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Items: 31

1.

Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment.

Theodoraki MN, Yerneni S, Sarkar SN, Orr B, Muthuswamy R, Voyten J, Modugno F, Jiang W, Grimm M, Basse PH, Bartlett DL, Edwards RP, Kalinski P.

Cancer Res. 2018 Aug 1;78(15):4292-4302. doi: 10.1158/0008-5472.CAN-17-3985. Epub 2018 May 31.

PMID:
29853604
2.

Promoting the accumulation of tumor-specific T cells in tumor tissues by dendritic cell vaccines and chemokine-modulating agents.

Obermajer N, Urban J, Wieckowski E, Muthuswamy R, Ravindranathan R, Bartlett DL, Kalinski P.

Nat Protoc. 2018 Feb;13(2):335-357. doi: 10.1038/nprot.2017.130. Epub 2018 Jan 18.

PMID:
29345636
3.

Epinephrine promotes COX-2-dependent immune suppression in myeloid cells and cancer tissues.

Muthuswamy R, Okada NJ, Jenkins FJ, McGuire K, McAuliffe PF, Zeh HJ, Bartlett DL, Wallace C, Watkins S, Henning JD, Bovbjerg DH, Kalinski P.

Brain Behav Immun. 2017 May;62:78-86. doi: 10.1016/j.bbi.2017.02.008. Epub 2017 Feb 16.

PMID:
28212885
4.

Migration of dendritic cells to the lymph nodes and its enhancement to drive anti-tumor responses.

Seyfizadeh N, Muthuswamy R, Mitchell DA, Nierkens S, Seyfizadeh N.

Crit Rev Oncol Hematol. 2016 Nov;107:100-110. doi: 10.1016/j.critrevonc.2016.09.002. Epub 2016 Sep 9. Review.

PMID:
27823637
5.

Functional reprogramming of human prostate cancer to promote local attraction of effector CD8(+) T cells.

Muthuswamy R, Corman JM, Dahl K, Chatta GS, Kalinski P.

Prostate. 2016 Sep;76(12):1095-105. doi: 10.1002/pros.23194. Epub 2016 May 16.

PMID:
27199259
6.

Anatomical investigation of flower of Butea monosperma Lam.

Muthuswamy R, Senthamarai R.

Anc Sci Life. 2014 Oct-Dec;34(2):73-9. doi: 10.4103/0257-7941.153461.

7.

Combination of IFNα and poly-I:C reprograms bladder cancer microenvironment for enhanced CTL attraction.

Muthuswamy R, Wang L, Pitteroff J, Gingrich JR, Kalinski P.

J Immunother Cancer. 2015 Mar 24;3:6. doi: 10.1186/s40425-015-0050-8. eCollection 2015.

8.

IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients.

Wong JL, Muthuswamy R, Bartlett DL, Kalinski P.

Oncoimmunology. 2013 Sep 1;2(9):e26245. Epub 2013 Sep 12.

9.

Impaired migration of IgA-secreting cells to colon adenocarcinomas.

Muthuswamy RV, Sundström P, Börjesson L, Gustavsson B, Quiding-Järbrink M.

Cancer Immunol Immunother. 2013 Jun;62(6):989-97. doi: 10.1007/s00262-013-1410-1. Epub 2013 Apr 17.

PMID:
23591979
10.

Dendritic cells in cancer immunotherapy: vaccines and combination immunotherapies.

Kalinski P, Muthuswamy R, Urban J.

Expert Rev Vaccines. 2013 Mar;12(3):285-95. doi: 10.1586/erv.13.22. Review.

11.

The receptor for advanced glycation end products promotes pancreatic carcinogenesis and accumulation of myeloid-derived suppressor cells.

Vernon PJ, Loux TJ, Schapiro NE, Kang R, Muthuswamy R, Kalinski P, Tang D, Lotze MT, Zeh HJ 3rd.

J Immunol. 2013 Feb 1;190(3):1372-9. doi: 10.4049/jimmunol.1201151. Epub 2012 Dec 26.

12.

NF-κB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells.

Muthuswamy R, Berk E, Junecko BF, Zeh HJ, Zureikat AH, Normolle D, Luong TM, Reinhart TA, Bartlett DL, Kalinski P.

Cancer Res. 2012 Aug 1;72(15):3735-43. doi: 10.1158/0008-5472.CAN-11-4136. Epub 2012 May 16.

13.

Lymphocyte-polarized dendritic cells are highly effective in inducing tumor-specific CTLs.

Berk E, Muthuswamy R, Kalinski P.

Vaccine. 2012 Sep 21;30(43):6216-24. doi: 10.1016/j.vaccine.2012.04.077. Epub 2012 May 1.

14.

Pattern of neuropsychiatric illnesses in older age group population: an inpatient study report from Nepal.

Aich TK, Dhungana M, Muthuswamy R.

Indian J Psychiatry. 2012 Jan;54(1):23-31. doi: 10.4103/0019-5545.94641.

15.

Treg-mediated angiogenesis and tolerance is programmed by hypoxia in the tumor microenvironment.

Berk E, Muthuswamy R.

Immunotherapy. 2011 Dec;3(12):1429. No abstract available.

PMID:
22200066
16.

T-cell tolerance induced by non-Treg T-cell-derived TGF-β1.

Berk E, Muthuswamy R.

Immunotherapy. 2011 Dec;3(12):1428. No abstract available.

