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Items: 1 to 50 of 161

1.

Correcting tyrosinaemia via a point mutation.

Musunuru K.

Nat Biomed Eng. 2020 Jan;4(1):14-15. doi: 10.1038/s41551-019-0489-x. No abstract available.

PMID:
31937937
2.

Why Human Embryo Editing Should Be Banned.

Musunuru K.

CRISPR J. 2019 Dec;2(6):356-358. doi: 10.1089/crispr.2019.29078.kmu. No abstract available.

PMID:
31860349
3.

Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes.

McDermott-Roe C, Lv W, Maximova T, Wada S, Bukowy J, Marquez M, Lai S, Shehu A, Benjamin I, Geurts A, Musunuru K.

JCI Insight. 2019 Nov 14;4(22). pii: 128799. doi: 10.1172/jci.insight.128799.

4.

Angiopoietin-Like 3: From Discovery to Therapeutic Gene Editing.

Wang X, Musunuru K.

JACC Basic Transl Sci. 2019 Oct 28;4(6):755-762. doi: 10.1016/j.jacbts.2019.05.008. eCollection 2019 Oct. Review.

5.

Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.

Patel N, Russell GK, Musunuru K, Gutierrez OM, Halade G, Kain V, Lv W, Prabhu SD, Margulies KB, Cappola TP, Arora G, Wang TJ, Arora P.

Circ Res. 2019 Nov 8;125(11):957-968. doi: 10.1161/CIRCRESAHA.119.315026. Epub 2019 Oct 6.

PMID:
31588864
6.

The clinical application of gene editing: ethical and social issues.

Ormond KE, Bombard Y, Bonham VL, Hoffman-Andrews L, Howard H, Isasi R, Musunuru K, Riggan KA, Michie M, Allyse M.

Per Med. 2019 Jul;16(4):337-350. doi: 10.2217/pme-2018-0155. Epub 2019 Jul 23.

PMID:
31331245
7.

From Hypertrophy to Heart Failure: What Is New in Genetic Cardiomyopathies.

Reza N, Musunuru K, Owens AT.

Curr Heart Fail Rep. 2019 Oct;16(5):157-167. doi: 10.1007/s11897-019-00435-0. Review.

PMID:
31243690
8.

Tunable and Reversible Substrate Stiffness Reveals a Dynamic Mechanosensitivity of Cardiomyocytes.

Corbin EA, Vite A, Peyster EG, Bhoopalam M, Brandimarto J, Wang X, Bennett AI, Clark AT, Cheng X, Turner KT, Musunuru K, Margulies KB.

ACS Appl Mater Interfaces. 2019 Jun 12;11(23):20603-20614. doi: 10.1021/acsami.9b02446. Epub 2019 May 30.

PMID:
31074953
9.

Cardioprotective Effects of MTSS1 Enhancer Variants.

Morley MP, Wang X, Hu R, Brandimarto J, Tucker NR, Felix JF, Smith NL, van der Harst P, Ellinor PT, Margulies KB, Musunuru K, Cappola TP.

Circulation. 2019 Apr 23;139(17):2073-2076. doi: 10.1161/CIRCULATIONAHA.118.037939. No abstract available.

PMID:
31070942
10.

In utero gene editing for monogenic lung disease.

Alapati D, Zacharias WJ, Hartman HA, Rossidis AC, Stratigis JD, Ahn NJ, Coons B, Zhou S, Li H, Singh K, Katzen J, Tomer Y, Chadwick AC, Musunuru K, Beers MF, Morrisey EE, Peranteau WH.

Sci Transl Med. 2019 Apr 17;11(488). pii: eaav8375. doi: 10.1126/scitranslmed.aav8375.

PMID:
30996081
11.

What do we do now?: Responding to claims of germline gene editing in humans.

Allyse M, Bombard Y, Isasi R, Michie M, Musunuru K, Ormond KE.

Genet Med. 2019 Oct;21(10):2181-2183. doi: 10.1038/s41436-019-0492-3. Epub 2019 Mar 27. No abstract available.

PMID:
30914827
12.

Genetics of Common, Complex Coronary Artery Disease.

Musunuru K, Kathiresan S.

Cell. 2019 Mar 21;177(1):132-145. doi: 10.1016/j.cell.2019.02.015. Review.

PMID:
30901535
13.

Medical Misinformation: Vet the Message!

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

J Cardiovasc Pharmacol. 2019 Feb;73(2):61-62. doi: 10.1097/FJC.0000000000000648. No abstract available.

