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Time to First Cigarette: A Potential Clinical Screening Tool for Nicotine Dependence.

Branstetter SA, Muscat JE, Mercincavage M.

J Addict Med. 2020 Jan 14. doi: 10.1097/ADM.0000000000000610. [Epub ahead of print]


Reducing the Nicotine Content of Cigarettes: Effects in Smokers With Mental Health Conditions and Socioeconomic Disadvantages.

Tidey JW, Muscat JE, Foulds J, Evins AE, Gaalema DE, Denlinger-Apte RL.

Nicotine Tob Res. 2019 Dec 23;21(Suppl 1):S26-S28. doi: 10.1093/ntr/ntz118.


Time to first cigarette of the day and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in adult regular and non-daily smokers: (NHANES) 2007-10.

Branstetter SA, Nye RT, Muscat JE.

Regul Toxicol Pharmacol. 2019 Nov;108:104454. doi: 10.1016/j.yrtph.2019.104454. Epub 2019 Aug 27.


Socioeconomic differences in nicotine exposure and dependence in adult daily smokers.

Chen A, Machiorlatti M, Krebs NM, Muscat JE.

BMC Public Health. 2019 Apr 3;19(1):375. doi: 10.1186/s12889-019-6694-4.


Pharmacokinetic Profile of Spectrum Reduced Nicotine Cigarettes.

Kamens HM, Silva CP, Nye RT, Miller CN, Singh N, Sipko J, Trushin N, Sun D, Branstetter SA, Muscat JE, Richie JP, Foulds J.

Nicotine Tob Res. 2020 Feb 6;22(2):273-279. doi: 10.1093/ntr/ntz045.


Effect of Cigarette Rod Length on Smokers Switching to SPECTRUM Cigarettes.

Hrabovsky SM, Midya V, Lester C, Veldheer S, Yingst JM, Allen SI, Krebs NM, Liao J, Reinhart L, Modesto J, Evins AE, Richie JP Jr, Muscat JE, Horn K, Foulds J.

Am J Health Behav. 2019 Mar 1;43(2):380-392. doi: 10.5993/AJHB.43.2.14.


Nicotine dependence as an independent risk factor for atherosclerosis in the National Lung Screening Trial.

Zhu J, Nelson K, Toth J, Muscat JE.

BMC Public Health. 2019 Jan 22;19(1):103. doi: 10.1186/s12889-019-6419-8.


Differential transcriptional changes in human alveolar epithelial A549 cells exposed to airborne PM2.5 collected from Shanghai, China.

Lei X, Muscat JE, Huang Z, Chen C, Xiu G, Chen J.

Environ Sci Pollut Res Int. 2018 Nov;25(33):33656-33666. doi: 10.1007/s11356-018-3090-z. Epub 2018 Oct 1.


Clinical trial recruitment of adult African American smokers from economically disadvantaged urban communities.

Horn K, Kuprewicz RM, Patterson K, Kaufman J, Murugesan U, Martinez DJ, Krebs NM, Muscat JE.

J Ethn Subst Abuse. 2020 Jan-Mar;19(1):133-150. doi: 10.1080/15332640.2018.1489746. Epub 2018 Sep 28.


The Effect of Price on the Consumption of Reduced Nicotine Cigarettes.

Branstetter SA, Nye R, Sipko JJ, Muscat JE.

Nicotine Tob Res. 2019 Jun 21;21(7):955-961. doi: 10.1093/ntr/nty169.


Cigarette Management System: An operating procedures guide to obtaining and managing investigational tobacco products for regulatory science research.

Kazi A, Fazzi A, Krebs NM, Merchlinski AJ, Kline B, Veldheer S, Richie JP Jr, Foulds J, Lane T, Donny EC, Muscat JE.

Contemp Clin Trials Commun. 2018 May 5;11:69-74. doi: 10.1016/j.conctc.2018.05.006. eCollection 2018 Sep.


Nicotine metabolite ratio predicts smoking topography: The Pennsylvania Adult Smoking Study.

Chen A, Krebs NM, Zhu J, Muscat JE.

Drug Alcohol Depend. 2018 Sep 1;190:89-93. doi: 10.1016/j.drugalcdep.2018.06.003. Epub 2018 Jul 4.


Characteristics of Adult Cigarette Smokers Who "Relight" and the Effects of Exposure to Tobacco Smoke Constituents.

Allen SI, Wasserman E, Veldheer S, Yingst J, Hrabovsky S, Liao J, Krebs NM, Horn K, Reinhart L, Modesto J, Putt K, Evins AE, Muscat JE, Richie JP, Foulds J.

Nicotine Tob Res. 2019 Aug 19;21(9):1206-1212. doi: 10.1093/ntr/nty138.


