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Items: 8


Avoidance of Trinucleotide Corresponding to Consensus Protospacer Adjacent Motif Controls the Efficiency of Prespacer Selection during Primed Adaptation.

Musharova O, Vyhovskyi D, Medvedeva S, Guzina J, Zhitnyuk Y, Djordjevic M, Severinov K, Savitskaya E.

MBio. 2018 Dec 4;9(6). pii: e02169-18. doi: 10.1128/mBio.02169-18.


Primed CRISPR adaptation in Escherichia coli cells does not depend on conformational changes in the Cascade effector complex detected in Vitro.

Krivoy A, Rutkauskas M, Kuznedelov K, Musharova O, Rouillon C, Severinov K, Seidel R.

Nucleic Acids Res. 2018 May 4;46(8):4087-4098. doi: 10.1093/nar/gky219.


Spacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation.

Musharova O, Klimuk E, Datsenko KA, Metlitskaya A, Logacheva M, Semenova E, Severinov K, Savitskaya E.

Nucleic Acids Res. 2017 Apr 7;45(6):3297-3307. doi: 10.1093/nar/gkx097.


Diversity of CRISPR-Cas-Mediated Mechanisms of Adaptive Immunity in Prokaryotes and Their Application in Biotechnology.

Savitskaya EE, Musharova OS, Severinov KV.

Biochemistry (Mosc). 2016 Jul;81(7):653-61. doi: 10.1134/S0006297916070026. Review.


Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type I-E CRISPR-Cas interfering complex.

Semenova E, Savitskaya E, Musharova O, Strotskaya A, Vorontsova D, Datsenko KA, Logacheva MD, Severinov K.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7626-31. doi: 10.1073/pnas.1602639113. Epub 2016 Jun 20.


CRISPR interference and priming varies with individual spacer sequences.

Xue C, Seetharam AS, Musharova O, Severinov K, Brouns SJ, Severin AJ, Sashital DG.

Nucleic Acids Res. 2015 Dec 15;43(22):10831-47. doi: 10.1093/nar/gkv1259. Epub 2015 Nov 19.


[Transcription factor Kaiso does not interact with hydroxymethylated DNA within CTGCNA sequence context].

Zhenilo SV, Musharova OS, Pokhorchuk EB.

Mol Biol (Mosk). 2013 May-Jun;47(3):522-5. Russian. No abstract available.


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