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Items: 10

1.

New insights regarding epithelial Na+ channel regulation and its role in the kidney, immune system and vasculature.

Mutchler SM, Kleyman TR.

Curr Opin Nephrol Hypertens. 2019 Mar;28(2):113-119. doi: 10.1097/MNH.0000000000000479.

PMID:
30585851
2.

Pore-lining residues of MEC-4 and MEC-10 channel subunits tune the Caenorhabditis elegans degenerin channel's response to shear stress.

Shi S, Mutchler SM, Blobner BM, Kashlan OB, Kleyman TR.

J Biol Chem. 2018 Jul 6;293(27):10757-10766. doi: 10.1074/jbc.RA118.002499. Epub 2018 May 9.

PMID:
29743244
3.

Increased myoendothelial feedback is associated with increased connexin37 and IK1 channel expression in mesenteric arteries of diet-induced hyperhomocysteinemic mice.

Looft-Wilson RC, Goodell CR, Mutch CA, Mutchler SM, Miller KL, Guraya M.

Microcirculation. 2017 Nov;24(8). doi: 10.1111/micc.12398.

PMID:
28857417
4.

Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors.

Sangwung P, Zhou G, Lu Y, Liao X, Wang B, Mutchler SM, Miller M, Chance MR, Straub AC, Jain MK.

Vasc Med. 2017 Oct;22(5):363-369. doi: 10.1177/1358863X17722211. Epub 2017 Aug 19.

5.

TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.

Rogers NM, Sharifi-Sanjani M, Yao M, Ghimire K, Bienes-Martinez R, Mutchler SM, Knupp HE, Baust J, Novelli EM, Ross M, St Croix C, Kutten JC, Czajka CA, Sembrat JC, Rojas M, Labrousse-Arias D, Bachman TN, Vanderpool RR, Zuckerbraun BS, Champion HC, Mora AL, Straub AC, Bilonick RA, Calzada MJ, Isenberg JS.

Cardiovasc Res. 2017 Jan;113(1):15-29. doi: 10.1093/cvr/cvw218. Epub 2016 Oct 13.

6.

Compartmentalized nitric oxide signaling in the resistance vasculature.

Mutchler SM, Straub AC.

Nitric Oxide. 2015 Sep 15;49:8-15. doi: 10.1016/j.niox.2015.05.003. Epub 2015 May 28. Review.

7.

Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.

Rahaman MM, Reinders FG, Koes D, Nguyen AT, Mutchler SM, Sparacino-Watkins C, Alvarez RA, Miller MP, Cheng D, Chen BB, Jackson EK, Camacho CJ, Straub AC.

J Biol Chem. 2015 Jul 3;290(27):16861-72. doi: 10.1074/jbc.M114.629964. Epub 2015 May 22.

8.

A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.

Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE.

Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824.

9.

Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction.

Straub AC, Butcher JT, Billaud M, Mutchler SM, Artamonov MV, Nguyen AT, Johnson T, Best AK, Miller MP, Palmer LA, Columbus L, Somlyo AV, Le TH, Isakson BE.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2594-600. doi: 10.1161/ATVBAHA.114.303974. Epub 2014 Oct 2.

10.

Alpha(1)-adrenergic-mediated eNOS phosphorylation in intact arteries.

Looft-Wilson RC, Todd SE, Araj CA, Mutchler SM, Goodell CA.

Vascul Pharmacol. 2013 Jan;58(1-2):112-7. doi: 10.1016/j.vph.2012.09.003. Epub 2012 Sep 13.

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