Income as a moderator of psychological stress and nicotine dependence among adult smokers.

Hobkirk AL, Krebs NM, Muscat JE.

Addict Behav. 2018 Sep;84:215-223. doi: 10.1016/j.addbeh.2018.04.021. Epub 2018 Apr 27.


Differences in nicotine dependence, smoke exposure and consumer characteristics between smokers of machine-injected roll-your-own cigarettes and factory-made cigarettes.

Joseph S, Krebs NM, Zhu J, Wert Y, Goel R, Reilly SM, Sun D, Richie JP Jr, Nikiforov I, Cheriyath P, Muscat JE.

Drug Alcohol Depend. 2018 Jun 1;187:109-115. doi: 10.1016/j.drugalcdep.2018.01.039. Epub 2018 Apr 7.


Comparison of Biomarkers of Tobacco Exposure between Premium and Discount Brand Cigarette Smokers in the NHANES 2011-2012 Special Sample.

Wasserman EJ, Reilly SM, Goel R, Foulds J, Richie JP Jr, Muscat JE.

Cancer Epidemiol Biomarkers Prev. 2018 May;27(5):601-609. doi: 10.1158/1055-9965.EPI-17-0869. Epub 2018 Mar 6.


Ecological momentary assessment of smoking behaviors in native and converted intermittent smokers.

Stennett A, Krebs NM, Liao J, Richie JP Jr, Muscat JE.

Am J Addict. 2018 Mar;27(2):131-138. doi: 10.1111/ajad.12690.


Correction to Reduced nicotine content cigarettes in smokers of low socioeconomic status: study protocol for a randomized control trial.

Krebs NM, Allen SI, Veldheer S, Martinez DJ, Horn K, Livelsberger C, Modesto J, Kuprewicz R, Wilhelm A, Hrabovsky S, Kazi A, Fazzi A, Liao J, Zhu J, Wasserman E, Reilly SM, Reinhart L, Trushin N, Moyer RE, Bascom R, Foulds J, Richie JP Jr, Muscat JE.

Trials. 2017 Dec 15;18(1):598. doi: 10.1186/s13063-017-2356-y.


On meta- and mega-analyses for gene-environment interactions.

Huang J, Liu Y, Vitale S, Penning TM, Whitehead AS, Blair IA, Vachani A, Clapper ML, Muscat JE, Lazarus P, Scheet P, Moore JH, Chen Y.

Genet Epidemiol. 2017 Dec;41(8):876-886. doi: 10.1002/gepi.22085. Epub 2017 Nov 7.


Differentially DNA methylation changes induced in vitro by traffic-derived nanoparticulate matter.

Lei X, Muscat JE, Zhang B, Sha X, Xiu G.

Toxicology. 2018 Feb 15;395:54-62. doi: 10.1016/j.tox.2017.11.005. Epub 2017 Nov 3.


Sex/Gender Differences in Cotinine Levels Among Daily Smokers in the Pennsylvania Adult Smoking Study.

Chen A, Krebs NM, Zhu J, Sun D, Stennett A, Muscat JE.

J Womens Health (Larchmt). 2017 Nov;26(11):1222-1230. doi: 10.1089/jwh.2016.6317. Epub 2017 Sep 5.


Reduced nicotine content cigarettes in smokers of low socioeconomic status: study protocol for a randomized control trial.

Krebs NM, Allen SI, Veldheer S, Martinez DJ, Horn K, Livelsberger C, Modesto J, Kuprewicz R, Wilhelm A, Hrabovsky S, Kazi A, Fazzi A, Liao J, Zhu J, Wasserman E, Reilly SM, Reinhart L, Trushin N, Moyer RE, Bascom R, Foulds J, Richie JP Jr, Muscat JE.

Trials. 2017 Jul 3;18(1):300. doi: 10.1186/s13063-017-2038-9. Erratum in: Trials. 2017 Dec 15;18(1):598.


Analysis of single nucleotide variants of HFE gene and association to survival in The Cancer Genome Atlas GBM data.

Lee SY, Zhu J, Salzberg AC, Zhang B, Liu DJ, Muscat JE, Langan ST, Connor JR.

PLoS One. 2017 Mar 30;12(3):e0174778. doi: 10.1371/journal.pone.0174778. eCollection 2017.


A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol.

Allen SI, Foulds J, Pachas GN, Veldheer S, Cather C, Azzouz N, Hrabovsky S, Hameed A, Yingst J, Hammett E, Modesto J, Krebs NM, Zhu J, Liao J, Muscat JE, Richie J, Evins AE.

BMC Public Health. 2017 Jan 19;17(1):100. doi: 10.1186/s12889-016-3946-4.