PMID:
30730472
14.

Medical misinformation: Vet the message!

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Heart Rhythm. 2019 Mar;16(3):332-333. doi: 10.1016/j.hrthm.2018.12.030. Epub 2019 Jan 28. No abstract available.

15.

Medical Misinformation - Vet the Message!

Hill JA, Agewal S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Sweitzer NK, Timmis A, Vrints C.

Anatol J Cardiol. 2019 Feb;21(2):58-59. doi: 10.14744/AnatolJCardiol.2019.22. No abstract available.

16.

Medical Misinformation: Vet the Message!

Hill JA; following HEART Group Signatories, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Eur Heart J. 2019 Feb 1;40(5):404-405. doi: 10.1093/eurheartj/ehz009. No abstract available.

17.

Medical misinformation: vet the message!

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Eur Heart J Qual Care Clin Outcomes. 2019 Apr 1;5(2):83-84. doi: 10.1093/ehjqcco/qcy057. No abstract available.

18.

Medical misinformation: vet the message!

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Eur Heart J Cardiovasc Pharmacother. 2019 Apr 1;5(2):62-63. doi: 10.1093/ehjcvp/pvz001. No abstract available.

19.

Medical misinformation: vet the message!

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Cardiovasc Res. 2019 Jan 28. doi: 10.1093/cvr/cvz007. [Epub ahead of print] No abstract available.

PMID:
30689762
20.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Circulation. 2019 Jan 29;139(5):571-572. doi: 10.1161/CIRCULATIONAHA.118.039193. No abstract available.

PMID:
30689419
21.

Medical Misinformation: Vet the Message!

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol C, Grines C, Gropler RJ, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis AD, Vrints CJ.

Circulation. 2019 Jan 28. doi: 10.1161/CIRCULATIONAHA.118.039193. [Epub ahead of print] No abstract available.

PMID:
30688522
22.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Circ Cardiovasc Interv. 2019 Feb;12(2):e007796. doi: 10.1161/CIRCINTERVENTIONS.119.007796. No abstract available.

PMID:
30688520
23.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol C, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C; All authors are HEART Group Signatories.

Circ Cardiovasc Qual Outcomes. 2019 Feb;12(2):e005496. doi: 10.1161/CIRCOUTCOMES.119.005496. No abstract available.

PMID:
30688519
24.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Circ Cardiovasc Imaging. 2019 Feb;12(2):e008809. doi: 10.1161/CIRCIMAGING.118.008809. No abstract available.

PMID:
30688516
25.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Circ Genom Precis Med. 2019 Feb;12(2):e002439. doi: 10.1161/CIRCGEN.118.002439. No abstract available.

PMID:
30688515
26.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C; All authors are HEART Group Signatories.

Circ Heart Fail. 2019 Feb;12(2):e005869. doi: 10.1161/CIRCHEARTFAILURE.119.005869. No abstract available.

PMID:
30688079
27.

Medical Misinformation.

Hill JA, Agewall S, Baranchuk A, Booz GW, Borer JS, Camici PG, Chen PS, Dominiczak AF, Erol Ç, Grines CL, Gropler R, Guzik TJ, Heinemann MK, Iskandrian AE, Knight BP, London B, Lüscher TF, Metra M, Musunuru K, Nallamothu BK, Natale A, Saksena S, Picard MH, Rao SV, Remme WJ, Rosenson RS, Sweitzer NK, Timmis A, Vrints C.

Hypertension. 2019 Mar;73(3):506-507. doi: 10.1161/HYPERTENSIONAHA.118.12518. No abstract available.

PMID:
30686083
28.

Scientists on the Spot: The future of genome editing in cardiovascular medicine.

Stellos K, Musunuru K.

Cardiovasc Res. 2019 Feb 1;115(2):e20-e21. doi: 10.1093/cvr/cvy302. No abstract available.

PMID:
30668681
29.

Challenges and advances of CRISPR-Cas9 genome editing in therapeutics.

Stellos K, Musunuru K.

Cardiovasc Res. 2019 Feb 1;115(2):e12-e14. doi: 10.1093/cvr/cvy300. No abstract available.

PMID:
30668679
30.

Functional Annotation of TNNT2 Variants of Uncertain Significance With Genome-Edited Cardiomyocytes.

Lv W, Qiao L, Petrenko N, Li W, Owens AT, McDermott-Roe C, Musunuru K.

