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Items: 25

1.

AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway.

Petti C, Vegetti C, Molla A, Bersani I, Cleris L, Mustard KJ, Formelli F, Hardie GD, Sensi M, Anichini A.

Melanoma Res. 2012 Oct;22(5):341-50. doi: 10.1097/CMR.0b013e3283544929.

PMID:
22588166
2.

The ancient drug salicylate directly activates AMP-activated protein kinase.

Hawley SA, Fullerton MD, Ross FA, Schertzer JD, Chevtzoff C, Walker KJ, Peggie MW, Zibrova D, Green KA, Mustard KJ, Kemp BE, Sakamoto K, Steinberg GR, Hardie DG.

Science. 2012 May 18;336(6083):918-22. doi: 10.1126/science.1215327. Epub 2012 Apr 19.

3.

Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet.

Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PA, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW.

Diabetologia. 2011 Sep;54(9):2392-403. doi: 10.1007/s00125-011-2205-6. Epub 2011 Jun 11.

4.

Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

Fogarty S, Hawley SA, Green KA, Saner N, Mustard KJ, Hardie DG.

Biochem J. 2010 Jan 27;426(1):109-18. doi: 10.1042/BJ20091372.

5.

AMP-activated protein kinase and hypoxic pulmonary vasoconstriction.

Robertson TP, Mustard KJ, Lewis TH, Clark JH, Wyatt CN, Blanco EA, Peers C, Hardie DG, Evans AM.

Eur J Pharmacol. 2008 Oct 24;595(1-3):39-43. doi: 10.1016/j.ejphar.2008.07.035. Epub 2008 Jul 30.

6.

Normal hypertrophy accompanied by phosphoryation and activation of AMP-activated protein kinase alpha1 following overload in LKB1 knockout mice.

McGee SL, Mustard KJ, Hardie DG, Baar K.

J Physiol. 2008 Mar 15;586(6):1731-41. doi: 10.1113/jphysiol.2007.143685. Epub 2008 Jan 17.

7.

Age-related HMG-CoA reductase deregulation depends on ROS-induced p38 activation.

Pallottini V, Martini C, Cavallini G, Bergamini E, Mustard KJ, Hardie DG, Trentalance A.

Mech Ageing Dev. 2007 Nov-Dec;128(11-12):688-95. Epub 2007 Oct 16.

PMID:
18031790
8.

Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.

Woollhead AM, Sivagnanasundaram J, Kalsi KK, Pucovsky V, Pellatt LJ, Scott JW, Mustard KJ, Hardie DG, Baines DL.

Br J Pharmacol. 2007 Aug;151(8):1204-15. Epub 2007 Jul 2.

9.

5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men.

Cuthbertson DJ, Babraj JA, Mustard KJ, Towler MC, Green KA, Wackerhage H, Leese GP, Baar K, Thomason-Hughes M, Sutherland C, Hardie DG, Rennie MJ.

Diabetes. 2007 Aug;56(8):2078-84. Epub 2007 May 18.

10.

Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis.

Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie DG, Young LH, Shulman GI.

Cell Metab. 2007 Feb;5(2):151-6.

11.

AMP-activated protein kinase mediates carotid body excitation by hypoxia.

Wyatt CN, Mustard KJ, Pearson SA, Dallas ML, Atkinson L, Kumar P, Peers C, Hardie DG, Evans AM.

J Biol Chem. 2007 Mar 16;282(11):8092-8. Epub 2006 Dec 19.

12.

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

Tamás P, Hawley SA, Clarke RG, Mustard KJ, Green K, Hardie DG, Cantrell DA.

J Exp Med. 2006 Jul 10;203(7):1665-70. Epub 2006 Jul 3.

13.

Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to pulmonary artery constriction?

Evans AM, Mustard KJ, Wyatt CN, Dipp M, Kinnear NP, Hardie DG.

Adv Exp Med Biol. 2006;580:147-54; discussion 351-9. No abstract available.

PMID:
16683711
14.

Intramyocellular lipid content and molecular adaptations in response to a 1-week high-fat diet.

Schrauwen-Hinderling VB, Kooi ME, Hesselink MK, Moonen-Kornips E, Schaart G, Mustard KJ, Hardie DG, Saris WH, Nicolay K, Schrauwen P.

Obes Res. 2005 Dec;13(12):2088-94.

15.

Involvement of AMP-activated protein kinase in fat depot-specific metabolic changes during starvation.

Sponarova J, Mustard KJ, Horakova O, Flachs P, Rossmeisl M, Brauner P, Bardova K, Thomason-Hughes M, Braunerova R, Janovska P, Hardie DG, Kopecky J.

FEBS Lett. 2005 Nov 7;579(27):6105-10. Epub 2005 Oct 7.

16.

Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells?

Evans AM, Mustard KJ, Wyatt CN, Peers C, Dipp M, Kumar P, Kinnear NP, Hardie DG.

J Biol Chem. 2005 Dec 16;280(50):41504-11. Epub 2005 Sep 30. Erratum in: J Biol Chem. 2006 Jul 21;281(29):20660.

17.

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.

Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG.

Cell Metab. 2005 Jul;2(1):9-19.

18.

Possible involvement of AMP-activated protein kinase in obesity resistance induced by respiratory uncoupling in white fat.

Matejkova O, Mustard KJ, Sponarova J, Flachs P, Rossmeisl M, Miksik I, Thomason-Hughes M, Grahame Hardie D, Kopecky J.

FEBS Lett. 2004 Jul 2;569(1-3):245-8.

19.

AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes.

Højlund K, Mustard KJ, Staehr P, Hardie DG, Beck-Nielsen H, Richter EA, Wojtaszewski JF.

Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E239-44. Epub 2003 Oct 7.

20.

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG.

J Biol. 2003;2(4):28. doi: 10.1186/1475-4924-2-28. Epub 2003 Sep 24.

21.

Fibrates and medroxyprogesterone acetate induce apoptosis of primary Burkitt's lymphoma cells and cell lines: potential for applying old drugs to a new disease.

Fenton SL, Luong QT, Sarafeim A, Mustard KJ, Pound J, Desmond JC, Gordon J, Drayson MT, Bunce CM.

Leukemia. 2003 Mar;17(3):568-75.

PMID:
12646946
22.

Long-term regulation of AMP-activated protein kinase and acetyl-CoA carboxylase in skeletal muscle.

Winder WW, Hardie DG, Mustard KJ, Greenwood LJ, Paxton BE, Park SH, Rubink DS, Taylor EB.

Biochem Soc Trans. 2003 Feb;31(Pt 1):182-5. Review.

PMID:
12546681
23.

Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle.

Park SH, Paulsen SR, Gammon SR, Mustard KJ, Hardie DG, Winder WW.

J Appl Physiol (1985). 2002 Dec;93(6):2081-8.

24.

5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle.

Nielsen JN, Mustard KJ, Graham DA, Yu H, MacDonald CS, Pilegaard H, Goodyear LJ, Hardie DG, Richter EA, Wojtaszewski JF.

J Appl Physiol (1985). 2003 Feb;94(2):631-41. Epub 2002 Oct 11.

25.

Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles.

Durante PE, Mustard KJ, Park SH, Winder WW, Hardie DG.

Am J Physiol Endocrinol Metab. 2002 Jul;283(1):E178-86.

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