Comparison of Puff Volume With Cigarettes per Day in Predicting Nicotine Uptake Among Daily Smokers.

Krebs NM, Chen A, Zhu J, Sun D, Liao J, Stennett AL, Muscat JE.

Am J Epidemiol. 2016 Jul 1;184(1):48-57. doi: 10.1093/aje/kwv341. Epub 2016 Jun 16.


Effect of smoking reduction and cessation on the plasma levels of the oxidative stress biomarker glutathione--Post-hoc analysis of data from a smoking cessation trial.

Mons U, Muscat JE, Modesto J, Richie JP Jr, Brenner H.

Free Radic Biol Med. 2016 Feb;91:172-7. doi: 10.1016/j.freeradbiomed.2015.12.018. Epub 2015 Dec 18.


Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks.

Jones NR, Ashmore JH, Lee SY, Richie JP, Lazarus P, Muscat JE.

Cancers (Basel). 2015 Dec 9;7(4):2386-96. doi: 10.3390/cancers7040898.


No Association Between Vitamin D Intake, VDR Polymorphisms, and Colorectal Cancer in a Population-Based Case-Control Study.

Ashmore JH, Gallagher CJ, Lesko SM, Muscat JE, Hartman TJ, Lazarus P.

Cancer Epidemiol Biomarkers Prev. 2015 Oct;24(10):1635-7. doi: 10.1158/1055-9965.EPI-15-0284. Epub 2015 Jul 29.


Lower lung cancer rates in Jewish smokers in Israel and the USA.

Rennert G, Kremer R, Rennert HS, Wollner M, Agbarya A, Pinchev M, Lejbkowicz F, Spitz MR, Muscat JE.

Int J Cancer. 2015 Nov 1;137(9):2155-62. doi: 10.1002/ijc.29587. Epub 2015 May 18.


HFE polymorphisms affect survival of brain tumor patients.

Lee SY, Slagle-Webb B, Sheehan JM, Zhu J, Muscat JE, Glantz M, Connor JR.

J Neurooncol. 2015 Mar;122(1):97-104. doi: 10.1007/s11060-014-1681-1. Epub 2014 Dec 10.


Predictors of the Nicotine Dependence Behavior Time to the First Cigarette in a Multiracial Cohort.

Branstetter SA, Mercincavage M, Muscat JE.

Nicotine Tob Res. 2015 Jul;17(7):819-24. doi: 10.1093/ntr/ntu236. Epub 2014 Nov 27.


Education and lung cancer among never smokers.

Menvielle G, Truong T, Jellouli F, Stücker I, Brenner H, Field JK, Hosgood HD, Lan Q, Landi MT, Hung RJ, Lazarus P, McLaughlin J, Morgenstern H, Muscat JE, Ruano-Ravina A, Schwartz AG, Seow A, Spitz MR, Tardon A, Zhang ZF, Luce D.

Epidemiology. 2014 Nov;25(6):934-5. doi: 10.1097/EDE.0000000000000183. No abstract available.


NNK reduction pathway gene polymorphisms and risk of lung cancer.

Modesto JL, Hull A, Angstadt AY, Berg A, Gallagher CJ, Lazarus P, Muscat JE.

Mol Carcinog. 2015 Jun;54 Suppl 1:E94-E102. doi: 10.1002/mc.22187. Epub 2014 Jun 29.


The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions.

Angstadt AY, Hartman TJ, Lesko SM, Muscat JE, Zhu J, Gallagher CJ, Lazarus P.

Genes Chromosomes Cancer. 2014 Jun;53(6):454-66.


Randomized controlled trial of oral glutathione supplementation on body stores of glutathione.

Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE.

Eur J Nutr. 2015 Mar;54(2):251-63. doi: 10.1007/s00394-014-0706-z. Epub 2014 May 5.


Development of a genotyping microarray for studying the role of gene-environment interactions in risk for lung cancer.

Baldwin DA, Sarnowski CP, Reddy SA, Blair IA, Clapper M, Lazarus P, Li M, Muscat JE, Penning TM, Vachani A, Whitehead AS.

J Biomol Tech. 2013 Dec;24(4):198-217. doi: 10.7171/jbt.13-2404-004.


Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study.

Ashmore JH, Lesko SM, Muscat JE, Gallagher CJ, Berg AS, Miller PE, Hartman TJ, Lazarus P.

Genes Chromosomes Cancer. 2013 Oct;52(10):945-53. doi: 10.1002/gcc.22089. Epub 2013 Jul 26.


Time to first cigarette predicts cessation outcomes in adolescent smokers.

Mercincavage M, Branstetter SA, Muscat JE, Horn KA.

Nicotine Tob Res. 2013 Dec;15(12):1996-2004. doi: 10.1093/ntr/ntt087. Epub 2013 Jun 28.


