epub 2014 Feb 18.


Switch in FGFR3 and -4 expression profile during human renal development may account for transient hypercalcemia in patients with Sotos syndrome due to 5q35 microdeletions.

Mutsaers HA, Levtchenko EN, Martinerie L, Pertijs JC, Allegaert K, Devriendt K, Masereeuw R, Monnens LA, Lombès M.

J Clin Endocrinol Metab. 2014 Jul;99(7):E1361-7. doi: 10.1210/jc.2014-1123. Epub 2014 Mar 26.


A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue.

Jansen J, Schophuizen CM, Wilmer MJ, Lahham SH, Mutsaers HA, Wetzels JF, Bank RA, van den Heuvel LP, Hoenderop JG, Masereeuw R.

Exp Cell Res. 2014 Apr 15;323(1):87-99. doi: 10.1016/j.yexcr.2014.02.011. Epub 2014 Feb 18.


Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients.

Mutsaers HA, Engelke UF, Wilmer MJ, Wetzels JF, Wevers RA, van den Heuvel LP, Hoenderop JG, Masereeuw R.

PLoS One. 2013 Aug 2;8(8):e71199. doi: 10.1371/journal.pone.0071199. Print 2013.


Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP).

Dankers AC, Mutsaers HA, Dijkman HB, van den Heuvel LP, Hoenderop JG, Sweep FC, Russel FG, Masereeuw R.

Biochim Biophys Acta. 2013 Oct;1832(10):1715-22. doi: 10.1016/j.bbadis.2013.05.002. Epub 2013 May 9.


Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration.

Mutsaers HA, Wilmer MJ, Reijnders D, Jansen J, van den Broek PH, Forkink M, Schepers E, Glorieux G, Vanholder R, van den Heuvel LP, Hoenderop JG, Masereeuw R.

Biochim Biophys Acta. 2013 Jan;1832(1):142-50. doi: 10.1016/j.bbadis.2012.09.006. Epub 2012 Sep 24.


Cryptography in modern-day medical science.

Mutsaers HA.

Med J Aust. 2012 Sep 17;197(6):353. No abstract available.


Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity.

Moghadasali R, Mutsaers HA, Azarnia M, Aghdami N, Baharvand H, Torensma R, Wilmer MJ, Masereeuw R.

Exp Toxicol Pathol. 2013 Jul;65(5):595-600. doi: 10.1016/j.etp.2012.06.002. Epub 2012 Jun 21.


Dexamethasone enhances oxidative stress-induced cell death in murine neural stem cells.

Mutsaers HA, Tofighi R.

Neurotox Res. 2012 Aug;22(2):127-37. doi: 10.1007/s12640-012-9308-9. Epub 2012 Jan 12.


Basolateral transport of the uraemic toxin p-cresyl sulfate: role for organic anion transporters?

Mutsaers HA, Wilmer MJ, van den Heuvel LP, Hoenderop JG, Masereeuw R.

Nephrol Dial Transplant. 2011 Dec;26(12):4149. doi: 10.1093/ndt/gfr562. Epub 2011 Oct 24. No abstract available.


Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

Mutsaers HA, van den Heuvel LP, Ringens LH, Dankers AC, Russel FG, Wetzels JF, Hoenderop JG, Masereeuw R.

PLoS One. 2011 Apr 4;6(4):e18438. doi: 10.1371/journal.pone.0018438.


Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis.

Scharstuhl A, Mutsaers HA, Pennings SW, Russel FG, Wagener FA.

PLoS One. 2009 Aug 20;4(8):e6688. doi: 10.1371/journal.pone.0006688.


Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation.

Scharstuhl A, Mutsaers HA, Pennings SW, Szarek WA, Russel FG, Wagener FA.

J Cell Mol Med. 2009 Apr;13(4):712-25. doi: 10.1111/j.1582-4934.2008.00339.x. Epub 2008 Apr 10.

Supplemental Content

Loading ...
Support Center