PMID:
22200065
17.

MKP-1 signaling translates innate signals into adaptive responses.

Berk E, Muthuswamy R.

Immunotherapy. 2011 Dec;3(12):1427-8. doi: 10.2217/imt.11.134. No abstract available.

PMID:
22091678
18.

Defective NF-κB signaling in metastatic head and neck cancer cells leads to enhanced apoptosis by double-stranded RNA.

Umemura N, Zhu J, Mburu YK, Forero A, Hsieh PN, Muthuswamy R, Kalinski P, Ferris RL, Sarkar SN.

Cancer Res. 2012 Jan 1;72(1):45-55. doi: 10.1158/0008-5472.CAN-11-1484. Epub 2011 Nov 4.

19.

PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment.

Obermajer N, Muthuswamy R, Odunsi K, Edwards RP, Kalinski P.

Cancer Res. 2011 Dec 15;71(24):7463-70. doi: 10.1158/0008-5472.CAN-11-2449. Epub 2011 Oct 24.

20.

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells.

Obermajer N, Muthuswamy R, Lesnock J, Edwards RP, Kalinski P.

Blood. 2011 Nov 17;118(20):5498-505. doi: 10.1182/blood-2011-07-365825. Epub 2011 Oct 4.

21.

PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive T cells.

Muthuswamy R, Mueller-Berghaus J, Haberkorn U, Reinhart TA, Schadendorf D, Kalinski P.

Blood. 2010 Sep 2;116(9):1454-9. doi: 10.1182/blood-2009-12-258038. Epub 2010 May 24.

22.

Independent regulation of chemokine responsiveness and cytolytic function versus CD8+ T cell expansion by dendritic cells.

Watchmaker PB, Berk E, Muthuswamy R, Mailliard RB, Urban JA, Kirkwood JM, Kalinski P.

J Immunol. 2010 Jan 15;184(2):591-7. doi: 10.4049/jimmunol.0902062. Epub 2009 Dec 16.

23.

Generation of stable Th1/CTL-, Th2-, and Th17-inducing human dendritic cells.

Kalinski P, Wieckowski E, Muthuswamy R, de Jong E.

Methods Mol Biol. 2010;595:117-33. doi: 10.1007/978-1-60761-421-0_7.

24.

IL-4 suppresses very late antigen-4 expression which is required for therapeutic Th1 T-cell trafficking into tumors.

Sasaki K, Pardee AD, Qu Y, Zhao X, Ueda R, Kohanbash G, Bailey LM, Okada H, Muthuswamy R, Kalinski P, Basse PH, Falo LD, Storkus WJ.

J Immunother. 2009 Oct;32(8):793-802. doi: 10.1097/CJI.0b013e3181acec1e.

25.

Dendritic cell-based therapeutic cancer vaccines: what we have and what we need.

Kalinski P, Urban J, Narang R, Berk E, Wieckowski E, Muthuswamy R.

Future Oncol. 2009 Apr;5(3):379-90. doi: 10.2217/fon.09.6. Review.

26.

Effective immunotherapy against murine gliomas using type 1 polarizing dendritic cells--significant roles of CXCL10.

Fujita M, Zhu X, Ueda R, Sasaki K, Kohanbash G, Kastenhuber ER, McDonald HA, Gibson GA, Watkins SC, Muthuswamy R, Kalinski P, Okada H.

Cancer Res. 2009 Feb 15;69(4):1587-95. doi: 10.1158/0008-5472.CAN-08-2915. Epub 2009 Feb 3. Erratum in: Cancer Res. 2010 Aug 15;70(16):6683.

27.

Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation.

Muthuswamy R, Urban J, Lee JJ, Reinhart TA, Bartlett D, Kalinski P.

Cancer Res. 2008 Jul 15;68(14):5972-8. doi: 10.1158/0008-5472.CAN-07-6818.

28.

Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia.

Lee JJ, Foon KA, Mailliard RB, Muthuswamy R, Kalinski P.

J Leukoc Biol. 2008 Jul;84(1):319-25. doi: 10.1189/jlb.1107737. Epub 2008 Apr 21.

29.

Helper function of memory CD8+ T cells: heterologous CD8+ T cells support the induction of therapeutic cancer immunity.

Nakamura Y, Watchmaker P, Urban J, Sheridan B, Giermasz A, Nishimura F, Sasaki K, Cumberland R, Muthuswamy R, Mailliard RB, Larregina AT, Falo LD, Gooding W, Storkus WJ, Okada H, Hendricks RL, Kalinski P.

Cancer Res. 2007 Oct 15;67(20):10012-8.

30.

Helper roles of NK and CD8+ T cells in the induction of tumor immunity. Polarized dendritic cells as cancer vaccines.

Kalinski P, Nakamura Y, Watchmaker P, Giermasz A, Muthuswamy R, Mailliard RB.

Immunol Res. 2006;36(1-3):137-46. Review.

PMID:
17337774
31.

Mechanisms for human cytomegalovirus-induced cytoplasmic p53 sequestration in endothelial cells.

Utama B, Shen YH, Mitchell BM, Makagiansar IT, Gan Y, Muthuswamy R, Duraisamy S, Martin D, Wang X, Zhang MX, Wang J, Wang J, Vercellotti GM, Gu W, Wang XL.

J Cell Sci. 2006 Jun 15;119(Pt 12):2457-67. Epub 2006 May 23.

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