Circulation. 2018 Dec 11;138(24):2852-2854. doi: 10.1161/CIRCULATIONAHA.118.035028. No abstract available.

31.

Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells.

Nagiec MM, Duvall JR, Skepner AP, Howe EA, Bastien J, Comer E, Marie JC, Johnston SE, Negri J, Eichhorn M, Vantourout J, Clish C, Musunuru K, Foley M, Perez JR, Palmer MAJ.

Medchemcomm. 2018 Sep 14;9(11):1831-1842. doi: 10.1039/c8md00297e. eCollection 2018 Nov 1.

32.

Confirmation of Causal rs9349379- PHACTR1 Expression Quantitative Trait Locus in Human-Induced Pluripotent Stem Cell Endothelial Cells.

Wang X, Musunuru K.

Circ Genom Precis Med. 2018 Oct;11(10):e002327. doi: 10.1161/CIRCGEN.118.002327. No abstract available.

33.

In utero CRISPR-mediated therapeutic editing of metabolic genes.

Rossidis AC, Stratigis JD, Chadwick AC, Hartman HA, Ahn NJ, Li H, Singh K, Coons BE, Li L, Lv W, Zoltick PW, Alapati D, Zacharias W, Jain R, Morrisey EE, Musunuru K, Peranteau WH.

Nat Med. 2018 Oct;24(10):1513-1518. doi: 10.1038/s41591-018-0184-6. Epub 2018 Oct 8.

34.

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

Small KS, Todorčević M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Vinuela A, Tsai PC, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris AP, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K, Lusis AJ, Cox RD, Karpe F, McCarthy MI.

Nat Genet. 2018 Sep;50(9):1342. doi: 10.1038/s41588-018-0180-2.

PMID:
30087441
35.
36.

Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association.

Musunuru K, Sheikh F, Gupta RM, Houser SR, Maher KO, Milan DJ, Terzic A, Wu JC; American Heart Association Council on Functional Genomics and Translational Biology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular and Stroke Nursing.

Circ Genom Precis Med. 2018 Jan;11(1):e000043. doi: 10.1161/HCG.0000000000000043. Epub 2018 Jan 12. Review.

37.

Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells.

Li S, Li M, Liu X, Yang Y, Wei Y, Chen Y, Qiu Y, Zhou T, Feng Z, Ma D, Fang J, Ying H, Wang H, Musunuru K, Shao Z, Zhao Y, Ding Q.

Stem Cell Reports. 2018 Jul 10;11(1):22-31. doi: 10.1016/j.stemcr.2018.05.001. Epub 2018 May 31.

38.

Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association.

Musunuru K, Arora P, Cooke JP, Ferguson JF, Hershberger RE, Hickey KT, Lee JM, Lima JAC, Loscalzo J, Pereira NL, Russell MW, Shah SH, Sheikh F, Wang TJ, MacRae CA; American Heart Association Council on Genomic and Precision Medicine; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; Council on Peripheral Vascular Disease; Council on Quality of Care and Outcomes Research; and Stroke Council.

Circ Genom Precis Med. 2018 Jun;11(6):e000046. doi: 10.1161/HCG.0000000000000046. Review.

39.

How genome editing could be used in the treatment of cardiovascular diseases.

Musunuru K.

Per Med. 2018 Mar;15(2):67-69. doi: 10.2217/pme-2017-0078. Epub 2018 Feb 2. No abstract available.

40.

Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.

Musunuru K, Bernstein D, Cole FS, Khokha MK, Lee FS, Lin S, McDonald TV, Moskowitz IP, Quertermous T, Sankaran VG, Schwartz DA, Silverman EK, Zhou X, Hasan AAK, Luo XJ.

Circ Genom Precis Med. 2018 Apr;11(4):e002178. doi: 10.1161/CIRCGEN.118.002178. Review.

41.

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

Small KS, Todorčević M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Viñuela A, Tsai PC, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris AP, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K, Lusis AJ, Cox RD, Karpe F, McCarthy MI.

Nat Genet. 2018 Apr;50(4):572-580. doi: 10.1038/s41588-018-0088-x. Epub 2018 Apr 9. Erratum in: Nat Genet. 2018 Sep;50(9):1342.

42.

Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3.

Chadwick AC, Evitt NH, Lv W, Musunuru K.

Circulation. 2018 Feb 27;137(9):975-977. doi: 10.1161/CIRCULATIONAHA.117.031335. No abstract available.

43.

Stem cell modeling of lipid genetics.