The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk.

Angstadt AY, Berg A, Zhu J, Miller P, Hartman TJ, Lesko SM, Muscat JE, Lazarus P, Gallagher CJ.

Cancer. 2013 Jul 1;119(13):2477-85. doi: 10.1002/cncr.28009. Epub 2013 Apr 10.


Time to first cigarette and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) levels in adult smokers; National Health and Nutrition Examination Survey (NHANES), 2007-2010.

Branstetter SA, Muscat JE.

Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):615-22. doi: 10.1158/1055-9965.EPI-12-0842. Epub 2013 Mar 29.


Association of dietary and supplemental iron and colorectal cancer in a population-based study.

Ashmore JH, Lesko SM, Miller PE, Cross AJ, Muscat JE, Zhu J, Liao J, Harper G, Lazarus P, Hartman TJ.

Eur J Cancer Prev. 2013 Nov;22(6):506-11. doi: 10.1097/CEJ.0b013e32836056f8.


Meat-related compounds and colorectal cancer risk by anatomical subsite.

Miller PE, Lazarus P, Lesko SM, Cross AJ, Sinha R, Laio J, Zhu J, Harper G, Muscat JE, Hartman TJ.

Nutr Cancer. 2013;65(2):202-26. doi: 10.1080/01635581.2013.756534.


Menthol cigarettes and lung cancer mortality.

Muscat JE.

Nicotine Tob Res. 2012 Oct;14(10):1246-7; author reply 1248. No abstract available.


Time to first cigarette and serum cotinine levels in adolescent smokers: National Health and Nutrition Examination Survey, 2007-2010.

Branstetter SA, Muscat JE.

Nicotine Tob Res. 2013 Mar;15(3):701-7. doi: 10.1093/ntr/nts189. Epub 2012 Sep 18.


Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium.

Brenner DR, Boffetta P, Duell EJ, Bickeböller H, Rosenberger A, McCormack V, Muscat JE, Yang P, Wichmann HE, Brueske-Hohlfeld I, Schwartz AG, Cote ML, Tjønneland A, Friis S, Le Marchand L, Zhang ZF, Morgenstern H, Szeszenia-Dabrowska N, Lissowska J, Zaridze D, Rudnai P, Fabianova E, Foretova L, Janout V, Bencko V, Schejbalova M, Brennan P, Mates IN, Lazarus P, Field JK, Raji O, McLaughlin JR, Liu G, Wiencke J, Neri M, Ugolini D, Andrew AS, Lan Q, Hu W, Orlow I, Park BJ, Hung RJ.

Am J Epidemiol. 2012 Oct 1;176(7):573-85. Epub 2012 Sep 17.


A functional trinucleotide repeat polymorphism in the 5'-untranslated region of the glutathione biosynthetic gene GCLC is associated with increased risk for lung and aerodigestive tract cancers.

Nichenametla SN, Muscat JE, Liao JG, Lazarus P, Richie JP Jr.

Mol Carcinog. 2013 Oct;52(10):791-9. doi: 10.1002/mc.21923. Epub 2012 May 18.


Menthol smoking in relation to time to first cigarette and cotinine: results from a community-based study.

Muscat JE, Liu HP, Stellman SD, Richie JP Jr.

Regul Toxicol Pharmacol. 2012 Jun;63(1):166-70. doi: 10.1016/j.yrtph.2012.03.012. Epub 2012 Apr 2.


Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium.

Coté ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Aben KK, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, Brenner H, Duell EJ, Fabianova E, Field JK, Foretova L, Friis S, Harris CC, Holcatova I, Hong YC, Isla D, Janout V, Kiemeney LA, Kiyohara C, Lan Q, Lazarus P, Lissowska J, Le Marchand L, Mates D, Matsuo K, Mayordomo JI, McLaughlin JR, Morgenstern H, Müeller H, Orlow I, Park BJ, Pinchev M, Raji OY, Rennert HS, Rudnai P, Seow A, Stucker I, Szeszenia-Dabrowska N, Dawn Teare M, Tjønnelan A, Ugolini D, van der Heijden HF, Wichmann E, Wiencke JK, Woll PJ, Yang P, Zaridze D, Zhang ZF, Etzel CJ, Hung RJ.

Eur J Cancer. 2012 Sep;48(13):1957-68. doi: 10.1016/j.ejca.2012.01.038. Epub 2012 Mar 19.


The nicotine dependence phenotype, time to first cigarette, and larynx cancer risk.

Muscat JE, Liu HP, Livelsberger C, Richie JP Jr, Stellman SD.

Cancer Causes Control. 2012 Mar;23(3):497-503. doi: 10.1007/s10552-012-9909-x. Epub 2012 Feb 25.

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