Musunuru K.

Curr Opin Lipidol. 2018 Apr;29(2):151-155. doi: 10.1097/MOL.0000000000000490. Review.

PMID:
29351105
44.

Turning up the Heat with Therapeutic Epigenome Editing.

Zezulin A, Musunuru K.

Cell Stem Cell. 2018 Jan 4;22(1):10-11. doi: 10.1016/j.stem.2017.12.013.

45.

Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.

Musunuru K.

J Am Coll Cardiol. 2017 Dec 5;70(22):2808-2821. doi: 10.1016/j.jacc.2017.10.002. Review.

46.

Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol.

Xu YX, Redon V, Yu H, Querbes W, Pirruccello J, Liebow A, Deik A, Trindade K, Wang X, Musunuru K, Clish CB, Cowan C, Fizgerald K, Rader D, Kathiresan S.

Atherosclerosis. 2018 Jan;268:196-206. doi: 10.1016/j.atherosclerosis.2017.08.031. Epub 2017 Sep 21.

47.

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.

Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ.

Dev Cell. 2017 Nov 6;43(3):318-331.e5. doi: 10.1016/j.devcel.2017.09.026. Epub 2017 Oct 26.

48.

Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice.

Wang X, Raghavan A, Peters DT, Pashos EE, Rader DJ, Musunuru K.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):76-82. doi: 10.1161/ATVBAHA.117.310103. Epub 2017 Nov 2.

49.

Exome-wide association study of plasma lipids in >300,000 individuals.

Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrieres J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Jarvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee F, Khera AV, Klarin D, Koistinen HA, Kooner JS, Kooperberg C, Kuulasmaa K, Kuusisto J, Laakso M, Lakka T, Langenberg C, Langsted A, Launer LJ, Lauritzen T, Liewald DCM, Lin LA, Linneberg A, Loos RJF, Lu Y, Lu X, Mägi R, Malarstig A, Manichaikul A, Manning AK, Mäntyselkä P, Marouli E, Masca NGD, Maschio A, Meigs JB, Melander O, Metspalu A, Morris AP, Morrison AC, Mulas A, Müller-Nurasyid M, Munroe PB, Neville MJ, Nielsen JB, Nielsen SF, Nordestgaard BG, Ordovas JM, Mehran R, O'Donnell CJ, Orho-Melander M, Molony CM, Muntendam P, Padmanabhan S, Palmer CNA, Pasko D, Patel AP, Pedersen O, Perola M, Peters A, Pisinger C, Pistis G, Polasek O, Poulter N, Psaty BM, Rader DJ, Rasheed A, Rauramaa R, Reilly DF, Reiner AP, Renström F, Rich SS, Ridker PM, Rioux JD, Robertson NR, Roden DM, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sanna S, Sattar N, Schmidt EM, Scott RA, Sever P, Sevilla RS, Shaffer CM, Sim X, Sivapalaratnam S, Small KS, Smith AV, Smith BH, Somayajula S, Southam L, Spector TD, Speliotes EK, Starr JM, Stirrups KE, Stitziel N, Strauch K, Stringham HM, Surendran P, Tada H, Tall AR, Tang H, Tardif JC, Taylor KD, Trompet S, Tsao PS, Tuomilehto J, Tybjaerg-Hansen A, van Zuydam NR, Varbo A, Varga TV, Virtamo J, Waldenberger M, Wang N, Wareham NJ, Warren HR, Weeke PE, Weinstock J, Wessel J, Wilson JG, Wilson PWF, Xu M, Yaghootkar H, Young R, Zeggini E, Zhang H, Zheng NS, Zhang W, Zhang Y, Zhou W, Zhou Y, Zoledziewska M; Charge Diabetes Working Group; EPIC-InterAct Consortium; EPIC-CVD Consortium; GOLD Consortium; VA Million Veteran Program, Howson JMM, Danesh J, McCarthy MI, Cowan CA, Abecasis G, Deloukas P, Musunuru K, Willer CJ, Kathiresan S.

Nat Genet. 2017 Dec;49(12):1758-1766. doi: 10.1038/ng.3977. Epub 2017 Oct 30.

50.

Reply: Loss-of-Function Mutations to Estimate Pharmacological ANGPTL3 Inhibition.

Stitziel NO, Musunuru K, Kathiresan S.

J Am Coll Cardiol. 2017 Oct 17;70(16):2099-2100. doi: 10.1016/j.jacc.2017.07.794. No abstract available.

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